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Gynecology & Obstetrics

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Conditions We Treat: BRCA1 and BRCA 2 Gene Mutations

Everyone has BRCA1 and BRCA2 genes. Harmful changes (mutations) in one or both of these genes can increase a woman’s risk of developing both breast and ovarian cancers, and in some cases fallopian tube and/or peritoneal cancers. If you have mutations in either of these genes, there are preventive treatment options available to help you reduce your risk.

BRCA1 and BRCA2 Genes: What You Need to Know

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  • Everyone has BRCA1 and BRCA2 genes. These are important genes that help repair damaged DNA.
  • Harmful changes (mutations) in one or both of these genes may increase a woman’s chances of developing breast and ovarian cancer, and in some cases fallopian and/or peritoneal cancer.
  • BRCA1 and BRCA2 gene mutations are hereditary and can be passed on to both males and females. 
  • Genetic testing can reveal BRCA1 and BRCA 2 mutations. If genetic testing determines the presence of BRCA1 and/or BRCA 2 gene mutations, a woman, along with the help of her doctor, can take steps to manage her risk of developing cancer.
  • If you are considering undergoing genetic testing, you should first make an appointment with a genetic counselor and a gynecologic oncologist.

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Why choose Johns Hopkins for management of BRCA1 and BRCA2 gene mutations?

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Our Treatments

The Johns Hopkins Kelly Gynecologic Oncology Service is a leader in fertility-sparing surgery and chemoprevention therapies. Our patients have faster recovery times and better overall outcomes. 

Dr. Fader with a patient

Our Patient Care

We believe in treating the whole patient — body, mind and spirit. “We are by your side every step of the way — whether you are just beginning treatment or have completed treatment and are undergoing survivorship care.” – Amanda Fader, M.D.

As part of your care, we offer a range of fertility preservation services.