Cardiovascular disease continues to be the leading cause of death in the US. About 1,400,000 people die from cardiovascular disease annually. The American Heart Association estimates that 2,600 Americans die of cardiovascular disease every day. At Johns Hopkins, faculty with a particular interest in cardiovascular disease are approaching both primary and secondary prevention modalities in high risk populations, including families with premature coronary disease, people with hypertension and or obesity, and an urban community population. Studies range from genetic and molecular studies of the mechanisms of cardiovascular disease to studies of vascular properties, lifestyle interventions, and responsiveness to preventive pharmacotherapy. We also have a broad interest in the context in which intervention and prevention strategies are employed, including medical environments, alternative care systems in communities, and self-help. A considerable portion of our work is focused on genetic epidemiology and gene-environment interactions. Hopkins GIM brings together experts in cardiovascular and related research on the Hopkins campus, including faculty from Cardiology (Drs. Lewis Becker, Brian G. Kral, Jeffrey Brinker, Pamela Ouyang, and Kerry J. Stewart), Critical Care Medicine and thrombosis research (Dr. Nauder Faraday), Neurology (Dr. Paul Nyquist), Radiology (Dr. Elliott K. Fishman), Neuroradiology (Dr. David Yousem), Genetic epidemiology (Drs. M. Daniele Fallin and Rasika Mathias), and Endocrinology (Dr. Rita Kalyani). Drs. Linzhao Cheng and Zack Wang from the Institute for Cell Engineering are members of our research Division research team.