BRAF Brain Tumor Center

The Johns Hopkins BRAF Brain Tumor Center aims to help patients with brain tumors that originated in the brain (primary brain tumors) that have a BRAF gene mutation. Our multispecialty team includes experts across neurosurgery and the Johns Hopkins Kimmel Cancer Center who provide patient care and conduct research to improve outcomes for patients with these rare tumors.

What We Do

Evaluate and treat patients with BRAF-mutated primary brain tumors.

Explore the role of new pathway inhibitors that might help treat these patients.

Partner with our basic science colleagues to discover mechanisms of resistance, clinically relevant targets and new pathway-specific drugs.

BRAF Brain Tumor Specialists

Advanced Practitioners

Christie Adams, PA-C

Physician Assistant working with Chetan Bettegowda, M.D., Ph.D.

Christie Adams

Jill Anderson, PA-C

Physician Assistant Manager working with Henry Brem, M.D.

Jill Anderson

Ashley Kang, PA-C

Physician Assistant working with Debraj Mukherjee, M.D., M.P.H.

Ashley Kang

Carla Scott, PA-C

Senior Physician Assistant working with Chris Jackson, M.D., and Judy Huang, M.D.


Glioblastoma and BRAF Gene Mutation | Courtney’s Story

After being diagnosed with a glioblastoma brain tumor in 2008, Courtney’s prognosis was not good. A referral to neuro-oncologist Karisa Schreck and neurosurgeon Jon Weingart changed the course of her illness. They identified the tumor as having a specific mutation in the BRAF gene, and they used a combination of surgery, conventional chemoradiation and targeted therapy to reduce its size and then keep the cancer in remission.