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Provide early detection, prognosis, and/or predicting response to available medications; develop new blood tests to better monitor treatment response; and, using blood-derived stem cells, test whether patients will be helped by emerging medication treatments.


Translate research into clinical care by defining patients who respond optimally to currently available and emerging therapies. Identify new therapeutic targets based on refined and granular understanding of disease mechanisms.


Alzheimer's and Dementia Research

Questions we're asking that inform us on how to best care for patients include:

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Big Data Power

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Scaling Evidence-Based Care

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Expedite Discovery - Closing the Loop

How can we fast track the research from clinic to test tube and back to the clinic with biomarkers for subtyping and for advancing therapeutics?

Innovation: Brain Scans

Innovation: New Blood Test

Can novel blood tests based on “exosomes” be used to learn about what’s going on in the brain so as to stage the AD brain disease and monitor treatment response?

Innovation: Stem Cell Models

Can blood derived stems cells be used to test whether individual patients will be helped by available and emerging medication treatments?

Clinical Trials

The Richman Family Precision Medicine Center of Excellence in Alzheimer’s Disease can facilitate access to several clinical trials conducted as part of the Johns Hopkins Memory and Alzheimer's Treatment Center (MATC) or the NIA-funded Johns Hopkins Alzheimer's Disease Research Center (ADRC).


Patient Care for Alzheimer's Disease 

The research we do directly impacts the treatment options available to our patients. Find out more about patient care for Alzheimer's Disease.

The Johns Hopkins Memory and Alzheimer's Treatment Center
The Johns Hopkins Bayview Medical Center
5300 Alpha Commons Drive, Floor 4
Baltimore, MD 21224



Faculty Spotlight

Dimitrios Kapogiannis, M.D.

Dimitrios Kapogiannis, M.D. is Chief of the Human Neuroscience Unit at the National Institute of Aging and adjunct Associate Professor in the Department of Neurology at Johns Hopkins. He is a clinician-scientist, ABPN-certified in Neurology and UCNS-certified in Behavioral Neurology. His translational laboratory focuses on discovering novel biomarkers for preclinical diagnosis and therapeutic response in Alzheimer's and other neurodegenerative diseases. He has pioneered deriving Extracellular Vesicles enriched for neuronal and astrocytic origin from peripheral blood.

Meet Dr. Kapogiannis

Charitable Giving

Support diagnosis and treatment advancements and discoveries by Johns Hopkins scientists.

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