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Current Research in Cornea, Cataract and External Disease

The research faculty of the Cornea, Cataract and External Disease Division at the Johns Hopkins Wilmer Eye Institute are engaged in research aimed at improving how corneal disease is diagnosed, treated and managed.

Areas of Research

Contact Lenses

  • Dr. Divya Srikumaran is researching the burden of contact lenses fittings for patients with keratoconus and similar ocular diseases.

Corneal Collagen Cross-linking

Corneal Transplantation

  • Dr. Albert Jun is researching cell-based approaches for corneal transplantation.
  • Dr. Christina Prescott is engaged in research relating to pediatric corneal surgery, to determine which surgical modifications and post-operative management strategies are most successful in pediatric corneal transplantation.

Ebola Eye Disease

  • Dr. Allen Eghrari is co-leading the PREVAIL III eye substudy, the largest Ebola eye study.

Fuchs Dystrophy 

  • Dr. Albert Jun is exploring the cellular causes and non-surgical treatments for Fuchs Corneal Dystrophy.
  • Dr. Allen Eghrari is researching the epidemiology of Fuchs Dystrophy and novel approaches to its treatment.

Global Eyebanking


  • Yassine Daoud, M.D. is exploring the pathology and psychology of keratoconus and age-related macular degeneration in order to develop new therapies.
  • Dr. Albert Jun, Dr. Shukti Chakravarti and Dr. Uri Soiberman are leading research of the cellular and genetic causes of keratoconus. Learn more about Dr. Chakravarti's lab.

Lasers in Eye Surgery

  • Dr. Yassine Daoud is exploring outcomes and additional uses of lasers in ocular surgery.

Ocular Surface Disease and Dry Eye

Surgical Education

  • Dr. Shameema Sikder is exploring the use of technology to improve surgical education, beginning with applications in cataract surgery and partial-thickness cornea transplant procedures (DMEK).

Tissue Engineering

  • Dr. Oliver Schein is developing cornea replacement tissue and related ocular materials through materials science and engineering approaches, such as leveraging stem cells, biomaterials and tissue-derived scaffolds to regenerate corneal endothelium. 

Technology in Ophthalmology

  • Dr. Allen Eghrari is focusing on mobile technology and ophthalmology (development of portable eye exams and validation of these mobile resources).


Cornea and Anterior Segment Research Faculty

Photo of Dr. Esen Akpek, M.D.

Akpek, Esen, M.D.

Professor of Ophthalmology
Associate Professor of Medicine
Bendann Family Professor of Ophthalmology
Director of Ocular Surface Disease and Dry Eye Clinic
Research Interests: Dry Eye, Artificial Cornea, Corneal Transplantation, Cataracts
Photo of Dr. Yassine Jamil Daoud, M.D.

Daoud, Yassine Jamil, M.D.

Assistant Professor of Ophthalmology
Chair of Ophthalmology. Howard County General Hospital
Research Interests: Femtosecond laser assisted cataract surgery, DSAEK corneal transplant, Secondary intraocular lens implant, Cataract surgery and uveitis, Outcome of DSAEK cornea transplant in complex cases
Photo of Dr. Allen Omid Eghrari, M.D., M.P.H.

Eghrari, Allen Omid, M.D., M.P.H.

Assistant Professor of Ophthalmology
Research Interests: Ebola Virus Disease, Fuchs Corneal Dystrophy, Cataract Surgery, Corneal Dystrophies
Photo of Dr. Albert Suk Jun, M.D., Ph.D.

Jun, Albert Suk, M.D., Ph.D.

Professor of Ophthalmology
Chief, Division of Cornea, Cataract and External Eye Diseases
Maurice E. Langham, Ph.D., Professor of Ophthalmology
Research Interests: Cataract Surgery, Corneal Genetics, Fuchs Endothelial Corneal Dystrophy, Granular Corneal Dystrophy, Keratoconus, Endothelial Keratoplasty, Lamellar Keratoplasty, Refractive Surgery
Photo of Dr. Christina Rapp Prescott, M.D., Ph.D.

Prescott, Christina Rapp, M.D., Ph.D.

Assistant Professor of Ophthalmology
Research Interests: Pediatric Corneal Surgery, Improving Patient Experience and Outcomes in Cataract Surgery
Photo of Dr. Oliver Douglas Schein, M.D., M.P.H.

Schein, Oliver Douglas, M.D., M.P.H.

Professor of Ophthalmology
Burton and Miriam Grossman Professor of Ophthalmology
Vice Chair for Quality and Safety, Wilmer Eye Institute
Research Interests: Epidemiology of major eye diseases, Assessment of ocular technology, Assessment of outcomes and complications of ocular surgery, Evidence-based improvement in quality and safety of ophthalmic care and surgery, Bioengineering of human corneal substitutes
Photo of Dr. Shameema Sikder, M.D.

Sikder, Shameema, M.D.

Associate Professor of Ophthalmology
Director, Center of Excellence for Ophthalmic Surgical Education and Training
Research Interests: Surgical Education, Keratoconus, Thyroid Eye Disease, Cataract Surgery, Granular Corneal Dystrophy
Photo of Dr. Uri Simcha Soiberman, M.D.

Soiberman, Uri Simcha, M.D.

Assistant Professor of Ophthalmology
Research Interests: keratoconus, applications of nanomedicine in the field of cornea, intraocular lenses, corneal transplants, corneal collagen cross-linking
Photo of Dr. Divya Srikumaran, M.D.

Srikumaran, Divya, M.D.

Assistant Professor of Ophthalmology
Chief, Wilmer Eye Institute - Odenton
Director, Ophthalmology Residency Program
Photo of Dr. Samuel Chi-Hung Yiu, M.D., M.S., Ph.D.

Yiu, Samuel Chi-Hung, M.D., M.S., Ph.D.

Associate Professor of Ophthalmology
Research Interests: Basic Research, Dry Eye, Lacrimal Gland Physiology, Nanodrug delivery
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