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Researchers at Johns Hopkins are constantly advancing science through basic, translational and clinical investigations. Here are highlights of our most current findings.
Using CRISPR-Cas9, a revolutionary gene-editing technique, Seydoux can delete, replace, or reprogram a nematode gene at will—and then step back and observe the result.
Understanding Ubiquitin
Johns Hopkins biophysicist Cynthia Wolberger explains how the small protein ubiquitin regulates many events in the cell, including turning genes off and on.
Epigenetics: A Symphony of Discovery
Johns Hopkins Kimmel Cancer Center Director, Bill Nelson, M.D., Ph.D., discusses epigenetics using musicians from the Peabody Institute.
Johns Hopkins researchers report the unexpected presence of a type of neuron in the brains of mice that appears to play a central role in promoting sleep by turning ‘off’ wake-promoting neurons. The newly identified brain cells, located in a part of the hypothalamus called the zona incerta, they say, could offer novel drug targets to treat sleep disorders, such as insomnia and narcolepsy, caused by the dysfunction of sleep-regulating neurons.
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