Marcia Irene Canto, M.D., M.H.S.

Headshot of Marcia Irene Canto
  • Director of Clinical Research, Division of Gastroenterology
  • Professor of Medicine

Languages: English, Filipino, Tagalog


Barrett's Esophagus, Chest Pain, Digestive Disorders, Endoscopic Ultrasound, Endoscopy, Esophageal Cancer, Family History of Cancer, Gastroenterology, Gastroesophageal Reflux Disease (GERD), Gastrointestinal Cancers, Heartburn, Hiatal Hernia, Hoarseness, Pancreatic and Biliary Disease, Pancreatic Cancer, Pancreatic Cysts, Reflux and Burning, Therapeutic Endoscopy, Transoral Incisionless Fundoplications (TIF) more

Research Interests

Familial pancreatic cancer; Barrett's esophagus; Endoscopic mucosal ablation and resection; Cryotherapy; Cryoablation; Endoscopic imaging more

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The Johns Hopkins Hospital (Main Entrance)

Appointment Phone: 410-933-7495
1800 Orleans St.
Baltimore, MD 21287
The Johns Hopkins Hospital (Main Entrance) - Google Maps

Johns Hopkins Gastroenterology and Hepatology - Howard County

Appointment Phone: 410-933-7495
5450 Knoll North Drive
Suite 390
Columbia, MD 21045
Johns Hopkins Gastroenterology and Hepatology - Howard County - Google Maps


Marcia (Mimi) Canto, M.D., M.H.S. is a Professor of Medicine at The Johns Hopkins University School of Medicine. She is also the Director of Endoscopy at the Johns Hopkins Hospital. Dr. Canto received her Bachelor of Science degree from the University of the Philippines in Manila in 1981 (summa cum laude). She received her Doctor of Medicine degree in 1985 from the University of the Philippines and completed her training in Internal Medicine from State University of New York Sciences Center in Brooklyn, Brooklyn, New York.

Dr. Canto completed a postdoctoral fellowship in Gastroenterology-Hepatology at The Johns Hopkins University School of Medicine and received a Master of Health Science in Clinical Epidemiology from The Johns Hopkins University School of Hygiene and Public Health in 1993. Dr. Canto came back to Johns Hopkins after spending three years at Case Western Reserve University in Cleveland, Ohio for advanced endoscopic training.

Her primary clinical interests include endoscopy, particularly the use of endoscopic ultrasound (EUS) in detecting early pancreatic cancer and its precursors. She has recently shown that endoscopic ultrasound can be used to detect asymptomatic precancerous lesions in patients with a family history of pancreatic cancer. more


  • Director of Clinical Research, Division of Gastroenterology
  • Professor of Medicine
  • Professor of Oncology

Departments / Divisions

Centers & Institutes



  • MD; University of the Philippines College of Medicine (1985)


  • Internal Medicine; SUNY Downstate Medical Center (1990)


  • Gastroenterology; Case Western Reserve University Hospitals (1995)
  • Gastroenterology; Johns Hopkins University School of Medicine (1993)
  • Gastroenterology; University of California at Irvine School of Medicine (1995)

Board Certifications

  • American Board of Internal Medicine (Internal Medicine) (1989)

Research & Publications

Clinical Trial Keywords

GERD, Transoral incisionless fundoplication (TIF/cTIF)

Selected Publications

View all on PubMed

Wang, J.S.; Guo, M.; Montgomery, E.A.; Thompson, R.E.; Cosby, H.; Hicks, L.; Wang, S.; Herman, J.G.; Canto, M.I. DNA promoter hypermethylation of p16 and APC predicts neoplastic progression in Barrett's esophagus. Am J Gastroenterol. 2009 Sep;104(9):2153-2160

Brune, K.A.; Lau, B.; Palmisano, E.; Canto, M.; Goggins, M.G.; Hruban, R.H.; Klein, A.P. Importance of age of onset in pancreatic cancer kindreds. J Natl Cancer Inst. 2010 Jan 20;102(2):119-126

Harinck, F.; Canto, M.I.; Schulick, R.; Goggins, M.; Poley, J.W.; Fockens, P.; Kluijt, I.; Bruno, M. Surveillance in individuals at high risk of pancreatic cancer: too early to tell? Gut. 2010 Jul;59(7):1005; author reply 1006-1007

Hector, A.; Montgomery, E.A.; Karikari, C.; Canto, M.; Dunbar, K.B.; Wang, J.S.; Feldmann, G.; Hong, S.M.; Haffner, M.C.; Meeker, A.K.; Holland, S.J.; Yu, J.; Heckrodt, T.J.; Zhang, J.; Ding, P.; Goff, D.; Singh, R.; Roa, J.C.; Marimuthu, A.; Riggins, G.J.; Eshleman, J.R.; Nelkin, B.D.; Pandey, A.; Maitra, A. The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma. Cancer Biol Ther. 2010 Nov 29;10(10):1009-1018

Hruban, R.H.; Canto, M.I.; Goggins, M.; Schulick, R.; Klein, A.P. Update on familial pancreatic cancer. Adv Surg. 2010;44:293-311

Lennon, A.M.; Newman, N.; Makary, M.A.; Edil, B.H.; Shin, E.J.; Khashab, M.A.; Hruban, R.H.; Wolfgang, C.L.; Schulick, R.D.; Giday, S.; Canto, M.I. EUS-guided tattooing before laparoscopic distal pancreatic resection (with video). Gastrointest Endosc. 2010 Nov;72(5):1089-1094

Newman, N.A.; Lennon, A.M.; Edil, B.H.; Gilson, M.M.; Giday, S.A.; Canto, M.I.; Schulick, R.D.; Makary, M.A. Preoperative endoscopic tattooing of pancreatic body and tail lesions decreases operative time for laparoscopic distal pancreatectomy. Surgery. 2010 Aug;148(2):371-377

Videos & Media

Recent News Articles and Media Coverage

Mentoring Women in Medicine, Inside Tract (Winter, 2020)

For Acid Reflux: An Innovative Alternative to Surgery, Inside Tract (Summer 2018)

Endoscopic Cryotherapy: A Cool Alternative, Inside Tract (Spring 2015) 

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