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School of Medicine
Infection and Complication Reduction Projects
Below is a selection of our current and past projects around reducing infections and complications.
AHRQ Safety Program for Improving Surgical Care and Recovery
Project Dates: Sept. 30, 2016–Sept. 29, 2021
This national program, in collaboration with the American College of Surgeons, is guiding hundreds of U.S. hospitals to implement perioperative evidence-based pathways to improve clinical outcomes, reduce hospital length of stay and enhance the patient experience. Funded by Agency for Healthcare Research and Quality (AHRQ).
AHRQ Safety Program for Improving Antibiotic Use
Project Dates: Sept. 2, 2016–Sept. 1, 2021
The Armstrong Institute, in collaboration with NORC at the University of Chicago, is working with hundreds of hospitals, ambulatory practices and long-term care facilities across the United States to reduce antibiotic-related harms, such as Clostridium infections, and prevent the spread of antimicrobial-resistant organisms. Funded by AHRQ.
Using Human Factors Approaches to Discover New Strategies to Improve Environmental Cleaning within the Hospital Setting
Project Dates: Sept. 30, 2015–Sept. 29, 2018
This project is developing a scalable, multifaceted and novel intervention package to improve patient room cleanliness in order to prevent transmission of pathogens. Funded by CDC Prevention Epicenters Program.
CUSP for Mechanically Ventilated Patients
Project Dates: Sept. 23, 2013–Sept. 22, 2016
This national collaborative project sought to improve outcomes for patients on breathing machines. The program focused on preventing short-term harms, such as ventilator-associated pneumonia, as well as long-term harms that can persist long after a hospital stay, including cognitive dysfunction, anxiety and depression. Funded by AHRQ.
Applying Human Factors Approaches to Improve the Use of Personal Protective Equipment and Prevent Transmission of High-Consequence Pathogens
Project Dates: Sept. 1, 2013–Oct. 31, 2017
In an epidemic of Ebola or other high-consequence pathogens, improper removal—or doffing—of personal protective equipment (PPE) can expose health care workers to contamination. This program is evaluating the best ways for health care workers to doff PPE to prevent the spread of disease. Funded by CDC Prevention Epicenters Program.
AHRQ Safety Program for Surgery
Project Dates: Sept. 1, 2011–Aug. 31, 2015
Through this national program led by the Armstrong Institute, more than 250 hospitals across the United States worked to reduce surgical site infections and other complications. Funded by AHRQ.
On the CUSP: Stop BSI
Project Dates: Sept. 30, 2008–Sept. 29, 2012
Spanning 44 participating U.S. states, this national project showed that central line-associated bloodstream infections were entirely preventable when caregivers followed simple steps backed by evidence and when they fostered a culture of safety. Funded by AHRQ via a subcontract from the Health Research and Educational Trust.
Preventing Venous Thromboembolism (Blood Clots)
Project Dates: 2005–present
Deep vein thrombosis—a blood clot in a deep vein—and pulmonary embolism—a blood clot that travels to the lungs—together comprise the most common preventable cause of hospital-related death. The Johns Hopkins Venous Thromboembolism Collaborative has followed a systemic approach to the challenge of translating the evidence about prevention into everyday bedside practice. Funded by Johns Hopkins Medicine.