In the Stem Cell Biology program, investigators are studying the natural life cycle of human embryonic stem cells. They use human induced pluripotent stem cells (iPSCs) to understand disorders of blood-making organs, known as the hematopoietic system. Some current projects are using stem cells to study the development of pain and muscle disorders and trying to recreate pain nerve cells and muscle tissue in the lab to identify potential new drug candidates. Additional projects are working to generate a laboratory-made rat blood cell that could circulate in the body, delivering drug therapy, without forming tumors; seeking to understand the role of immune cells in the brain; and trying to develop a “mini-brain” in the lab to serve as a disease model to study neurodegeneration.
The Stem Cell Biology Program at Johns Hopkins’ Institute for Cell Engineering
Researcher Hongjun Song introduces the Stem Cell Biology Program, where scientists get an up-close look at diseases by making stem cells with patients' DNA and growing affected cell types in the lab. Others are working on ways to make blood for transfusions or seeing how mental illness relates to problems in early brain development.
Professor of Neuroscience
Professor of Physiology
Director, Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering,
Associate Professor of Neuroscience
Assistant Professor of Pediatrics