In This Section      
 

MOUTH Study

(Men Offering Understanding of Throat HPV)
IRB: JH IRB00119537

A Research Study of Oral HPV in Healthy Men

man for MOUTH study

Researchers at Johns Hopkins want to better understand how certain behaviors, such as smoking, and other risk factors affect oral HPV infection rates and how likely these infections will persist over time. While there is no approved screening for oral HPV infection or oropharynx cancer, we are evaluating promising HPV markers that may help identify people at risk of oropharyngeal cancer earlier.

What is Oral Human Papillomavirus (HPV)?

HPV is a sexually transmitted infection. HPV can be transmitted to the mouth or throat during oral sex. Oral HPV infection can lead to cancers of the oropharynx (tonsil, back of tongue).

Who Can Join?

You may be able to join this study if you are:

  • Male 30 and older
  • Have performed oral sex
  • Have never had head or neck cancer
  • Men and women with history of anal or genital dysplasia or cancer
  • Partners of patients with HPV-related cancer (head and neck, genital or anal)
  • Willing to return to Johns Hopkins if the researchers find that you are HPV positive

Take this brief survey to see if you are eligible to participate. 

What Does the Study Involve?

If you enroll, you will:

  • Take a brief online survey
  • Provide samples (oral rinse, urine, and small blood sample) to test for HPV
  • Receive a $15 gift card for the first study visit and a $25 gift card for each follow up visit

How Long Will the Study Last?

  • People without HPV will have only 1 study visit
  • People with HPV will have 4 more annual study visits

Contact Us!

Email: MOUTHstudy@jhu.edu
Call us: 443-287-8754
Click here to see if you are eligible.

Why Oral Cancer Threatens Men: researchers wrestle with rising rates of throat cancers (Scientific American, Nov. 2018)

More information about HPV

View a webinar featuring Drs. D'Souza and Fakhry (The Public Health Foundation (PHF), Feb. 13, 2019)

Head and neck cancer on the rise (WYPR, Jan. 10, 2017)

***This research study is supported by funding from the National Institutes of Health’s National Institute of Dental and Craniofacial Research. R35 DE026631

Principal Investigator: Dr. Gypsyamber D'Souza
JH SOM eIRB#: IRB00119537