Research interests in the Eun Ji Shin Lab include clinical research on obesity and the effect on GI neoplasia/malignancy.

Research interests in the Marcia Canto Lab include pancreatic neoplasms, Barrett’s esophagus and endomicroscopy. We are also interested in the use of endoscopic ultrasound to identify early-stage pancreatic cancer and its precursors.

The GI Premalignant Disease and Biomarkers Laboratory studies gastrointestinal cancer and pre-cancer biogenesis and diagnostic biomarkers. The lab is led by Dr. Stephen Meltzer, who is known for his research in the molecular pathobiology of gastrointestinal malignancy and premalignancy. Research in the lab has led to several groundbreaking genomic, epigenomic and bioinformatic studies of esophageal and colonic neoplasms, shifting the gastrointestinal research paradigm toward genome-wide approaches. Biomarker panels have been devised that are currently at stages of clinical translation, with several in commercial development. In addition, this laboratory is developing three-dimensional models of gastric and esophageal early neoplasia based on organoids combined with CRISPR-Cas9 genome editing and other molecular methods. 

The GI Biomarkers Laboratory studies gastrointestinal cancer and pre-cancer biogenesis and biomarkers. The lab is led by Dr. Stephen Meltzer, who is known for his research in the molecular pathobiology of gastrointestinal malignancy and premalignancy. Research in the lab has led to several groundbreaking genomic, epigenomic and bioinformatic studies of esophageal and colonic neoplasms, shifting the gastrointestinal research paradaigm toward genome-wide approaches.