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Research Cores and Center Directory

Adherence Research Center (JHARC)

The Johns Hopkins Adherence Research Center (JHARC) is a leader in the design of innovative interventions to promote adherence and the measurement and evaluation of adherence within clinical trials. Over the last two decades, JHARC has been conducting studies of adherence measurement and promotion interventions. JHARC has received continuous NIH funding for studies related to the measurement of adherence and self-management interventions. In addition to investigator-initiated studies, JHARC faculty members consult with the pharmaceutical industry, nonprofit organizations, and faculty at other academic institutions. JHARC is an international leader in the development and use of electronic medication monitoring devices. Projects have included a broad age range (preschool to geriatrics) and a wide variety of illnesses (e.g., asthma, cystic fibrosis, CKD, cardiovascular disease, and diabetes). JHARC faculty are particularly interested in identifying and addressing factors associated with health disparities. 

For more information, contact Elizabeth Ruvalcaba, Senior Research Coordinator in Pulmonary and Critical Care Medicine, at eruvalc1@jhmi.edu.


Bayview Immunomics Core (BIC)

BIC was initially established in 2008 as a flow cytometry core to meet the biomedical research needs of Bayview’s investigators. This core is embedded among research groups interested in problems affiliated with immune-based human diseases and relevant animal models, and promotes an interactive collaboration approach. BIC has an extensive research base and considerable expertise in flow-based approaches to address neuro-science related research. The core has since expanded to include immuno-assays and genomics services. 

For more information, contact Rafaello Cimbro, Lab Manager in Rheumatology, at rcimbro1@jhmi.edu.


Biostatistics, Epidemiology & Data Management (BEAD) Core

The BEAD Core provides research support services to new and established faculty investigators on the Johns Hopkins Bayview campus. Johns Hopkins Bayview faculty receive free (up to 20 hours) services through the generous support of the vice dean David Hellmann, M.D. The core also accepts direct fee-for-service work. Core services include:

  • Biostatistical analyses

  • Database development and maintenance
  • Epidemiologic study design support
  • Power and sample size calculations
  • Statistical analytic plans for grant submissions

For more information or to set up an appointment, contact BEADCore@jhmi.edu or visit jhcchr.org/bead.

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Center for Interdisciplinary Sleep Research & Education (CISRE)

CISRE is an interdisciplinary program that supports clinical research and education related to Sleep Medicine at Johns Hopkins Medical Institutions and off-site multi-centered clinical trials. CISRE leverages the expertise and resources of sleep specialists and their colleagues in a wide range of medical disciplines to facilitate state-of-the-art interdisciplinary initiatives in research and education in Sleep Medicine. CISRE includes a 10-bed sleep research center with an on-site chronobiology suite, an NIH-funded T32 training program in multidisciplinary sleep medicine, and dedicated sleep IT infrastructure. Its multifaceted AASM-accredited scoring hub and data management core are available to support single and multi-center clinical trials in the sleep arena.

For more information, please contact Una McCann via this webpage.

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Centro SOL

The Center for Salud/Health and Opportunity for Latinos aims to promote equity in health and opportunity for Latinos by advancing clinical care, research, education and advocacy at Johns Hopkins and beyond in active partnership with local organizations. Each component is integrated by faculty, staff and students from Hopkins and community leaders.

Centro SOL offers support services to Johns Hopkins teams that want to engage Latino populations in research. Services include tailoring study design and recruitment to the local Latino population, translation of study documents, IRB application preparation related to the inclusion of limited-English-proficiency populations and assessments of linguistic and cultural suitability of study materials. Research services faculty and staff are also available to play a larger role and collaborate on projects and funding applications where appropriate.

For more information on engaging Centro SOL Research support services, pricing, policies or to schedule an initial consult, please email centrosol@jhmi.edu

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Genetic Resources Core Facility

The Genetic Resources Core Facility (GRCF) is a JHU service center including the Core Store, Biorepository & Cell Center and the DNA Services.  Collectively, these groups produce a number of products and services to aid researchers performing studies in molecular biology and genetics.  The core’s mission is to provide high quality, cost effective research services and products to investigators throughout the Johns Hopkins Scientific Community.

  • Biorepository & Cell Center facilitates CAP accredited clinical and basic scientific research by providing expertise and service in blood and biomaterial processing, mammalian cell culture, single cell genomics, cryogenic storage and national/ international shipping.
  • Core Store provides one-stop shopping for more than 400,000 products from 17 of the leading life science companies.  In addition to its product offering the store charges no shipping and handling fees and has free delivery to three campuses East Baltimore, Bayview and Homewood. There is also convenient 24/7 access to several hundred products via the Core Store 24/7 at these locations Blalock 1026, CRB I B02A and the Asthma and Allergy Building 1A.C4.
  • The DNA Services group works together to provide solutions for all of your DNA and RNA needs.  We handle basic needs like DNA isolation, plating and storage, “traditional” core services like Sanger sequencing, PCR support and genotyping, and the more complex needs presented by the constantly changing field of next generation sequencing.

For hours, locations, and contact information, click here.

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Institute for Clinical and Translational Research (ICTR)

The Clinical and Translational Science Award (CTSA) is a resource granted by NIH that supports the Johns Hopkins ICTR. The ICTR supports the Clinical Research Unit (CRU) on the Johns Hopkins Bayview campus and the CRUs on The Johns Hopkins Hospital campus.

The Johns Hopkins Bayview CRU (located on the fourth floor of the 301 building) provides clinical research infrastructure resources including dedicated research nursing and specimen processing, a Sleep Research Core, Cardiovascular Imaging Core, Body Composition and Exercise Core, nutrition research support, and a core laboratory. Parking for research participants is available adjacent to the 301 building. Support for informatics and biostatistics is also available through the ICTR.

For more information, contact Nicole Cooper, CRU Sr. Administrative Manager at 410-550-1880 or ncooper2@jhmi.edu.  
 

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International Center for Orthopaedic Advancement

The International Center for Orthopaedic Advancement brings together engineers and clinicians in one location as part of a multidisciplinary team of professionals dedicated to advancing patient care.  The center provides the opportunity for:

  • Surgical Training
  • Basic Research
  • Commercial Research and Development

For more information, please call 410-550-6482.

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Memory and Alzheimer's Treatment Center

The Memory and Alzheimer's Treatment Center is a collaborative partnership between the departments of psychiatry, neurology, and geriatric medicine that offers comprehensive evaluation and innovative treatment to patients with a range of conditions that affect cognition and memory, including Alzheimer's disease and other dementias, traumatic brain injury, and brain vascular disease.

For contact information about clinics, research, or community outreach, click here.

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Mouse Phenotyping & Physiology Core (MPPC)

The MPPC at Johns Hopkins Bayview’s Asthma & Allergy Center provides measurement of several metabolic parameters including: energy expenditure, locomotor behavior, food intake, body composition, glucose and insulin tolerance, and insulin sensitivity in mice and rats. The assets of the MPPC include state-of-the-art instrumentation and a nationally recognized staff.   MPPC currently provides the following services:

  • Acute and Chronic Metabolic Monitoring: utilizing Oxymax Comprehensive Laboratory Animal Monitoring System (CLAMS) and treadmill for oxygen consumption, carbon dioxide release, sleep epoch, locomotor activity and food intake
  • Body composition measurement of lean and fat mass: Nuclear Magnetic Resonance (NMR)
  • Glucose Homeostasis Assessment: Glucose and Pyruvate Tolerance Tests
  • Euglycemic-Hyperinsulin Clamp: 3H and C-14 tracers thus giving researchers access to a broad range of metabolic tests
  • Serum and Plasma Analysis:  Analyses of glucose, ketones, leptin, resistin, triglycerides, cholesterol, non-esterified fatty acids, total protein, bilirubin, alkaline phosphate, albumin, etc.

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Older Americans Independence Center (OAIC) Research Cores

The Claude D. Pepper Center OAIC at Bayview is an NIH-sponsored research center focused on the study of the causes and consequences of frailty in older adults. The OAIC has three research cores, a training core and a pilot core that provide resources for a broad range of investigators interested in frailty and aging research:

  • The Biostatistics Core offers analytical and study development and design support, and assistance with gaining access to stored data from population data bases of older adults such as the Women’s Health and Aging Studies I and II.
  • The Molecular Measures Core supports inflammatory, mitochondrial, endocrine and other clinical and molecular based measurements, and provides animal models and stored human serum for eligible investigators.
  • The Clinical Translational Core provides access to a registry of older adults interested in participating in clinical research, and support for eligible investigators for IRB and clinical protocol development.
  • The Research & Career Development Core offers salary and research core support to junior faculty members through an annual RFA process.
  • The Pilot Core offers funding for novel projects related to frailty and aging-related biological vulnerability.

For more information on the Johns Hopkins University's Older Americans Independence Center, please contact our Administrator, Brian Buta, MHS, at bbuta@jhu.edu or call 410-502-3412.

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Psychiatry Biostatistics and Methodology Core

The mission of the Psychiatry Biostatistics and Methodology Core at Johns Hopkins Bayview is to integrate quantitative methodological expertise into the design, grant writing, conduct, analysis, and reporting of research by departmental faculty. We provide the following statistical and methodological support to members of the Department of Psychiatry and Behavioral Sciences:    

  • Statistical Teaching (Explanation of statistical methods, and help with statistical programming)
  • Experimental Design and Data Analysis (consultation to help clarify goals and identify and articulate testable hypotheses, identification of best analytical methods, advice on database setup and formatting, sample size/power calculations and data analysis and interpretation)
  • Authoring (Methods sections for grants, statistical sections for papers - writing and review, and help with presentations)

To contact, call 410-955-9884 or email datacore@jhu.edu

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Rheumatic Disease Research Core Center (RDRCC)

The Rheumatic Disease Research Core Center (RDRCC) includes a free-standing bio-assay service which affords clinical and basic science researchers the ability to investigate novel questions that could not otherwise be addressed, due to a lack of time, expertise or infrastructure. Current bio-assay services include processing of whole blood (RNA/DNA isolation, PBMC preparation or serum separation), immuno-staining of human or animal tissues, and immuno-assays, including ELISA and immuno-precipitation. The core also offers sample storage and shipping services. Sample barcoding and data management services are currently being developed.

More information can be found on the iLab site. To learn more about the bio-assay core and its services, contact Laura Gutierrez, M.D., at 410-550-1468 or lgutier3@jhmi.edu.

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