Organ Systems Foundations of Medicine

The Organ Systems Foundations of Medicine (OSFM) extends from January of Year One through February of Year Two. This phase of the curriculum presents an integrated understanding of human health and disease, using the framework of physiologic systems. Several scientific disciplines, such as biochemistry, cell biology, epidemiology, pathology and pharmacology, are presented in each system. Relevant Horizontal Strands are also integrated into each OSFM course. Each course uses a combination of lecture, readings, small-group problem-solving, virtual microscopy, pathology laboratories and student-led workshops to achieve learning goals.

Course Goals

The two main course goals are:

  • Use the scientific foundations to understand the origins, manifestations, impact and treatment of disease or risk of disease
  • Advance students’ professional identity by acquiring the language, problem-solving skills, inquisitiveness, leadership, compassion and teamwork needed in a physician

Course Structure

The systems are organized into thirteen courses.

Year One

  • Block 1: OFSM: Immunology, Microbiology and Infectious Disease, Dermatology, Hematology/Oncology
  • Block 2: OFSM: Brain, Mind and Behavior, Nervous System and Special Senses

Year Two

  • Block 3: OFSM: Pulmonary, Renal, Cardiovascular
  • Block 4: OFSM:  GI/Liver, Endocrine, Reproductive, Musculoskeletal

The course directors for the Genes to Society Course are Henry Fessler, M.D., and Michael Borowitz, M.D. Each section has a section leader who plans the pedagogy for that section.

Course Directors

  • Michael Joseph Borowitz, M.D., Ph.D.

    • Director, Division of Hematologic Pathology
    • Co-Director, Genes to Society
    • Deputy Director, Education, Department of Pathology
    • Executive Deputy Director, Department of Pathology
    • Professor of Pathology
    • Professor of Oncology
  • Henry Eric Fessler, M.D.

    • Director of Education, Division of Pulmonary and Critical Care
    • Professor of Medicine

OSFM Immunology

  • Stuart Campbell Ray, M.D.

    • Vice Chair of Medicine for Data Integrity and Analytics, Department of Medicine
    • Research Subcouncil Co-Chair of the JHM Data Trust
    • Assistant Dean of Research
    • Professor of Medicine
    • Professor of Oncology
  • Jonathan Schneck, M.D., Ph.D.

    • Professor of Pathology
    • Professor of Biomedical Engineering
    • Professor of Oncology

OSFM Microbiology and Infectious Disease

  • Karen C. Carroll, M.D.

    • Director, Division Medical Microbiology
    • Director, ACGME Accredited Medical Microbiology Fellowship Program
    • Section Director Molecular Epidemiology, Rapid Response Laboratory
    • Associate Director, Bacteriology Laboratory
    • Professor of Pathology
    • Joint Appointment in Medicine
  • Khalil Georges Ghanem, M.D., Ph.D.

    • Deputy Director of Education, Department of Medicine, Johns Hopkins Bayview Medical Center
    • Professor of Medicine
  • Maunank R Shah, M.D.

    • Professor of Medicine

OSFM Dermatology

Farah Succaria, M.D.

  • Assistant Professor of Dermatology

OSFM Hematology/Oncology

OSFM Brain, Mind and Behavior

  • Vinay Kishor Parekh, M.D.

    • Director of the Core Clerkship in Psychiatry, The Johns Hopkins University School of Medicine
    • Co-Medical Director, Johns Hopkins Broadway Center for Addiction
    • Assistant Director, Adult Psychiatric Emergency Services, The Johns Hopkins Hospital
    • Assistant Professor of Psychiatry and Behavioral Sciences
  • Claire Price Zachik, M.D.

    • Instructor of Psychiatry and Behavioral Sciences

OSFM Nervous System and Special Senses

Arun Venkatesan, M.D., Ph.D.

  • Professor of Neurology

Mary Ann Wilson, Ph.D.
Associate Professor of Neurology


Natrell Miller Darden
Medical Training Program Administrator
Email: [email protected] 

For Dermatology:

Marsha Mackey
CO Sr. Administrative Manager
Email: [email protected]

Time Commitment and Course Length

The course runs for 23 weeks.