Dr. McMahon, who has a Ph.D. in Chemical Physics from University of Illinois Urbana-Champaign (1999). He has been a member of the Radiology Faculty (MR Division) at Johns Hopkins since 2003. He is recognized internationally for his work on chemical exchange saturation transfer (CEST) MRI contrast agents that are used for cancer and kidney imaging. In particular, he is recognized for developing techniques to measure chemical exchange rates; introducing the concept of multiple-color MRI; and discovering imidazoles and salicylates which have outstanding MRI contrast properties. He is the lead editor of the only textbook on CEST MRI “Chemical Exchange Saturation Transfer Imaging: Advances and Applications”.
Dr. McMahon is a highly accomplished, world-recognized, established investigator in MRI research who works regularly at the intersection of the School of Medicine and the Kennedy Krieger Institute, as Director of the Laboratory of Biodegradable Contrast Agents. With his collaborators, Dr. McMahon has demonstrated the utility of CEST MRI in preclinical models of breast, brain, prostate and colon cancer, methyl malonic acidemia and urinary tract obstructions, and has mentored more than 15 students and postdoctoral fellows. He has held continuous funding since his initial appointment as an Assistant Professor in 2006, with numerous NIH grants supporting his research. Dr. McMahon currently has an NIH R01, is a project principal investigator on the Molecular Imaging in Precision Medicine P41 NIH resource center grant, and a collaborator on three other R01s.
In recognition of his substantial achievements in CEST MRI, Dr. McMahon was elected as Secretary (2018), Vice Chair (2019) and Chair (2020) of ISMRM’s Molecular Imaging Study Group and has also served on ISMRM’s workshop organizing committee. Furthermore, Dr. McMahon was lead organizer of an international workshop on CEST imaging held in Annapolis, MD in 2012 and co-organizer of a workshop on MRI based molecular imaging in St. John’s, Newfoundland in 2019. Dr. McMahon has served many times as a moderator, invited speaker, and discussion leader in ISMRM annual meetings, World Molecular Imaging Society annual meetings and workshops. He has reviewed manuscripts for over 40 journals and abstracts for numerous conferences; serves on the editorial board of Magnetic Resonance Letters; reviews grant applications for several NIH panels, the European Research Council, the Netherlands Organisation for Scientific Research, the National Sciences and Engineering Research Council of Canada, the Israel Science Foundation, and the National Science Centre of Poland.