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The Neuroregeneration Program

Neurodegenerative and neurodevelopmental diseases, stroke and traumatic brain injury are devastating conditions. The development of new treatment relies on coaxing remaining cells in the brain and nervous system to repair and replace injured or damaged cells. The Neuroregeneration program at ICE (NeuroICE) investigates a broad range of research topics to push the field faster and closer toward clinical treatments. To this end, NeuroICE researchers study neuroregeneration, neuronal cell death and survival, cell fate specification, embryonic and adult stem cells, synapse formation, axonal and dendritic targeting, neuronal development, and regulation of gene expression. The work is relevant to many disorders of the nervous system including autism and schizophrenia, major depression, bipolar disease, Parkinson’s disease, stroke, peripheral nerve disease and chronic pain.

The Neuroregeneration Program at Johns Hopkins’ Institute for Cell Engineering

Researcher Valina Dawson introduces the Neuroregeneration Program, where scientists study causes and potential treatments for conditions such as Parkinson’s and stroke.


Photo of Dr. Seth Blackshaw, Ph.D.

Blackshaw, Seth, Ph.D.

Professor of Neuroscience
Joint Appointment in Ophthalmology
Expertise, Disease and Conditions: Neurodevelopmental Disorders, Neurogenetics, Obesity
Photo of Dr. Valina L. Dawson, Ph.D.

Dawson, Valina L., Ph.D.

Professor of Neurology
Professor of Neuroscience
Professor of Physiology
Director, Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering,
Photo of Dr. Ted M. Dawson, M.D., Ph.D.

Dawson, Ted M., M.D., Ph.D.

Professor of Neurology
Professor of Neuroscience
Professor of Pharmacology and Molecular Sciences
Director, Institute for Cell Engineering
Director, Morris K. Udall Parkinson's Disease Research Center
Leonard and Madlyn Abramson Professor in Neurodegenerative Diseases
Expertise, Disease and Conditions: Neurology, Parkinson's Disease
Photo of Dr. Han Seok Ko, M.S., Ph.D.

Ko, Han Seok, M.S., Ph.D.

Associate Professor of Neurology
Photo of Dr. Gabsang Lee, Ph.D.

Lee, Gabsang, Ph.D.

Associate Professor of Neurology
Associate Professor of Neuroscience
Expertise, Disease and Conditions: Muscular Dystrophies, Pain Management, Peripheral Nerve Disorders
Photo of Dr. Chan Hyun Na, M.S., Ph.D.

Na, Chan Hyun, M.S., Ph.D.

Assistant Professor of Neurology
Photo of Dr. George K. Essien Umanah, Ph.D.

Umanah, George K. Essien, Ph.D.

Assistant Professor of Neurology

Latest News

Images of mouse neurons from the hippocampal region of the brain.

Neurons Constantly Rewrite Their DNA
Johns Hopkins scientists have discovered that neurons are risk takers: They use minor “DNA surgeries” to toggle their activity levels all day, every day.

neurons made from iPS cells

Stem Cells Reveal How Illness-Linked Genetic Variation Affects Neurons
A genetic variation linked to schizophrenia, bipolar disorder and severe depression wreaks havoc on connections among neurons in the developing brain, a team of researchers reports.

neural stem cells form rosettes

Schizophrenia-Associated Gene Variation Affects Brain Cell Development
Johns Hopkins researchers have begun to connect the dots between a schizophrenia-linked genetic variation and its effect on the developing brain.

Botch in green brain cells

New Type Of Protein Action Found To Regulate Development
Johns Hopkins researchers report they have figured out how the aptly named protein Botch blocks the signaling protein called Notch, which helps regulate development.

mutant mouse activity by time of day

Researchers Pinpoint Protein Crucial For Development Of Biological Rhythms In Mice
Johns Hopkins researchers report that they have identified a protein essential to the formation of the tiny brain region in mice that coordinates sleep-wake cycles and other so-called circadian rhythms.