Core Services

The Institute of Basic Biomedical Sciences is home to several centralized fee-for-service facilities open to all researchers at Johns Hopkins and beyond. Visit the links below to learn more about the cutting-edge technologies available.

Core Services Supported by IBBS

  • Centralized Services for Metabolism Research (CSMR)

    Offers shared equipment for rodent metabolic testing in controlled laboratory environments critical for accurate assessment of whole-body metabolism and animal behavior. CSMR provides 15+ years of JHM faculty experience in rodent behavior, metabolic testing, and data analysis.

  • The Single Cell & Transcriptomics Core

    Offers Affymetrix hybridization and analysis services and databases for all experiments performed at the facility. A variety of software analysis packages and individual consulting is available.

  • Network Office

    The Network Office provides computer, software, and server support to the Institute for Basic Biomedical sciences and the Basic Science departments.

  • Transgenic Core Laboratory

    Offers services including basic transgenic mouse development to cryopreservation and derivation of new mouse ES cell lines.

  • Chemical Screening at ChemCore

    Offers a structurally diverse compound repository and high-throughput robotics laboratory services. ChemCore scientists will work with clients to help them optimize their enzymatic and biologic assays for 96- and 384-well formats. Operated by the High Throughput Biology Center.

Other Core Services Administered By IBBS Departments

  • Microscope Facility

    The Microscope Facility provides access to state-of-the-art electron and fluorescence/confocal microscopes. We cover imaging needs "from centimeters to nanometers" with services ranging from high-content imaging to multiple super-resolution technologies and electron microscopy.

  • Biomolecular NMR Center

    Research facility, encompassing the Johns Hopkins University and School of Medicine. Comprises six NMR spectrometers – four of which equipped with high sensitivity cryogenic probes – for carrying out liquid state high-resolution NMR studies of biological macromolecules.

  • Proteomics and Mass Spectrometry

    Provides extensive mass spectrometry services for analyzing protein mixtures and purified proteins. Protein profiling using two-dimensional gel analysis and fluorescent labeling is also available.

  • Sequencing and Synthesis Facility

    Offers DNA Sanger sequencing with available same-day turnaround; peptide synthesis and purification; primer synthesis, design and purification; NGS on the MiSeq platform

  • Multiphoton Imaging Core

    The Multiphoton Imaging (MPI) Core in the Department of Neuroscience provides instrumentation for analyzing protein localization, protein dynamics, and protein-protein interactions with high resolution.

  • Eukaryotic Tissue Culture Facility

    The Eukaryotic Tissue Culture facility supports JHMI researchers with the culturing of insect and mammalian cells.

  • Slides Production Facility for Microscopy

    The Slides Production Facility core produces poly-ethylene glycol (PEG) passivated glass and quartz slides for microscopy.

  • The Beckman Center for Cryo-EM

    The Beckman Center for Cryo-EM at Johns Hopkins was established to provide cutting edge cryo-EM to the Johns Hopkins and regional communities.

  • X-ray Crystallography Facility

    The X-ray Crystallography Facility is a fully equipped X-ray laboratory that is maintained as a departmental facility and staffed by a full-time manager.