Web notes  

July 2020

Pathology Archives

1. Donde A, Sun M, Jeong YH, Wen X, Ling J, Lin S, Braunstein K, Nie S, Wang S, Chen L, Wong PC. Upregulation of ATG7 attenuates motor neuron dysfunction associated with depletion of TARDBP/TDP-43. Autophagy.. 2020 Apr;16(4):672-82.
Key words: ATG7, amyotrophic lateral sclerosis, frontotemporal dementia, TDP-43, motor neurons
PMID: 31242080

2. Garcia JA, Best SR, Rooper LM. HPV RNA in-situ hybridization as a diagnostic aid in papillary laryngeal lesions. Laryngoscope. 2020 Apr;130(4):955-60.
Key words: Larynx, RNA in-situ hybridization, human papillomavirus, squamous cell carcinoma, squamous papilloma
PMID: 31283030

3. Gehrie EA, Tobian AAR. PATCHing platelet data to improve transfusion. Blood. 2020 Apr;135:1309-10.
Key words: antiplatelet agents, blood platelets, cerebral hemisphere hemorrhage, adverse effects
No PMID available

4. Goel R, Josephson CD, Patel EU, Petersen MR, Makhani S, Frank SM, Ness PM, Bloch EM, Gehrie EA, Lokhandwala PM, Nellis MM, Karam O, Shaz BH, Patel RM, Tobian AAR. Perioperative transfusions and venous thromboembolism. Pediatrics. 2020 Apr;145(4):e20192351
Key words: Perioperative RBC transfusions, venous thromboembolism (VTE), RBC's, pediatric patients
PMID: 32198293

5. Hong SM, Jung D, Kiemen A, Gaida MM, Yoshizawa T, Braxton AM, Noë M, Lionheart G, Oshima K, Thompson ED, Burkhart R, Wu PH, Wirtz D, Hruban RH, Wood LD. Three-dimensional visualization of cleared human pancreas cancer reveals that sustained epithelial-to-mesenchymal transition is not required for venous invasion. Mod Pathol. 2020 Apr; 33(4):639-47.
Key words: pancreatic cancer, 3D analyses, vascular invasion

PMID: 31700162

6. Lin MT, Zheng G, Tseng LH, Zhang P, Ling H, Azad N, Gocke CD, Montgomery E, Eshleman JR. Multiclonal colorectal cancers with divergent histomorphological features and RAS mutations: one cancer or separate cancers? Hum Pathol. 2020 Apr;98:120-8.
Key words: multiclonality, colorectal cancer, KRAS, NRAS, parallel evolution
PMID: 32171651

7. Nieuwenhuis TO, Yang SY, Verma RX, Pillalamarri V, Arking DE, Rosenberg AZ, McCall MN, Halushka MK. Consistent RNA sequencing contamination in GTEx and other data sets. Nat Commun. 2020 Apr 22;11(1):1933.
Key words: RNA-sequencing, GTEx, contamination, expression
PMID: 32321923

8. Nix JS, Blakeley J, Rodriguez FJ. An update on the central nervous system manifestations of neurofibromatosis type 1. Acta Neuropathol. 2020 Apr;139(4):625-41.
Key words: Brain tumor, glioma, hydrocephalus, neurofromatosis, neurofibromin
PMID: 30963251

9. Rodriguez EF, Pastorello R, Osmani L, Hopkins M, Kryatova M, Kawamoto S, Maleki Z. Ultrasound-guided transthoracic fine-needle aspiration: a reliable tool in diagnosis and molecular profiling of lung masses. Acta Cytologica 2020 Mar- Apr;64:208-15.
Key words: Lung carcinoma, transthoracic needle aspiration, minimally invasive technique, cytology, adequacy
PMID: 31362293

10. Xing D, Zhong M, Ye F, O'Malley MT, Li S, Vang R, Ronnett BM. Ovarian intermediate trophoblastic tumors: genotyping defines a distinct category of nongestational tumors of germ cell type. Am J Surg Pathol. 2020 Apr;44(4):516-25.
Key words: pithelioid trophoblastic tumor, new classification, nongestational trophoblastic tumor, ovarian germ cell tumor, placental site trophoblastic tumor
PMID: 31688005

11. Yang G, Höti N, Chen SY, Zhou Y, Wang Q, Betenbaugh M, Zhang H. One-step enrichment of intact glycopeptides from glycoengineered chinese hamster ovary cells. Front Chem. 2020 Apr;8:240. eCollection 2020.
Key words: Intact glycopeptides, glycoengineered CHO cells, one-step enrichment, FUT8 knockout, mass spectrometry


12. Zhang SX, Carroll KC, Lewis S, Totten M, Mead P, Samuel L, Steed LL, Nolte FS, Thornberg A, Reid JL, Whitfield NN, Babady NE. Multi-center evaluation of a PCR-based digital microfluidics and electrochemical detection system for the rapid identification of 15 fungal pathogens directly from positive blood cultures. J Clin Microbiol 2020 Apr 23;58(5). pii: e02096-19
Key words: Candida, Candida auris, cryptococcus, fusarium, fungi, rhodotorula
PMID: 32075904

1. Argani P, Zhang L, Sung YS, Bacchi C, Swanson D, Dickson BC, Antonescu CR. Novel SS18-NEDD4 gene fusion in a primary renal synovial sarcoma. Genes Chromosomes Cancer. 2020 Mar;59(3):203-8.
Key words: renal, synovial sarcoma, gene fusions

PMID: 31595587

2. Carroll KC, Reid JL, Thornberg A, Whitfield NN, Trainor D, Lewis S, Wakefield T, Davis TE, Church KG, Samuel L, Mills R, Jim P, Young S, Nolte FS. Clinical performance of the novel GenMark Dx ePlex blood culture ID Gram-positive panel. J Clin Microbiol. 2020 Mar 25;58(4). pii: e01730-19.
Key words: Gram-positive bacteria, blood culture, eSensor technology, identification, multiplex nucleic acid test


3. Cho KC, Clark DJ, Schnaubelt M, Teo GC, Leprevost FDV, Bocik W, Boja ES, Hiltke T, Nesvizhskii AI, Zhang H. Deep proteomics using two dimensional data independent acquisition mass spectrometry. Anal Chem. 2020 Mar;92(6):4217-25.
Key words: two dimensional data independent acquisition (DIA), mass spectrometry, proteomics
PMID: 32058701

4. Choi HS, Won T, Hou X, Chen G, Bracamonte-Baran W, Talor MV, Jur?ová I, Szárszoi O, ?urnova L, St?íž I, Hooper JE, Melenovský V, ?iháková D. Innate lymphoid cells play a pathogenic role in pericarditis.
Cell Rep. 2020 Mar;30(9):2989-3003.e6.
Key words: IL-33, innate lymphoid cells, cardiac inflammation, eosinophils, group 2 innate lymphoid cells https://www.sciencedirect.com/science/article/pii/S2211124720302011?via%3Dihub

5. Hempel Sullivan H, Heaphy CM, Kulac I, Cuka N, Lu J, Barber JR, De Marzo AM, Lotan TL, Joshu CE, Sfanos KS. High extratumoral mast cell counts are associated with a higher risk of adverse prostate cancer outcomes. Cancer Epidemiol Biomarkers Prev. 2020 Mar;29(3):668-75.
Key words: Prostate cancer, extratumoral mast cell numbers

PMID: 31932412

6. Jones CB, Davis CM, Sfanos KS. The potential effects of radiation on the gut-brain axis. Radiat Res. 2020 Mar;193(3):209-22.
Key words: enteric nervous system, gut-brain communication, GI microbiome, lipids

PMID: 31898468

7. Kryvenko ON, Williamson SR, Schwartz LE, Epstein JI. Gleason Score 5+3=8 (Grade Group 4) prostate cancer - A rare occurrence with contemporary grading. Hum Pathol. 2020 Mar;97:40-51.
Key words: Gleason score, prostate cancer grading, grade Group

PMID: 31923450

8. Lally K, Kruse RL, Smetana H, Davis R, Roots A, Marshall C, Ness PM, DeZern AE, Gladstone DE, Brennan DC, Desai NM, Tobian AAR, Bloch EM, Gehrie EA. Isohemagglutinin titering performed on an automated solid-phase and hemagglutinin-based analyzer is comparable to results obtained by manual gel testing.
Transfusion. 2020 Mar;60(3):628-66.
Key words: blood transfusion, hemolysis, hemolytic transfusion reactions, isohemagglutinins, laboratory management
PMID: 31957889

1. Eich ML, Del Carmen Rodriguez Pena M, Schwartz L, Granada CP, Rais-Bahrami S, Giannico G, Amador BM, Matoso A, Gordetsky JB. Morphology, p16, HPV, and outcomes in squamous cell carcinoma of the penis: a multi-institutional study. Human Path. 2020 Feb;96:79-86.
Key words: HPV, immunohistochemistry, pathology, penis, squamous cell carcinoma

2. Eshleman SH, Piwowar-Manning E, Wilson EA, Lennon D, Fogel JM, Agyei Y, Sullivan PA, Weng L, Moore A, Laeyendecker O, Kosloff B, Bwalya J, Maarman G, van Deventer A, Floyd S, Bock P, Ayles H, Fidler S, Hayes R, Donnell D; HPTN 071 (PopART) Study Team. Determination of HIV status and identification of incident HIV infections in a large, community-randomized trial: HPTN 071 (PopART). J Int AIDS Soc. 2020 Feb;23(2):e25452. doi: 10.1002/jia2.25452.
Key words: HIV, HPTN, testing, Africa, treatment

3. Grabowski KM, Lessler J, Bazaale J, Nabukalu D5, Nankinga J, Nantume B, Ssekasanvu J, Reynolds SJ, Ssekubugu R, Nalugoda F, Kigozi G, Kagaayi J, Santelli JS, Kennedy C, Wawer MJ, Serwadda D, Chang LW, Gray RH. Migration, hotspots, and dispersal of HIV infection in Rakai, Uganda. Nat Commun. 2020 Feb 20;11(1):976.
Key words: HIV, Africa, Uganda

4. Haney NM, Faisal FA, Lu J, Guedes LB, Reuter VE, Scher HI, Eastham JA, Marchionni L, Joshu C, Gopalan A, Lotan TL. PTEN loss with ERG negative status is associated with lethal disease after radical prostatectomy. J Urol. 2020 Feb;203:1-7.
Key words: PTEN phosphohydrolase, mortality, oncogene proteins, prostatectomy, prostatic neoplasms
PMID: 31502941

5. Hassan O, Murati Amador B, Lombardo KA, Salles D, Cuello F, Marwaha AS, Daniels MJ, Kates M, Bivalacqua TJ, Matoso A. Clinical significance of urothelial carcinoma ambiguous for muscularis propria invasion on initial transurethral resection of bladder tumor. World J Urol. 2020 Feb;38(2):389-95.
Key words: cystectomy, muscularis propria, urothelial carcinoma

6. Kates M, Matoso A, Choi W, Baras AS, Daniels MJ, Lombardo K, Brant A, Mikkilineni N, McConkey DJ, Kamat AM, Svatek RS, Porten SP, Meeks JJ, Lerner SP, Dinney CP, Black PC, McKiernan JM, Anderson C, Drake CG, Bivalacqua TJ. Adaptive immune resistance to intravesical BCG in non-muscle invasive bladder cancer: implications for prospective BCG-unresponsive trials. Clin Cancer Res. 2020 Feb 15;26(4):882-91.
Key words: Bladder cancer, BCG, PD-L1, immunotherapy

7. Knezevic CE, Clarke W. Cancer chemotherapy: the case for therapeutic drug monitoring. Ther Drug Monit. 2020 Feb;42(1):6-19.
Key words: chemotherapy, therapeutic drug monitoring, pharmacokinetics, personalized medicine
PMID: 31568180

8. Liu C, Dillon J, Beavis AL, Liu Y, Lombardo K, Fader AN, Hung CF, Wu TC, Vang R, Garcia JE, Xing D. Prevalence of somatic and germline mutations of fumarate hydratase in uterine leiomyomas from young patients. Histopathology. 2020 Feb;76(3):354-65.
Key words: fumarate hydratase, germline mutation, hereditary leiomyomatosis and renal cell cancer (HLRCC), leiomyomas
PMID: 31564060

9. Ratmann O, Kagaayi J, Hall M, Golubchick T, Kigozi G, Xi X, Wymant C, Nakigozi G, Abler-Dorner L, Bonsall D, Gall A, Hoppe A, Kellam P, Bazaale J, Kalibbala S, Laeyendecker O, Lessler J, Nalugoda F, Chang LW, de Oliveira T, Pillay D, Quinn TC, Reynolds SJ, Spencer SEF, Ssekubugu R, Serwadda D, Wawer MJ, Gray RH, Fraser C, Grabowski MK on behalf of the Rakai Health Sciences Program and the Pangea HIV Consortium.Quantifying HIV transmission flow between high-prevalence hotspots and surrounding communities: a population-based study in Rakai, Uganda. Lancet HIV. 2020;7:e173-83.
Key words: HIV, Africa

No PMID available

10. Sadasivam M, Noel S, Rabb H, Hamad ARA. Renal double negative T cells: increasing importance in health and disease. Letter to the Editor. Ann Transl Med 2020 Feb;8(4):143
Key words: Double negative T cells, kidney, acute kidney injury, regulatory T cells
PMID: 32175435

11. Stein JE, Lipson EJ, Cottrell TR, Forde PM, Anders RA, Cimino-Mathews A, Thompson ED, Allaf ME, Yarchoan M, Feliciano J, Wang H, Jaffee EM, Pardoll DM, Topalian SL, Taube JM. Pan-tumor pathologic scoring of response to PD-(L)1 blockade. Clin Cancer Res. 2020 Feb 1;26(3):545-51.
Key words: irPRC, PD-1, neoadjuvant, pathologic response, MPR
PMID: 31672770

12. Wang Y, Xu J, Meyers CA, Gao Y, Tian Y, Broderick K, Peault B, James AW. PDGFR? marks distinct perivascular populations with different osteogenic potential within adipose tissue. Stem Cells. 2020 Feb;38(2):276-90.
Key words: mesenchymal stem cell, perivasacular stem cells, osteogenesis, adipogenesis, stem cell fate

PMID: 31742801

13. Welsh RA, Song N, Foss CA, Boronina T, Cole RN, Sadegh-Nasseri S. Lack of the MHC class II chaperone H2-O causes susceptibility to autoimmune diseases. PLOS Biology 2020 Feb;18(2):1-29 e3000590 open access.
Key words: Autoimmune diseases, T helper cells, regulatory T cells, central nervous system, antigen-presenting cells

PMID: 32069316

1. Argani P, Zhang L, Sung YS, White MJ, Miller K, Hopkins M, Small D, Pratilas CA, Swanson D, Dickson B, Antonescu CR. A novel RBMX-TFE3 gene fusion in a highly aggressive pediatric renal PEComa- a brief report. Genes Chromosomes Cancer. Jan 2020;59:58-63.
Key words: kidney, translocation, TFE3:PEComa
PMID: 31408245

2. Chen SY, Dong M, Yang G, Zhou Y, Clark DJ, Lih TM, Schnaubelt M, Liu Z, Zhang H. Glycans, glycosite, and intact glycopeptide analysis of N-Linked glycoproteins using liquid handling systems. Anal Chem. 2020 Jan 3;92(2):1680-6.
Key words: glycans, glycosite, intact glycopeptide, glycoproteins, mass spectrometry
PMID: 31859482

3. Faisal FA, Lotan LJ. The genomic and molecular pathology of prostate cancer: clinical implications for diagnosis, prognosis, and therapy. Adv Anat Pathol. 2020 Jan;27(1):11-19.
Key words: prostate cancer, genomics, molecular pathology
No PMID available

4. Fogel JM, Sivay MV, Cummings V, Wilson EA, Hart S, Gamble T, Laeyendecker O, Fernandez RE, Del Rio C, Batey DS, Mayer KH, Farley JE, McKinstry L, Hughes JP, Remien RH, Beyrer C, Eshleman SH. HIV drug resistance in a cohort of HIV-infected MSM in the United States. AIDS. 2020 Jan 1;34(1):91-101.
Key words: HIV, resistance, MSM, antiretroviral
PMID: 31634196

5. Goggins M, Overbeek KA, Brand R, Syngal S, Del Chiaro M, Bartsch DK, Bassi C, Carrato A, Farrell J, Fishman EK, Fockens P, Gress TM, van Hooft JE, Hruban RH, Kastrinos F, Klein A, Lennon AM, Lucas A, Park W, Rustgi A, Simeone D, Stoffel E, Vasen HFA, Cahen DL, Canto MI, Bruno M; International Cancer of the Pancreas Screening (CAPS) consortium. Management of patients with increased risk for familial pancreatic cancer: updated recommendations from the International Cancer of the Pancreas Screening (CAPS) Consortium. Gut. 2020 Jan;69(1):7-17.
Key words: early detection; familial pancreatic cancer; genetic predisposition; pancreatic ductal adenocarcinoma; surveillance
PMID: 31672839

6. Kim BW, Jeong YE, Wong M, Martin LJ. DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons with SOD1 mutations. Acta Neuropathol Commun 2020 Jan 31;8(1):7. Open Access
Key words: ATM, apoptosis, base excision repair, DNA N-glycosylase, motor cortex
PMID: 32005289

7. Martin AM, Bell WR, Yuan M, Harris L, Poore B, Arnold A, Engle EL, Asnaghi L, Lim M, Raabe EH, Eberhart CG. PD-L1 expression in pediatric low-grade gliomas is independent of BRAF V600E mutational status. J Neuropathol Exp Neurol 2020 Jan;79(1):74-85.
Key words: BRAF, immune response, low-grade glioma, PD-1, PD-L1, tumor infiltrating immune cells
PMID: 31819973

8. Maynard JP, Ertunc O, Kulac I, Baena Del Valle JA, De Marzo AM, Sfanos KS. IL8 expression is associated with prostate cancer aggressiveness and androgen receptor loss in primary and metastatic prostate cancer. Mol Cancer Res Jan 2020; 18(1):153-65.
Key words: prostate cancer, IL8
PMID: 31604846

9. McGonigle AM, Waters KM, Thoman SK, Vozniak SO, Ness PM, King KE, Tobian AAR, Lokhandwala PM. Solvent detergent treated pooled plasma and prevention of allergic reactions. Transfusion 2020; 60: 54-61.
Key words: transfusion reactions, thrombotic thrombocytopenic purpura (TTP), plasma

PMID: 31840276

10. Shabihkhani M, Simpson JF, White MJ, Cimino-Mathews A, Argani P. Artifactual displacement of ductal carcinoma in situ (ADDCIS) (Toothpaste Effect): A mimicker of invasive ductal carcinoma. Am J Surg Pathol. 2020 Jan;44(1):120-8.
Key words: breast, ductal carcinoma in situ, artifact, mimic
PMID: 31503011

1. Al-Hussain T, Haffner MD, Altaweel WM, Epstein JI. Plasmacytoid acinar adenocarcinoma of the prostate: a newly described variant of prostate cancer. Hum Pathol. 2019 Dec;94:86-91.
Key words: prostate cancer, plamacytoid, adenocarcinoma, variants

PMID: 31698007

2. Alruwaii ZI, Zhang Y, Larman T, Miller JA, Montgomery EA. Rosai-Dorfman disease of the digestive system-beware vasculopathy: a clinicopathologic analysis. Am J Surg Pathol. 2019 Dec;43(12):1644-52.
Key words: Rosai-Dorfman disease, vasculopathy

PMID: 31414989

3. Asrani K, Murali S, Lam B, Na CH, Phatak P, Sood A, Kaur H, Khan Z, Noë M, Anchoori RK, Talbot CC Jr, Smith B, Skaro M, Lotan TL. mTORC1 feedback to AKT modulates lysosomal biogenesis through MiT/TFE regulation. J Clin Invest. 2019 Dec;129(12):5584-99.
Key words: mTORC1, TSC, Lysosomes, TFE3, EGFR, Genetic diseases, Metabolism, Oncology
PMID: 31527310

4. Cheng W, Wang S, Zhang Z, Morgens DW, Hayes LR, Lee S, Portz B, Xie Y, Nguyen BV, Haney MS, Yan S, Dong D, Coyne AN, Yang J, Xian F, Cleveland DW, Qiu Z, Rothstein JD, Shorter J, Gao FB, Bassik MC, Sun S. CRISPR-Cas9 screens identify the RNA helicase DDX3X as a repressor of C9ORF72 (GGGGCC)n repeat-associated non-AUG translation. Neuron. 2019 Dec;104(5):885-98.e8.
Key words: neurodegeneration, repeat expansion, ALS, FTD, RNA

PMID: 31587919

5. Chui MH, Kjaer SK, Frederiksen K, Hannibal CG, Wang TL, Vang R, Shih IM. BRAFV600E -mutated ovarian serous borderline tumors are at relatively low risk for progression to serous carcinoma. Oncotarget. 2019 Dec 3;10(64):6870-8.
Key words: ovary, serous borderline tumor, BRAF, serous carcinoma


PMID: 31839880

6. Gupta RK, Rosenberg AZ, Bagnasco SM, Arend LJ. Renal crystal-storing histiocytosis involving glomeruli-A comprehensive clinicopathologic analysis. Ann Diagn Pathol. 2019 Dec;43:151403.
Key words: Crystal-storing histiocytosis (CSH), dysproteinemia, kidney biopsy, multiple myeloma, plasma cell dyscrasia
PMID: 31494491

7. Hutchings D, Jiang Z, Skaro M, Weiss MJ, Wolfgang CL, Makary MA, He J, Cameron JL, Zheng L, Klimstra DS, Brand RE, Singhi AD, Goggins M, Klein AP, Roberts NJ, Hruban RH. Histomorphology of pancreatic cancer in patients with inherited ATM serine/threonine kinase pathogenic variants. Mod Pathol. 2019 Dec;32:1806-13.
Key words: pancreatic cancer, histomorphology, ATM serine/threonine kinase, gene


8. Karaba AH, Blair PW, Martin K, Saheed MO Carroll KC Borowitz MJ. The effects of a systemwide diagnostic stewardship change on West Nile Virus disease ordering practices. Open Forum Infectious Diseases. 2019 Dec;6(12): ofz488 (online only)
Key words: West Nile Virus, Nucleic Acid Amplification tests, stewardship

No PMID available

9. Kroloff M, Crane G, Press R, Lee S, Larson S, Xian R. Next-generation sequencing analysis in posttransplant relapsed acute myeloid leukemia reveals clonal evolution and donor-derived germline variant indicating bone marrow chimerism. AJSP: Review and Reports. 2019 Nov/Dec;24(6):260-2. Case Review.
Key words: acute myeloid leukemia, next-generation sequencing, bone marrow transplant, tumor mutations


No PMID available

10. Le A, Udupa S, Zhang C. The metabolic interplay between cancer and other diseases. Trends in Cancer.. 2019 Dec;5(12):P809-21.
Key words: cancer metabolism, diabetes, cardiovascular diseases, neurological diseases, obesity

PMID: 31813458

11. Li Z, Meyers CA, Chang L, Lee S, Li Z, Tomlinson R, Hoke A, Clemens TL, James AW. Fracture repair requires TrkA signaling by skeletal sensory nerves. J Clin Invest. 2019 Dec 2;129(12):5137-50.
Key words: bone, bone healing, tissue repair, fracture repair, skeletal nerves
PMID: 31638597

12. Payer LM, Burns KH. Transposable elements in human genetic disease. Nat Rev Genet. 2019 Dec;20(12):760-72. (Review)
PMID: 31515540

13. Rooper LM, McCuiston AM, Westra WH, Bishop JA. SOX10 Immunoexpression in basaloid squamous cell carcinomas: a diagnostic pitfall for ruling out salivary differentiation. Head Neck Pathol. 2019 Dec;13(4):543-7.
Key words: basaloid squamous cell carcinoma, human papillomavirus, immunohistochemistry, SOX10, squamous cell carcinoma

14. Vizcaino MA, Tabbarah AZ, Asnaghi L, Maktabi A, Eghrari AO, Srikumaran D, Eberhart CG, Rodriguez FJ. ADAM3A copy number gains occur in a subset of conjunctival squamous cell carcinoma and its high grade precursors. Hum Pathol. 2019 Dec;94:92-97.
Key words: ADAM3A, conjunctiva, conjunctival squamous intraepithelial neoplasia, ocular surface carcinoma, squamous cell carcinoma

PMID: 31493427

1. Chui MH, Xing D, Zeppernick F, Wang ZQ, Hannibal CG, Frederiksen K, Kjaer SK, Cope L, Kurman RJ, Shih IM, Wang TL, Vang R. Clinicopathologic and molecular features of paired cases of metachronous ovarian serous borderline tumor and subsequent serous carcinoma. Am J Surg Pathol. 2019 Nov;43(11):1462-72.
Key words: Ovary, serous borderline tumor, serous carcinoma, clonality, tumor progression
PMID: 31343420

2. Donde A, Sun M, Ling JP, Braunstein KE, Pang B, Wen X, Cheng X, Chen L, Wong PC. Splicing repression is a major function of TDP-43 in motor neurons. Acta Neuropathol. 2019 Nov;138(5):813-826.
Key words: amyotrophic lateral sclerosis, cryptic exon, drosophila, motor neuron, mouse

3. Hansen G, Young S, Wu AHB, Herding E, Nordberg V, Mills R, Griego-Fullbright C, Wagner A, Ong CM, Lewis S, Yoon J, Estis J, Sandlund J, Friedland E, Carroll KC. Ultrasensitive detection of Clostridioides difficile toxins in stool using single molecule counting technology: Comparison with CCCNA free toxin detection. J Clin Microbiol. 2019 Oct 23;57(11). pii: e00719-19. doi: 10.1128/JCM.00719-19. Print 2019 Nov.
Key words: Clostridium difficile, toxin, single molecule counting technology, enzyme immunoassays
PMID: 31434724

4. Hill MR, Hopkins MR, Knezevic CE. Emerging toxidromes: a 25-year-old woman with syncope and ECG changes. Clin Chem. 2019 Nov;65(11):1357-62.
Key words: toxidromes, syncope, ECG
PMID: 31662334

5. Idrees MT, Ulbright TM, Epstein JI. Fluorescent in situ hybridization (FISH) analysis for 12p alterations in sarcomatoid yolk sac tumors. Am J Surg Pathol 2019 Nov;43(11):1566-73.
Key words: testis germ cell tumors, sarcomatoid yolk sac tumor, fluorescent in situ hybridization, isochromosome12p overrepresentation, isochromosome 12p
PMID: 31478941

6. Porter CM, Haffner MC, Kulac I, Maynard JP, Baena-Del Valle JA, Isaacs WB, Yegnasubramanian S, De Marzo AM, Sfanos KS. Lactoferrin CpG island hypermethylation and decoupling of mRNA and protein expression in the early stages of prostate carcinogenesis. Am J Pathol. 2019 Nov;189(11):2311-22.
Key words: lactoferrin (LTF), prostate cancer, hypermethylation

PMID: 31499027

7. Samarska IV, Epstein JI. Condyloma acuminatum of urinary bladder: relation to squamous cell carcinoma. Am J Surg Pathol. 2019 Nov;43(11):1547-53.
Key words: bladder carcinoma, condyloma acuminatum, urniary bladder, squamous cell carcinoma, HPV
PMID: 31368913

8. Udupa S, Nguyen S, Hoang G, Nguyen T, Quinones A, Pham K, Asaka R, Nguyen K, Elgogary A, Jung JG, Xu Q, Fu J, Thomas AG, Tsukamoto T, Hanes J, Slusher BS, Cooper AJL, Le A. Upregulation of the glutaminase II pathway contributes to glutamate production upon glutaminase 1 inhibition in pancreatic cancer. Proteomics. 2019 Nov;19(21-22):e1800451.
Key words: glutaminase 1 inhibition, glutaminase II pathway, glutamine transaminase K (GTK), ?-ketoglutaramate (KGM), patient-derived orthotopic pancreatic cancer
PMID: 31231915

9. Workneh M, Wang R, Kazmi AQ, Chambers KK, OpeneBNA, Lewis S, Goodman K, Tamma PD, Carroll K, Milstone AM, Simner PJ for the CDC Prevention Epicenters Program. Evaluation of the direct MacConkey method for identification of carbapenem-resistant gram-negative organisms from rectal swabs: re-evaluating zone diameter cutoffs. J Clin Microbiol. 2019 Nov 22;57(12). pii: e01127-19.
Key words: CRO; carbapenem-resistant organism; colonization; direct MacConkey Plate method; method
PMID: 31597748

1. Clark DJ, Dhanasekaran SM, Petralia F, Pan J, Song X, et al. Clinical proteomic tumor analysis consortium. integrated proteogenomic characterization of clear cell renal cell carcinoma. Cell 2019 Oct;179(4):964-83.e31.
Key words: ccRCC, proteogenomic, immune infiltration, drug targets, CPTAC
PMID: 31675502

2. Fischer CG, Guthrie VB, Braxton AM, Zheng L, Wang P, Song Q, Griffin JF, Chianchiano PE, Hosoda W, Niknafs N, Springer S, Molin MD, Masica D, Scharpf RB, Thompson ED, He J, Wolfgang CL, Hruban RH, Roberts NJ, Lennon AM, Jiao Y, Karchin R, Wood LD. Intraductal papillary mucinous neoplasms arise from multiple independent clones, each with distinct mutations. Gastroenterology. 2019 Oct;157(4):1123-37.e22.
Key words: PDAC, carcinogenesis, driver gene, oncogene

3. Gehrie EA, Rutter SJ, Snyder EL. Pathogen reduction: The State of the Science in 2019. Hematol Oncol Clin North Am. 2019 Oct;33(5):749-66.
Key words: blood transfusion, pathogen reduction, plasma transfusion, platelet transfusion, red blood cell transfusion
PMID: 31466602

4. Matsushita Y, Smith B, Delannoy M, Trujillo MA, Chianchiano P, McMillan R, Kamiyama H, Liang H, Thompson ED, Hruban RH, Matsui W, Wood LD, Roberts NJ, Eshleman JR. Biphenotypic differentiation of pancreatic cancer in 3-dimensional culture. Pancreas. 2019 Oct;48(9):1225-31.
Key words: biophenotype, pancreatic cancer

PMID: 31593010

5. Miller JA, An D, Shafique K, Song S, Rao RA, Viswanathan K, Eykman E, Wiles A, Ali SZ, Field A, Fadda G, Barkan GA, Layfield LJ, Rossi ED, Powers CN, Siddiqui MT, Kholova I, Baloch Z, Maleki Z. Mucoepidermoid carcinoma, acinic cell carcinoma, and adenoid cystic carcinoma on fine-needle aspiration biopsy and The Milan System: an international multi-institutional study. J Am Soc Cytopathol. 2019 Sep-Oct;8(5):270-7.
Key words: Acinic cell carcinoma, adenoid cystic carcinoma, fine-needle aspiration, mucoepidermoid carcinoma, risk of malignancy
PMID: 31104944

6. Miller KP, Venkataraman G, Gocke CD, Batista DA, Borowitz MJ, Burns KH, Pratz K, Duffield AS. Bone marrow findings in patients with acute promyelocytic leukemia treated with arsenic trioxide. Am J Clin Pathol. 2019 Oct 7;152(5):675-85.
Key words: acute promyelocytic leukemia, all-trans retinoic acid, arsenic trioxide
PMID: 31305869

7. Palumbo PJ, Zhang Y, Fogel JM, Guo X, Clarke W, Breaud A, Richardson P, Piwowar-Manning E, Hart S, Hamilton EL, Hoa NTK, Liulchuk M, Anandari L, Ha TV, Dumchev K, Djoerban Z, Hoffman I, Hanscom B, Miller WC, Eshleman SH. HIV drug resistance in persons who inject drugs enrolled in an HIV prevention trial in Indonesia, Ukraine, and Vietnam: HPTN 074. PLoS One. 2019 Oct 10;14(10):e0223829.
Key words: HIV, resistance, substance use, HPTN

8. Tseng LH, De Marchi F, Pallavajjalla A, Rodriguez E, Xian R, Belchis D, Gocke CD, Eshleman JR, Illei P, Lin MT. Clinical validation of discordant trunk driver mutations in paired primary and metastatic lung cancer specimens. Am J Clin Pathol. 2019 Oct;152(5):570-81.
Key words: trunk driver mutations, lung cancers, KRAS, EGFR, quality assessment
PMID: 31264684

9. Verdugo D, Voltaggio L, Hoot A, Rodriguez FJ. Cerebral pleomorphic liposarcoma: Clinicopathologic findings. Clin Neuropathol. 2019 Sep/Oct;38(5):233-7.
Key words: clinopathology, cerebral pleomorphic liposarcoma

10. Ware AD, Wake L, Brown P, Webster JA, Smith BD, Duffield AS. B-lymphoid blast phase of chronic myeloid leukemia: A case report and review of the literature. AJSP: Reviews & Reports: September/October 2019;24(5):191-5.
Key words: Leukemia, TKI therapy, B-lymphoid, bone marrow


1. Cheah JX, Nieuwenhuis TO, Halushka MK. An expanded proteome of cardiac t-tubules. Cardiovasc Pathol. 2019 Sept-Oct;42:15-20.
Key words: Caveolin, proteomics, T-tubule

PMID: 31202980

2. Duregon E, Schneider J, DeMarzo AM, Hooper JE. Rapid research autopsy is a stealthy but growing contributor to cancer research. Cancer. 2019 Sep;125(17):2915-9.
Key words: autopsy, cancer research, metastases, postmortem, rapid autopsy
PMID: 31090935

3. Hsu C, Salazar MG, Miller S, Meyers C, Ding C, Hardy WR, Peault B, James AW. Comparison of human tissue microarray to human pericyte transcriptome yields novel perivascular cell markers. Stem Cells Dev. 2019 Sep 15;28(18):1214-23.
Key words: pericyte, perivascular stem cells, mesenchymal stem cells
PMID: 31264500

4. Khani F, Wobker SE, Hicks JL, Robinson BD, Barbieri CE, De Marzo AM, Epstein JI, Pritchard CC, Lotan TL. Intraductal carcinoma of the prostate in the absence of high-grade invasive carcinoma represents a molecularly distinct type of in situ carcinoma enriched with oncogenic driver mutations. J Pathol. 2019 Sep;249(1):79-89.
Key words: MAPK, PI3K, intraductal carcinoma, oncogenic driver mutations, prostate cancer

5. Li J, Lai H, Chen S, Kickler T, Lai S. Cocaine use modifies the association between antiretroviral therapy and endothelial dysfunction among adults with HIV infection. J Med Virol 2019 Sep;91(9):1660-7.
Key words: HIV infection, antiretroviral therapy, cocaine use, endothelin-1, von Willebrand factor antigen

6. Mitchell SL, Simner PJ. Next-generation sequencing in clinical microbiology: are we there yet? Clin Lab Med. 2019 Sep;39(3):405-18.
Key words: clinical microbiology, infectious disease, metagenomics next-generations sequencing (mNGS), Next-generation sequencing (NGS), targeted next-generation sequencing (tNGS)
PMID: 31383265

7. Park Y, Chui MH, Suryo Rahmanto Y, Yu ZC, Shamanna RA, Bellani MA, Gaillard S, Ayhan A, Viswanathan A, Seidman MM, Franco S, Leung AKL, Bohr VA, Shih IM, Wang TL. Loss of ARID1A in tumor cells renders selective vulnerability to combined ionizing radiation and PARP inhibitor therapy. Clin Cancer Res. 2019 Sep 15;25(18):5584-94.
PMID: 31196855

8. Patel EU, Bloch EM, Grabowski MK, Goel R, Lokhandwala PM, Brunker PAR, White JL, Shaz B, Ness PM, Tobian AAR. Sociodemographic and behavioral characteristics associated with blood donation in the United States: a population-based study. Transfusion. 2019 Sep;59(9):2899-907.
PMID: 31222779

9. Sadegh-Nasseri S, Kim A. Selection of immunodominant epitopes during antigen processing is hierarchical. Mol Immunol. 2019 Sep;113:115-9.
Key words: immunodominance, antigen processing, T cell epitope, mass spectrometry
PMID: 30146122

10. Wang Q, Yang G, Wang T, Yang W, Betenbaugh MJ, Zhang H. Characterization of intact glycopeptides reveals the impact of culture media on site-specific glycosylation of EPO-Fc fusion protein generated by CHO-GS cells. Biotechnol Bioeng. 2019 Sep;116(9):2303-15.
Key words: CHO-GS cells, EPO-Fc protein, culture media, intact glycopeptide analysis, site-specific glycosylation

11. Ware AD, Murdock T, Voltaggio L, Windon AL, Troncoso JC, Hruban RH, White MJ. The "Race" toward diversity, inclusion, and equity in pathology: The Johns Hopkins Experience. Acad Pathol 2019 Sep 8;6:2374289519873104.
Key words: diversity, medical student, outreach, pathology, pipeline


12. Wobker SE, Matoso A, Pratilas CA, Mangray S, Zheng G, Lin MT, Debeljak M, Epstein JI, Argani P. Metanephric adenoma-epithelial Wilms tumor overlap lesions: an analysis of BRAF status. Am J Surg Pathol. 2019 Sep;43(9):1157-69.
Key words: Wilms, metanephric, BRAF, kidney

13. Xing D, Berrebi AA, Liu C, Richmond A, Vang R, Ronnett BM. An epithelioid smooth muscle neoplasm mimicking a signet ring cell carcinoma in the ovary. Int J Gynecol Pathol. 2019 Sep;38(5):464-9.
Key words: ovary, epithelioid muscle neoplasm, signet ring cell carcinoma


14. Xu J, Wang Y, Hsu CY, Gao Y, Meyers CA, Chang L, Zhang L, Broderick K, Ding C, Peault B, Witwer K, James AW. Human perivascular stem cell-derived extracellular vesicles mediate bone repair. Elife. 2019 Sep 4;8. pii: e48191. doi: 10.7554/eLife.48191.
Key words: osteogenesis, bone formation, bone tissue engineering, mesenchymal stem cells, exosomes

15. Zheng G, Richmond A, Liu C, Berrebi A, Pallavajjala A, Haley L, Stone RL, McCarthy E, Vang R, Xing D. Clinicopathologic features and genetic alterations of a primary osteosarcoma of the uterine corpus. Int J Gynecol Pathol. 2019 Sep;38(5):414-9.
Key words: osteosarcoma, uterus, clinicopathology
PMID: 29629977

1. Boivin MJ, Maliwichi-Senganimalunje L, Ogwang LW, Kawalazira R, Sikorskii A, Familiar-Lopez I, Kuteesa A, Nyakato M, Mutebe A, Namukooli JL, Mallewa M, Ruiseñor-Escudero H, Aizire J, Taha TE, Fowler MG. Neurodevelopmental effects of ante-partum and post-partum antiretroviral exposure in HIV-exposed and uninfected children versus HIV-unexposed and uninfected children in Uganda and Malawi: a prospective cohort study. Lancet HIV. 2019 Aug;6(8):PE518-E530.
Key words: HIV exposure, Uganda, Malawi, neurodevelopmental effects
PMID: 31122797

2. Fenwick AJ, Carroll KC. Practical problems when incorporating rapidly changing microbial taxonomy into clinical practice. Clin Chem Lab Med. 2019 Aug 27;57(9):e238-e240. (Letter to Editor)
Key words: microbiology, new, problems, taxonomy

PMID: 30721139

3. Groot VP, Mosier S, Javed AA, Teinor JA, Gemenetzis G, Ding D, Haley LM, Yu J, Burkhart RA, Hasanain A, Debeljak M, Kamiyama H, Narang A, Laheru DA, Zheng L, Lin MT, Gocke CD, Fishman EK, Hruban RH, Goggins MG, Molenaar IQ, Cameron JL, Weiss MJ, Velculescu VE, He J, Wolfgang CL1, Eshleman JR. Circulating tumor DNA as a clinical test in resected pancreatic cancer. Clin Cancer Res. 2019 Aug;25(16):4973-84.
Key words: tumor DNA, pancreatic cancer
PMID: 31142500

4. Hamad ARA, Sadasivam M, Rabb H. Hybrid lipids, peptides, and lymphocytes: new era in type 1 diabetes research. J Clin Invest. 2019 Aug;130:3527-9.
Key words: lipids, peptides, lymphocytes, type 1 diabetes

5. Pederzoli F, Murati Amador B, Samarska I, Lombardo KA, Kates M, Bivalacqua TJ, Matoso A. Diagnosis of urothelial carcinoma in situ using blue light cystoscopy and the utility of immunohistochemistry in blue light-positive lesions diagnosed as atypical. Hum Pathol. 2019 Aug;90:1-7.
Key words: Blue light cystoscopy, photosensitizing agents, urothelial carcinoma in situ
PMID: 31071342

6. Rodriguez FJ, Graham MK, Brosnan-Cashman JA, Barber JR, Davis C, Vizcaino MA, Palsgrove DN, Giannini C, Pekmezci M, Dahiya S, Gokden M, Noë M, Wood LD, Pratilas CA, Morris CD, Belzberg A, Blakeley J, Heaphy CM. Telomere alterations in neurofibromatosis type 1-associated solid tumors. Acta Neuropathol Commun. 2019 Aug;7(1):139.
Key words: telomere, neurofibromatosis, solid tumors

7. Tamma PD, Kazmi A, Bergman Y, Goodman KE, Ekunseitan E, Amoah J, Simner PJ. The likelihood of developing a carbapenem-resistant Enterobacteriaceae infection during a hospital stay. Antimicrob Agents Chemother. 2019 Jul 25;63(8). pii: e00757-19. doi: 10.1128/AAC.00757-19. Print 2019 Aug.
Key words: CRE, ICU, carbapenem resistance, multidrug-resistant organisms

1. Gehrie EA, M. Frank SM, Visagie M, Grabowski MK, Tobian AAR, Strockbine VS, DeMario VM, Lawrence C, Hambley B, Uglik K, Ness PM, Dezern A, Bloch EM. One-unit compared to two-unit unit platelet transfusions for adult oncology outpatients. Vox Sang. 2019 Jul;114(5):517-22.
Key words: blood components, patient blood management, platelet concentrates, platelet transfusion, refractoriness (platelets), transfusion strategy
PMID: 31056742

2. Hou X, Chen G, Bracamonte-Baran W, Choi HS, Diny NL, Sung J, Hughes D, Won T, Wood MK, Talor MV, Hackam DJ, Klingel K, Davogustto G, Taegtmeyer H, Coppens I, Barin JG, ?iháková D. The cardiac microenvironment instructs divergent monocyte fates and functions in myocarditis. Cell Rep. 2019 Jul;28(1):172-189.e7
Key words: myocarditis, macrophages, cardiac immunity

PMID: 31269438

3. Lokhandwala PM, Tseng LH, Rodriguez E, Zheng G, Pallavajjalla A, Gocke CD, Eshleman JR, Lin MT. Clinical mutational profiling and categorization of BRAF mutations in melanomas using next generation sequencing. BMC Cancer. 2019 Jul;19(1):665.
Key words: BRAF, categorization, kinase-impaired, melanoma, NRAS

4. Springer S, Masica DL, Dal Molin M, Douville C, Thoburn CJ, Afsari B, Li L, Cohen JD, Thompson E, Allen PJ, Klimstra DS, Schattner MA, Schmidt CM, Yip-Schneider M, Simpson RE, Fernandez-Del Castillo C, Mino-Kenudson M, Brugge W, Brand RE, Singhi AD, Scarpa A, Lawlor R, Salvia R, Zamboni G, Hong SM, Hwang DW, Jang JY, Kwon W, Swan N, Geoghegan J, Falconi M, Crippa S, Doglioni C, Paulino J, Schulick RD, Edil BH, Park W, Yachida S, Hijioka S, van Hooft J, He J, Weiss MJ, Burkhart R, Makary M, Canto MI, Goggins MG, Ptak J, Dobbyn L, Schaefer J, Sillman N, Popoli M, Klein AP, Tomasetti C, Karchin R, Papadopoulos N, Kinzler KW, Vogelstein B, Wolfgang CL, Hruban RH, Lennon AM. A mulitmodality test to guide the management of patients with a pancreatic cyst. Sci Transl Med. 2019 Jul;11(501). pii: eaav4772. doi: 10.1126/scitranslmed.aav4772.
PMID: 31316009

5. White JL, Patel EU, Abraham AG, Grabowski, MK, Arav-Boger R, Avery RK, Thomas DL, Tobian AAR. Prevalence, magnitude and genotype distribution of urinary cytomegalovirus (CMV) shedding among CMV-seropositive children and adolescents in the United States. Open Forum Infect Dis. 2019 Jul;6(7):ofz272.
Key words: National Health and Nutrition Examination Survey (NHANES), cytomegalovirus (CMV), genotype, shedding

6. Xing D, Zheng G, Pallavajjala A, Schoolmeester JK, Liu Y, Haley L, Hu Y, Liu L, Logan L, Lin Y, Pearce KE, Sattler CA, Tsai YC, Vang R, Hung CF, Wu TC, Ronnett BM. Lineage-specific alterations in gynecologic neoplasms with choriocarcinomatous differentiation: implications for origin and therapeutics. Clin Cancer Res. 2019 Jul;25(14):4516-29.
Key words: Gynecologic tumors, choriocarcinomatous differentiation, mutations, single nucleotide polymorphisms, PD-L1
PMID: 31010836

1. Ciháková D, Eaton WW, Talor MV, Harkus UH, Demyanovich H, Rodriguez K, Feldman S, Kelly DL. Gut permeability and mimicry of the Glutamate Ionotropic Receptor NMDA type Subunit Associated with protein 1 (GRINA) as potential mechanisms related to a subgroup of people with schizophrenia with elevated antigliadin antibodies (AGA IgG). Schizophr Res. 2019 Jun;208:414-9.
Key words: AGA, ASCA, GRINA, gliadin, gluten sensitivity, schizophrenia
PMID: 30685393

2. Hickey JW, Dong Y, Chung JW, Salathe SF, Pruitt HC, Li X, Chang C, Fraser AK, Bessell Ca, Ewald AJ, Gerecht S, Mao HQ, Schneck JP. Engineering an artificial T?cell stimulating matrix for immunotherapy. Advanced Materials. 2019 Jun;31(23):e1807359.
Key words: adoptive T cell therapy, artificial matrix, extracellular matrix, hydrogel, immunotherapy
PMID: 30968468

3. Hruban RH, Gaida MM, Thompson E, Hong SM, Noë M, Brosens LA, Jongepier M, Offerhaus GJA, Wood LD. Why is pancreatic cancer so deadly? The pathologist's view. J Pathol. 2019 Jun;248(2):131-41.
Key words: pancreas, pancreas cancer, pancreatic cancer, prognosis, tumor immune microenvironment
PMID: 30838636

4. James AW, Péault B. Perivascular mesenchymal progenitors for bone regeneration. J Orthop Res. 2019 Jun;37(6):1221-8.
Key words: pericyte, stem cell, bone, bone repair
PMID: 30908717

5. Kwon R, Duffield AS. HTLV-1-associated adult T-cell leukemia/lymphoma with disseminated strongyloidiasis. Blood. 2019 Jun 13;133(24):2623.
Key words: infectious diseases, Strongyloides, leukemia, lymphoma, HTLV-1
PMID: 31196878

6. Murati Amador B, Matoso A. Testicular germ cell tumor showing concurrent PNET and neuroglial neoplasms With Wide Spectrum of Grades. Am J Surg Pathol. 2019 Jun;43(6):865-7. (letter to Editor)
Key words: germ cell tumor, neuroglial neoplasm, PNET
PMID: 31091205

7. Sono T, Ware AD, McCarthy EF, James AW. Chondromyxoid fibroma of the pelvis: institutional case series with a focus on distinctive features. Int J Surg Pathol. 2019 Jun;27(4):352-9.
Key words: Bone tumors, skeletal tumors, cartilage tumors, chondrosarcoma
PMID: 30580642

8. Toonstra C, Hu Y, Zhang H. Deciphering the roles of N-Glycans on collagen-platelet interactions. J Proteome Res. 2019 Jun 7;18(6):2467-77.
Key words: N-glycans, affinity purification, collagen, collagen-platelet interactions, glycoproteins
PMID: 31055923

1. Ahmed R, Omidian Z, Giwa A, Cornwell B, Majety N, Bell DR, Lee S, Zhang H, Michels A, Desiderio S, Sadegh-Nasseri S, Rabb H, Gritsch S, Suva ML, Cahan P, Zhou R, Jie C, Donner T, Hamad ARA. A public BCR present in a unique dual-receptor-expressing lymphocyte from Type 1 diabetes patients encodes a potent T cell autoantigen. Cell. 2019 May 30;177(6):1583-99.
Key words: DEs, autoantigen, duel expressers, insulin mimotope, islet autoantigen, type 1
PMID: 31150624

2. Arnold CAA, Kherad Pezhouh M, Lam-Himlin D, Pittman M, VandenBussche C, Voltaggio L. 90Y-TheraSpheres®: The New Look of Yttrium-90. Am J Surg Pathol. 2019 May;43(5):688-94.
Key words: hepatic malignancy, radiation therapy, Yttrium-90
No PMID available

3. Birkness J, Lam-Himlin D, Byrnes K, Wood L, Voltaggio L. The inverted appendix - a potentially problematic diagnosis: clinicopathologic analysis of 21 cases. Histopathology. 2019 May;74(6):853-60.
Key words: appendiceal intussusception, inverted appendix,low-grade appendiceal mucinous neoplasm, neuroendocrine tumour, traditional serrated adenoma
PMID: 30667075

4. Clark DJ, Hu Y, Schnaubelt M, Fu Y, Ponce S, Chen S-Y, Zhou Y, Shah P, Zhang H. Simple tip-based sample processing method for urinary proteomic analysis. Analytical Chemistry. 2019 May 7; 91(9):5517-33.
Key words: proteomics, automated sample processing, urine proteome, mass spectrometry
PMID: 30924636

5. Faisal FA, Tosoian JJ, Han M, Macura KJ, Pavlovich CP, Lotan TL. Clinical, pathologic, and oncologic findings of radical prostatectomy patients with extraprostatic extension diagnosed on pre-operative prostate biopsy. J Urol. 2019 May;201(5):937-42.
Key words: biopsy, needle, neoplasm staging, prostatectomy, prostatic neoplasms, surgical pathology
PMID: 30414957

6. Guarner J, Schroeder LF, Amukele TK. Three approaches to creating an essential diagnostics list. Am J Clin Pathol. 2019 May;151(5):443-45.
Key words: EDL, essential diagnostics, List

7. Haddaway K, Bloch EM, Tobian AAR, Frank SM, Sikorski R, Cho BC, Zheng G, Jani J, Lokhandwala PM, Lawrence CE, Blagg L, Ness PM, Kickler TS, Gehrie EA. Hemostatic properties of cold?stored whole blood leukoreduced using a platelet?sparing versus a non-platelet?sparing filter. Transfusion. 2019 May;59(5):1809-17.
Key words: transfusion Practices, blood component preparations, hemostasis, platelets
PMID: 30741432

8. Kopp JB, Rosenberg AZ. One actor, many roles: histopathologies associated with APOL1 genetic variants. Adv Anat Pathol. 2019 May;26(3):215-9. (Review)
Key words: histopathology, apolipoprotein L1, glomerular disease
PMID: 30624253

9. Kaur HB, Lu J, Guedes LB, Maldonado L, Reitz L, Barber JR, De Marzo AM, Tomlins SA, Sfanos KS, Eisenberger M, Schaeffer EM, Joshu CE, Lotan TL. TP53 missense mutation is associated with increased tumor-infiltrating T-cells in primary prostate Cancer. Hum Pathol. 2019 May;87:95-102.
Key words: CD3, CD8, FOXP3, Prostatic adenocarcinoma, T cells, TP53, Tumor-infiltrating lymphocytes
PMID: 30851334

10. Maleki Z, Baloch Z, Lu R, Shafique K, Song SJ, Viswanathan K, Rao RA, Lefler H, Fatima A, Wiles A, Jo VY, Wang H, Fadda G, Powers CN, Ali SZ, Pantanowitz L, Siddiqui MT, Nayar R, Klijanienko J, Barkan GA, Krane JF, Rossi ED, Callegari F, Kholová I, Bongiovanni M, Faquin WC, Pusztaszeri MP. Application of the Milan System for Reporting Submandibular Gland Cytopathology: An international, multi?institutional study. Cancer Cytopathol. 2019 May;127(5):306-15.
Key words: Milan System for Reporting Salivary Gland Cytopathology (MRSSGC), atypia of undetermined significance (AUS), benign neoplasm, fine-needle aspiration (FNA), malignant
PMID: 31050186

11. Mocci E, Debeljak M, Klein AP, Eshleman JR. A new fast phasing method based on haplotype subtraction. J Mol Diagn. 2019 May;21(3):427-36.
Key words: alleles, genotypes, phasing, algorithms heterozygotes
PMID: 30872187

12. Omidian Z, Ahmed R, Giwa A, Donner T, Hamad ARA. IL-17 and limits of success. Cell Immunol. 2019 May;339:33-40.
Key words: autoimmune diseases, clinical trials, IL-17, immunotherapy, interleukin-17
PMID: 30765202

13. Patel EU, White JL, Bloch EM, Grabowski MK, Gehrie EA, Lokhandwala PM, Brunker PAR, Goel R, Shaz BH, Ness PM, Tobian AAR. Association of blood donation with iron deficiency among adolescent and adult females in the United States: a nationally representative study. Transfusion. 2019 May;59:1723-33.
Key words: blood, blood donation, iron deficiency, adolescent

14. Sfanos KS, Joshu CE. IBD as a risk factor for prostate cancer: what is the link? Nat Rev Urol. 2019 May;16(5):271-2.
Key words: IBD, prostate cancer, risk factors

15. Skaro M, Nanda N, Gauthier C, Felsenstein M, Jiang Z, Qiu M, Shindo K, Yu J, Hutchings D, Javed AA, Beckman R, He J, Wolfgang CL, Thompson E, Hruban RH, Klein AP, Goggins M, Wood LD, Roberts NJ. Prevalence of germline mutations associated with cancer risk in patients with intraductal papillary mucinous neoplasms. Gastroenterology. 2019 May;156(6):1905-13.
Key words: cancer, genetics, pancreas, predisposition, germline genetics


PMID: 30716324

1. Bell DT, Bergman Y, Kazmi AQ, Lewis S, Tama PD, Simner PJ. A novel phenotypic method to screen for plasmid-mediated colistin resistance among enterobacteriales. J Clin Microbiol. 2019 Apr;57:e00040-19.
Key words: colistin, mcr, phenotypic method, plasmid-mediated colistin resistance
PMID: 30842232

2. Eshleman SH, Laeyendecker O, Kammers K, Chen A, Sivay MV, Kottapalli S, Sie BM, Yuan T, Monaco DR, Mohan D, Wansley D, Kula T, Morrison C, Elledge SJ, Brookmeyer R, Ruczinski I, Larman HB. Comprehensive profiling of HIV antibody evolution. Cell Rep. 2019 Apr 30;27(5):1422-33.e4.
Key words: antibody response to HIV, antibody profiling, HIV incidence, antibody biomarker serosignature
PMID: 31042470

3. Guarner J, Schroeder LF, Amukele TK. Three approaches to creating an essential diagnostics list. Am J Clin Pathol. 2019 Apr 2;151(5):443-5.
Key words: EDL, essential diagnostics, list
PMID: 30551217

4. Kacker S, Bloch EM, Ness PM, Gehrie EA, Marshall CE, Lokhandwala PM, Tobian AAR. Financial impact of alternative approaches to reduce bacterial contamination of platelet transfusions. Transfusion. 2019 Apr;59(4):1291-9.
PMID: 30623459

5. Li QK, Pavlovich CP, Zhang H, Kinsinger CR, Chan DW. Challenges and opportunities in the proteomic characterization of clear cell renal cell carcinoma (ccRCC): A critical step towards the personalized care of renal cancers. (review) Semin Cancer Biol. 2019 Apr;55:8-15.
Key words: Clear cell renal cell carcinoma (ccRCC), clinical application, personalized medicine, protein profiling, proteomics

PMID: 30055950

6. c A. Evaluation and reporting of biopsies from the columnar-lined esophagus and gastro-esophageal junction (GEJ). Ann Diagn Pathol. 2019 April;39:111-7.
Key words: Barrett's Esophagus, columnar lined esophagus, intestinal metaplasia of the gastric cardia, Prague classification
PMID: 30055950

7. Natsumeda M, Liu Y, Nakata S, Miyahara H, Hanaford A, Ahsan S, Stearns D, Skuli N, Kahlert UD, Raabe EH, Rodriguez F, Eberhart CG. Inhibition of enhancer of zest homologue 2 is a potential therapeutic target for high-MYC medulloblastoma. Neuropathology. 2019 Apr;39(2):71-77.
Key words: EZH2, EZH2 inhibitor, H3K27me3, MYC, medulloblastoma
PMID: 30632221

8. Nguyen T, Kirsch BJ, Asaka R, Nabi K, Quinones A, Tan J, Antonio MJ, Camelo F, Li T, Nguyen S, Hoang G, Nguyen K, Udupa S, Sazeides C, Shen YA, Elgogary A, Reyes J, Zhao L, Kleensang A, Chaichana KL, Hartung T, Betenbaugh MJ7, Marie SK, Jung JG, Wang TL, Gabrielson E, Le A. Uncovering the role of N-acetyl-aspartyl-glutamate as a glutamate reservoir in cancer. Cell Rep. 2019 Apr 9;27(2):491-501.e6.
Key words: N-acetyl-aspartyl-glutamate (NAAG), glutamate carboxypeptidase II (GCPII), glutaminase inhibitor, glutamate deprivation, glutamate reservoir, stable isotoperesolved metabolomics


9. Patel EU, Mehta SH, Boon DE, Quinn TC, Thomas DL, Tobian AAR. Limited coverage of hepatitis C virus testing in the United States, 2013-2017. Clin Infect Dis. 2019 Apr 8;68(8):1402-5.
Key words: HCV, National Health Interview Survey, baby boomer, hepatitis, screening
PMID: 30239645

10. Trabzonlu L, Kulac I, Zheng Q, Hicks JL, Haffner MC, Nelson WG, Sfanos KS, Ertunc O, Lotan TL, Heaphy CM, Meeker AK, Yegnasubramanian S, De Marzo AM. Molecular pathology of high-grade prostatic intraepithelial neoplasia: challenges and opportunities. Cold Spring Harb Perspect Med. 2019 Apr 1;9(4). pii: a030403.
Key words: molecular pathology, prostatic intraepithelial neoplasia

11. Wang Q, Chung CY, Yang W, Yang G, Chough S, Chen Y, Yin B, Bhattacharya R, Hu Y, Saeui CT, Yarema KJ, Betenbaugh MJ, Zhang H. Combining butyrated ManNAc with glycoengineered CHO cells improves EPO glycan quality and production. Biotechnol J. 2019 Apr;14(4):e1800186.
Key words: EPO; butyrated ManNAc; glycoengineering; intact glycopeptide analysis, sialylation

12. Wang C, Höti N, Lih TM, Sokoll LJ, Zhang R, Zhang Z, Zhang H, Chan DW. Development of a glycoproteomic strategy to detect more aggressive prostate cancer using lectin-immunoassays for serum fucosylated PSA. Clin Proteomics. 2019 Apr 6;16:13. doi: 10.1186/s12014-019-9234-4. eCollection 2019.
Key words: fucosylated PSA, glycoproteomic, lectin-immunoassays, prostate cancer
PMID: 30996714

13. Zheng G, Tseng LH, Haley L, Ibrahim J, Bynum J, Xian R, Gocke CD, Eshleman JR, Lin MT. Clinical validation of coexisting driver mutations in colorectal cancers. Hum Pathol. 2019 Apr;86:12-20.
Key words: BRAF, coexisting mutation, colorectal cancer, KRAS, NRAS, PIK3CA
PMID: 30481508

1. Antonarakis ES, Shaukat F, Isaacsson Velho P, Kaur H, Shenderov E, Pardoll DM, Lotan TL. Clinical features and therapeutic outcomes in men with advanced prostate cancer and DNA mismatch repair gene mutations. Eur Urol. 2019 Mar;75(3):378-82.
Key words: MSH2, MSH6, microsatellite instability, mismatch repair, prostate cancer
PMID: 30337059

2. Asnaghi L, White DT, Key N, Choi J, Mahale A, Alkatan H, Edward DP, Elkhamary SM, Al-Mesfer S, Maktabi A, Hurtado CG, Lee GY, Carcaboso AM, Mumm JS, Safieh LA, Eberhart CG. ACVR1C/SMAD2 signaling promotes invasion and growth in retinoblastoma. Oncogene. 2019 Mar;38:2056-75.
Key words: Retinoblastoma, TGF-?, gene expression, ACVR1C/SMAD2 pathway
PMID: 30401983

3. Bracamonte-Baran W, Chen G, Hou X, Talor MV, Choi HS, Davogustto G, Taegtmeyer H, Sung J, Hackam DJ, Nauen D, ?iháková D. Non-cytotoxic cardiac innate lymphoid cells are a resident and quiescent type 2-commited population. Front Immunol. 2019 Mar;10:634.
Key words: innate lymphoid cells, IL-33, heart, myocarditis, myocardial infarction, fibroblasts

4. Di Dalmazi G, Chalan P, Caturegli P. MYMD-1, a Novel Immunometabolic Regulator, Ameliorates Autoimmune Thyroiditis via Suppression of Th1 Responses and TNF-? Release. J Immunol. 2019 Mar;202(5):1350-62.
Key words: thyroiditis, MYMD-1, Hashimoto thyroiditis, autoimmunity, smoking
PMID: 30674573

5. Foster P, Sokoll L, Li J, Gerstenblith G, Fishman EK, Kickler T, Chen S, Tai H, Lai H, Lai S. Circulating levels of cardiac troponin T are associated with coronary noncalcified plaque burden in HIV-infected adults: a pilot study. Int J STD AIDS. 2019 Mar;30(3):223-30.
Key words: HIV infection, noncalcified plaque volume, cardiac troponin T, chronic kidney disease, injection
PMID: 30381028

6. Kuboki Y, Fischer CG, Beleva Guthrie V, Huang W, Yu J, Chianchiano P, Hosoda W, Zhang H, Zheng L, Shao X, Thompson ED, Waters K, Poling J, He J, Weiss MJ, Wolfgang CL, Goggins MG, Hruban RH, Roberts NJ, Karchin R, Wood LD. Single-cell sequencing defines genetic heterogeneity in pancreatic cancer precursor lesions. J Pathol. 2019 Mar;247(3):347-56.
Key words: genetic heterogeneity, intraductal papillary mucinous neoplasm, pancreatic cancer precursor lesion, single-cell sequencing, somatic mutation
PMID: 30430578

7. Lakis NS, Lombardo KA, Mangray S, Netto GJ, Salles D, Matoso A. INSL3 Expression in Leydig Cell Hyperplasia and Leydig Cell Tumors. Appl Immunohistochem Mol Morphol. 2019 Mar;27(3):203-9.
Key words: Leydig cell tumor, Leydig cell hyperplasia, sex cord stromal tumor, INSL3, testis
PMID: 29084059

8 Matoso A, Idrees MT, Rodriguez FJ, Ibrahim J, Perrino CM, Ulbright TM, Epstein JI. Neuroglial differentiation and neoplasms in testicular germ cell tumors lack immunohistochemical evidence of alterations characteristic of their CNS counterparts: A Study of 13 Cases. Am J Surg Pathol. 2019 Mar;43(3):422-31.
Key words: germ cell tumor, teratoma, neuroglia, glioma

9. Rodriguez EF, Judd Fite J, Chowsilpa S, Maleki Z. Insulinoma-associated protein 1 immunostaining on cytology specimens: an institutional experience. Hum Pathol. 2019 March;85:128-35.
Key words: cytology, INSM1, insulinoma-associated protein 1, neuroendocrine markers, small cell carcinoma

10. Rooper LM, Sharma R, Gocke CD, Belchis DA. The Utility of NKX2.2 and TLE1 Immunohistochemistry in the Differentiation of Ewing Sarcoma and Synovial Sarcoma. Appl Immunohistochem Mol Morphol. 2019 Mar;27(3):174-9.
Key words: Ewing sarcoma, synovial sarcoma, immunohistochemistry, molecular testing

11. Sono T, Meyers CA, Miller D, Ding C, McCarthy EF, James AW. Overlapping features of rapidly progressive osteoarthrosis and Charcot arthropathy. J Orthop 2019 Mar 12;16(3):260-4.
Key words: Osteoarthritis, arthropathy, Charcot joint, joint disease, RPOA

12. Steranka JP, Tang Z, Grivainis M, Huang CRL, Payer LM, Rego FOR, Miller TLA, Galante PAF, Ramaswami S, Heguy A, Fenyo D, Boeke JD, Burns KH. Transposon insertion profiling by sequencing (TIPseq) for mapping LINE-1 insertions in the human genome. Mobile DNA. 2019 Mar;10:8 (open access)
Key words: LINE-1, targeted PCR, next generation sequencing

13. Sugimoto K, Ito T, Woo J, Tully E, Sato K, Orita H, Brock MV, Gabrielson E. Prognostic impact of phosphorylated discoidin domain receptor-1 in esophageal cancer. J Surg Res. 2019 Mar;235:479-86.
Key words: Discoid domain receptor-1, esophageal squamous cell carcinoma, phosphorylation, prognosis, receptor tyrosine kinase
PMID: 30691832

14. Vizcaino MA, Palsgrove DN, Yuan M, Giannini C, Cabrera-Aldana EE, Pallavajjala A, Burger PC, Rodriguez FJ. Granular cell astrocytoma: an aggressive IDH-wildtype diffuse glioma with molecular genetic features of primary glioblastoma. Brain Pathol. 2019 Mar;29(2):193-204.
Key words: TERT, GBM, granular cell, IDH-wildtype, astrocytoma, diffuse glioma, glioblastoma

15. Wang C, Rosner GL, Roden RBS. A Bayesian design for phase I cancer therapeutic vaccine trials. Stat Med. 2019 Mar 30;38(7):1170-89.
Key words: Bayesian, HPV, phase I, cancer therapeutic vaccine, clinical trial
PMID: 30368868

1. Allison DB, Rooper LM, Mustafa S, Maleki Z, Wakely PE Jr, Ali SZ. Cytopathologic characteristics of HPV-related small cell carcinoma of the oropharynx. Cancer Cytopathol. 2019 Feb;127(1):35-43.
Key words: cytopathology, head and neck cancer, human papillomavirus, small cell carcinoma, squamous cell carcinoma
PMID: 30468701

2. De Marchi F, Haley L, Fryer H, Ibrahim J, Beierl K, Zheng G, Gocke CD, Eshleman JR, Belchis D, Illei P, Lin MT. Clinical validation of coexisting activating mutations within EGFR, mitogen-activated protein kinase, and phosphatidylinositol 3-kinase pathways in lung cancers. Arch Pathol Lab Med. 2019 Feb;143(2):174-82.
Key words: coexisting mutations, KRAS, EGFR, lung cancers, quality assessment

3. Goel R, Patel EU, White JL, Chappidi M, Ness PM, Cushing MM, Takemoto C, Shaz BH, Frank SM, Tobian AAR. Factors associated with red blood cell, platelet, and plasma transfusions among inpatient hospitalizations: a nationally representative study in the United States. Transfusion. 2019 Feb;59(2):500-7.
Key words: transfusion, platelet, hospitalization

4. Homsy J, King R, Bannink F, Namukwaya Z, Vittinghof E, Amone A, Ojok F, Rukundo G, Amama S, Etima J, Matovu J, Weissglas F, Ojom L, Atim P, Darbes L, Byamugisha J, Rutherford G, Katabira E, Fowler MG; PRIMAL Study Team. Primary HIV prevention in pregnant and lactating Ugandan women: A randomized trial. PLoS One. 2019 Feb 25;14(2):e0212119.
Key words: Uganda, HIV, pregnancy

5. Rooper LM, Jo VY, Antonescu CR, Nose V, Westra WH, Seethala RR, Bishop JA. Adamantinoma-like Ewing sarcoma of the salivary glands: a newly recognized mimicker of basaloid salivary carcinomas. Am J Surg Pathol. 2019 Feb;43(2):187-94.
Key words: Ewing sarcoma, salivary glands, salivary carcinoma

6. Sadasivam M, Noel S, Lee SA, Gong J, Allaf ME, Pierorazio P, Rabb H, Hamad ARA. Activation and proliferation of PD-1+ kidney double-negative T cells is dependent on nonclassical MHC proteins and IL-2. J Am Soc Nephrol. 2019 Feb;30(2):277-92. (cover article)
Key words: T cells, immunology, ischemia-reperfusion

PMID: 30622155

7. Shaukat I, Kern JJ, Höti N, Zhang H, Li J, Zheng G, Askin F, Gabrielson E3 Li QK. Detection of RAS and RAS-associated alterations in primary lung adenocarcinomas. A correlation between molecular findings and tumor characteristics. Hum Pathol. 2019 Feb;84:18-25.
Key words: EGFR, KRAS, lung adenocarcinomas (ADC), NRAS
PMID: 30266251

8. Yu SH, Maynard JP, Vaghasia AM, De Marzo AM, Drake CG, Sfanos KS. A role for paracrine interleukin-6 signaling in the tumor microenvironment in prostate tumor growth. Prostate. 2019 Feb;79(2):215-22.
Key words: inflammation, interleukin 6, microenvironment, prostate cancer, tumor growth
PMID: 30345534

1. Akshintala VS, Talukdar R, Singh VK, Goggins M. The gut microbiome in pancreatic disease. Clin Gastroenterol Hepatol. 2019 Jan;17(2):290-5.
Key words: Dysbiosis; Intratumoral Bacteria; Microbiome; Pancreatic Cancer; Pancreatitis; Probiotics


2. Bell WR, Meeker AK, Rizzo A, Rajpara S, Rosenthal IM, Flores Bellver M, Aparicio Domingo S, Zhong X, Barber JR, Joshu CE, Canto-Soler MV, Eberhart CG, Heaphy CM. A unique telomere DNA expansion phenotype in human retinal rod photoreceptors associated with aging and disease.Brain Pathology. 2019 Jan;29(1):45-52.
Key words: diabetic retinopathy, glaucoma; retina, rod photoreceptors, telomeres
PMID: 29668072

3. Fogel JM, Sandfort T, Zhang Y, Guo X, Clarke W, Breaud A, Cummings V, Hamilton EL, Ogendo A, Kayange N, Panchia R, Dominguez K, Chen YQ, Eshleman SH. Accuracy of self-reported HIV status among African men and transgender women who have sex with men who were screened for participation in a research study: HPTN 075. AIDS Behav. 2019 Jan;23(1):289-94.
Key words: HIV, self-report, MSM, transgender women, Africa, ART
PMID: 30051192

4. Gelwan E, Zhang ML, Allison DB, Cowan ML, DeLuca J, Fite JJ, Wangsiricharoen S, Williamson B, Zhou A, VandenBussche CJ. Variability among observers utilizing the CellSolutions BestCyte Cell Sorter imaging system for the assessment of urinary tract cytology specimens. J Am Soc Cytopathol. 2019 Jan 1;8(1):18-26.
Key words: cytology, bladder cancer, digital imaging, urine, urothelial carcinoma
No PMID available

5. Hong SM, Noë M, Hruban CA, Thompson ED, Wood LD, Hruban RH. A "clearer" view of pancreatic pathology: a review of tissue clearing and advanced microscopy techniques. Adv Anat Pathol. 2019 Jan;26(1):31-9. (REVIEW)
Key words: pathologic lesions, pancreas, microscopy
PMID: 30256228

6. Isser A, Schneck JP. High-affinity T cell receptors for adoptive cell transfer. J Clin Invest 2019 Jan 2;129(1):69-71.
Key words: T cell receptors, adoptive cell transfer
PMID: 30530992

7. Leiby DA, O'Brien SF, Wendel S, Nguyen ML, Delage G, Devare SG, Hardiman A, Nakhasi HL, Sauleda S, Bloch EM; WPTTID Subgroup on Parasites. International survey on the impact of parasitic infections: frequency of transmission and current mitigation strategies. Vox Sang. 2019 Jan;114(1):17-27.
Key words: Babesia ; Leishmania ; Plasmodium ; Trypanosoma cruzi ; public health; transfusion transmission
PMID: 30523642

8. Matoso A, Epstein JI. Defining clinically significant prostate cancer on the basis of pathological findings. Review. Histopathology. 2019 Jan;74(1):135-45.
Key words: active surveillance, prostate cancer, significant cancer
PMID: 30565298

9. Payer LM, Steranka JP, Ardeljan D, Walker J, Fitzgerald KC, Calabresi PA, Cooper TA, Burns KH. Alu insertion variants alter mRNA splicing. Nucleic Acids Res. 2019 Jan 10;47(1):421-31.
Key words: mRNA splicing, Alu retrotransposons

PMID: 30418605

10. Rodriguez FJ, Brosnan-Cashman JA, Allen SJ, Vizcaino MA, Giannini C, Camelo-Piragua S, Webb M, Matsushita M, Wadhwani N, Tabbarah A, Hamideh D, Jiang L, Chen L, Arvanitis LD, Alnajar HH, Barber JR, Rodríguez-Velasco A, Orr B, Heaphy CM. Alternative lengthening of telomeres, ATRX loss and H3-K27M mutations in histologically defined pilocytic astrocytoma with anaplasia. Brain Pathol. 2019 Jan;29(1):126-40.
Key words: ATRX, H3-K27M, alternative lengthening of telomeres, glioma, pilocytic astrocytoma
PMID: 30192422

11. Simner PJ, Bergman Y, Trejo M, Roberts AA, Marayan R, Tekle T, Campeau S, Kazmi A, Bell D, Lewis S, Tamma PD, Humphries R, Hindler JA. Two-Site evaluation of the colistin broth disk elution test to determine colistin in vitro activity against gram-negative bacilli. J Clin Microbiol. 2019 Jan;57(2):e01163-18.
Key words: colistin broth disk elution, antimicrobial susceptibility testing, colistin, method
PMID: 30282791

12. Tamma PD, Fan Y, Bergman Y, Pertea G, Kazmi AQ, Lewis S, Carroll KC, Schatz MC, Timp W, Simner PJ. Applying rapid whole-genome sequencing to predict phenotypic antimicrobial susceptibility testing results among carbapenem-resistant Klebsiella pneumoniae clinical isolates. Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e01923-18. doi: 10.1128/AAC.01923-18. Print 2019 Jan.
Key words: Illumina; WGS; antibiotic resistance; antimicrobial resistance

13. Wang Y, Xu J, Chang L, Meyers CA, Zhang L, Broderick K, Lee M, Peault B, James AW. Relative contributions of adipose-resident CD146+ pericytes and CD34+ adventitial progenitor cells in bone tissue engineering. NPJ Regen Med. 2019 Jan 7;4:1. doi: 10.1038/s41536-018-0063-2. eCollection 2019.
Key words: Mesenchymal stem cell, perivascular stem cell, bone tissue, bone repair, bone regeneration
PMID: 30622740

14. Weimer A, Tagny CT, Tapko JB, Gouws C, Tobian AAR, Ness PM, Bloch EM. Blood transfusion safety in sub-Saharan Africa: A literature review of changes and challenges in the 21st century. Transfusion. 2019 Jan;59(1):412-27.
PMID: 30615810

15. Zhou AG, Salles DC, Samarska IV, Epstein JI. How are Gleason Scores categorized in the current literature: an analysis and comparison of articles published in 2016-2017. Eur Urol. 2019 Jan;75(1):25-31.
Key words: Gleason score, prostate cancer grading, grade groups
PMID: 30057131

1. Cloutier J, Thompson ED, Cimino-Mathews A, Rooper LM, Matoso A, Argani P. Metastatic breast cancer simulating well-differentiated neuroendocrine neoplasms of visceral organs. Hum Pathol. 2018 Dec;82:76-86.
Key words: breast carcinoma, metastastatic, endocrine
PMID: 30031098

2. Gehrie EA. Atypical bacterial growth within units of platelets challenges transfusion medicine dogma. J Clin Microbiol. 2018 Nov 27;56(12). pii: e01363-18. doi: 10.1128/JCM.01363-18.
Key words: bacterial growth, platelets, transfusion medicine
No PMID available

3. Hickey JW, Isser AY, Vicente FP, Warner SB, Mao HQ, Schneck JP. Efficient magnetic enrichment of antigen-specific T cells by engineering particle properties. Biomaterials. 2018 Dec;187:105-16.
Key words: artificial antigen-presenting cells, immunotherapy, magnetic enrichment, nanoparticles, T cells
PMID: 30312851

4. Jaiswal AK, Sadasivam M, Hamad ARA. Unexpected alliance between syndecan-1 and innate-like T cells to protect host from autoimmune effects of interleukin-17. World J Diabetes. 2018 Dec 15;9(12):220-5.
Key words: interleukin-17, natural killer T 17 cells, natural killer T cell, syndecan-1

5. Montgomery E, Arnold CA, Lam-Himlin D, Salimian K, Waters K. Some observations on Barrett esophagus and associated dysplasia. Ann Diagn Pathol. 2018 Dec;37:75-82.
Key words: Barrett esophagus, dysplasia
PMID: 30312881

6. Palsgrove DN, Brosnan-Cashman JA, Giannini C, Raghunathan A, Jentoft M, Bettegowda C, Gokden M, Lin D, Yuan M, Lin MT, Heaphy CM, Rodriguez FJ. Subependymal giant cell astrocytoma-like astrocytoma: a neoplasm with a distinct phenotype and frequent neurofibromatosis type-1-association. Mod Pathol. 2018 Dec;31(12):1787-800.
Key words: astrocytoma, neoplasm, neurofibromatosis
PMID: 29973652

7. Paulk A, Giannico G, Epstein JI. PIN-like (Ductal) adenocarcinoma of the prostate. Am J Surg Pathol 2018 Dec;42(12):1693-1700.
Key words: ductal adenocarcinoma, Gleason grade, prostatic adenocarcinoma
PMID: 30138215

8. Pisanic TR 2nd, Cope LM, Lin SF, Yen TT, Athamanolap P, Asaka R, Nakayama K, Fader AN, Wang TH, Shih IM, Wang TL. Methylomic analysis of ovarian cancers identifies tumor-specific alterations readily detectable in early precursor lesions. Clin Cancer Res. 2018 Dec 15;24(24):6536-47.
Key words: methylation, ovarian cancer, endometrioid cancer, early detection

8. Qiu J, Peng S, Ma Y, Yang A, Farmer E, Cheng MA, Roden RBS, Wu TC, Chang YN, Hung CF. Epithelial boost enhances antigen expression by vaccinia virus for the generation of potent CD8+ T cell-mediated antitumor immunity following DNA priming vaccination. Virology. 2018 Dec;525:205-15.
Key words: PMID: Human papillomavirus; Pre-clinical model; TA-HPV; Therapeutic HPV vaccine; pNGVL4a-Sig/E7(detox)/HSP70
PMID: 30296681

9. Samaan S, Quddus MR, Matoso A. "Man in Istanbul" lesions of the urinary tract (known entities in an unusual context): melanoma, carcinoid tumors, epithelioid angiosarcoma. Surg Pathol Clin. 2018 Dec;11(4):825-36. Review
Key words: bladder, carcinoid tumor, epithelioid angiosarcoma, kidney, melanoma
PMID: 30447844

10. Waters KM, Salimian KJ, Voltaggio L, Montgomery EA. Refined criteria for separating low-grade dysplasia and nondysplastic Barrett esophagus reduce equivocal diagnoses and improve prediction of patient outcome: A 10-Year review. Am J Surg Pathol. 2018 Dec;42(12):1723-9.
Key words: dysplasia, Barrett esophagus, patient outcome

PMID: 30234520

1. Argani P, Reuter VE, Kapur P, Brown JE, Sung YS, Zhang L, Williamson R, Francis G, Sommerville S, Swanson D, Dickson BC, Antonescu CR. Novel MEIS1-NCOA2 gene fusions define a distinct primitive spindle cell sarcoma of the kidney. Am J Surg Pathol. 2018 Nov;42(11):1562-70.
Key words: Kidney, sarcoma, translocation
PMID: 30179902

2. Asnaghi L, White DT, Key N, Choi J, Mahale A, Alkatan H, Edward DP, Elkhamary SM, Al-Mesfer S, Maktabi A, Hurtado CG, Lee GY, Carcaboso AM, Mumm JS, Safieh LA, Eberhart CG. ACVR1C/SMAD2 signaling promotes invasion and growth in retinoblastoma. Oncogene. 2018 Nov 6. doi: 10.1038/s41388-018-0543-2.
Key words: retinoblastoma, optic nerve, signaling
PMID: 30401983

3. Hutchings D, Waters KM, Weiss MJ, Wolfgang CL, Makary MA, He J, Cameron JL, Wood LD, Hruban RH. Cancerization of the pancreatic ducts: demonstration of a common and under-recognized process using immunolabeling of paired duct lesions and invasive pancreatic ductal adenocarcinoma for p3 and Smad4 expression. Am J Surg Pathol. 2018 Nov;42(11):1556-61.
Key words: pancreatic ducts, duct lesions, pancreatic adenocarcinoma
PMID: 30212393

4. Kageyama Y, Saito A, Pletnikova O, Rudow GL, Irie Y, An Y, Murakami K, Irie K, Resnick SM, Fowler DR, Martin LJ, Troncoso JC. Amyloid ? toxic conformer has dynamic localization in the human inferior parietal cortex before amyloid ? plaques form. Sci Rep. 2018 Nov 15;8(1):16895.
Key words: glymphatic system, microvesicle, aging, astrocytes, Alzheimer's disease, lysosome

5. Khararjian A, Mathew P, Choudhary A, Baras A. Cost effectiveness of intraoperative gross examination in colorectal resections: a retrospective review of 200 consecutive cases. Arch Pathol Lab Med. 2018 Nov;142(11):1403-6.
Key words: cost effectiveness, colorectal resection, retrospective review
PMID: 29902068

6. Li G, Adams E, Eshleman JR, Eberhart CG. No BRAF V600E mutation identified in 28 periocular pyogenic granuloma. Ophthalmic Plast Reconstr Surg. 2018 Nov/Dec;34(6):525-7.
Key words: mutation, periocular pyogenic granuloma
PMID: 29406329

7. Montgomery EA. Diagnostic histochemistry of soft tissue lesions. Semin Diagn Pathol. 2018 Nov;35(6):399-406.
Key words: histochemistry, mucin stains, periodic acid-Schiff stains, soft tissue lessions, trichrome stains
No PMID available

8. Murdock T, Orr B, Allen S, Ibrahim J, Sharma R, Ronnett BM, Rodriguez GJ. Central Nervous System-type Neuroepithelial tumors and tumor-like proliferations developing in the gynecologic tract and pelvis : clinicopathologic analysis of 23 Cases. Am J Surg Pathol 2018 Nov;42(11):1429-44.
Key words: central nervous system tumors, central type primitive neuroectodermal tumor, gynecologic tract, pelvis


9. Patel H, Gupta M, Tosoian, JJ, Carter HB, Partin AW, Epstein JI. Subtyping the risk of intermediate-risk prostate cancer for active surveillance based on adverse pathology at radical prostatectomy. J Urol. 2018 Nov;200(5):1068-74.
Key words: active surveillance, prostate adenocarcinoma, Gleason grade
PMID: 29673946

10. Pletnikova O, Kageyama Y, Rudow G, LaClair KD, Albert M, Crain BJ, Tian J, Fowler D, Troncoso JC. The spectrum of preclinical Alzheimer's disease pathology and its modulation by ApoE genotype. Neurobiol Aging. 2018 Nov;71:72-80.
Key words: dementia, A? amyloid, PyroGlu-A?, tau, neurofibrillary tangles
PMID: 30099348

11. Tamma PD, Simner PJ. Phenotypic detection of carbapenemase-producing organisms from clinical isolates. J Clin Microbiol. 2018 Nov;56(11):e01140-18.
Key words: phenotype, carbapenemase, clinical isolates
PMID: 30158194

12. Tregnago AC, Epstein JI. Skene's glands adenocarcinoma: a series of 4 cases. Am J Surg Pathol. 2018 Nov;42(11):1513-21.
Key words: skenes gland, periurethral gland, prostate adenocarcinoma

PMID: 29901570

13. Yang JM, Bhattacharya S, West-Foyle H, Hung CH, Wu TC, Iglesias PA, Huang CH. Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation. Nat Commun. 2018 Nov 07; 9(1):article # 4673.
Key words: cancer, Ras-ERK signaling, single cell imaging, synthetic biology, optogenetics
PMID: 30405112

14. Yang W, Ao M, Hu Y, Li QK, Zhang H. Mapping the O-glycoproteome using site-specific extraction of O-linked glycopeptides (EXoO). Mol Syst Biol 2018 Nov 20;14(11):e8486.
Key words: O?GalNAc; O?linked; glycoproteomics; glycosylation; site?specific
PMID: 30459171

15. Zhang Y, Sivay MV, Hudelson SE, Clarke W, Breaud A, Wang J, Piwowar-Manning E, Agyei Y, Fogel JM, Hamilton EL, Selin A, MacPhail C, Kahn K, Gómez-Olivé FX, Hughes JP, Pettifor A, Eshleman SH. Antiretroviral drug use and HIV drug resistance among young women in rural South Africa: HPTN 068. J Acquir Immune Defic Syndr 2018 Nov 1;79(3):315-22.
Key words: HIV, antiretroviral, resistance, South Africa


1. Alharbi AM, De Marzo AM, Hicks JL, Lotan TL, Epstein JI. Prostatic adenocarcinoma with focal pleomorphic giant cell features: a series of 30 cases. Am J Surg Pathol 2018 Oct;42(10):1286-96.
Key words: prostate adenocarcinoma, prostate carcinoma, PSA, nkx3.1
PMID: 29944471

2. Allison DB, VandenBussche CJ, Rooper LM, Wakely PE Jr, Rossi ED, Faquin WC, Ali SZ. Nodular fasciitis of the parotid gland: A challenging diagnosis on FNA. Cancer Cytopathol 2018 Oct;126(10):872-80.
Key words: fasciitis, parotid gland, fine needle aspiration
PMID: 30311731

3. Argani P. A Molecular marker for eosinophilic solid and cystic renal cell carcinoma. Eur Urol. 2018 Oct;74(4):487-8.
Key words: renal, tuberous sclerosis, carcinoma

4. Chang L, Zhang L, Xu J, Meyers CA, Li Z, Yan N, Zou E, James AW. Lineage-specific Wnt reporter elucidates mesenchymal Wnt signaling during bone repair. Am J Pathol 2018 Oct;188(10):2155-63. (short communication)
Key words: skeletal development, bone repair, Wnt signaling
PMID: 30031726

5. Debeljak M, Noë M, Riel SL, Haley LM, Norris AL, Anderson DA, Adams EM, Suenaga M, Beierl KF, Lin MT, Goggins MG, Gocke CD, Eshleman JR. Validation strategy for ultrasensitive mutation detection. Mol Diagn Ther. 2018 Oct;22(5):603-11.
Key words: mutation detection, validation strategy
PMID: 29974360

6. Illei PB, Wong W, Wu N, Chu L, Gupta R, Schulze K, Gubens MA. ALK testing trends and patterns among community practices in the United States. JCO Precision Oncology 2018 :2, 1-11. DOI: 10.1200/PO.18.00159
Key words: ALK testing, community practices
No PMID available

7. Meyer CA, Xu J, Asatrian G, Ding C, Shen J, Broderick K, Ting K, Soo C, Peault B, James AW. WISP-1 drives bone formation at the expense of fat formation in human perivascular stem cells. Scientific Reports. 2018 Oct; 8:15618.
Key words: bone formation, fat formation, human perivascular stem cells, WISP-1

8. Nix JS, Haffner MC, Ahsan S, Hicks J, De Marzo AM, Blakeley J, Raabe EH, Rodriguez FJ. Malignant peripheral nerve sheath tumors show decreased global DNA methylation. J Neuropathol Exp Neurol. 2018 Oct 1;77(10):958-63.
Key words: 5-hydroxymethylcytosine, 5-methylcytosine, epigenetics, malignant nerve sheath tumors, methylation
PMID: 30169729

9. Osmani L, Askin F, Gabrielson E, Li QK. Current WHO guidelines and the critical role of immunohistochemical markers in the subclassification of non-small cell lung carcinoma (NSCLC): Moving from targeted therapy to immunotherapy. Semin Cancer Biol. 2018 Oct;52(Pt 1):103-9.
Key words: EGFR mutations; Fine needle aspiration (FNA) biopsy; Non-small cell lung carcinoma (NSCLC); PD-L1 immunotherapy; Targeted therapy
PMID: 29183778

10. Rock C, Anderson M, Lewis S, Scheeler V, Nowakowski E, Hsu YJ, Milstone AM, Carroll KC, Maragakis LL, Simner PJ; CDC Prevention Epicenters Program. Comparison of nylon-flocked swab and cellulose sponge methods for carbapenem-resistant Enterobacteriaceae and gram-negative organism recovery from high-touch surfaces in patient rooms. Infect Control Hosp Epidemiol. 2018 Oct;39(10):1257-61.
Key words: nylon-flocked swab, cellulose sponge, carbapenem-resistant Enterobacteriaceae, patient rooms

PMID: 30152307

11. Sun Y, Argani P, Tickoo SK, Epstein JI. Acquired cystic disease-associated renal cell carcinoma (ACKD-RCC)-like cysts. Am J Surg Pathol. 2018 Oct;42(10):1396-1401.
Key words: renal cell carcinoma, renal cysts, end stage renal disease
PMID: 30001236

12. Zhang L, Chang L, Xu J, Meyers CA, Yan N, Zou E, James AW. Lineage specific Wnt reporter elucidates mesenchymal Wnt signaling during bone repair. Am J Pathol. 2018 Oct;188(10):2155-63.
Key words: Wnt signaling, bone repair, mesenchyma

PMID: 30031726

1. Brosnan-Cashman JA, Yuan M, Graham MK, Rizzo AJ, Myers KM, Davis C, Zhang R, Esopi DM, Raabe EH, Eberhart CG, Heaphy CM, Meeker AK. ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner. PLoS One. 2018 Sep 18;13(9):e0204159. eCollection 2018.
Key words: cancer, telomeres, alternative lengthening of telomeres (ALT), glioma, CRISPR
PMID: 30226859

2. Bynum JP, Zachary A, Ness PM, Luo X, Bagnasco S, King KE, Segev DL, Orandi BJ, Warren DS, Fuller A, Uglik K, Montgomery R, Tobian AAR. Transfusion of leukoreduced blood products and risk of antibody-mediated rejection of renal allografts. Transfusion. 2018;58:1951-7.
Key words: blood products, renal allografts, transfusion
PMID: 30171817

3. Canto MI, Almario JA, Schulick RD, Yeo CJ, Klein A, Blackford A, Shin EJ, Sanyal A, Yenokyan G, Lennon AM, Kamel I, Fishman EK, Wolfgang C, Weiss M, Hruban RH, Goggins MG. Risk of neoplastic progression in high-risk individuals undergoing long-term surveillance for pancreatic cancer. Gastroenterology. 2018 Sep;155(3):740-51.
Key words: early detection, familial pancreatic cancer, IPMN, panIN-3
PMID: 29803839

4. Cheng MA, Farmer E, Huang C, Lin J, Hung CF, Wu TC. Therapeutic DNA vaccines for human papillomavirus and associated diseases. Hum Gene Ther. 2018 Sep;29(9):971-96. (review)
Key words: therapeutic DNA vaccine, human papillomavirus
PMID: 29316817

5. Felsenstein M, Noë M, Masica DL, Hosoda W, Chianchiano P, Fischer CG, Lionheart G, Brosens LAA, Pea A, Yu J, Gemenetzis G, Groot VP, Makary MA, He J, Weiss MJ, Cameron JL, Wolfgang CL, Hruban RH, Roberts NJ, Karchin R, Goggins MG, Wood LD. IPMNs with co-occurring invasive cancers: neighbours but not always relatives. Gut 2018 Sep;67(9):1652-62.
Key words: cancer genetics, carcinogenesis, molecular genetics, mutations, pancreatic cancer
PMID: 29500184

6. Goel R, Patel EU, Cushing MM, Frank SM, Ness PM, Takemoto CM, Vasovic LV, Sheth S, Nellis ME, Shaz B, Tobian AAR. Association of perioperative red blood cell transfusions with venous thromboembolism in a North American registry. JAMA Surg 2018 Sep 1;153(9):826-33.
Key words: red blood cell transfusions, venous thromboembolism
PMID: 29898202

7. Hassan O, Matoso A. Clinical significance of subtypes of Gleason pattern 4 prostate cancer. Transl Androl Urol. 2018 Sep;7(Suppl 4):S477-S483.
Key words: prostate cancer, cribriform, glomeruloid, grade group, Gleason grade
PMID: 30363452

8. Jaiswal AK, Sadasivam M, Archer NK, Miller RJ, Dillen CA, Ravipati A, Park PW, Chakravarti S, Miller LS, Hamad ARA. Syndecan-1 regulates psoriasiform dermatitis by controlling homeostasis of IL-17-Producing ?? T cells. J Immunol. 2018 Sep 15;201(6):1651-61.
Key words: sdc1, T??17 cells, Interleukin-17, thymus

9. Jaquenod De Giusti C, Roman B, Das S. The influence of MicroRNAs on mitochondrial calcium. Front Physiol. 2018 Sep 21;9:1291. eCollection 2018.
Key words: MitomiR, heart failure, miRNA, microRNA, mitochondria, mitochondrial calcium
PMID: 30298016

10. Palsgrove DN, Li Y, Pratilas CA, Lin MT, Pallavajjalla A, Gocke C, De Marzo AM, Matoso A, Netto GJ, Epstein JI, Argani P. Eosinophilic solid and cystic (ESC) renal cell carcinomas harbor TSC mutations: molecular analysis supports an expanding clinicopathologic spectrum. Am J Surg Pathol. 2018 Sep;42(9):1166-81.
Key words: kidney, TSC, mutation

PMID: 29975249

11. Simner PJ, Miller HB, Breitwieser FP, Pinilla Monsalve G, Pardo CA, Salzberg SL, Sears CL, Thomas DL, Eberhart CG, Carroll KC. Development and optimization of metagenomic next-generation sequencing methods for cerebrospinal fluid diagnostics. J Clin Microbiol. 2018 Aug 27;56(9). pii: e00472-18. doi: 10.1128/JCM.00472-18. Print 2018 Sep.
Key words: CSF, metagenomics, next-generation sequencing
PMID: 29976594

12. Sokoll LJ, Mangold L, Mohr P, Dua R, Partin AW. High "phi"ve. J Appl Lab Med. 2018 Sep 3:333-5. (Letter)
Key words: prostate health index, prostate cancer, prostate-specific antigen
No PMID available

1. Argani P, Pawel B, Szabo S, Reyes-Múgica M, Timmons C, Antonescu CR. Diffuse strong BCOR immunoreactivity is a sensitive and specific marker for clear cell sarcoma of the kidney (CCSK) in pediatric renal neoplasia. Am J Surg Pathol. 2018 Aug;42(8):1128-31. Letter to Editor
Key words: pediatric, renal, clear cell sarcoma, BCOR

2. Cottrell TR, Thompson ED, Forde PM, Stein JE, Duffield AS, Anagnostou V, Rekhtman N, Anders RA, Cuda JD, Illei PB, Gabrielson E, Askin FB, Niknafs N, Smith KN, Velez MJ, Sauter JL, Isbell JM, Jones DR, Battafarano RJ, Yang SC, Danilova L, Wolchok JD, Topalian SL, Velculescu VE, Pardoll DM, Brahmer JR, Hellmann MD, Chaft JE, Cimino-Mathews A, Taube JM. Pathologic features of response to neoadjuvant anti-PD-1 in resected non-small cell lung carcinoma: a proposal for quantitative immune-related pathologic response criteria (irPRC). Ann Oncol. 2018 Aug 1;29(8):1853-60.
Key words: anti-PD-1, non-small cell lung carcinoma, pathologic response

3. Hassan O, Epstein JI. The clinical significance of a small component of choriocarcinoma in testicular mixed germ cell tumor (MGCT). Am J Surg Pathol. 2018 Aug;42(8):1113-20.
Key words: choriocarcinoma, testicular neoplasms, syncytiotrophoblasts
PMID: 29794869

4. Kim YS, Park HJ, Park JH, Hong EJ, Jang GY, Jung ID, Han HD, Lee SH, Vo MC, Lee JJ, Yang A, Farmer E, Wu TC, Kang TH, Park YM. A novel function of API5 (apoptosis inhibitor 5), TLR4-dependent activation of antigen presenting cells. OncoImmunology. 15 Aug 2018. DOI: 10.1080/2162402X.2018.1472187
Key words: API5, dendritic cells, cancer vaccines, adjuvants, TLR4
no PMID available

5. Mannan AASR, Vieth M, Khararjian A, Khandakar B, Lam-Himlin D, Heydt D, Bhaijee F, Venbrux HJ, Byrnes K, Voltaggio L, Barker N, Yuan S, Montgomery EA. The outlet patch: gastric heterotopia of the colorectum and anus. Histopathology. 2018 Aug;73(2):220-9.
Key words: gastric heterotopia; heterotopia; heterotopic gastric mucosa; pyloric gland adenoma
PMID: 29667709

6. Macgregor-Das AM, Das S. A microRNA's journey to the center of the mitochondria. Am J Physiol Heart Circ Physiol. 2018 Aug 1;315(2):H206-15.
Key words: MicroRNA, Mitochondria, MitomiR, mitochondrial transport, heart
PMID: 29570349

7. Meyers CA, Shen J, Lu A, James AW. WNT16 induces proliferation and osteogenic differentiation of human perivascular stem cells. J Orthop. 2018 Aug 16;15(3):854-7.
Key words: mesenchymal stem cell, stem cell differentiation, bone, osteogenesis, Wnt signaling

8. Song KH, Kim JH, Lee YH, Bae HC, Lee HJ, Woo SR, Oh SJ, Lee KM, Yee C, Kim BW, Cho H, Chung EJ, Chung JY, Hewitt SM, Chung TW, Ha KT, Bae YK, Mao CP, Yang A, Wu TC, Kim TW. Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance. J Clin Invest. 2018 Aug 31;128(9) 4098-144.
Key words: cancer, immunology, oncology
PMID: 30124467

9. Wang JW, Wu WH, Huang TC, Wong M, Kwak K, Ozato K, Hung CF, Roden RBS. Roles of Fc domain and exudation in L2 antibody-mediated protection against human Papillomavirus. J Virol. 2018 Jul 17;92(15). pii: e00572-18. doi: 10.1128/JVI.00572-18. Print 2018 Aug 1.
Key words: Fc; FcRn; L2 protein; TRIM21; antibody-mediated protection; cross-protection; human papillomavirus; humoral immunity; monoclonal antibody; neutralizing antibodies

1. Allison DB, Sharma R, Cowan ML, VandenBussche CJ. Evaluation of Sienna cancer diagnostics hTERT antibody on 500 consecutive urinary tract specimens. Acta Cytol 2018 July-Aug;62(4):302-10.
Key words: urinary tract, bladder cancer, urothelial cancer, cytology, cytopathology
PMID: 29874657

2. Cowan ML, VandenBussche CJ. The Paris System for Reporting Urinary Cytology: early review of the literature reveals successes and rare shortcomings. J Am Soc of Cytopathol. 2018 Jul-Aug;7(4):185-194.
Key words: the Paris system; urinary tract; cytology; cytopathology
PMID: 28272842

3. Fite JJ, Ali SZ, VandenBussche CJ. Fine?needle aspiration of a pancreatic neuroendocrine tumor with prominent rhabdoid features. Diagn Cytopathol. 2018 Jul;46(7):600-3.
Key words: pancreas, pancreatic neuroendocrine tumor, rhabdoid, fine needle aspiration
No PMID available

4. Hata T, Suenaga M, Marchionni L, Macgregor-Das A, Yu J, Shindo K, Tamura K, Hruban RH, Goggins M. Genome-wide somatic copy number alterations and mutations in high-grade pancreatic intraepithelial neoplasia. Am J Pathol. 2018 Jul;188(7):1723-33.
Key words: genome, pancreatic intraepithelial neoplasia, copy number
PMID: 29684357

5. Hu Y, Shah P, Clark DJ, Ao M, Zhang H. Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides. Anal Chem. 2018 Jul 3;90(13):8065-8071.
Key words: glycoproteins, glycoproteomics, proteomics, software tool, mass spectrometry
PMID: 29741879

6. Kwon R, Allen LA, Scherer LD, Thompson JS, Abdel-Maksoud MF, McIlvennan CK, Matlock DD. The effect of total cost information on consumer treatment decisions: an experimental survey. Medical Decision Making. 2018 Jul;38(5):584-592.
Key words: decision aids, end-of-life care, ethics, health care costs, patient decision making
PMID: 29847252

7. Martin LJ, Chang Q. DNA damage response and repair, DNA methylation, and cell death in human neurons and experimental animal neurons are different. J Neuropathol Exp Neurol. 2018 Jul 1;77(7):636-55.
Key words: Alzheimer Disease, amyotrophic lateral sclerosis (ALS), apoptosis, cerebral ischemia, excitotoxicity
PMID: 29788379

8. Noë M, Rezaee N, Asrani K, Skaro M, Groot VP, Wu PH, Olson MT, Hong SM, Kim SJ, Weiss MJ, Wolfgang CL, Makary MA, He J, Cameron JL, Wirtz D, Roberts NJ, Offerhaus GJA, Brosens LAA, Wood LD, Hruban RH. Immunolabeling of cleared human pancreata provides insights into three-dimensional pancreatic anatomy and pathology. Am J Pathol. 2018 Jul;188(7):1530-5.
Key words: endometriosis, pathogenesis, mutation, genetics
PMID: 29684363

9. Patel EU, Gaydos CA, Packman ZR, Quinn TC, Tobian AAR. Prevalence and correlates of Trichomonas vaginalis infection among men and women in the United States. Clin Infect Dis. 2018 Jul;67(2):211-7.
Key words: Trichomonas vaginalis, infection
PMID: 29554238

10. Patil PA, Blakely AM, Lombardo KA, Machan JT, Miner TJ, Wang LJ, Marwaha AS, Matoso A. Expression of PD-L1, indoleamine 2,3-dioxygenase and the immune microenvironment in gastric adenocarcinoma. Histopathology 2018 Jul;73(1):124-36
Key words: gastric adenocarcinoma, immune microenvironment, indoleamine dioxygenase, programmed cell death ligand 1, tumour-infiltrating lymphocyte

11. PMID: 29489025
Ware AD, Birkness J, Duffield AS, Gocke CD. Molecular evidence of JAK2 p.V617F mutated pure erythroid leukemia arising from polycythemia vera. Virchows Arch. 2018 Jul;473(1):131-5.
Key words: acute leukemia, polycythemia vera, flow cytometry, molecular pathology
PMID: 29611054

12. Yang Z, Epstein JI. Urothelial carcinoma in situ of the bladder with glandular differentiation: report of 92 cases. Am J Surg Pathol 2018 Jul;42(7):971-6.
Key words: bladder carcinoma, urothelial carcinoma, bladder adenocarcinoma https://insights.ovid.com/pubmed?pmid=29683821
PMID: 29683821

13. Yu Y, Suryo Rahmanto Y, Lee MH, Wu PH, Phillip JM, Huang CH, Vitolo MI, Gaillard S, Martin SS, Wirtz D, Shih IM, Wang TL. Inhibition of ovarian tumour cell invasiveness by targeting SYK in tyrosine kinase signaling pathway. Oncogene. 2018 Jul;37(28):3778-89.
Key words: chemoresistance, ovarian cancer, metastasis, invasion, spleen tyrosine kinase
PMID: 29643476

14. Zheng G, Streiff MB, Takemoto CM, Bynum J, Gelwan E, Jani J, Kickler TS. The Clinical Utility of the Heparin Neutralization Assay in the Diagnosis of Heparin-Induced Thrombocytopenia. Clin Appl Thromb Hemost. 2018 Jul;24(5):749-54.
PMID: 28774196

1. Adler BL, Pezhouh MK, Kim A, Luan L, Zhu Q, Gani F, Yarchoan M, Chen J, Voltaggio L, Parian A, Lazarev M, Lauwers GY, Pawlik TM, Montgomery EA, Jaffee E, Le DT, Taube JM, Anders RA. Histopathological and immunophenotypic features of ipilimumab-associated colitis compared to ulcerative colitis. J Intern Med. 2018 Jun;283(6):568-77.
Key words: colitis, immunotherapy, inflammatory bowel disease, ipilimumab
PMID: 29464806

2. Clark DJ, Hu Y, Bocik W, Chen L, Schnaubelt M, Roberts R, Shah P, Whiteley G, Zhang H. Evaluation of NCI-7 cell line panel as a reference material for clinical proteomics. J Proteome Res. 2018 June;17(6):2205-15.
Key words: Cancer, proteomics, phosphorylation, NCI-7 cells, mass spectrometry
PMID: 29718670

3. Haffner MC, Guner G, Taheri D, Netto GJ, Palsgrove DN, Zheng Q, Guedes LB, Kim K, Tsai H, Esopi DM, Lotan TL, Sharma R, Meeker AK, Chinnaiyan AM, Nelson WG, Yegnasubramanian S, Luo J, Mehra R, Antonarakis ES, Drake CG, De Marzo AM. Comprehensive Evaluation of Programmed Death-Ligand 1 Expression in Primary and Metastatic Prostate Cancer. Am J Pathol. 2018 Jun;188(6):1478-85.
Key words: Prostate cancer, PD-L1, immune oncology, metastases
PMID: 29577933

4. Hassan O, han M, Zhou A, Paulk A, Sun Y, Al-Harbi A, Alraijal A, Baptista Dos Santos F, Epstein JI. Incidence of extra-prostatic extension at radical prostatectomy with pure Gleason score 3+3=6 (Grade Group 1) cancer: Implications for whether Gleason score 6 prostate cancer should be renamed as "not cancer" and for selection criteria for active surveillance. J Urol 2018 Jun;199(6):1482-7.
Key words: radical prostatectomy, prostate adenocarcinoma, stage

PMID: 29154905

5. Lai S, Heaphy CM, Rizzo AJ, Celentano DD, Gerstenblith G, Li J, Kickler TS, Lai H. Cocaine use may induce telomere shortening in individuals with HIV infection. Prog Neuropsychopharmacol Biol Psychiatry 2018 Jun 8;84(Pt A):11-7.
Key words: cocaine, telomere, HIV infection
PMID: 29410247

6. Matoso A, Khandakar B, Yuan S, Wu T, Wang LJ, Lombardo KA, Mangray S, Mannan AASR, Yakirevich E. Spectrum of findings in orchiectomy specimens of persons undergoing gender confirmation surgery. Hum Pathol. 2018 Jun;76:91-9.
Key words: cytomegaly, Leydig cells, orchiectomy, testes histopathology, transgender, transsexual
PMID: 29555572

7. Maughan BL, Guedes LB, Boucher K, Rajoria G, Liu Z, Klimek S, Zoino R, Antonarakis ES, Lotan TL. p53 status in the primary tumor predicts efficacy of subsequent abiraterone and enzalutamide in castration-resistant prostate cancer. Prostate Cancer Prostatic Dis. 2018 Jun;21(2):260-8.
Key words: prostate cancer, abiraterone, enzalutamide, primary tumor, p53
PMID: 29302046

8. Pan CC, Tsuzuki T, Morii E, Fushimi H, Chen PC, Epstein J. Whole-exome sequencing demonstrates recurrent somatic copy number alterations and sporadic mutations in specialized stromal tumors of the prostate. Hum Pathol. 2018 Jun;76:9-16.
Key words: prostate, stromal tumors, genetic, molecular
PMID: 29258903

9. Patel EU, Grabowski MK, Eisenberg A, Packman ZR, Gravitt PE, Tobian AAR. Increases in in human papillomavirus vaccination among adolescents and young adults in the United States, 2011-2016. J Infect Dis. 2018 Jun 5;218(1):109-13.
Key words: human papillomavirus, vaccination, adolescents
PMID: 29584878

10. Priore SF, Schwartz LE, Epstein JI. An expanded immunohistochemical profile of osteoclast-rich undifferentiated carcinoma of the urinary tract. Mod Pathol. 2018 Jun;31(6):984-8.
Key words: bladder, urothelial carcinoma, osteoclastic
PMID: 29410491

11. Rosenberg AZ, Wright C, Fox-Talbot K, Rajpurohit A, Williams C, Porter C, Kovbasnjuk O, McCall MN, Shin JH, Halushka MK. xMD-miRNA-seq to generate near in vivo miRNA expression estimates in colon epithelial cells. Sci Rep. 2018 Jun 28;8(1):9783.
Key words: microRNA, colon epithelial cells

12. VandenBussche CJ, Allison DB, Gupta M, Ali SZ, Rosenthal DL. A 20-year and 46,000-specimen journey to Paris reveals the influence of reporting systems and passive peer feedback on pathologist practice patterns. Cancer Cytopathol. 2018 Jun;126(6):381-9.
Key words: urinary tract cytology, bladder cancer, the Paris System for Reporting Urinary Cytology
PMID: 29757495

13. Xing D, Zheng G, Schoolmeester JK, Li Z, Pallavajjala A, Haley L, Conner MG, Vang R, Hung CF, Wu TC, Ronnett BM. Next-generation sequencing reveals recurrent somatic mutations in small cell neuroendocrine carcinoma of the uterine cervix. Am J Surg Pathol. 2018 Jun;42(6):750-60.
Key words: neuroendocrine carcinoma, uterus, cervix
PMID: 29505425

14. Zhang Y, Fogel JM, Guo X, Clarke W, Breaud A, Cummings V, Hamilton EL, Ogendo A, Kayange N, Panchia R, Dominguez K, Chen YQ, Sandfort T, Eshleman SH. Antiretroviral Drug Use and HIV Drug Resistance Among MSM and Transgender Women in Sub-Saharan Africa. AIDS 2018 Jun;32(10):1301-6.
Key words: antiretroviral, resistance, HIV, MSM, transgender, Africa
PMID: 29794492

1. Ames HM, Rooper LM, Laterra JJ, Eberhart CG, Rodriguez FJ. INSM1 expression is frequent in primary central nervous system neoplasms but not in the adult brain parenchyma. J Neuropathol Exp Neurol. 2018 May 1;77(5):374-82.
Key words: INSM1 expression, nervous system, neoplasms, brain parenchyma
PMID: 29490065

2. Baras AS, Naidoo J, Hann CL, Illei PB, Reninger CW 3rd, Lauring J. Rediagnosis of lung cancer as NUT midline carcinoma based on clues from tumor genomic profiling. J Natl Compr Canc Netw. 2018 May;16(5):467-72.
Key words: carcinoma, tumor genomic profiling, lung cancer
PMID: 29752320

3. Bloch EM, Ness PM, Tobian AAR, Sugarman J. Revisiting blood safety practices given emerging data about Zika Virus. N Engl J Med. 2018 May 10;378(19):1837-41.
Key words: blood safety practices, Zika virus
PMID: 29742377

4. Bloch EM, Yang Y, He M, Tonnetti L, Liu Y, Wang J, Guo Y, Li H, Leiby DA, Shan H. A pilot serosurvey of Babesia microti in Chinese blood donors. Vox Sanguinis. 2018 May;113:345-9.
Key words: Babesia ; China; blood donors; blood transfusion; epidemiology
PMID: 29582438

5. Ciháková D, Eaton WW, Talor MV, Harkus UH, Demyanovich HK, Rodriguez K, Feldman S, Kelly DL. Gliadin-related antibodies in schizophrenia (letter to editor). Schizophr Res. 2018 May;195:585-6.
Key words: schizophrenia, gliadin, antibodies, gluten
PMID: 28886891

6. Clark DJ, Hu Y, Bocik W, Chen L, Schnaubelt M, Roberts R, Shah P, Whiteley G, Zhang H. Evaluation of NCI-7 Cell Line Panel as a Reference Material for Clinical Proteomics. J Proteome Res. 2018 Jun;17(6):2205-15.
Key words: clinical proteomics, mass spectrometry, cell culturing, proteomics reference material
PMID: 29718670

7. Lee SA, Noel S, Sadasivam M, Allaf ME, Pierorazio PM, Hamad ARA, Rabb H. Characterization of kidney CD45intCD11bintF4/80+ MHCII+ CX3CR1+ Ly6C-"intermediate mononuclear phagocytic cells." PLoS One. 2018 June;13(6):e0198608.
Key words: kidney, phagocytic cells
PMID: 29856833

8. Lokhandwala PM, O'Neal A, Patel EU, Brunker PAR, Gehrie EA, Zheng G, Kickler TS, Ness PM, Tobian AAR. Hemostatic profile and safety of pooled cryoprecipitate up to 120 hours after thawing. Transfusion. 2018 May; 58(5):1126-31.
Key words: hemostatic, cryoprecipitate
PMID: 29479708

9. Martin IW, Dionne K, Deml SM, Wengenack NL, Parrish NM. Automated broth-based systems versus the MYCOTB plate for antimicrobial susceptibility testing of the Mycobacterium tuberculosis complex: challenges in interpretation. Diagn Microbiol Infect Dis. 2018 May;91(1):38-41.
Key words: drug susceptibility testing methods, mycobacterium tuberculosis complex
PMID: 29422273

10. Pallavajjala A, Kim D, Li T, Ghiaur G, Jones RJ, Burns KH, Salzberg SL, Ning Y. Genomic characterization of chromosome translocations in patients with T/myeloid mixed-phenotype acute leukemia. Leuk Lymphoma. 2018 May;59(5):1231-8.
Key words: leukemic progenitor cells, cytogenetics, molecular genetics

11. Rooper LM, Bishop JA, Westra WH. INSM1 is a sensitive and specific marker of neuroendocrine differentiation in head and neck tumors. Am J Surg Pathol. 2018 May;42(5):665-71.
Key words: head and neck tumors, INSM1


12. Sun S, Hu Y, Jia L, Toghi Eshghi S, Liu Y, Shah P, Zhang H. Site-specific profiling of serum glycoproteins Using N-linked glycan and glycosite analysis reveals atypical N-glycosylation sites on albumin and alpha-1B-glycoprotein. Anal Chem. 2018 May 15;90(10):6292-9.
Key words: serum glycoproteins, glycan, glycosite, N-glycosylation, albumin

13. Walker A, Singh A, Tully E, Woo J, Le A, Nguyen T, Biswal S, Sharma D, Gabrielson E. Nrf2 signaling and autophagy are complementary in protecting breast cancer cells during glucose deprivation. Free Radic Biol Med. 2018 May 20;120:407-13.
Key words: ATG7, antioxidant response, autophagy, beclin-1, Nrf2

14. Wang TY, Lee D, Fox-Talbot K, Arking DE, Chakravarti A, Halushka MK. Cardiomyocytes have mosaic patterns of protein expression. Cardiovasc Pathol. 2018 May-June;34:50-7.
Key words: myosin light chain, proteomics, myomesin, cardiomyocyte, expression
PMID: 29677652

15. Yao JD, Young S, Heilek GM, Marino E, Paxinos EE, Marins EG, Valsamakis A. Diagnosis and monitoring of HCV infection using the cobas® HCV test for use on the cobas® 6800/8800 systems. J Clin Virol. 2018 May;102:63-69.
Key words: chronic hepatitis C, HCV RNA quantification, hepatitis C virus, cobas(®) 6800/8800, cobas(®) HCV test
PMID: 29518694

1. Amukele TK, Jones R, Elbireer A. Test cost and test accuracy in clinical laboratories in Kampala, Uganda. Am J Clin Pathol 2018 Apr;00:1-7.
Key words: quality, accuracy, cost, laboratory, Africa

PMID: 29659678

2. Bakshi RP, Breakey J, Manohar M, Jois B, Fuchs EJ, Marzinke MA. Short Communication: Specimen processing impacts tissue tenofovir pharmacokinetic measurements. AIDS Res Hum Retroviruses. 2018 Apr;34(4):354-6.
Key words: PK/PD, antiretroviral, biopsy, tenofovir, tissue
PMID: 29258331

3. Birkbak NJ, Li Y, Pathania S, Greene-Colozzi , Dreze M, Bowman-Colin C2, Sztupinszki Z1, Krzystanek M, Diossy M, Tung N, Ryan PD, Garber JE, Silver DP, Iglehart JD, Wang ZC, Szuts D, Szallasi Z, Richardson AL. Overexpression of BLM promotes DNA damage and increased sensitivity to platinum salts in triple negative breast and serous ovarian cancers. Ann Oncol. 2018 Apr 1;29(4):903-9.
Key words: platinum-based chemotherapy, gene expression-based predictor of treatment sensitivity, triple-negative breast cancer, ovarian cancer

4. Clemmensen T, Matoso A, Graham T, Lai WS, Rais-Bahrami S, Gordetsky J. Pathologic and clinical characteristics of early onset renal cell carcinoma. Hum Pathol 2018 Apr;74:25-31.
Key words: cancer grading, cancer staging, early onset, radical nephrectomy
PMID: 29133143

5. Diny NL, Baldeviano GC, Talor MV, Barin JG, Ong S, Bedja D, Hays AG, Gilotra NA, Coppens I, Rose NR, ?iháková D. Eosinophil-derived IL-4 drives inflammatory dilated cardiomyopathy. J Exp Med. 2017 Apr 3;214(4):943-57.
Key words: eosinophil, IL-4, cardiomyopathy
PMID: 28302646

6. Fite JJ, Rosenthal DL, VandenBussche CJ. When words matter: A "suspicious" urinary tract cytology diagnosis improves patient follow?up among nonurologists. Cancer Cytopathol. 2018 Apr;126(4):282-8.
Key words: cytology, bladder cancer, urothelial carcinoma, urine
PMID: 29360190

7. Höti N, Yang S, Hu Y, Shah P, Haffner MC, Zhang H. Overexpression of ? (1,6) fucosyltransferase in the development of castration-resistant prostate cancer cells. Prostate Cancer Prostatic Dis. 2018 Apr;21(1):137-46.
Key words: GNAS, gastricheterotopia
PMID: 29339807

8. Hummert P, Parsons TL, Ensign LM, Hoang T, Marzinke MA. Validation and implementation of liquid chromatographic-mass spectrometric (LC-MS) methods for the quantification of tenofovir prodrugs. J Pharm Biomed Anal. 2018 Apr;152:248-56.
Key words: antiretroviral, HIV, LC-MS/MS, Prodrug, Tenofovir, validation
PMID: 29433097

9. Hutchings D, Maleki Z, Rodriguez EF. Pulmonary non-small cell carcinoma with morphologic features of adenocarcinoma or "non-small cell carcinoma favor adenocarcinoma" in cytologic specimens share similar clinical and molecular genetic characteristics. Am J Clin Pathol. 2018 Apr;149(6):514-21.
Key words: non-small cell lung carcinoma, clinical staging, molecular
PMID: 29635384

10. Mao CP, Peng S, Yang A, He L, Tsai YC, Hung CF, Wu TC. Programmed self-assembly of peptide-major histocompatibility complex for antigen-specific immune modulation. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4032-E4040.
Key words: T cell signaling, annexin V, antigen-specific lymphocyte, immune modulation, protein self-assembly
PMID: 29632186

11. Pancholi P, Carroll KC, Buchan BW, Chan RC, Dhirman N, Ford B, Granato PA, Harrington AT, Hernandez DR, Humphries RM, Jindra MR, Ledoboer NA, Miller SA, Mochon AB, Morgan MA, Patel R, Schreckenberger PC, Stamper PD, Simner PJ, Tucci NE, Zimmerman C, Wolk DM. Multicenter evaluation of the accelerate PhenoTest BC Kit for rapid identification and phenotypic antimicrobial susceptibility testing using morphokinetic cellular analysis. J Clin Microbiol. 2018 Apr;26;56(4):e01329-17.
Key words: FISH, MIC, antimicrobial susceptibility testing, bacteremia, blood culture, candidemia
PMID: 29305546

12. Salimian KJ, Fazeli R, Zheng G, Ettinger D, Maleki Z. V600E BRAF versus Non-V600E BRAF mutated lung adenocarcinomas: cytomorphology, histology, coexistence of other driver mutations and patient characteristics. Acta Cytol. 2018 Mar-Apr;62(2):79-84.
Key words: BRAF, lung adenocarcinoma, cytology, next-generation sequencing, fine-needle aspiration
PMID: 29320776

13. Tamma PD, Fan Y, Bergman Y, Sick-Samuels AC, Hsu AJ, Timp W, Simner PJ, Prokesch BC, Greenberg DE. Successful treatment of persistent Burkholderia cepacia complex bacteremia with ceftazidime-avibactam.
Antimicrob Agents Chemother. 2018 Apr;62(4):e02213-17.
Key words: burkholderia cepacia complex, whole-genome sequencing, bacteremia, ceftazidime-avibactam

14. Ziogas NK, Koliatsos VE. Primary traumatic axonopathy in mice subjected to impact acceleration: a reappraisal of pathology and mechanisms with high-resolution anatomical methods. J Neurosci 2018 Apr;38(16):4031-47.
Key words: asonopathy, NMNAT2-SARM1, CLARITY, corticospinal tract, traumatic brain injury
PMID: 29567804

1. Chen S, Patil PA, Lepe M, Lombardo KA, Amin A, Matoso A. Retrospective analysis of atypical glands suspicious for carcinoma in transurethral resection of prostate. Appl Immunohistochem Mol Morphol. 2018 Mar;26(3):186-91.
Key words: atypical glands, carcinoma, transurethral resection, prostate
PMID: 27299192

2. Detrick B, Gangaputra S, Palsgrove DN, Heaney CD, Hooks JJ, Nida Sen H. Elevated serum levels of IL-6 and CXCL9 in autoimmune retinopathy (AIR) patients. J Neuroimmunol. 2018 Mar 15;316:74-79.
Key words: Autoimmune retinopathy, retina, cytokines, ocular inflammation, IL-6
PMID: 29310941

3. Halushka MK, Fromm B, Peterson KJ, McCall MN. Big strides in cellular microRNA expression. Trends Genet. 2018 Mar;34(3):165-7.
Key words: RNA-seq, cell expression, microRNA
PMID: 29361313

4. Kosmides AK, Necochea K, Hickey JW, Schneck JP. Separating T Cell targeting components onto magnetically clustered nanoparticles boosts activation. Nano Lett. 2018 Mar 14;18(3):1916-24.
Key words: artificial antigen presenting cell, CD8+ T cell, immunotherapy, magnetic clustering, nanoparticle
PMID: 29488768

5. Li Y, Reuter VE, Matoso A, Netto GJ, Epstein JI, Argani P. Re-evaluation of 33 'unclassified' eosinophilic renal cell carcinomas in young patients. Histopathology. 2018 Mar;72(4):588-600.
Key words: eosinophilic solid and cystic RCC, fumarate hydratase, paediatric; renal cell carcinoma, succinate dehydratase

6. Lilo MT, Bishop JA, Olson MT, Ali SZ. Adamantinoma-like Ewing sarcoma of the parotid gland: Cytopathologic findings and differential diagnosis. Diagn Cytopathol. 2018 Mar;46(3):263-6.
Key words: Ewing sarcoma, parotid gland, adamantinoma, cytopathology
PMID: 29034595

7. McCuiston A, Bishop JA. Usefulness of NKX2.2 Immunohistochemistry for distinguishing Ewing sarcoma from other sinonasal small round blue cell tumors. Head Neck Pathol. 2018 Mar;12(1):89-94.
Key words: CD99, EWSR1-FLI1, Ewing sarcoma, NKX2.2, primitive neuroectodermal tumor
No PMID available

8. Meyers CA, Xu J, Zhang L, Asatrian G, Ding C, Yan N, Broderick K, Sacks J, Goyal R, Zhang X, Ting K, Péault B, Soo C, James AW. Early immunomodulatory effects of implanted human perivascular stromal cells during bone formation. Tissue Eng Part A. 2018 Mar;24(5-6):448-57.
Key words: Mesenchymal stem cell, bone tissue engineering, perivascular stem cell, pericyte, adipose derived stromal cell

PMID: 28683667

1. Blakely AM, Matoso A, Patil PA, Taliano R, Machan JT, Miner TJ, Lombardo KA, Resnick MB, Wang LJ. Role of immune microenvironment in gastrointestinal stromal tumors. Histopathology. 2018 Feb;72(3):405-13.
Key words: microenvironment, stromal tumor
PMID: 28871595

2. Canto MI, Montgomery E. Wide-area transepithelial sampling with 3-dimensional cytology: Does it detect more dysplasia or yield more hype? Gastrointest Endosc. 2018 Feb;87(2):356-39.
Key words: dysplasia, transepithelial sampling, 3-dimensional cytology
PMID: 29406925

3. Eshleman SH, Piwowar-Manning E, Sivay MV, Debevec B, Veater S, McKinstry L, Bekker LG, Mannheimer S, Grant RM, Chesney MA, Coates TJ, Koblin BA, Fogel JM. Performance of the BioPlex 2200 HIV Ag-Ab assay for identifying acute HIV infection. J Clin Virol. 2018 Feb - Mar;99-100:67-70.
Key words: HIV, acute, Ag/Ab assay, BioPlex
PMID: 29346085

4. Goel R, Chappidi MR, Patel EU, Ness PM, Cushing MM, Frank SM, Tobian AAR. Trends in red blood cell, plasma, and platelet transfusions in the United States, 1993-2014. JAMA. 2018 Feb 27;319(8):825-7.
Key words: blood transfusion, plasma, platelets
PMID: 29486023

5. Grabowski MK, Herbeck JT, Poon AFY. Genetic cluster analysis for HIV prevention. Curr HIV/AIDS Rep. Feb 2018; https://doi.org/10.1007/s11904-018-0384-1 (Open Access):1-8.
Key words: Prevention, HIV, cluster identification, genetic similarity clusters, HIV epidemiology
PMID: 29460226

6. Lai S, Heaphy CM, Rizzo AJ, Celentano DD, Gerstenblith G, Li J, Moore RD, Treisman G, Chen S, Foster P, Kickler T, Lai H. Cocaine use may induce telomere shortening in individuals with HIV infection. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Feb 2;84(Pt A):11-17.
Key words: Cocaine use, HIV infection, HIV-associated comorbidities, premature aging, telomere length, telomere shortening
PMID: 29410247

7. Laeyendecker O, Konikoff J, Morrison DE, Brookmeyer R, Wang J, Celum C, Morrison CS, Abdool Karim Q, Pettifor AE, Eshleman SH. Identification and validation of a multi-assay algorithm for cross-sectional HIV incidence estimation in populations with subtype C infection. J Int AIDS Soc. 2018 Feb;21(2).
Key words: HIV, subtype C infection, multi-assay algorithm
PMID: 29489059

8. Maleki Z, Miller JA, Arab SE, Fadda G, Bo P, Wise O, Rossi ED, Jhala N, Ashish C, Ali SZ, Wang H. "Suspicious" salivary gland FNA: Risk of malignancy and interinstitutional variability. Cancer Cytopathol. 2018 Feb;126(2):94-100.
Key words: cytology, fine-needle aspiration (FNA), interinstitutional variability, risk of malignancy

9. Mariani LH, Martini S, Barisoni L, Canetta PA, Troost JP, Hodgin JB, Palmer M, Rosenberg AZ, Lemley KV, Chien HP, Zee J, Smith A, Appel GB, Trachtman H, Hewitt SM, Kretzler M, Bagnasco SM. Interstitial fibrosis scored on whole-slide digital imaging of kidney biopsies is a predictor of outcome in proteinuric glomerulopathies. Nephrol Dial Transplant. 2018 Feb 1;33(2):310-8.
Key words: gene expression, interstitial fibrosis, kidney biopsy, proteinuria
PMID: 28339906

10. Paluru S, Ulbright TM, Amin M, Montironi R, Epstein JI. The morphologic spectrum of sertoliform cystadenoma of the rete testis: a series of 15 cases. Am J Surg Pathol. 2018 Feb;42(2):141-9.
Key words: sertoliform cystadenoma, rete testis, genitourinary pathology
PMID: 29240582

11. Salimian KJ, Waters KM, Eze O, Pezhouh MK, Tarabishy Y, Shin EJ, Canto MI, Voltaggio L, Montgomery EA. Definition of Barrett Esophagus in the United States: support for retention of a requirement for goblet cells. Am J Surg Pathol. 2018 Feb;42(2):264-8.
Key words: Barrett esophagus, esophageal adenocarcinoma, intestinal metaplasia, columnar-lined mucosa, goblet cells
PMID: 29016405

12. Sidhom JW, Bessell CA, Havel JJ, Kosmides A, Chan TA, Schneck JP. ImmunoMap: A bioinformatics tool for T-cell repertoire analysis. Cancer Immunol Res. 2018 Feb;2:151-62.
Key words: ImmunoMap, TCR signatures, sequence analysis
PMID: 29263161

13. Xing D, Banet N, Sharma R, Vang R, Ronnett BM, Illei PB. Aberrant Pax-8 expression in well-differentiated papillary mesothelioma and malignant mesothelioma of the peritoneum: a clinicopathologic study. Hum Pathol. 2018 Feb;72:160-6.
Key words: immunohistochemistry, malignant mesothelioma, pax-8, peritoneum, well-differentiated papillary mesothelioma
PMID: 29241740

14. Zhou AG, Levinson KL, Rosenthal DL, VandenBussche CJ. Performance of ovarian cyst fluid fine-needle aspiration cytology. Cancer Cytopathol. 2018 Feb;126(2):112-21.
Key words: ovary, fine needle aspiration, cytology, ovarian cyst
PMID: 28834408

1. Baena-Del Valle JA, Zheng Q, Esopi DM, Rubenstein M, Hubbard GK, Moncaliano MC, Hruszkewycz A, Vaghasia A, Yegnasubramanian S, Wheelan SJ, Meeker AK, Heaphy CM, Graham MK, De Marzo AM. MYC drives overexpression of telomerase RNA (hTR/TERC) in prostate cancer. J Pathol. 2018 Jan;244(1):11-24.
Key words: MYC, RNA in situ hybridization, TERC telomerase RNA component, prostate carcinoma, telomerase
PMID: 28888037

2. Chen W, Wang S, Mestre AA, Fu C, Makarem A, Xian F, Hayes LR, Lopez-Gonzalez R, Drenner K, Jiang J, Cleveland DW, Sun S. C9ORF72 GGGGCC repeat-associated non-AUG translation is upregulated by stress through eIF2? phosphorylation. Nat Communications. 2018 Jan;9;Article number 51 - Open Access
Key words: hexanucleotide, amyotrophic lateral sclerosis,
PMID: 29302060

3. Dezern AE, Borowitz MJ. ICCS/ESCCA consensus guidelines to detect GPI-deficient cells in paroxysmal nocturnal hemoglobinuria (PNH) and related disorders part 1 - clinical utility. Cytometry B Clin Cytom. 2018 Jan;94(1):16-22.
Key words: complement inhibitors; aplastic anemia; paroxysmal nocturnal hemoglobinuria
PMID: 29236352

4. Epstein JI. Prostate cancer grading: A decade after the 2005 modified system. Mod Pathol. 2018 Jan;31:S47-63
Key words: Prostate adenocarcinoma, Gleason grading, prostate cancer
PMID: 29297487

5. Grabowski MK, Reynolds SJ, Kagaayi J, Gray RH, Clarke W, Nakigozi G, Laeyndecker O, Redd AD, Billioux V, Ssekubugu R, Nalugoda F, Wawer MJ, Serwadda D, Quinn TC, Tobian AAR. The validity of self-reported antiretroviral use in persons living with HIV: a population-based study. AIDS. 2018 Jan;32(3):363-9.
Key words: antiretroviral, HIV, self-reporting
PMID: 29194115

6. Hata T, Dal Molin M, McGregor-Das A, Song TJ, Wolfgang C, Eshleman JR, Hruban RH, Goggins M. Simple detection of telomere fusions in pancreatic cancer, intraductal papillary mucinous neoplasm, and pancreatic cyst fluid. J Mol Diagn. 2018 Jan;20(1):46-55.
Key words: telomere, pancreatic cancer, neoplasm, pancreatic cyst fluid
PMID: 29229290

7. Hooper JE, Richardson H, Maters AW, Carroll KC, Pronovost PJ. The Association of Departmental Quality Infrastructure and Positive Change: A Pathology Department Illustration. Acad Pathol. 2018 Jan 18;5: 2374289517744753. eCollection
Key words: quality improvement, infrastructure, pathology, laboratory; patient safety; quality assurance https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777549/
PMID: 29376115

8. Hui Y, Lombardo KA, Quddus MR, Matoso A. Cell polarity reversal distinguishes true micropapillary growth from retraction artifact in invasive urothelial carcinoma. Appl Immunohistochem Mol Morphol. 2018 Jan;26(1):e1-e6.
Key words: urothelial carcinoma, micropapillary, EMA, E-cadherin
PMID: 28800010

9. Nguyen D, Haley L, Pallavajjala A, Gojo I, Ning Y. Identification of a novel KMT2A-SEPT14 fusion in acute myeloid leukemia. Leuk Lymphoma. 2018 Jan;59(1):265-7. (Letter to Editor)
Key words: leukemia, gene fusion
PMID: 28573893

10. Patel HD, Tosoian JJ, Carter HC, Epstein JI. Adverse pathologic findings at radical prostatectomy: Is there a favorable intermediate-risk group? JAMA Oncology. 2018 Jan 4:89-92.
Key words: active surveillance, prostate adenocarcinoma, Gleason grading
No PMID available

11. Sfanos KS, Yegnasubramanian S, Nelson WG, DeMarzo AM. The inflammatory microenvironment and microbiome in prostate cancer development. Nat Rev Urol. 2018 Jan;15(1):11-24.
Key words: chronic inflammation, prostate cancer, prostatic diseases, urinary tract infection
PMID: 29089606

12. Shen J, Chen X, Jia H, Meyers CA, Shrestha S, Asatrian G, Ding C, Tsuei R, Zhang X, Peault B, Ting K, Soo C, James AW. Effects of WNT3A and WNT16 on the osteogenic and adipogenic differentiation of perivascular stem/stromal cells. Tissue Eng Part A. 2018 Jan;24(1-2):68-80.
Key words: Mesenchymal stem cell, perivascular stem cell, bone tissue engineering, adipose tissue engineering, Wnt signaling
PMID: 28463594

13. Shrestha E, White JR, Yu SH, Kulac I, Ertunc O, De Marzo AM, Yegnasubramanian S, Mangold LA, Partin AW, Sfanos KS. Profiling the urinary microbiome in men with positive versus negative biopsies for prostate cancer. J Urol. 2018 Jan;199(1):161-71.
Key words: bacteria, inflammation, microbiota, prostatic neoplasms, urinary tract
PMID: 28797714

14. Tosoian JJ, Alam R, Ball MW, Carter HB, Epstein JI. Managing high-grade prostatic intraepithelial neoplasia (HGPIN) and atypical glands on prostate biopsy. Nat Rev Urol. 2018 Jan;15(1):55-66.
Key words: prostate needle biopsy, high grade prostatic intraepithelial neoplasia, prostate adenocarcinoma

PMID: 28858331

15. Ware AD, Jacquot C, Tobian AAR, Gehrie EA, Ness PM, Bloch EM. Pathogen reduction and blood transfusion safety in Africa: strengths, limitations and challenges of implementation in low-resource settings. Vox Sang. 2018 Jan;113(1):3-12.
Key words: Africa; blood transfusion, pathogen reduction, transfusion-transmitted infections
PMID: 29193128

1. Argani P, Kao YC, Zhang L, Bacchi C, Matoso A, Alaggio R, Epstein JI, Antonescu CR. Primary renal sarcomas with BCOR-CCNB3 gene fusion: A report of 2 cases showing histologic overlap with clear cell sarcoma of kidney, suggesting further link between BCOR-related sarcomas of the kidney and soft tissues. Am J Surg Pathol. 2017 Dec;41(12):1702-12.
Key words: Kidney, BCOR, clear cell sarcoma
PMID: 28817404

2. Assarzadegan N, Montgomery E. Gastric polyps. Diagnostic Histopathology 2017 Dec;23(12):521-9.
Key words: gastric polyps, pathology, review

3. Corsello A, Di Dalmazi G, Pani F, Chalan P, Salvatori R, Caturegli P. Walter E. Dandy: his contributions to pituitary surgery in the context of the overall Johns Hopkins Hospital experience. Pituitary. 2017 Dec;20(6):683-91.
Key words: Harvey W. Cushing, history of endocrinology, pituitary surgery, Walter E. Dandy
PMID: 28871375

4. Eze O, Jones R, Montgomery E. A practical approach for diagnosis of appendiceal mucinous neoplasms. Diagnostic Histopathology 2017 Dec;23(12):530-5.
Key words: appendiceal mucinous adenoma, appendiceal mucinous neoplasm, HAMN, high grade appendiceal mucinous neoplasm, LAMN

5. Greer AE, Ou SS, Wilson E, Piwowar-Manning E, Forman MS, McCauley M, Gamble T, Ruangyuttikarn C, Hosseinipour MC, Kumarasamy N, Nyirenda M, Grinsztejn B, Pilotto JH, Kosashunhanan N, Gonçalves de Melo M, Makhema J, Akelo V, Panchia R, Badal-Faesen S, Chen YQ, Cohen MS, Eshleman SH, Thio CL, Valsamakis A. A comparison of hepatitis B virus infection in HIV-infected and HIV-uninfected participants enrolled in a multi-national clinical trial: HPTN 052. J Acquir Immune Defic Syndr 2017 Dec;76(4):388-93.
Key words: HIV, hepatitis B
PMID: 28749822

6. Keyashian K, Duregon E, Brinkerhoff B, Bradley L, Larson B, Lim J, Modiano N, Collins J, Morgan TK, Hooper JE. Uses and limitations of IgG4 positive plasma cells in evaluating ulcerative colitis. J Gastrointestin Liver Dis Dec 2017;26(4):428-9.
Key words: IgG4, ulcerative colitis, plasma cells
PMID: 29253063

7. Savage J, Adams E, Veras E, Murphy KM, Ronnett BM. Choriocarcinoma in women: analysis of a case series with genotyping. Am J Surg Pathol. 2017 Dec;41(12):1593-606.
Key words: choriocarcinoma, genotyping
PMID: 28877059

8. Voltaggio L, Montgomery EA. Diagnosis and management of Barrett-Related neoplasia in the modern era. Surg Path Clins 2017 Dec;10(4):781-800.
Key words: Barrett dysplasia; Barrett neoplasia; Endoscopic mucosal resection; Endoscopic submucosal dissection; Radiofrequency ablation
PMID: 29103533

1. Baena-Del Valle JA, Zheng Q, Hicks JL, Fedor H, Trock BJ, Morrissey C, Corey E, Cornish TC, Sfanos KS, De Marzo AM. Rapid Loss of RNA Detection by In Situ Hybridization in Stored Tissue Blocks and Preservation by Cold Storage of Unstained Slides. Am J Clin Pathol. 2017 Nov 2;148(5):398-415.
Key words: RNA in situ hybridization, branched DNA amplification, formalin-fixed, paraffin-embedded tissues
PMID: 29106457

2. Borhan WM, Cimino-Mathews AM, Montgomery EA, Epstein JI. Immunohistochemical differentiation of plasmacytoid urothelial carcinoma from secondary carcinoma involvement of the bladder. Am J Surg Pathol. 2017 Nov;41(11):1570-5.
Key words: plasmacytoid, urothelial carcinoma, breast carcinoma, signet ring cell carcinoma
PMID: 28786878

3. Gehrie EA, Tobian AAR. Finally, what we have been waiting for: evidence that transfusion of RBCs at the extreme of the storage spectrum is safe. Lancet Haematol. 2017 Nov;4(11):e504-e505.
Key words: red blood cells, transfusion, storage
PMID: 29021124

4. Hickey JW, Vicente FP, Howard GP, Mao HQ, Schneck JP. Biologically inspired design of nanoparticle artificial antigen-presenting cells for immunomodulation. Nano Lett. 2017 Nov 8;17(11):7045-54.
Key words: Artificial antigen presenting cell; CD8+ T cell; immunotherapy; nanoparticle; particle size; receptor clustering
PMID: 28994285

5. Kamalden TA, Macgregor-Das AM, Kannan SM, Dunkerly-Eyring B, Khaliddin N, Xu Z, Fusco AP, Yazib SA, Chow RC, Duh EJ, Halushka MK, Steenbergen C, Das S. Exo-miR-15a transfer from the pancreas augments diabetic complications by inducing oxidative stress. Antioxid Redox Signal. 2017 Nov 1;27(13):913-30.
Key words: microRNA, diabetic vasculopathy, exosomes, oxidative stress, pancreatic ?- cells
PMID: 28994285

6. Rooper LM, Sharma R, Li QK, Illei PB, Westra WH. INSM1 demonstrates superior performance to the individual and combined use of synaptophysin, chromogranin and CD56 for diagnosing neuroendocrine tumors of the thoracic cavity. Am J Surg Pathol. 2017 Nov;41(11):1561-9.
Key words: immunohistochemical analysis, thoracic biopsies,synaptophysin, chromogranin, CD56
PMID: 28719469

7. Sadimin E, Chen Y, Wang L, Argani P, Epstein JI. Chromosomal abnormalities of high grade mucinous tubular and spindle cell carcinoma of the kidney. Histopathology. 2017 Nov; 71: 719-24.
Key words: renal cell carcinoma, mucinous and tubular renal cell carcinoma, chromosome aberration
PMID: 28656700

8. Singhi AD, Arnold CA, Lam-Himlin DM, Nikiforova MN, Voltaggio L, Canto MI, McGrath KM, Montgomery EA. Targeted next-generation sequencing supports epidermoid metaplasia of the esophagus as a precursor to esophageal squamous neoplasia. Mod Pathol. 2017 Nov;30(11):1613-21.
Key words: sequencing, epidermoid metaplasia, esophagus, esophageal squamous neoplasia
PMID: 28731047

9. Thompson ED, Taube JM, Asch-Kendrick RJ, Ogurtsova A, Xu H, Sharma R, Meeker A, Argani P, Emens LA, Cimino-Mathews A. PD-L1 expression and the immune microenvironment in primary invasive lobular carcinomas of the breast. Mod Pathol. 2017 Nov;30(11):1551-60.
Key words: PD-L1, lobular carcinoma, breast cancer, tumor immune microenvironment
PMID: 28731046

10. Yang W, Shah P, Hu Y, Toghi Eshghi S, Sun S, Liu Y, Zhang H. Comparison of enrichment methods for intact N- and O-linked glycopeptides using strong anion exchange and hydrophilic interaction liquid chromatography. Anal Chem. 2017 Nov 7;89(21):11193-7.
Key words: glycoproteomics, N-linked, O-linked, HILIC, SAX
PMID: 29016103

1. Ayars M, O'Sullivan E, Macgregor-Das A, Shindo K, Kim H, Borges M, Yu J, Hruban RH, Goggins M. IL2RG, identified as overexpressed by RNA-seq profiling of pancreatic intraepithelial neoplasia, mediates pancreatic cancer growth. Oncotarget. 2017 Oct;8(48):83370-83.
Key words: pancreatic cancer, PanIN, RNA-seq, IL2RG, JAK3

2. Baradan R, Hollander JM, Das S. Mitochondrial miRNAs in Diabetes: Just the Tip of the Iceberg. Can J Physiol Pharmacol. 2017 Oct;95(10):1156-62.
Key words: mitomiR, diabetes, metabolism, microARN mitochondrial

3. Barin JG, Talor MV, Diny NL, Ong S, Schaub JA, Gebremariam E, Bedja D, Chen G, Choi HS, Hou X, Wu L, Cardamone AB, Peterson DA, Rose NR, ?iháková D. Regulation of autoimmune myocarditis by host responses to the microbiome. Exp Mol Pathol. 2017 Oct;103(2):141-52.
Key words: microbiome, myocarditis, innate lymphoid cells, autoimmunity
PMID: 28822770

4. Farley JE, Starbird LE, Anderson J, Perrin NA, Lowensen K, Ross T, Carroll KC. Methodologic considerations of household-level methicillin-resistant Staphylococcus aureus decolonization among persons living with HIV. Am J Infect Control. 2017 Oct 1;45(10):1074-80.
Key words: clinical tria, pilot, social network, MRSA
PMID: 28684128

5. Gehrie EA, Keiser A, Haglock-Adler CJ, Strathmann F, Booth GS. Detecting pharmaceuticals in the red blood cell inventory of a hospital blood bank. J Pediatr. 2017 Oct;189:227-31.
Key words: blood, transfusion, pediatrics, drugs, contamination
PMID: 28669612

6. McCall MN, Kim MS, Adil M, Patil AH, Lu Y, Mitchell CJ, Leal-Rojas P, Xu J, Kumar M, Dawson VL, Dawson TM, Baras AS, Rosenberg AZ, Arking DE, Burns KH, Pandey A, Halushka MK. Toward the human cellular microRNAome. Genome Res, 2017 Oct;27(10):1769-81.
Key words: cellular microRNAome, gene expression
PMID: 28877962

7. Rowe SP, Gorin MA, Solnes LB, Ball MW, Choudhary A, Pierorazio PM, Epstein JI, Javadi MS, Allaf ME, Baras AS. Correlation of 99mTc-sestamibi uptake in renal masses with mitochondrial content and multi-drug resistance pump expression. EJNMMI Res. 2017 Oct 2;7(1):80.
Key words: Oncocytoma; Renal cell carcinoma; SPECT/CT; Small renal mass
PMID: 28971329

8. Shindo K, Yu J, Suenaga M, Fesharakizadeh S, Cho C, Macgregor-Das A, Siddiqui A, Witmer PD, Tamura K, Song TJ, Navarro Almario JA, Brant A, Borges M, Ford M, Barkley T, He J, Weiss MJ, Wolfgang CL, Roberts NJ, Hruban RH, Kein AP, Goggins M. Deleterious germline mutations in patients with apparently sporadic pancreatic adenocarcinoma. J Clin Oncol. 2017 Oct 20;35(30):3382-00.
Key words: pancreatic adenocarcinoma, germline mutation

PMID: 28767289

9. Siddique AS, Corney DC, Mangray S, Lombardo KA, Chen S, Marwaha AS, Resnick MB, Herzlinger M, Matoso A. Clinicopathologic and gene expression analysis of initial biopsies from patients with eosinophilic esophagitis refractory to therapy. Hum Pathol. 2017 Oct;68;79-86.
Key words: ALOX15; CCL26; Eosinophilic esophagitis; Gene expression; Proton pump inhibitor; RTNLB


10. Thomas SN, Chen L, Liu Y, Höti N, and Zhang H. Targeted proteomic analyses of Histone H4 acetylation changes associated with homologous recombination deficient high-grade serous ovarian carcinomas. J Proteome Res. 2017 Oct 6;16(10):3704-10.
Key words: Histone, homologous recombination, lysine acetylation, mass spectrometry, ovarian cancer
PMID: 28866885

11. VandenBussche CJ, Adams CL, McDonald OG, Whitworth SA, Ali SZ. The fine needle aspiration of translocation sarcomas. Cytopathology. 2017 Oct;28(5):356-63.
Key words: sarcoma, fine needle aspiration, cytology, cytopathology, translocation
PMID: 28718513

1.Allison DB, McCuiston A, VandenBussche CJ. The presence of neuroendocrine features generates a broad differential diagnosis in the fine needle aspiration of bone and soft tissue neoplasms. J Am Soc Pathol. 2017 Sept-Oct;6(5):185-93.
Key words: neuroendocrine, fine needle aspiration, bone neoplasm
No PMID available

2.Amukele TK, Hernandez J, Snozek CLH, Wyatt RG, Douglas M, Amini R, Street J. Drone transport of chemistry and hematology samples over long distances. Am J Clin Pathol. 2017 Sept; aqx090:1-9
Key words: drone, stability, temperature, long flight, chemistry, hematology
PMID: 29016811

3.Charu V, Cimino-Mathews A. Peripheral nerve sheath tumors of the breast. Semin Diagn Pathol. 2017 Sep;34(5):420-6.
Key words: breast soft tissue tumors, nerve sheath tumors
PMID: 28647116

4.Gehrie EA, Ness PM, Bloch EM, Kacker S, Tobian AAR. Medical and economic implications of strategies to prevent alloimmunization in sickle cell disease. Transfusion. 2017 Sep;57(9):2267-76.
Key words: Sickle Cell Disease, alloimmunization, economic implications, serologic matching
PMID: 28653325

5.Gniadek TJ, Forman MT, Martin I, Arav-Boger R, Valsamakis A. The effect of a genetic variant on quantitative real-time PCR in a case of disseminated adenovirus infection. Diagn Microbiol Infect Dis. 2017 Sep;89(1):40-43.
Key words: Aberrant real-time PCR, adenovirus, reduced fluorescence
PMID: 28629877

6.Hang JF, Charu V, Zhang ML, VandenBussche CJ. Digital image analysis supports a nuclear?to?cytoplasmic ratio cutoff value of 0.5 for atypical urothelial cells. Cancer. 2017 Sep;125(9):710-6.
Key words: The Paris System for reporting urinary cytology, atypical urothelial cells (AUC), digital imaging, nuclear-to-cytoplasmic (N:C) ratio
PMID: 28581671

7.Lilo MT, Allison DB, Younes BK, Cui M, Askin FB, Gabrielson E, Li QK. The critical role of EBUS-TBNA cytology in the staging of mediastinal lymph nodes in lung cancer patients: A correlation study with positron emission tomography findings. Cancer. 2017 Sep;125(9):717-25.
Key words: endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), fine-needle aspiration (FNA) cytology, lung cancer staging, mediastinal lymphadenopathy, positron emission tomography (PET) scan
PMID: 28609021

8.Nelson ER, Sharma R, Argani P, Cimino-Mathews A. Utility of Sox10 labeling in metastatic breast carcinomas. Hum Pathol. 2017 Sep;67:205-10
Key words: breast metastatic carcinoma; metastatic carcinoma of unknown origin, sox10
PMID: 28843711

9.Patel EU, Ness PM, Marshall CV, Gniadek T, Efron DT, Miller PM, Zeitouni JA, King KE, Bloch EM, Tobian AAR. Blood product utilization among trauma and non-trauma massive transfusion protocols at an urban academic medical center. Anesth Analg. 2017 Sep;125(3):967-74.
Key words: transfusion, blood utilization, massive transfusion protocols
PMID: 28719428

10.Rock C, Curless MS, Cantara M, Mehta S, Marrone KA, Carroll KC, Simner P, Maragakis LL. Resolution of carbapenemase-producing Klebsiella pneumoniae outbreak in a tertiary cancer center; the role of active surveillance. infect Control Hosp Epidemiol. 2017 Sep;38(9):1117-9.
Key words: surveillance, Klebsiella pneumoniae, infection control

PMID: 28693656

11. Simner PJ, Opene BNA, Chambers KK, Naumann ME, Carroll KC, Tamma PD. Carbapenemase detection among carbapenem-resistant glucose-nonfermenting Gram-negative bacilli. J Clin Microbiol. 2017 Sep;55(9):2858-64.
Key words: cinetobacter baumannii, Pseudomonas aeruginosa, carbapenem-resistant, carbapenem-resistant organisms, carbapenemase-producing

12. Urrea YR, Epstein JI. Sarcomatoid carcinoma associated with small cell carcinoma of the urinary bladder: A series of 28 cases. Hum Pathol. 2017 Sept;67:169-75.
Key words: bladder neoplasm, carcinosarcoma, sarcomatoid carcinoma, small cell carcinoma, urothelial carcinoma
PMID: 28827101

13. Waters KM, Rooper LM, Guajardo A, Halushka MK. Histopathologic differences partially distinguish syndromic aortic diseases. Cardiovasc Pathol. 2017 Sept-Oct;30:6-11.
Key words: Marfan syndrome, Loeys-Dietz syndrome, aortic aneurysm, nomenclature, histopathology
PMID: 28646716

14. Zhang ML, Zhou AG, Rosenthal DL, VandenBussche CJ. Urinary tract washing specimens containing atypical urothelial tissue fragments are significantly associated with urothelial neoplasia. Diagn Cytopathol. 2017 Sep;45(9):795-9.
Key words: urinary tract, urothelial carcinoma, cytology
PMID: 28597510

1. Collins J, Epstein JI. Prognostic significance of extensive necrosis in renal cell carcinoma. Hum Pathol. 2017 Aug;66:108-14.
Key words: clear cell papillary renal cell carcinoma, clear cell renal cell carcinoma, ISUP nucleolar grade, papillary renal cell carcinoma, renal cell carcinoma

2. Jiang RT, Yemelyanova A, Xing D1, Anchoori RK, Hamazaki J, Murata S, Seidman JD, Wang TL, Roden RBS. Early and consistent overexpression of ADRM1 in ovarian high-grade serous carcinoma. J Ovarian Res. 2017 Aug 7;10(1):53.
Key words: ADRM1, RPN13, STIC, proteasome inhibitor, ovarian/fallopian tube cancer

3. Raphael BJ, Hruban RH, et al for the Cancer Genome Atlas Research Network. Integrated genomic characterization of pancreatic ductal adenocarcinoma. Cancer Cell. 2017 Aug 14;32(2):185-203.e13.
Key words: KRAS, PDAC, RPPA, TCGA, genomic, heterogeneity

4. Yang A, Peng S, Farmer E, Zeng Q, Cheng MA, Pang X, Wu TC, Hung CF. Enhancing antitumor immunogenicity of HPV16-E7 DNA vaccine by fusing DNA encoding E7-antigenic peptide ot DNA encoding capsid protein L1 of Bovine papillomavirus. Cell & Bioscience 2017;7:46. Open Access online 2017 Aug 23.
Key words: Human papillomavirus 16, E7 antigen, L1 capsid protein, DNA vaccine, Immunotherapy https://cellandbioscience.biomedcentral.com/articles/10.1186/s13578-017-0171-5

5. Yang S, Chen L, Chan DW, Li QK, Zhang H. Protein signatures of molecular pathways in non-small cell lung carcinoma (NSCLC): comparison of glycoproteomics and global proteomics. Clin Proteomics. 2017 Aug 15;14:31.
Key words: adenocarcinoma (ADC), glycoproteins, mass spectrometry (MS), non-small cell lung carcinoma (NSCLC), proteins

6. Zhang ML, Rosenthal DL, VandenBussche CJ. Upper urinary tract washings outperform voided urine specimens to detect upper tract high?grade urothelial carcinoma. Diagn Cytopathol. 2017 Aug;45(8):700-4.
Key words: bladder cancer, urine, urothelial carcinoma, urothelial neoplasia

1. AlWadani S, Suarez MJ, Kass JJ, MacQuaid E, Edward DP, Alkatan H, Eberhart C. Subepidermal Calcified nodules of the eyelid differ in children and adults. Ophthal Plast Reconstr Surg. 2017 Jul/Aug;33(4):304-6.
Key words: calcified nodule, eyelid
PMID: 27479867

2. Belchis DA, Tseng L-H , Gniadek TA, Haley L, Lokhandwala P, Illei P, Gocke CD, Forde P, Brahmer J, Askin FA, Eshleman JA, Lin M-T. Heterogeneity of resistance mutations detectable by next-generation sequencing in TKI-treated lung adenocarcinoma. Oncotarget. 2016 Jul 19;7(29):45237-48.
Key words: EGFR, PIK3CA, tyrosine kinase resistance, next-generation sequencing, lung cancer

PMID: 27304188

3. Burns KH. Transposable elements in cancer. Nat Rev Cancer. 2017 July;17:415-24.
Key words: cancer genetics, long interspersed element-1 (LINE-1, L1), transposable element
PMID: 28642606

4. Chen I, Zhang Y, Cummings V, Cloherty GA, Connor M, Beauchamp G, Griffith S, Rose S, Gallant J, Scott HM, Shoptaw S, Del Rio C, Kuo I, Mannheimer S, Tieu HV, Hurt CB, Fields SD, Wheeler DP, Mayer KH, Koblin BA, Eshleman SH. Analysis of HIV integrase resistance in black men who have sex with men in the United States. AIDS Res Hum Retroviruses. 2017 Jul;33(7):745-8.
Key words: HIV, integrase, resistance, MSM, United States
PMID: 28384058

5. Gordetsky J, Rais-Bahrami S, Epstein JI. Pathological findings in MRI/US fusion-guided biopsy in relation to prostate cancer focal therapy. Urology. 2017 July;105:18-23. (review)
Key words: prostate biopsy; focal therapy, prostate cancer
PMID: 28238758

6. Haffner MC, Esopi DM, Chaux A, Gürel M, Ghosh S, Vaghasia AM, Tsai H, Kim K, Castagna N, Lam H, Hicks J, Wyhs N, Biswal Shinohara D, Hurley PJ, Simons BW, Schaeffer EM, Lotan TL, Isaacs WB1,5, Netto GJ, De Marzo AM, Nelson WG, An SS, Yegnasubramanian S. AIM1 is an actin-binding protein that suppresses cell migration and micrometastatic dissemination. Nat Commun 2017 Jul 26;8(1):142.
Key words: cell migration, prostate cancer, AIM1
PMID: 28747635

7. Kaufman MR, Dam KH, Van Lith LM, Hatzold K, Mavhu W, Kahabuka C, Mahlasela L, Marcell AV, Patel EU, Figueroa ME, Njeuhmeli E, Seifert-Ahanda K, Ncube G, Lija G, Bonnecwe C, Tobian AAR. Voluntary medical male circumcision among adolescents: a missed opportunity for HIV behavioral interventions. AIDS. 2017 Jul 1;31 Suppl 3:S233-S241.
Key words: adolescents, HIV prevention, HIV testing and counseling, sub-Saharan Africa, voluntary medical male circumcision
PMID: 28665881

8. Ma Y, Yang A, Peng S, Qiu J, Farmer E, Hung CF, Wu TC. Characterization of HPV18 E6-specific T cell responses and establishment of HPV18 E6-expressing tumor model. Vaccine. 2017 Jul 5;35(31):3850-8.
Key words: Human papillomavirus 18, E6 oncoprotein, DNA vaccine, Immunotherapy, HPV18-E6 tumor model
PMID: 28599791

9. Pea A, Yu J, Rezaee N, Luchini C, He J, Dal Molin M, Griffin JF, Fedor H, Fesharakizadeh S, Salvia R, Weiss MJ, Bassi C, Cameron JL, Zheng L, Scarpa A, Hruban RH, Lennon AM, Goggins M, Wolfgang CL, Wood LD. Targeted DNA sequencing reveals patterns of local progression in the pancreatic remnant following resection of intraductal papillary mucinous neoplasm (IPMN) of the pancreas. Ann Surg. 2017 Jul;266(1):133-41.
Key words: DNA sequencing, pancreas, intraductal papillary mucinous neoplasm
PMID: 27433916

10. Sivay MV, Li M, Piwowar-Manning E, Zhang Y, Hudelson SE, Marzinke MA, Amico RK, Redd A, Hendrix CW, Anderson PL, Bokoch K, Bekker LG, van Griensven F, Mannheimer S, Hughes JP, Grant R, Eshleman SH; HPTN 067/ADAPT Study Team. Characterization of HIV seroconverters in a TDF/FTC PrEP study: HPTN 067/ADAPT. J Acquir Immune Defic Syndr 2017 Jul 1;75(3):271-9.
Key words: HIV, seroconverter, PrEP, resistance, clinical trial
PMID: 28328548

11. Sun Y, Peng S, Yang A, Farmer E, TC Wu, Hung CF. Coinjection of IL2 DNA enhances E7-specific antitumor immunity elicited by intravaginal therapeutic HPV DNA vaccination with electroporation. Gene Ther. 2017 Jul;24(7):408-15.
Key words: IL-2, DNA, antitumor immunity, HPV
PMID: 28492521

12. VandenBussche CJ, Allison DB, Graham MK, Charu V, Lennon AM, Wolfgang CL, Hruban RH, Heaphy CM. Alternative lengthening of telomeres and ATRX/DAXX loss can be reliably detected in FNAs of pancreatic neuroendocrine tumors. Cancer. 2017 Jul;125(7):544-51.
Key words: Alternative lengthening of telomeres, ATRX, DAXX, pancreatic neuroendocrine tumors, fine needle aspirates
PMID: 28371511

13. Yarchoan M, Myzak MC, Johnson BA 3rd, De Jesus-Acosta A, Le DT, Jaffee EM, Azad NS, Donehower RC, Zheng L, Oberstein PE, Fine RL, Laheru DA, Goggins M. Olaparib in combination with irinotecan, cisplatin, and mitomycin c in patients with advanced pancreatic cancer. Oncotarget. 2017 Jul 4;8(27):44073-81.
Key words: BRCA2; cisplatin; irinotecan; olaparib; pancreatic cancer

PMID: 28454122

14. Zhang Y, Clarke W, Marzinke MA, Piwowar-Manning E, Beauchamp G, Breaud A, Hendrix CW, Cloherty GA, Emel L, Rose S, Hightow-Weidman L, Siegel M, Shoptaw S, Fields SD, Wheeler D, Eshleman SH. Evaluation of a multidrug assay for monitoring adherence to a regimen for HIV preexposure prophylaxis in a clinical study, HIV Prevention Trials Network 073. Antimicrob Agents Chemother. 2017 July;61(7). pii: e02743-16.
Key words: HIV, antiretroviral, HPTN, PrEP
PMID: 28438932

1. Amukele T. Africa Centers for Disease Control and Prevention: establishing regional integrated surveillance and laboratory networks for rapid disease detection and response, control, prevention, and clinical care in Africa. (Editorial) Afr J Lab Med. 2017;6(1) a638.
Key words: Africa, clinical care, surveillance

2. Cowan ML, Rosenthal DL, VandenBussche CJ. Improved risk stratification for patients with high?grade urothelial carcinoma following application of the Paris System for Reporting Urinary Cytology. Cancer. 2017 Jun;125(6):427-34.
Key words: cytology, urine, urothelial carcinoma, bladder cancer, paris system
PMID: 28272842

3. Kosmides AK, Sidhom JW, Fraser A, Bessell CA, Schneck JP. Dual targeting nanoparticle stimulates the immune system to inhibit tumor growth. ACS Nano. 2017 June;11(6):5417-29.
Key words: nanoparticle, immune system, tumor
PMID: 28589725

4. Lee J, Kazmi S, VandenBussche CJ, Ali SZ. Mesenchymal neoplasms of the head and neck: a cytopathologic analysis on fine needle aspiration. J Am Soc Pathol. 2017 Jun;6(3):105-13.
Key words: soft tissue neoplasms, head and neck, fine-needle aspiration, cytopathology
No PMID available

5. Lee S, Wang C, Pan HC, Shrestha S, Meyers C, Ding C, Shen J, Chen E, Lee M, Soo C, Ting K, James AW. Combining smoothened agonist and NEL-like protein-1 enhances bone healing. Plast Reconstr Surg. 2017 Jun;139(6):1385-96.
Key words: bone, bone healing, osteogenesis, Hedgehog signaling, Wnt signaling

6. Nguyen V, Myers CA, Yan N, Argarwal S, Levi B, James AW. BMP-2-induced bone formation and neural inflammation. J Orthop. 2017 June;14(2):252-6.
Key words: Bone, osteogenesis, bone regeneration BMP2, bone morphogenetic protein 2, neuritis

7. Poruk KE, Blackford AL, Weiss MJ, Cameron JL, He J, Goggins MG, Rasheed Z, Wolfgang CL, Wood LD. Circulating tumor cells expressing markers of tumor initiating cells predict poor survival and cancer recurrence in patients with pancreatic ductal adenocarcinoma. Clin Cancer Res. 2017 Jun;23(11):2681-90.
Key words: tumor cells, cancer, pancreatic ductal adenocarcinoma
PMID: 27789528

8. Sun M, Bell W, LaClair KD, Ling JP, Han H, Kageyama Y, Pletnikova O, Troncoso JC, Wong PC, Chen LL. Cryptic exon incorporation occurs in Alzheimer's brain lacking TDP-43 inclusion but exhibiting nuclear clearance of TDP-43. Acta Neuropathol. 2017 Jun;133(6):923-31.
Key words: Alzheimer's disease, ALS/FTD, hippocampal sclerosis, TDP-43 proteinopathy, cryptic exon, neurodegeneration
PMID: 28332094

9. Tosi L, Sridhara V, Yang Y, Guan D, Shpilker P, Segata N, Larman HB, Parekkadan B. Long-adapter single-strand oligonucleotide probes for the massively multiplexed cloning of kilobase genome regions. Nature Biomedical Engineering 2017 June;article number 0092:1-9
Key words: ORFeome, protein engineering, cloning, long read sequencing, high throughput
No PMID available

10. Vang R, Hannibal CG, Junge J, Frederiksen K, Kjaer SK, Kurman RJ. Long-term behavior of serous borderline tumors subdivided into atypical proliferative tumors and noninvasive low-grade carcinomas: a population-based clinicopathologic study of 942 cases. Am J Surg Pathol. 2017 Jun;41(6):725-37.
Key words: serous tumors, proliferative tumors, carcinoma
PMID: 28248817

11. Verrill C, Yilmaz A, Srigley JR, Amin MB, Compérat E, Egevad L, Ulbright TM, Tickoo SK, Berney DM, Epstein JI; Members of the International Society of Urological Pathology Testicular Tumor Panel. Reporting and staging of testicular germ cell tumors: The International Society of Urological Pathology (ISUP) Testicular Cancer Consultation Conference Recommendations. Am J Surg Pathol. 2017 Jun;41(6):e22-e32.
Key words: testis, germ cell tumors, embryonal carcinoma, seminoma, yolk sac tumor
PMID: 28368923

12. Yang S, Hu Y, Sokoll L, Zhang H. Simultaneous quantification of N- and O-glycans using a solid-phase method. Nat Protoc 2017 Jun;12(6):1229-44.
Key words: glycolysation, N-glycans
PMID: 28518173

13. Yang S, Zhang L, Thomas SN, Hu Y, Li S, Cipollo JF, Zhang H. Modification of sialic acids on solid-phase: accurate characterization of protein sialylation. Anal Chem. 2017 Jun;89(12):6330-5.
Key words: sialic acids, protein
No PMID available

Return to top of Publications - Pathology Archives

Search Publications
July 2020 articles:
Essential Information for Human Subjects Research Teams Related to COVID-19
Coronavirus Research Billing Notices and FAQ
Managing Investigational Product Returns from Research Participants
Update to Organization Policy on Registration of Clinical Trials
Changes in HSR Recertification
Update on Insurance and Research Participant Financial Responsibility Information Sheet: Signature No Longer Required
Change in JHM IRB Review Fees for Commercially-Funded Studies
Data and Safety Monitoring Board Training Manual Now Available
Good Clinical Practice (GCP) Fundamentals: Understanding and Applying GCP to Human Subject Research
Fee Schedule Adjustment for Hospital Services Charged to Clinical Trial Budgets
Changes to NIH-funded Human Subjects Research
Free Resources for Longitudinal Clinical Research Studies
JHM IRB Reliance Requests
Sharing Partnership for Innovative Research in Translation
Johns Hopkins Institute for Clinical and Translational Research
Johns Hopkins Clinical Research Network
Visit Animal Care and Use Committee Website
Current Classes
"Interinstitutional Assurance" Agreement
Health, Safety, and Environment (HSE) presents: Safety in Research Updates
COVID-19 Funding Opportunities
Searle Scholars Program
Michael J. Fox Foundation (MJFF) Challenge
Updated Guidance from NIH on COVID-19 Flexibilities for Applicants and Recipients
COVID-19 and Research Updates
Townhall Thursdays - Providing a Pulse on What's Happening in Research at JHU
New System to Request Outgoing Subawards
Point of Contact for NIH Loan Repayment Program
JHU SOM Update on NIH Policy on Foreign Involvement
Disclosure of Payments from Foreign Educational Institutions and Government Agencies
Institutional Letter of Support Required for Institutional Training Grant Applications
Notice to the Johns Hopkins Community Regarding the National Science Foundation Grant Reporting Requirement for Harassment Findings and Actions
Prohibited Mention of Prior Review for New Replacement Applications
NIH Policy on Foreign Component Involvement
NIH Policy: Foreign Components Added to a Grant to a Domestic or Foreign Organization
Why Project Outcomes Matter in your Interim and Final Research Performance Progress Report (RPPR)
NIH Matchmaker, A Tool For Finding Similar NIH Projects
NIH Video Tutorials on How to Apply for Grants

This Month's Departmental Listings

Upcoming Deadlines for July and September

Updates and Events at the Genetics Research Core Facilities


JHM AppointmentsEmployment @ JHM | Finding a Doctor | Disclaimer | Maps & Directions | Contact JHM 


                                                                                                                                                           The Web Center