Web notes  

June 2018

Pediatrics Archives

1. Brady TM, Stefani-Glücksberg A, Simonetti GD. Management of high blood pressure in children: similarities and differences between US and European guidelines. Pediatr Nephrol. 2018 Mar 28. doi: 10.1007/s00467-018-3946-y. [Epub ahead of print]
Key words: high blood pressure, pediatrics, management

2. Brown CE, Kong T, Bordón C, Yolken R, Jones-Brando L, McNulty J. One-pot, multicomponent synthesis of 2,3-disubstituted quinazolin-ones with potent and selective activity against Toxoplasma gondii.
Bioorg Med Chem Lett. 2018 Mar 16. pii: S0960-894X(18)30229-4. doi: 10.1016/j.bmcl.2018.03.036. [Epub ahead of print]
Key words: Multi-component synthesis; Quinazolinone; Toxoplasma gondii; Toxoplasmosis

3. Canan CE, Chander G, Monroe AK, Gebo KA, Moore RD, Agwu AL, Alexander GC, Lau B. High-risk prescription opioid use among people living with HIV. J Acquir Immune Defic Syndr. 2018 Mar 27. doi: 10.1097/QAI.0000000000001690. [Epub ahead of print]
Key words: opioid, HIV, high-risk use

4. Doernberg SB, Abbo LM, Burdette SD, Fishman NO, Goodman EL, Kravitz GR, Leggett JE, Moehring RW, Newland JG, Robinson PA, Spivak ES, Tamma PD, Chambers HF. Essential resources and strategies for antibiotic stewardship programs in the acute care setting. Clin Infect Dis. 2018 Mar 26. doi: 10.1093/cid/ciy255. [Epub ahead of print]
Key words: antibiotics, acute care, stewardship

5. Goldstein SD, Beaulieu RJ, Niño DF, Chun Y, Banerjee A, Sodhi CP, Hackam DJ. Early detection of necrotizing enterocolitis using broadband optical spectroscopy. J Pediatr Surg. 2018 Mar 7. pii: S0022-3468(18)30168-4. doi: 10.1016/j.jpedsurg.2018.02.083. [Epub ahead of print]
Key words: Hyperspectral imaging; Necrotizing enterocolitis; Prematurity

6. Gutierrez MJ, Sullivan KE, Fuleihan R; USIDNET Consortium, Bingham CO 3rd. Phenotypic characterization of patients with rheumatologic manifestations of common variable immunodeficiency.
Semin Arthritis Rheum. 2018 Feb 23. pii: S0049-0172(17)30654-6. doi: 0.1016/j.semarthrit.2018.02.013. [Epub ahead of print]
Key words: Autoimmunity; CVID; Primary Antibody Deficiency; Rheumatologic Disease

7. Matson PA, Fortenberry JD, Chung SE, Gaydos CA, Ellen JM. Weekly variations in feelings of trust predict incident STI within a prospective cohort of adolescent women from a US city. Sex Transm Infect. 2018 Mar 24. pii: sextrans-2017-053431. doi: 10.1136/sextrans-2017-053431. [Epub ahead of print]
Key words: adolescent; chlamydia trachomatis; neisseria gonorrhoea; sexual behaviour; sexual health

8. McClory SP, Lynch KW, Ling JP. HnRNP L represses cryptic exons. RNA. 2018 Mar 26. pii: rna.065508.117. doi: 10.1261/rna.065508.117. [Epub ahead of print]
Key words: Alternative Splicing; Cryptic Exons; Dinucleotide Repeats; HNRNPL; HnRNP L

9. Panjwani N, Xiao B, Xu L, Gong J, Keenan K, Lin F, He G, Baskurt Z, Kim S, Zhang L, Esmaeili M, Blackman S, Scherer SW, Corvol H, Drumm M, Knowles M, Cutting G, Rommens JM, Sun L, Strug LJ. Improving imputation in disease-relevant regions: lessons from cystic fibrosis. NPJ Genom Med. 2018 Mar 20;3:8. doi: 10.1038/s41525-018-0047-6. eCollection 2018.
Key words: cystic fibrosis, genotype imputation

10. Parks S, Avramopoulos D, Mulle J, McGrath J, Wang R, Goes FS, Conneely K, Ruczinski I, Yolken R, Pulver AE, Pearce BD. HLA typing using genome wide data reveals susceptibility types for infections in a psychiatric disease enriched sample. Brain Behav Immun. 2018 Mar 21. pii: S0889-1591(18)30045-X. doi: 10.1016/j.bbi.2018.03.001. [Epub ahead of print]
Key words: Bipolar disorder; Herpes virus; Histocompatibility antigen; Major histocompatibility complex; Schizophrenia; Toxoplasma

11. Rice JL, Diette GB, Suarez-Cuervo C, Brigham EP, Lin SY, Ramanathan M Jr, Robinson KA, Azar A. Allergen-specific immunotherapy in the treatment of pediatric asthma: a systematic review.
Pediatrics. 2018 Mar 23. pii: e20173833. doi: 10.1542/peds.2017-3833. [Epub ahead of print] Review.
Key words: allergen, pediatrics, asthma, immunotherapy

12. Shilkofski N, Crichlow A, Rice J, Cope L, Kyaw YM, Mon T, Kiguli S, Jung J. A standardized needs assessment tool to inform the curriculum development process for pediatric resuscitation simulation-based education in resource-limited settings. Front Pediatr. 2018 Feb 28;6:37. doi: 10.3389/fped.2018.00037. eCollection 2018.
Key words: PIPES tool; developing countries; limited-resource settings; needs assessment; neonatal resuscitation; pediatric critical care; pediatric resuscitation; simulation-based training

13. Tamma PD, Fan Y, Bergman Y, Sick-Samuels AC, Hsu AJ, Timp W, Simner PJ, Prokesch BC, Greenberg DE. Successful treatment of persistent Burkholderia cepacia complex bacteremia with ceftazidime-avibactam. Antimicrob Agents Chemother. 2018 Mar 27;62(4). pii: e02213-17. doi: 10.1128/AAC.02213-17. Print 2018 Apr.
Key words: Burkholderia cepacia complex; bacteremia; ceftazidime-avibactam; whole-genome sequencing

14. Trent M, Coleman JS, Hardick J, Perin J, Tabacco L, Huettner S, Ronda J, Felter-Wernsdorfer R, Gaydos CA. Clinical and sexual risk correlates of <i>Mycoplasma genitalium</i> in urban pregnant and non-pregnant young women: cross-sectional outcomes using the baseline data from the Women's BioHealth Study. Sex Transm Infect. 2018 Mar 29. pii: sextrans-2017-053367. doi: 10.1136/sextrans-2017-053367.
Key words: adolescent; m genitalium; sexual behaviour; women

15. Wu D, Li Q, Northington FJ, Zhang J. Oscillating gradient diffusion kurtosis imaging of normal and injured mouse brains. NMR Biomed. 2018 Mar 30:e3917. doi: 10.1002/nbm.3917. [Epub ahead of print]
Key words: cortex; diffusion MRI; diffusion time; hippocampus; ischemia; kurtosis; mouse brain; oscillating gradient

1. Frischmeyer-Guerrerio PA, Guerrerio AL, Oswald G, Chichester K, Myers L, Halushka MK, Oliva-Hemker M, Wood RA, Dietz HC. TGF? Receptor Mutations Impose a Strong Predisposition for Human Allergic Disease. Sci Transl Med. 2013 Jul 24;5(195):195ra94. doi: 10.1126/scitranslmed.3006448. PubMed PMID: 23884466.
Key words: Transforming growth factor, allergic disease, Loeys-Dietz syndrome, mutation

2. Holbrook T, Keet CA, Frischmeyer-Guerrerio PA, Wood RA. Use of ondansetron for food protein-induced enterocolitis syndrome. J Allergy Clin Immunol. 2013 Jul 25. doi:pii: S0091-6749(13)00989-5. 10.1016/j.jaci.2013.06.021.
Key words: ondansetron, food protein, enterocolitis, allergy

3. Howlett JA, Northington FJ, Gilmore MM, Tekes A, Huisman TA, Parkinson C, Chung SE, Jennings JM, Jamrogowicz JJ, Larson AC, Lehmann CU, Jackson E, Brady KM, Koehler RC, Lee JK. Cerebrovasular autoregulation and neurologic injury in neonatal hypoxic-ischemic encephalopathy. Pediatr Res. 2013 Aug 13. Doi: 10.1038/pr.2013.32. Epub ahead of print. PubMed PMID: 23942555.
Key words: neurologic injury, hypoxemia, ischemia, encephalopathy

4. Jennings JM, Woods SE, Curriero FC. The spatial and temporal association of neighborhood drug markets and rates of sexually transmitted infections in an urban setting. Health Place. 2013 Jun 27;23C:128-137. doi:10.1016/j.healthplace.2013.06.002. PubMed PMID: 23872251.
Key words: Drug markets, Ecologic analyses, Sexually transmitted infections, Social epidemiology, Spatial analyses

5. Lin DD, Barker PB, Lederman HM, Crawford TO. Cerebral abnormalities in adults with ataxia-telangiectasia. AJNR Am J Neuroradiol. 2013 Jul 25. [Epub ahead of print]
Key words: Ataxia-telangiectasia, Cerebral Abnormalities, Supratentorial, white matter

6. Stridh L, Mottahedin A, Johansson ME, Valdez RC, Northington F, Wang X, Mallard C. Toll-like receptor-3 activation increases the vulnerability of the neonatal brain to hypoxia-ischemia. J Neurosci. 2013 Jul 17;33(29):12041-51. doi: 10.1523/JNEUROSCI.0673-13.2013.
Key words: newborn, innate immune response, Toll-like receptors, neonatal brain, hypoxic-ischemic, viral infections

7. Tamma PD, Turnbull AE, Harris AD, Milstone AM, Hsu AJ, Cosgrove SE. Less is more: combination antibiotic therapy for the treatment of Gram-negative bacteremia in pediatric patients. JAMA Pediatr. 2013 Aug 5. doi: 10.1001/jamapediatrics.2013.196.
Key words: Antibiotic therapy, bacteremia, pediatrics, monotherapy, mortality, nephrotoxicity

8. Wood RA. Allergic reactions to vaccines. Pediatr Allergy Immunol. 2013 Jul 31. doi: 10.1111/pai.12102.
Key words: anaphylaxis, hypersensitivity, immunization, vaccines

9. Wu D, Xu J, McMahon MT, van Zijl PC, Mori S, Northington FJ, Zhang J. In vivo high-resolution diffusion tensor imaging of the mouse brain. Neuroimage. 2013 Jun 12;83C:18-26.doi: 10.1016/j.neuroimage.2013.06.012. [Epub ahead of print]
Key words: Brain atlas, Diffusion tensor imaging, High-resolution, In vivo, Magnetic resonance imaging, Mouse brain

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June 2018 articles:
Good Clinical Practice (GCP) Fundamentals: Understanding and Applying GCP to Human Subject Research
Fee Schedule Adjustment for Hospital Services Charged to Clinical Trial Budgets
Change in Federalwide Assurance [FWA] Numbers
Changes to NIH-funded Human Subjects Research
Free Resources for Longitudinal Clinical Research Studies
NIH requirement for Single IRB (sIRB)
JHM IRB Reliance Requests
Sharing Partnership for Innovative Research in Translation
Johns Hopkins Institute for Clinical and Translational Research
Johns Hopkins Research Network
Visit Animal Care and Use Committee Website
Current Classes
"Interinstitutional Assurance" Agreement
Health, Safety, and Environment (HSE) presents: Safety in Research Updates
WW Smith Charitable Trust Heart Disease, Cancer and AIDS Research Grants
Mallinckrodt Foundation Grants for Early-Career Faculty
Funding for Prostate Cancer Research
Michael J. Fox Foundation (MJFF) Challenge
Why Project Outcomes Matter in your Interim and Final Research Performance Progress Report (RPPR)
NIH Matchmaker, A Tool For Finding Similar NIH Projects
NIH Video Tutorials on How to Apply for Grants
NIH Policy: Foreign Components Added to a Grant to a Domestic or Foreign Organization

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Upcoming Deadlines for June and July

June Events at the Genetic Resources Core Facility


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