The Institute of Basic Biomedical Sciences is home to several centralized fee-for-service facilities open to all researchers at Johns Hopkins and beyond. Visit the links below to learn more about the cutting-edge technologies available.
Core Services Supported by IBBS
-
Centralized Services for Metabolism Research (CSMR)
Offers shared equipment for rodent metabolic testing in controlled laboratory environments critical for accurate assessment of whole-body metabolism and animal behavior. CSMR provides 15+ years of JHM faculty experience in rodent behavior, metabolic testing, and data analysis.
-
The Single Cell & Transcriptomics Core
Offers Affymetrix hybridization and analysis services and databases for all experiments performed at the facility. A variety of software analysis packages and individual consulting is available.
-
Network Office
The Network Office provides computer, software, and server support to the Institute for Basic Biomedical sciences and the Basic Science departments.
-
Transgenic Core Laboratory
Offers services including basic transgenic mouse development to cryopreservation and derivation of new mouse ES cell lines.
-
Chemical Screening at ChemCore
Offers a structurally diverse compound repository and high-throughput robotics laboratory services. ChemCore scientists will work with clients to help them optimize their enzymatic and biologic assays for 96- and 384-well formats. Operated by the High Throughput Biology Center.
Other Core Services Administered By IBBS Departments
-
Microscope Facility
The Microscope Facility provides access to state-of-the-art electron and fluorescence/confocal microscopes. We cover imaging needs "from centimeters to nanometers" with services ranging from high-content imaging to multiple super-resolution technologies and electron microscopy.
-
Biomolecular NMR Center
Research facility, encompassing the Johns Hopkins University and School of Medicine. Comprises six NMR spectrometers – four of which equipped with high sensitivity cryogenic probes – for carrying out liquid state high-resolution NMR studies of biological macromolecules.
-
Proteomics and Mass Spectrometry
Provides extensive mass spectrometry services for analyzing protein mixtures and purified proteins. Protein profiling using two-dimensional gel analysis and fluorescent labeling is also available.
-
Sequencing and Synthesis Facility
Offers DNA Sanger sequencing with available same-day turnaround; peptide synthesis and purification; primer synthesis, design and purification; NGS on the MiSeq platform
-
Multiphoton Imaging Core
The Multiphoton Imaging (MPI) Core in the Department of Neuroscience provides instrumentation for analyzing protein localization, protein dynamics, and protein-protein interactions with high resolution.
-
Eukaryotic Tissue Culture Facility
The Eukaryotic Tissue Culture facility supports JHMI researchers with the culturing of insect and mammalian cells.
-
Slides Production Facility for Microscopy
The Slides Production Facility core produces poly-ethylene glycol (PEG) passivated glass and quartz slides for microscopy.
-
The Beckman Center for Cryo-EM
The Beckman Center for Cryo-EM at Johns Hopkins was established to provide cutting edge cryo-EM to the Johns Hopkins and regional communities.
-
X-ray Crystallography Facility
The X-ray Crystallography Facility is a fully equipped X-ray laboratory that is maintained as a departmental facility and staffed by a full-time manager.
-
Pharmacology NMR Facility
To facilitate research involving small molecules, the Department maintains a Bruker Avance III 500 MHz NMR spectrometer equipped with an autosampler. The automation is configured for a convenient queue up of common 1D and 2D experiments.