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Gastrointestinal Cancer

Gastrointestinal (GI) cancers, including colorectal and pancreatic cancers, have long been a major focus of our investigators who have completed landmark studies and comprehensive models of the molecular genetics and epigenetic (changes to the environment of genes) causes of these diseases. The multi-specialty approach, resources, and experience of the Bowel Tumor Working Group, established in the 1980s, the Pancreatic Cancer Working Group, established in 1991, and Liver Cancer Group started in 2008, has led to many new findings and incremental treatment gains in some of the most difficult of tumors. Now, this body of knowledge is being further developed and expanded through this new GI cancer-specific research program to identify the unique biological components of GI cancers, identify and assess risk factors, and develop new targeted treatments and novel methods of testing potential drug therapies. The Program Leaders are Elizabeth Jaffee, M.D, and Scott Kern, M.D.