Linzhao Cheng, Ph.D.
The Cheng lab studies human stem cell biology and engineering to develop experimental models of and treatments for human blood diseases. The team has made several discoveries in understanding human stem cell self-renewal and hematopoietic (blood-forming) differentiation using adult hematopoietic stem cells and human pluripotent stem cells. Recently, they pioneered efficient methods to establish human induced pluripotent stem (iPS) cells from both blood cells and fibroblasts by using plasmids that don't integrate into chromosomes. In an effort to develop better genetic models and gene therapy methods, the Cheng lab develops new methods for making genetic modifications in human cells using various methods such as human genome editing.
Meet Dr. Cheng
On making stem cells from a patient's blood sample:
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Professor of Medicine, Division of Hematology
View a list of publications on PubMed.