The Institute of Basic Biomedical Sciences is home to several centralized fee-for-service facilities open to all researchers at Johns Hopkins and beyond. Visit the links below to learn more about the cutting-edge technologies available.
Core Services Supported by IBBS
Centralized Services for Metabolism Research (CSMR)
Offers shared equipment for rodent metabolic testing in controlled laboratory environments critical for accurate assessment of whole-body metabolism and animal behavior. CSMR provides 15+ years of JHM faculty experience in rodent behavior, metabolic testing, and data analysis.
The Single Cell & Transcriptomics Core
Offers Affymetrix hybridization and analysis services and databases for all experiments performed at the facility. A variety of software analysis packages and individual consulting is available.
The Network Office provides computer, software, and server support to the Institute for Basic Biomedical sciences and the Basic Science departments.
Transgenic Core Laboratory
Offers services including basic transgenic mouse development to cryopreservation and derivation of new mouse ES cell lines.
Chemical Screening at ChemCore
Offers a structurally diverse compound repository and high-throughput robotics laboratory services. ChemCore scientists will work with clients to help them optimize their enzymatic and biologic assays for 96- and 384-well formats. Operated by the High Throughput Biology Center.
Other Core Services Administered By IBBS Departments
The Microscope Facility provides access to state-of-the-art electron and fluorescence/confocal microscopes. We cover imaging needs "from centimeters to nanometers" with services ranging from high-content imaging to multiple super-resolution technologies and electron microscopy.
Biomolecular NMR Center
Research facility, encompassing the Johns Hopkins University and School of Medicine. Comprises six NMR spectrometers – four of which equipped with high sensitivity cryogenic probes – for carrying out liquid state high-resolution NMR studies of biological macromolecules.
Proteomics and Mass Spectrometry
Provides extensive mass spectrometry services for analyzing protein mixtures and purified proteins. Protein profiling using two-dimensional gel analysis and fluorescent labeling is also available.
Sequencing and Synthesis Facility
Offers DNA Sanger sequencing with available same-day turnaround; peptide synthesis and purification; primer synthesis, design and purification; NGS on the MiSeq platform
Multiphoton Imaging Core
The Multiphoton Imaging (MPI) Core in the Department of Neuroscience provides instrumentation for analyzing protein localization, protein dynamics, and protein-protein interactions with high resolution.
Eukaryotic Tissue Culture Facility
The Eukaryotic Tissue Culture facility supports JHMI researchers with the culturing of insect and mammalian cells.
Slides Production Facility for Microscopy
The Slides Production Facility core produces poly-ethylene glycol (PEG) passivated glass and quartz slides for microscopy.
The Beckman Center for Cryo-EM
The Beckman Center for Cryo-EM at Johns Hopkins was established to provide cutting edge cryo-EM to the Johns Hopkins and regional communities.
X-ray Crystallography Facility
The X-ray Crystallography Facility is a fully equipped X-ray laboratory that is maintained as a departmental facility and staffed by a full-time manager.
Pharmacology NMR Facility
To facilitate research involving small molecules, the Department maintains a Bruker Avance III 500 MHz NMR spectrometer equipped with an autosampler. The automation is configured for a convenient queue up of common 1D and 2D experiments.