Select list of our latest publications from our lab by topic (Lab members in bold):

For a complete and always up-to-date list of publications, please visit PubMed.

Neuroprognostication

de Oliveira Manoel AL, Muehlschlegel S. Ethical Challenges, Treatment Decisions, and Research Outcomes in Neurocritical Care. Neurocrit Care. 2026 Jun;44(3):778-784. doi: 10.1007/s12028-026-02480-9. Epub 2026 Mar 13.PMID: 41826778 

Hu EXY, van Hoorn ES, Retel Helmrich IRA, Muehlschlegel S, Rietjens JAC, Lingsma HF. Facilitators and Barriers of the Use of Prognostic Models for Clinical Decision Making in Acute Neurologic Care: A Systematic Review. Med Decis Making. 2025 Aug;45(6):753-770. doi: 10.1177/0272989X251343027. Epub 2025 Jun 29.PMID: 40581849 

Meurer KJ, Presciutti AM, Bannon SM, Kubota R, Baskaran N, Kim J, Zhang Q, Reichman M, Fishbein NS, Lichstein K, Motta M, Muehlschlegel S, Reznik ME, Jaffa MN, Creutzfeldt CJ, Fehnel CR, Tomlinson AD, Williamson CA, Vranceanu AM, Hwang DY; COMA-F Investigators. Characterizing Stressors and Coping Strategies Among Caregivers of Patients with Severe Acute Brain Injury by Level of Distress. Neurocrit Care. 2026 Feb;44(1):95-104. doi: 10.1007/s12028-025-02294-1. Epub 2025 Jun 6.PMID: 40481284 

Muehlschlegel S. Prognostication in Neurocritical Care. Continuum (Minneap Minn). 2024 Jun 1;30(3):878-903. doi: 10.1212/CON.0000000000001433. PMID: 38830074.

Goss A, Ge C, Crawford S, Goostrey K, Buddadhumaruk P, Hough CL, Lo B, Carson S, Steingrub J, White DB, Muehlschlegel S. Prognostic Language in Critical Neurologic Illness: A Multicenter Mixed-Methods Study. Neurology. 2023 Aug 1;101(5):e558-e569. doi: 10.1212/WNL.0000000000207462. Epub 2023 Jun 8. PMID: 37290972; PMCID: PMC10401677.

Fleming V, Muehlschlegel S. Neuroprognostication. Crit Care Clin. 2023 Jan;39(1):139-152. doi: 10.1016/j.ccc.2022.06.005. Epub 2022 Oct 13. PMID: 36333028.

Goostrey K, Muehlschlegel S. Prognostication and shared decision making in neurocritical care. BMJ. 2022 Apr 7;377:e060154. doi: 10.1136/bmj-2021-060154. PMID: 35696329.

Ge C, Goss AL, Crawford S, Goostrey K, Buddadhumaruk P, Shields AM, Hough CL, Lo B, Carson SS, Steingrub J, White DB, Muehlschlegel S. Variability of Prognostic Communication in Critically Ill Neurologic Patients: A Pilot Multicenter Mixed-Methods Study. Crit Care Explor. 2022 Feb 21;4(2):e0640. doi: 10.1097/CCE.0000000000000640. PMID: 35224505; PMCID: PMC8863127.

Jones K, Quinn T, Mazor KM, Muehlschlegel S. Prognostic Uncertainty in Critically Ill Patients with Traumatic Brain Injury: A Multicenter Qualitative Study. Neurocrit Care. 2021 Oct;35(2):311-321. doi: 10.1007/s12028-021-01230-3. Epub 2021 Jun 2. PMID: 34080083.

Shared Decision Making

Liu WL, Zhang L, Djamasbi S, Tulu B, Muehlschlegel S. Development of web- and mobile-based shared decision-making tools in the neurological intensive care unit. Neurotherapeutics. 2025 Jan;22(1):e00503. doi: 10.1016/j.neurot.2024.e00503. Epub 2024 Dec 6.PMID: 39643583 

Fleming V, Prasad A, Ge C, Crawford S, Meraj S, Hough CL, Lo B, Carson SS, Steingrub J, White DB, Muehlschlegel S. Prevalence and predictors of shared decision-making in goals-of-care clinician-family meetings for critically ill neurologic patients: a multi-center mixed-methods study. Crit Care. 2023 Oct 21;27(1):403. doi: 10.1186/s13054-023-04693-2. PMID: 37865797; PMCID: PMC10590503.

Muehlschlegel S, Goostrey K, Flahive J, Zhang Q, Pach JJ, Hwang DY. Pilot Randomized Clinical Trial of a Goals-of-Care Decision Aid for Surrogates of Patients With Severe Acute Brain Injury. Neurology. 2022 Oct 3;99(14):e1446-e1455. doi: 10.1212/WNL.0000000000200937. PMID: 35853748; PMCID: PMC9576301.

Muehlschlegel S, Perman SM, Elmer J, Haggins A, Teixeira Bailey ND, Huang J, Jansky L, Kirchner J, Kasperek-Wynn R, Lipman PD, Yeatts SD, Fetters MD, Dickert NW, Silbergleit R. The Experiences and Needs of Families of Comatose Patients After Cardiac Arrest and Severe Neurotrauma: The Perspectives of National Key Stakeholders During a National Institutes of Health-Funded Workshop. Crit Care Explor. 2022 Mar 4;4(3):e0648. doi: 10.1097/CCE.0000000000000648. PMID: 35265851; PMCID: PMC8901216.

Muehlschlegel S, Hwang DY, Flahive J, Quinn T, Lee C, Moskowitz J, Goostrey K, Jones K, Pach JJ, Knies AK, Shutter L, Goldberg R, Mazor KM. Goals-of-care decision aid for critically ill patients with TBI: Development and feasibility testing. Neurology. 2020 Jul 14;95(2):e179-e193. doi: 10.1212/WNL.0000000000009770. Epub 2020 Jun 17. PMID: 32554766; PMCID: PMC7455326. 

Guidelines, White Papers, and Editorials

Mainali S, Fontaine GV, Rajajee V, Montellano FA, Muehlschlegel S, Wartenberg KE, Alexander SA, Busl KM, Hocker SE, Hwang DY, Kim KS, Madzar D, Mahanes D, Meixensberger J, Sakowitz OW, Varelas PN, Weimar C, Westermaier T, Creutzfeldt CJ. Guidelines for Neuroprognostication in Critically ill Adults with Acute Ischemic Stroke. Neurocrit Care. 2026 Jun;44(3):745-769. doi: 10.1007/s12028-026-02486-3. Epub 2026 Apr 6.PMID: 41942818 

Madzar D, Rajajee V, Muehlschlegel S, Wartenberg KE, Alexander SA, Busl KM, Creutzfeldt CJ, Fontaine GV, Hwang DY, Kim KS, Mahanes D, Mainali S, Meixensberger J, Sakowitz OW, Varelas PN, Weimar C, Westermaier T, Hocker SE. Guidelines for Neuroprognostication in Critically Ill Adults with Status Epilepticus. Neurocrit Care. 2026 Apr;44(2):365-383. doi: 10.1007/s12028-025-02425-8. Epub 2026 Jan 8.PMID: 41507670

Marshall MF, Davis FD, Fogelman PA, Oczkowski S, Reid JC, Arellano D, Aslakson RA, Campbell J, Courtright K, Egressy K, Epstein E, Green E, Hua M, John PR, Kross EK, Martin ND, Melo BA, Muehlschlegel S, Perez-Protto S, Roberts B, Shalev D, Wescoe Singley J, Strickland SL, Korzick KA. Society of Critical Care Medicine Clinical Practice Guidelines on Adult End-of-Life Care in the ICU. Crit Care Med. 2025 Dec 1;53(12):e2734-e2746. doi: 10.1097/CCM.0000000000006856. Epub 2025 Dec 2.PMID: 41342842 

Hauschildt KE, Muehlschlegel S. Tackling Ableism After Critical Illness Is Overdue. Crit Care Med. 2025 Feb 26. doi: 10.1097/CCM.0000000000006625. Epub ahead of print. PMID: 40009032.

Lau WK, Fehnel CR, Macchi ZA, Mehta AK, Auffret M, Bogetz JF, Fleisher JE, Graber JJ, Leeper HE, Manglani-Terranova HR, Muehlschlegel S, Mroz EL, Pedowitz EJ, Ramanathan U, Sarmet M, Shlobin NA, Sokol L, Weeks SA, Xu J, Bundy Medsger H, Creutzfeldt CJ, Vranceanu AM, Zahuranec DB, Hwang DY. Research Priorities in Neuropalliative Care: A Consensus Statement From the International Neuropalliative Care Society. JAMA Neurol. 2025 Feb 3. doi: 10.1001/jamaneurol.2024.4932. Epub ahead of print. PMID: 39899319.

Quinlan M, Muehlschlegel S. Flipping the Script: Early Neurological Gains May Redefine Recovery Prognostication After Intracerebral Hemorrhage. Stroke. 2025 Mar;56(3):628-630. doi: 10.1161/STROKEAHA.124.050306. Epub 2025 Feb 3. PMID: 39895500; PMCID: PMC11850180.

Depreitere B, Becker C, Ganau M, Gardner RC, Younsi A, Lagares A, Marklund N, Metaxa V, Muehlschlegel S, Newcombe VFJ, Prisco L, van der Jagt M, van der Naalt J. Unique considerations in the assessment and management of traumatic brain injury in older adults. Lancet Neurol. 2025 Feb;24(2):152-165. doi: 10.1016/S1474-4422(24)00454-X. PMID: 39862883. 

Bhende BU, Muehlschlegel S. Echoes of the past: does prior TBI shape future TBI outcomes? Trauma Surg Acute Care Open. 2024 Aug 14;9(1):e001569. doi: 10.1136/tsaco-2024-001569. PMID: 39171082; PMCID: PMC11337666.

Muehlschlegel S, Rajajee V, Wartenberg KE, Alexander SA, Busl KM, Creutzfeldt CJ, Fontaine GV, Hocker SE, Hwang DY, Kim KS, Madzar D, Mahanes D, Mainali S, Meixensberger J, Sakowitz OW, Varelas PN, Weimar C, Westermaier T. Guidelines for Neuroprognostication in Critically Ill Adults with Moderate-Severe Traumatic Brain Injury. Neurocrit Care. 2024 Apr;40(2):448-476. doi: 10.1007/s12028-023-01902-2. Epub 2024 Feb 17. PMID: 38366277; PMCID: PMC10959796.

Jaffa MN, Kirsch HL, Creutzfeldt CJ, Guanci M, Hwang DY, LeTavec D, Mahanes D, Natarajan G, Steinberg A, Zahuranec DB, Muehlschlegel S; Curing Coma Campaign Collaborators. Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Goals-of-Care and Family/Surrogate Decision-Maker Data. Neurocrit Care. 2023 Dec;39(3):600-610. doi: 10.1007/s12028-023-01796-0. Epub 2023 Sep 13. Erratum in: Neurocrit Care. 2024 Oct 15. doi: 10.1007/s12028-024-02098-9. PMID: 37704937.