Web notes  

July 2020

Pediatrics Archives

1. Axelsson Raja A, Farhad H, Valente AM, Couce JP, Jefferies JL, Bundgaard H, Zahka K, Lever H, Murphy AM, Ashley E, Day SM, Sherrid MV, Shi L, Bluemke DA, Canter CE, Colan SD, Ho CY. Prevalence and progression of late gadolinium enhancement in children and adolescents with hypertrophic cardiomyopathy. Circulation. 2018 Apr 5. pii: CIRCULATIONAHA.117.032966. doi: 10.1161/CIRCULATIONAHA.117.032966. [Epub ahead of print]
Key words: delayed enhancement; fibrosis; magnetic resonance imaging; pediatric; sarcomere mutation carriers; subclinical

2. Carrasco M, Perin J, Jennings JM, Parkinson C, Gilmore MM, Chavez-Valdez R, Massaro AN, Koehler RC, Northington FJ, Tekes A, Lee JK. Cerebral autoregulation and conventional and diffusion tensor imaging magnetic resonance imaging in neonatal hypoxic-ischemic encephalopathy. Pediatr Neurol. 2018 Apr 2. pii: S0887-8994(17)31137-2. doi: 10.1016/j.pediatrneurol.2018.02.004. [Epub ahead of print]
Key words: Blood pressure; Brain hypoxia ischemia; Cerebrovascular circulation; Magnetic resonance imaging; Newborn

3. Dam KH, Kaufman MR, Patel EU, Van Lith LM, Hatzold K, Marcell AV, Mavhu W, Kahabuka C, Mahlasela L, Njeuhmeli E, Seifert Ahanda K, Ncube G, Lija G, Bonnecwe C, Tobian AAR. Parental communication, engagement, and support during the adolescent voluntary medical male circumcision experience.
Clin Infect Dis. 2018 Apr 3;66(suppl_3):S189-S197. doi: 10.1093/cid/cix970.
Key words: male circumcision, adolescent, parental communication

4. Jouroukhin Y, Kageyama Y, Misheneva V, Shevelkin A, Andrabi S, Prandovszky E, Yolken RH, Dawson VL, Dawson TM, Aja S, Sesaki H, Pletnikov MV. DISC1 regulates lactate metabolism in astrocytes: implications for psychiatric disorders. Transl Psychiatry. 2018 Apr 12;8(1):76. doi: 10.1038/s41398-018-0123-9.
Key words: DISC1, lactate metabolism, astrocytes, psychiatric disorders

5. Kaufman MR, Dam KH, Sharma K, Van Lith LM, Hatzold K, Marcell AV, Mavhu W, Kahabuka C, Mahlasela L, Patel EU, Njeuhmeli E, Seifert Ahanda K, Ncube G, Lija G, Bonnecwe C, Tobian AAR. Females' peer influence and support for adolescent males receiving voluntary medical male circumcision services.
Clin Infect Dis. 2018 Apr 3;66(suppl_3):S183-S188. doi: 10.1093/cid/cix1057.
Key words: adolescent males, male circumcision, peer influence

6. Kaufman MR, Patel EU, Dam KH, Packman ZR, Van Lith LM, Hatzold K, Marcell AV, Mavhu W, Kahabuka C, Mahlasela L, Njeuhmeli E, Seifert Ahanda K, Ncube G, Lija G, Bonnecwe C, Tobian AAR. Counseling received by adolescents undergoing voluntary medical male circumcision: moving toward age-equitable comprehensive human immunodeficiency virus prevention measures. Clin Infect Dis. 2018 Apr 3;66(suppl_3):S213-S220. doi: 10.1093/cid/cix952.
Key words: male circumcision, adolescent males, HIV, HIV prevention

7. Kaufman MR, Patel EU, Dam KH, Packman ZR, Van Lith LM, Hatzold K, Marcell AV, Mavhu W, Kahabuka C, Mahlasela L, Njeuhmeli E, Seifert Ahanda K, Ncube G, Lija G, Bonnecwe C, Tobian AAR. Impact of counseling received by adolescents undergoing voluntary medical male circumcision on knowledge and sexual intentions. Clin Infect Dis. 2018 Apr 3;66(suppl_3):S221-S228. doi: 10.1093/cid/cix973.
Key words: male circumcision, adolescent males, HIV, HIV prevention

8. Kinsella JP, Steinhorn RH, Mullen MP, Hopper RK, Keller RL, Ivy DD, Austin ED, Krishnan US, Rosenzweig EB, Fineman JR, Everett AD, Hanna BD, Humpl T, Raj JU, Abman SH; Pediatric Pulmonary Hypertension Network (PPHNet). The left ventricle in congenital diaphragmatic hernia: implications for the management of pulmonary hypertension. J Pediatr. 2018 Apr 5. pii: S0022-3476(18)30287-7. doi: 10.1016/j.jpeds.2018.02.040. [Epub ahead of print] No abstract available.
Key words: congenital diaphragmatic hernia, pulmonary hypertension, left ventricle

9. Ladd MR, Martin LY, Werts A, Costello C, Sodhi C, Fulton W, March JC, Hackam D. The development of newborn porcine models for evaluation of tissue engineered small intestine. Tissue Eng Part C Methods. 2018 Apr 11. doi: 10.1089/ten.TEC.2018.0040. [Epub ahead of print]
Key words: newborn porcine models; porcine model; tissue-engineered small intestine

10. Mavhu W, Hatzold K, Dam KH, Kaufman MR, Patel EU, Van Lith LM, Kahabuka C, Marcell AV, Mahlasela L, Njeuhmeli E, Seifert Ahanda K, Ncube G, Lija G, Bonnecwe C, Tobian AAR. Adolescent wound-care self-efficacy and practices after voluntary medical male circumcision-a multicountry assessment. Clin Infect Dis. 2018 Apr 3;66(suppl_3):S229-S235. doi: 10.1093/cid/cix953.
Key words: adolescents, wound care, male circumcision

11. Patel EU, Kaufman MR, Dam KH, Van Lith LM, Hatzold K, Marcell AV, Mavhu W, Kahabuka C, Mahlasela L, Njeuhmeli E, Seifert Ahanda K, Ncube G, Lija G, Bonnecwe C, Tobian AAR. Age differences in perceptions of and motivations for voluntary medical male circumcision among adolescents in South Africa, Tanzania, and Zimbabwe. Clin Infect Dis. 2018 Apr 3;66(suppl_3):S173-S182. doi: 10.1093/cid/cix951.
Key words: male circumcision, adolescents, Africa

12. Selamet Tierney ES, Levine JC, Sleeper LA, Roman MJ, Bradley TJ, Colan SD, Chen S, Campbell MJ, Cohen MS, De Backer J, Heydarian H, Hoskoppal A, Lai WW, Liou A, Marcus E, Nutting A, Olson AK, Parra DA, Pearson GD, Pierpont ME, Printz BF, Pyeritz RE, Ravekes W, Sharkey AM, Srivastava S, Young L, Lacro RV; Pediatric Heart Network Investigators. Influence of aortic stiffness on aortic-root growth rate and outcome in patients with the Marfan syndrome. Am J Cardiol. 2018 Feb 13. pii: S0002-9149(18)30158-9. doi: 10.1016/j.amjcard.2018.01.016. [Epub ahead of print]
Key words: aortic root, Marfan syndrome

13. Simner PJ, Antar AAR, Hao S, Gurtowski J, Tamma PD, Rock C, Opene BNA, Tekle T, Carroll KC, Schatz MC, Timp W. Antibiotic pressure on the acquisition and loss of antibiotic resistance genes in Klebsiella pneumoniae. J Antimicrob Chemother. 2018 Apr 10. doi: 10.1093/jac/dky121. [Epub ahead of print]
Key words: antibiotic pressure, antibiotic resistance, Klebisella

14. Tobian AAR, Dam KH, Van Lith LM, Hatzold K, Marcell AV, Mavhu W, Kahabuka C, Mahlasela L, Patel EU, Njeuhmeli E, Seifert Ahanda K, Ncube G, Lija G, Bonnecwe C, Kaufman MR. Providers' perceptions and training needs for counseling adolescents undergoing voluntary medical male circumcision.
Clin Infect Dis. 2018 Apr 3;66(suppl_3):S198-S204. doi: 10.1093/cid/cix1036.
Key words: providers, adolescents, male circumcision

15. Tchou MJ, Tang Girdwood S, Wormser B, Poole M, Davis-Rodriguez S, Caldwell JT, Shannon L, Hagedorn PA, Biondi E, Simmons J, Anderson J, Brady PW. Reducing electrolyte testing in hospitalized children by using quality improvement methods. Pediatrics. 2018 Apr 4. pii: e20173187. doi: 10.1542/peds.2017-3187. [Epub ahead of print]
Key words: electrolyte testing, pediatric patients, quality improvement

16. Van Lith LM, Mallalieu EC, Patel EU, Dam KH, Kaufman MR, Hatzold K, Marcell AV, Mavhu W, Kahabuka C, Mahlasela L, Njeuhmeli E, Seifert Ahanda K, Ncube G, Lija G, Bonnecwe C, Tobian AAR. Perceived quality of in-service communication and counseling among adolescents undergoing voluntary medical male circumcision. Clin Infect Dis. 2018 Apr 3;66(suppl_3):S205-S212. doi: 10.1093/cid/cix971.
Key words: in-service communication, male circumcision, adolescents

1. Brady TM, Stefani-Glücksberg A, Simonetti GD. Management of high blood pressure in children: similarities and differences between US and European guidelines. Pediatr Nephrol. 2018 Mar 28. doi: 10.1007/s00467-018-3946-y. [Epub ahead of print]
Key words: high blood pressure, pediatrics, management

2. Brown CE, Kong T, Bordón C, Yolken R, Jones-Brando L, McNulty J. One-pot, multicomponent synthesis of 2,3-disubstituted quinazolin-ones with potent and selective activity against Toxoplasma gondii.
Bioorg Med Chem Lett. 2018 Mar 16. pii: S0960-894X(18)30229-4. doi: 10.1016/j.bmcl.2018.03.036. [Epub ahead of print]
Key words: Multi-component synthesis; Quinazolinone; Toxoplasma gondii; Toxoplasmosis

3. Canan CE, Chander G, Monroe AK, Gebo KA, Moore RD, Agwu AL, Alexander GC, Lau B. High-risk prescription opioid use among people living with HIV. J Acquir Immune Defic Syndr. 2018 Mar 27. doi: 10.1097/QAI.0000000000001690. [Epub ahead of print]
Key words: opioid, HIV, high-risk use

4. Doernberg SB, Abbo LM, Burdette SD, Fishman NO, Goodman EL, Kravitz GR, Leggett JE, Moehring RW, Newland JG, Robinson PA, Spivak ES, Tamma PD, Chambers HF. Essential resources and strategies for antibiotic stewardship programs in the acute care setting. Clin Infect Dis. 2018 Mar 26. doi: 10.1093/cid/ciy255. [Epub ahead of print]
Key words: antibiotics, acute care, stewardship

5. Goldstein SD, Beaulieu RJ, Niño DF, Chun Y, Banerjee A, Sodhi CP, Hackam DJ. Early detection of necrotizing enterocolitis using broadband optical spectroscopy. J Pediatr Surg. 2018 Mar 7. pii: S0022-3468(18)30168-4. doi: 10.1016/j.jpedsurg.2018.02.083. [Epub ahead of print]
Key words: Hyperspectral imaging; Necrotizing enterocolitis; Prematurity

6. Gutierrez MJ, Sullivan KE, Fuleihan R; USIDNET Consortium, Bingham CO 3rd. Phenotypic characterization of patients with rheumatologic manifestations of common variable immunodeficiency.
Semin Arthritis Rheum. 2018 Feb 23. pii: S0049-0172(17)30654-6. doi: 0.1016/j.semarthrit.2018.02.013. [Epub ahead of print]
Key words: Autoimmunity; CVID; Primary Antibody Deficiency; Rheumatologic Disease

7. Matson PA, Fortenberry JD, Chung SE, Gaydos CA, Ellen JM. Weekly variations in feelings of trust predict incident STI within a prospective cohort of adolescent women from a US city. Sex Transm Infect. 2018 Mar 24. pii: sextrans-2017-053431. doi: 10.1136/sextrans-2017-053431. [Epub ahead of print]
Key words: adolescent; chlamydia trachomatis; neisseria gonorrhoea; sexual behaviour; sexual health

8. McClory SP, Lynch KW, Ling JP. HnRNP L represses cryptic exons. RNA. 2018 Mar 26. pii: rna.065508.117. doi: 10.1261/rna.065508.117. [Epub ahead of print]
Key words: Alternative Splicing; Cryptic Exons; Dinucleotide Repeats; HNRNPL; HnRNP L

9. Panjwani N, Xiao B, Xu L, Gong J, Keenan K, Lin F, He G, Baskurt Z, Kim S, Zhang L, Esmaeili M, Blackman S, Scherer SW, Corvol H, Drumm M, Knowles M, Cutting G, Rommens JM, Sun L, Strug LJ. Improving imputation in disease-relevant regions: lessons from cystic fibrosis. NPJ Genom Med. 2018 Mar 20;3:8. doi: 10.1038/s41525-018-0047-6. eCollection 2018.
Key words: cystic fibrosis, genotype imputation

10. Parks S, Avramopoulos D, Mulle J, McGrath J, Wang R, Goes FS, Conneely K, Ruczinski I, Yolken R, Pulver AE, Pearce BD. HLA typing using genome wide data reveals susceptibility types for infections in a psychiatric disease enriched sample. Brain Behav Immun. 2018 Mar 21. pii: S0889-1591(18)30045-X. doi: 10.1016/j.bbi.2018.03.001. [Epub ahead of print]
Key words: Bipolar disorder; Herpes virus; Histocompatibility antigen; Major histocompatibility complex; Schizophrenia; Toxoplasma

11. Rice JL, Diette GB, Suarez-Cuervo C, Brigham EP, Lin SY, Ramanathan M Jr, Robinson KA, Azar A. Allergen-specific immunotherapy in the treatment of pediatric asthma: a systematic review.
Pediatrics. 2018 Mar 23. pii: e20173833. doi: 10.1542/peds.2017-3833. [Epub ahead of print] Review.
Key words: allergen, pediatrics, asthma, immunotherapy

12. Shilkofski N, Crichlow A, Rice J, Cope L, Kyaw YM, Mon T, Kiguli S, Jung J. A standardized needs assessment tool to inform the curriculum development process for pediatric resuscitation simulation-based education in resource-limited settings. Front Pediatr. 2018 Feb 28;6:37. doi: 10.3389/fped.2018.00037. eCollection 2018.
Key words: PIPES tool; developing countries; limited-resource settings; needs assessment; neonatal resuscitation; pediatric critical care; pediatric resuscitation; simulation-based training

13. Tamma PD, Fan Y, Bergman Y, Sick-Samuels AC, Hsu AJ, Timp W, Simner PJ, Prokesch BC, Greenberg DE. Successful treatment of persistent Burkholderia cepacia complex bacteremia with ceftazidime-avibactam. Antimicrob Agents Chemother. 2018 Mar 27;62(4). pii: e02213-17. doi: 10.1128/AAC.02213-17. Print 2018 Apr.
Key words: Burkholderia cepacia complex; bacteremia; ceftazidime-avibactam; whole-genome sequencing

14. Trent M, Coleman JS, Hardick J, Perin J, Tabacco L, Huettner S, Ronda J, Felter-Wernsdorfer R, Gaydos CA. Clinical and sexual risk correlates of <i>Mycoplasma genitalium</i> in urban pregnant and non-pregnant young women: cross-sectional outcomes using the baseline data from the Women's BioHealth Study. Sex Transm Infect. 2018 Mar 29. pii: sextrans-2017-053367. doi: 10.1136/sextrans-2017-053367.
Key words: adolescent; m genitalium; sexual behaviour; women

15. Wu D, Li Q, Northington FJ, Zhang J. Oscillating gradient diffusion kurtosis imaging of normal and injured mouse brains. NMR Biomed. 2018 Mar 30:e3917. doi: 10.1002/nbm.3917. [Epub ahead of print]
Key words: cortex; diffusion MRI; diffusion time; hippocampus; ischemia; kurtosis; mouse brain; oscillating gradient

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July 2020 articles:
Essential Information for Human Subjects Research Teams Related to COVID-19
Coronavirus Research Billing Notices and FAQ
Managing Investigational Product Returns from Research Participants
Update to Organization Policy on Registration of Clinical Trials
Changes in HSR Recertification
Update on Insurance and Research Participant Financial Responsibility Information Sheet: Signature No Longer Required
Change in JHM IRB Review Fees for Commercially-Funded Studies
Data and Safety Monitoring Board Training Manual Now Available
Good Clinical Practice (GCP) Fundamentals: Understanding and Applying GCP to Human Subject Research
Fee Schedule Adjustment for Hospital Services Charged to Clinical Trial Budgets
Changes to NIH-funded Human Subjects Research
Free Resources for Longitudinal Clinical Research Studies
JHM IRB Reliance Requests
Sharing Partnership for Innovative Research in Translation
Johns Hopkins Institute for Clinical and Translational Research
Johns Hopkins Clinical Research Network
Visit Animal Care and Use Committee Website
Current Classes
"Interinstitutional Assurance" Agreement
Health, Safety, and Environment (HSE) presents: Safety in Research Updates
COVID-19 Funding Opportunities
Searle Scholars Program
Michael J. Fox Foundation (MJFF) Challenge
Updated Guidance from NIH on COVID-19 Flexibilities for Applicants and Recipients
COVID-19 and Research Updates
Townhall Thursdays - Providing a Pulse on What's Happening in Research at JHU
New System to Request Outgoing Subawards
Point of Contact for NIH Loan Repayment Program
JHU SOM Update on NIH Policy on Foreign Involvement
Disclosure of Payments from Foreign Educational Institutions and Government Agencies
Institutional Letter of Support Required for Institutional Training Grant Applications
Notice to the Johns Hopkins Community Regarding the National Science Foundation Grant Reporting Requirement for Harassment Findings and Actions
Prohibited Mention of Prior Review for New Replacement Applications
NIH Policy on Foreign Component Involvement
NIH Policy: Foreign Components Added to a Grant to a Domestic or Foreign Organization
Why Project Outcomes Matter in your Interim and Final Research Performance Progress Report (RPPR)
NIH Matchmaker, A Tool For Finding Similar NIH Projects
NIH Video Tutorials on How to Apply for Grants

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