Dr. Foulke-Abel’s research focuses on finding drugs to cure the diarrheal diseases, including cholera, E. coli and rotavirus infection. Her work utilizes 3D organoids her team has grown from intestinal stem cells to recapitulate all of the segments of the human gut.
Learn more about clinical trials at Johns Hopkins Medicine.
Zachos NC, Kovbasnjuk O, Foulke-Abel J, In J, Blutt SE, de Jonge HR, Estes MK, Donowitz M. “Human enteroids/colonoids and intestinal organoids functionally recapitulate normal intestinal physiology and pathophysiology.” J Biol Chem. 2016 Feb 19;291(8):3759–66. doi: 10.1074/jbc.R114.635995. PMID: 26677228.