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Aline Charabaty Lab
The Aline Charabaty Lab performs clinical research on Inflammatory Bowel Disorder.
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Alyssa Parian Lab
The Alyssa Parian Lab works to identify early markers of dysplasia. We also study inflammatory bowel disease-associated cancers, conduct IBD clinical trials and examine IBD extraintestinal manifestations.
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Amy Kim Lab
The Amy Kim Lab performs basic, translational, and clinical research on liver lesions and hepatocellular carcinoma.
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Anne Marie Lennon Lab
The Lennon Lab does clinical and translational research on endoscopic ultrasound, esophageal cancer, gastric cancer, gastroenterology, pancreatic cancer, pancreatic cysts, therapeutic endoscopy, Von Hippel-Lindau (VHL)
Principal Investigator
Anne Marie O'Broin Lennon, M.B.B.Ch., Ph.D.
Department
Medicine
Oncology
Radiology and Radiological Science
Surgery
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Ashish Nimgoankar Lab
The Ashish Nimgoankar Lab is interested in translational technology development and image-guided therapies.
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Brindusa Truta Lab
The Brindusa Truta Lab studies inflammatory bowel diseases, specifically Crohn’s disease and ulcerative colitis. Recent studies defined factors associated with the development of Crohn's disease after ileal pouch anal anastomosis; determined the value of histology in identifying Lynch syndrome in early-onset of colorectal cancer patients; and compared the phenotype and genotype in adenomatous polyposis patients with and without a family history.
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Center for Epithelial Disorders
The Johns Hopkins Center for Epithelial Disorders focuses on research into the physiology and pathophysiology of epithelial cells (cells that line the cavities and interior surfaces of the body) of the gastrointestinal (GI) tract, liver, pancreas and kidney. Specifically, the center’s research seeks to:
-Understand the mechanisms regulating the activity of transport proteins (including channels) of epithelial cells
Characterize the mechanisms by which polarity of epithelial cells are maintained
-Investigate the mechanisms controlling transcription of epithelial-specific genes
Understand the pathophysiological basis of GI and renal diseases that involve the preceding three components
-The center also provides a framework for training fellows in gastroenterology and hepatology to become independent investigators.
The center is funded primarily through individual investigator-initiated extramural research grant support from the National Institutes of Health (NIH) as well as mult...i-investigator grants including RO1, PO1, UO1 and R24. view more -
Chung-Ming Tse
The Tse Lab does basic and translational research on the function and regulation of sodium/hydrogen exchange-2 isoform, and molecular biology of nucleoside transporters.
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Cynthia Sears Laboratory
Work in the Cynthia Sears Laboratory focuses on the bacterial contributions to the development of human colon cancer and the impact of the microbiome on other cancers and the therapy of cancer. The current work involves mouse and human studies to define how enterotoxigenic Bacteroides fragilis, pks+ Escherichia coli, Fusobacterium nucleatum, biofilms and the colonic microbiota induce chronic colonic inflammation and colon cancer. Prospective human studies of the microbiome and biofilms in screening colonoscopy are in progress as are studies to determine if and how the microbiome impacts the response of individuals with cancer to immunotherapy and other cancer therapies.
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Doan Dao Lab
The Doan Dao Lab performs clinical research on Hepatitis B.
