Evidence-based Treatments and Cures for Children
Research is at the heart of all we do at Johns Hopkins All Children’s Hospital. By providing pediatric patients with access to innovative research opportunities, we help advance the diagnosis, treatment, and prevention of pediatric onset diseases and their adverse outcomes.
The Johns Hopkins All Children’s Institute for Clinical and Translational Research (ICTR), under the leadership of Director Neil Goldenberg, M.D., Ph.D., engages investigators who share a collective passion for what the clinical and translational research reveals, and also the process of how one conducts the research. This approach sets the education and training activities that the Institute conducts with residents, fellows and faculty/clinicians. The ICTR works in parallel with the Institute for Fundamental Biomedical Research (IFBR), to advance interdisciplinary research initiatives and teams that bridge the basic and clinical/translational sciences.
Johns Hopkins All Children’s Hospital is a member of the national Institute for Advanced Clinical Trials (I-ACT) for Children, and leaders within the ICTR serve on several of I-ACT’s leadership committees and task forces. A list of active and/or recently complete clinical trials can be found via clinicaltrials.gov.
More than 100 full- and part-time faculty of The Johns Hopkins University are based at Johns Hopkins All Children’s campus in St. Petersburg, Florida, and engage in clinical and translational research.
Johns Hopkins All Children’s ICTR has several research centers and programs, addressing common themes that span the organization’s existing institutes and departments:
- Early-phase clinical trials to study innovative pediatric uses of existing medications (the Center for Pediatric Early-Phase Trials)
- Support for multicenter studies (the Clinical Coordinating Center and the Data Coordinating Center)
- Research focused on pediatric health equity, in particular health care access and health outcomes (the Program in Pediatric Health Equity Research)
- Education and training programs for the next generation of clinical/translational scientists focused on child health and disease (the Center for Pediatric Clinical/Translational Research Education, Training and Engagement)
The Johns Hopkins All Children’s ICTR is integrated within the Baltimore-based Johns Hopkins Institute for Clinical and Translational Research, which receives about $15 million per year from the National Institutes of Health to support investigators as they move discoveries into practice. This institute structure enhances collaboration across Johns Hopkins Medicine campuses.
Centers and Programs
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Center for Pediatric Clinical Translational Research Training, Education, Engagement and Mentorship
Serves as an education and training resource to Johns Hopkins All Children’s principal investigators, sub-investigators and their study team members on best practices for conducting clinical research.
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Center for Pediatric Data Science and Analytic Methodology
Serves to develop, investigate, disseminate, apply, and educate other researchers and trainees on novel approaches in healthcare data science and new analytic methodologies.
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Center for Pediatric Early-Phase Trials
Serves as a resource to investigators, including helping to navigate investigators through review and approval processes and engaging the expertise of cores and shared resources to enhance efficiency and quality of early-phase trial planning and execution.
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Clinical Coordinating Center for Pediatric Multicenter Studies
Provides the infrastructure to successfully lead and conduct multicenter pediatric studies.
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Data Coordinating Center for Pediatric Multicenter Studies
Provides study design, database design, statistical analysis plan development, data management, and analytic plan execution services and expertise for multicenter studies focused on child health and disease.
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Center for Pediatric Health Equity Research
Addresses child health disparities related to maternal/child health, obesity, diabetes, sickle cell disease and adolescent health.
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Pediatric Biospecimen Innovation Center (PBIC)
Serves to improve the quality of biospecimen-driven research and accelerate biomarker discovery into faster and readily reproducible applications.
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Semester Student Research Training Program
Develops and mentors passionate students at the undergraduate and undergraduate honors levels on a career trajectory of a research professional or investigator in clinical and translational research, by providing hands-on experience coupled with a didactic curriculum.
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Summer Student Research Training Program
Develops and mentors passionate students at the undergraduate, medical school and other graduate levels on a career trajectory of a research professional or investigator in clinical and translational research.
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Community Research Advisory Board (CRAB)
Provides community input and guidance on research that takes place in community settings, or which might have a substantive impact upon the local/regional community.
Johns Hopkins All Children's Research Institute
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