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Jonathan Schneck, M.D., Ph.D.

Research Summary

Jonathan Schneck, M.D., Ph.D.
Jonathan Schneck, M.D., Ph.D.

The Schneck lab studies the biophysical, genetic and environmental control of the T cell receptor. The research team has developed an acellular aAPC, a lego-like system that can be used to study T cells responses at a variety of different levels. Currently aAPC are being used to study manipulation of in vivo CTL responses and hold potential as a therapeutic approaches to augment both adoptive and active immunotherapy.

The team also develops approaches to understanding genetic regulation of glycosylation, among the most complex post-translational modifications with an extremely high level of diversity that has made it refractory to high-throughput analyses. One approach developed is a lectin microarray for defining mammalian cell surface glycan signatures and analyzing diverse cell processes including cell development and differentiation, cell-cell communication, pathogen-host recognition, and cell surface biomarker identification. On-going studies further explore use of this new technology in the identification of novel biomarkers.

Additional information

Meet Dr. Schneck

On creating an artificial conductor to direct the immune system symphony:

Titles
Professor of Pathology 

Graduate programs
Immunology  
Pathobiology
Cellular and Molecular Medicine 

Publications
View a list of publications on PubMed.

Contact information
Phone: 410-614-4589
Email: jschnec1@jhmi.edu
Website: http://pathology2.jhu.edu/schnecklab/

 
 
 

 

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