Web notes  

November 2020

Medicine Archives

1. Bollinger RC, Thio CL, Sulkowski MS, McKenzie-White J, Thomas DL, Flexner C. Addressing the global burden of hepatitis B virus while developing long-acting injectables for the prevention and treatment of HIV. Lancet HIV. 2019 Dec 20. pii: S2352-3018(19)30342-X. doi: 10.1016/S2352-3018(19)30342-X. [Epub ahead of print]. PMID: 31870675.
Key words: HIV, HBV, hepatitis B virus, long acting injectable drugs, long acting drug formulations, PrEP, Pre-exposure prophylaxis, HBV treatment

1. Agrimi J, Spalletti C, Baroni, C, Keceli, G, Zhu G, Caragnano A, Casieri V. Obese mice exposed to psychosocial stress display cardiac and hippocampal dysfunction associated with local brain-derived neurotrophic factor depletion. EBioMedicine. 2019;47,384-401.
Key words: brain-heart axis, brain-derived neurotrophic factor (BDNF), obesity, psychosocial stress, left ventricle

2. Khoury SR, Evans NS, Ratchford EV. Exercise as medicine. Vasc Med. 2019 Aug;24(4):371-374. Epub 2019 May 30.
Key words: exercise, cardiovascular health
PMID: 31144595

1. Berlin A, Koski-Karell V, Page KR, Polk S. The right and left hands of the state - two patients at risk of deportation. N Engl J Med. 2019 July 18; 381(3):197-201. DOI: 10.1056/NEJMp1811607
Key words: immigration, immigrant health, deportation, undocumented patients, immigrant advocacy

2. Blaha MJ, Ratchford EV. Electronic cigarettes. Vasc Med. 2019;Jun;24(3):267-269.
Key words: Electronic cigarettes; smoking; smoking cessation; vaping
PMID: 30931840

3. Khoury SR, Evans NS, Ratchford EV. Exercise as medicine. Vasc Med. 2019; May 30:1358863X19850316.
Key words: exercise, cardiovascular health
PMID: 31144595

4. Kinikar A, Chandanwale A, Kadam D, Joshi S, Basavaraj A, Pardeshi G, Girish S, Shelke S, DeLuca A, Dhumal G, Golub J, Lokhande N, Gupte N, Gupta A, Bollinger R, Mave V. High risk for latent tuberculosis infection among medical residents and nursing students in India. PLoS ONE. 2019 July 8; 14(7): e0219131.
Key words: tuberculosis, latent tuberculosis, LTBI, healthcare worker, health worker safety, medical residents, nursing students, medical education

5. Mathews L, Subramanya V, Zhao D, Ouyang P, Vaidya D, Guallar E, Yeboah J, Herrington D, Hays AG, Budoff MJ, Michos ED. Endogenous sex hormones and endothelial function in postmenopausal women and men: the multi-ethnic study of atherosclerosis. J Womens Health. 2019 July; 28(7):900-909.
Key words: sex hormones, endothelial function

PMCID: PMC6613683

6. Nachman S, Townsend CL, Abrams EJ, Archary M, Capparelli E, Clayden P, Lockman S, Jean-Philippe P, Mayer K, Mirochnick M, McKenzie-White J, Struble K, Watts H, Flexner C. Long-acting or extended-release antiretroviral products for HIV treatment and prevention in infants, children, adolescents, and pregnant and breastfeeding women: knowledge gaps and research priorities. Lancet HIV. 2019 Jul 12. Epub ahead of print.
Key words: HIV, antiretroviral therapy, long-acting therapy, extended release therapy, ART, ARV
PMID: 31307946

7. Pallazola VA, Sathiyakumar V, Ogunmoroti O, Fashanu O, Jones SR, Santos RD, Toth PP, Bittencourt MS, Duncan BB, Lotufo PA, Bensenor IM, Blaha MJ, Martin SS. Impact of improved low-density lipoprotein cholesterol assessment on guideline classification in the modern treatment era - Results from a racially diverse Brazilian cross-sectional study. J Clin Lipidol. 2019;Jul 9. pii: S1933-2874(19)30234-X. doi: 10.1016/j.jacl.2019.07.002. [Epub ahead of print]
Key words: LDL cholesterol, guidelines, cardiovascular disease

PMID: 31383603

8. Plante TB, O'Kelly AC, Urrea B, MacFarlane ZT, Blumenthal RS, Charleston J, Miller ER, Appel LJ, Martin SS. User experience of instant blood pressure: exploring reasons for the popularity of an inaccurate mobile health app. NPJ Digit Med. 2018;Aug 10;1:31.
Key words: digital health, mobile health, smartphones, blood pressure, hypertension

PMID: 31304313

9. Russell KS, Yates DP, Kramer CM, Feller A, Mahling P, Colin L, Clough T, Wang T, LaPerna L, Patel A, Lawall H, Shennak MM, Fulmer J, Nikol S, Smith WB, Müller OJ, Ratchford EV, Basson CT. A randomized, placebo-controlled trial of canakinumab in patients with peripheral artery disease. Vasc Med. 2019;Jul 5:1358863X19859072. [Epub ahead of print]
Key words: canakinumab; interleukin-1?; intermittent claudication; peripheral artery disease (PAD)
PMID: 31277561

10. Shan R, Sarkar S, Martin SS. Digital health technology and mobile devices for the management of diabetes mellitus: state of the art. Diabetologia. 2019;Jun;62(6):877-87.
Key words: digital health, diabetes, precision medicine, smartphones, wearables

PMID: 30963188

11. Wu Y, Wang Q, Feng N, Granger JM, Anderson ME. Myocardial death and dysfunction after ischemia-reperfusion injury require CaMKII? oxidation. Sci Rep. 2019 Jun 26;9(1):9291.
Key words: ischemia-reperfusion injury; Ca2+/calmodulin-dependent protein kinase II; ATP sensitive K+ channel; heart

12. Yang WE, Shah LM, Spaulding EM, Wang J, Xun H, Weng D, Shan R, Wongvibulsin S, Marvel FA, Martin SS. The role of a clinician amid the rise of mobile health technology. J Am Med Inform Assoc. 2019;Aug 2. pii: ocz131.
Key words: digital health, mobile health, clinician-patient relationship, doctor-patient relationship
PMID: 31373364

1. Bettinotti MP, Ferriola D, Duke JL, Mosbruger TL, Tairis N, Jennings L, Kalman LV, Monos D. Characterization of 108 genomic DNA reference materials for 11 human leukocyte antigen loci: A GeT-RM collaborative project. J Mol Diagn. 2018 Sep;20(5):703-715.
Key words: human leukocyte antigen, DNA, genomics

2. Feng S, Bucuvalas JC, Demetris AJ, Burrell BE, Spain KM, Kanaparthi S, Magee JC, Ikle D, Lesniak A, Lozano JJ, Alonso EM, Bray RA, Bridges NE, Doo E, Gebel HM, Gupta NA, Himes RW, Jackson AM, Lobritto SJ, Mazariegos GV, Ng VL, Rand EB, Sherker AH, Sundaram S, Turmelle YP, Sanchez-Fueyo A. Evidence of chronic allograft injury in liver biopsies from long-term pediatric recipients of liver transplants. Gastroenterology. 2018 Aug 22. [Epub ahead of print]
Key words ALT; DSA; immune response; prognostic factor

3. Ruck JM, Jackson AM, Massie AB, Segev DL, Desai N, Garonzik-Wang J. Temporal changes in the Impact of HLA mismatching among pediatric kidney transplant recipients. Transplantation. 2018 Aug 20. [Epub ahead of print]

1. Atre S. Failure in TB control: why should the rapid diagnostic test bear the blame [correspondence]? Int J Tuberc Lung Dis. 2018 Sep 1;22(9):1109-1110. doi: 10.5588/ijtld.18.0314.
Key words: Tuberculosis, TB, disease control, diagnostics

2. Chida N, Brown C, Mathad J, Carpenter K, Nelson G, Schechter MC, Rebolledo PA, Fabre V, Cantillo DS, Longworth S, Amorosa V, Petrauskis C, Boulanger C, Cain N, Gupta A, McKenzie-White J, Bollinger R, Melia M. Developing an assessment framework for essential internal medicine subspecialty topics. J Grad Med Educ. 2018 Jun;10(3):331-335. doi: 10.4300/JGME-D-17-00377.1.
Key words: Medical school, medical education, graduate medical education, internal medicine, internal medicine subspecialty topics, educational assessment, medical residents

3. Chu N, Salguero AL, Liu AZ, Chen Z, Dempsey DR, Ficarro SB, Alexander WM, Marto JA, Li Y, Amzel LM, Gabelli SB, Cole PA. Akt kinase activation mechanisms revealed using protein semisynthesis. Cell. 2018 Aug 9;174(4):897-907.
Key words: X-ray crystal structure; bisubstrate analog; expressed protein ligation; kinase; mass spectrometry; peptide; phosphorylation; photocrosslinking

4. Martin SS, Giugliano RP, Murphy SA, Wasserman SM, Stein EA, Ceška R, López-Miranda J, Georgiev B, Lorenzatti AJ, Tikkanen MJ, Sever PS, Keech AC, Pedersen TR, Sabatine MS. Comparison of low-density lipoprotein cholesterol assessment by Martin/Hopkins estimation, Friedewald estimation, and preparative ultracentrifugation: Insights from the FOURIER trial. JAMA Cardiol. 2018 Aug 1;3(8):749-753.
Key words: low-density lipoprotein; cholesterol; accuracy; cardiovascular disease; PCSK9
PMID: 29898218

5. Nimkar S, Valvi C, Kadam D, Rewari BB, Kinikar A, Gupte N, Suryavanshi N, Deluca A, Shankar A, Golub J, Bollinger R, Gupta A, Marbaniang I, Mave V. Loss to follow?up and mortality among HIV?infected adolescents receiving antiretroviral therapy in Pune, India. HIV Medicine. 2018 Jul;19(6):395-402. doi: 10.1111/hiv.12605.
Key words: Loss to follow-up, HIV, adolescents, ART, India

6. Page KR, Grieb SD, Nieves-Lugo K, Yamanis T, Taylor H, Martinez O, Yamasaki Y, Limaye R, Davis W, Beyrer C, Zea MC. Enhanced immigration enforcement in the USA and the transnational continuity of HIV care for Latin American immigrants in deportation proceedings. Lancet HIV. 2018 Jul 6. pii: S2352-3018(18)30074-2.
Key words: immigration policy, immigration reform, immigration enforcement, Latinos, HIV, access to healthcare, continuity of care, patient retention

7. Plante TB, O'Kelly AC, Macfarlane ZT, Urrea B, Appel LJ, Miller Iii ER, Blumenthal RS, Martin SS. Trends in user ratings and reviews of a popular yet inaccurate blood pressure-measuring smartphone app. J Am Med Inform Assoc. 2018 Aug 1;25(8):1074-1079.
Key words: mobile health; digital health; smartphone app; blood pressure; ratings
PMID: 29878236

8. Sathiyakumar V, Park J, Quispe R, Elshazly MB, Michos ED, Banach M, Toth PP, Whelton SP, Blumenthal RS, Jones SR, Martin SS. Impact of novel LDL-C assessment on the utility of secondary non-HDL-C and apolipoprotein B targets in selected worldwide dyslipidemia guidelines. Circulation. 2018 Jul 17;138(3):244-254.
Key words: cholesterol; apolipoprotein B; targets; cardiovascular disease; guidelines

PMID: 29506984

1. Aronis AN, Berger RD, Calkins H, Chrispin J, Marine JE, Spragg DD, Tao S, Tandri T, Ashikaga H. Is human atrial fibrillation stochastic or deterministic? Insights from missing ordinal patterns and causal entropy-complexity plane analysis. Chaos. 2018 June; 28(6):063130.
Key words: information theory, stochastic processes, cardiac electrophysiology
PMID: 29960392

2. Ashikaga H, James RG. Inter-scale information flow as a surrogate for downward causation that maintains spiral waves. Chaos. 2018 July;28(7):075306.
Key words: information theory, pattern formation, statistical physics, cardiac electrophysiology
PMID: 30070515

3. Evans NS, Ratchford EV. Catheter-related venous thrombosis. Vasc Med. 2018;Aug 23(4):411-413.
Key words: catheter-related thrombosis; deep vein thrombosis (DVT); line-related thrombosis; superficial vein thrombosis (SVT); thrombosis; upper extremity DVT
PMID: 29952254

4. Inoue YY, Ipek EG, Khurram IM, Ciuffo L, Chrispin J, Zimmerman SL, Marine JE, Rickard J, MD; Spragg DD, Nazarian S, Kusano K, Lima JA, Berger RD, Calkins H, Ashikaga H. Relation of electrocardiographic left atrial abnormalities to risk of stroke in patients with atrial fibrillation. Am J Cardiol. 2018 July;122(2):242-247.
Key words: electrocardiogram, cardiac magnetic resonance, stroke
PMID: 29933926

5. Khoury SR, Ratchford EV. Hypertension. Vasc Med. 2018;Jun 23(3):293-297. doi: 10.1177/1358863X18764836. Epub 2018 Apr 13.
Key words: high blood pressure; hypertension
PMID: 29651931

6. Vaught AJ, Kovell LC, Szymanski L, Mayer SA, Seifert SM, Vaidya D, Murphy JD, Argani C, O'Kelly A, York S, Ouyang P, Mukherjee M, Zakaria S. The acute effects of preeclampsia with severe features on the heart. J Am Coll Cardiol. 2018 July 3;72(1):1-11.
Key words: diastolic dysfunction; echocardiography; pre-eclampsia; pulmonary edema; right ventricular systolic pressure; speckle tracking echocardiography

PMID: 29957219

1.Amoakwa K, Fashanu OE, Tibuakuu M, Zhao D, Guallar E, Whelton SP, O'Neal WT, Post WS, Budoff MJ, Michos ED. Resting heart rate and the incidence and progression of valvular calcium: The Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis. 2018 Jun;273:45-52. doi: 10.1016/j.atherosclerosis.2018.04.004.
Key words: heart rate, mitral annular calcium, aortic valve calcium, risk factors

2.Cardoso R, Kaul S, Okada DR, Blumenthal RS, Michos ED. A deeper dive into the CANTOS "Responders" Substudy. Mayo Clin Proc. 2018 May 22. pii: S0025-6196(18)30262-3. doi: 10.1016/j.mayocp.2018.04.003. [Epub ahead of print]
Key words: inflammation, cardiovascular disease, prevention, canakinumab

3.Subramanya V, Ambale-Venkatesh B, Ohyama Y, Zhao D, Nwabuo CC, Post WS, Guallar E, Ouyang P, Shah SJ, Allison MA, Ndumele CE, Vaidya D, Bluemke DA, Lima JA, Michos ED. Relation of sex hormone levels with prevalent and 10-year change in aortic distensibility assessed by MRI: The Multi-Ethnic Study of Atherosclerosis. Am J Hypertens. 2018 Jun 11; 31(7):774-783.
Key words: testosterone, sex hormones, aortic stiffness
No PMID available

4.Zhao D, Guallar E, Ballantyne CM, Hoogeveen RC, Blaha MJ, Michos ED. Usefulness of lipoprotein-associated phospholipase A2 Activity and C-Reactive Protein in identifying high risk smokers for atherosclerotic cardiovascular disease (From the ARIC Study). Am J Cardiol. 2018 May 1; 121(9):1056-1064. doi: 10.1016/j.amjcard.2018.01.020.
Key words: Smoking, inflammation, risk prediction

5.Zhao D, Guallar E, Ouyang P, Subramanya V, Vaidya D, Ndumele CE, Lima JA, Allison MA, Shah SJ, Bertoni AG, Budoff MJ, Post WS, Michos ED. Endogenous sex hormones and incident cardiovascular disease in post-menopausal women. J Am Coll Cardiol. 2018 Jun 5; 71(22):2555-2566. doi: 10.1016/j.jacc.2018.01.083.
Key words: testosterone, estradiol, cardiovascular events, heart failure, menopause

1. Hsu S, Kokkonen-Simon KM, Kirk JA, Kolb TM, Damico RL, Mathai SC, Mukherjee M, Shah AA, Wigley FM, Margulies KB, Hassoun PM, Halushka MK, Tedford RJ, Kass DA. Right ventricular myofilament functional differences in humans with systemic sclerosis-associated versus idiopathic pulmonary arterial hypertension. Circulation. 2018 May 29;137(22):2360-2370.
Key words: PKA; RV; myofilament; pulmonary arterial hypertension; scleroderma; tension

2. Nimkar S, Valvi C, Kadam D, Rewari BB, Kinikar A, Gupte N, Suryavanshi N, Deluca A, Shankar A, Golub J, Bollinger R, Gupta A, Marbaniang I, Mave V. Loss to follow-up and mortality among HIV-infected adolescents receiving antiretroviral therapy in Pune, India. HIV Medicine. 2018; 2018 Jul;19(6):395-402.
Key words: HIV/AIDS; India; adolescents; loss to follow-up; mortality
PMID: 29573312

3. Subramanya V, Ambale-Venkatesh B, Ohyama Y, Zhao D, Nwabuo CC, Post WS, Guallar E, Ouyang P, Shah SJ, Allison MA, Ndumele CE, Vaidya D, Bluemke DA, Lima JA, Michos ED. Relation of sex hormone levels with prevalent and 10-year change in aortic distensibility assessed by MRI: The Multi-Ethnic Study of Atherosclerosis. Am J Hypertens. 2018 Jun 11;31(7):774-783.
Key words: testosterone, sex hormones, aortic stiffness

4. Tibuakuu M, Kianoush S, DeFilippis AP, McEvoy JW, Zhao D, Guallar E, Ballantyne CM, Hoogeveen RC, Blaha MJ, Michos ED. Usefulness of lipoprotein-associated phospholipase A2 activity and C-reactive protein in identifying high risk smokers for atherosclerotic cardiovascular disease (From the ARIC Study). Am J Cardiol. 2018 May 1;121(9):1056-1064.
Key words: smoking, inflammation, risk prediction

5. Wang S, Venkatraman V, Crowgey EL, Liu T, Fu Z, Holewinski RJ, Ranek MJJ, Kass DA, O'Rourke B, Van Eyk JE. Protein S-Nitrosylation Controls Glycogen Synthase Kinase 3ß Function Independent of its Phosphorylation State. Circ Res. 2018 May 25;122(11):1517-1531.
Key words: glycogen synthase kinase 3 beta; S-nitrosylation; animal model cardiovascular disease; cell signaling; kinase-substrates interactome; nuclear translocation; proteomics; redox regulation

1. Ajbani K, Kazi M, Tornheim J, Naik S, Soman R, Shetty A, Rodrigues A. Pyrosequencing to resolve discrepant Xpert MTB/RIF and Mycobacterial Growth Indicator Tube 960. Lung India. 2018 Mar-Apr; 35(2): 168–170.
Key words: Culture; Xpert; discrepancy; pyrosequencing


2. Evans NS, Ratchford EV. Superficial vein thrombosis. Vasc Med. 2018 Apr;23(2):187-189. doi: 10.1177/1358863X18755928.
Key words: phlebitis; superficial thrombophlebitis; superficial vein thrombosis (SVT); superficial venous thrombosis; venous thromboembolism (VTE)

3. Hauspurg A, Ying W, Hubel CA, Michos ED, Ouyang P. Adverse pregnancy outcomes and future maternal cardiovascular disease. Clin Cardiol. 2018 Feb;41(2):239-246.
Key words: pregnancy, gestational diabetes, pre-eclampsia, cardiovascular risk, women

4. Nakamura T, Zhu G, Ranek MJ, Kokkonen-Simon K, Zhang M, Kim GE, Tsujita K, Kass DA. Prevention of PKG-1a oxidation suppresses antihypertrophic/antifibrotic effects from PDE5 inhibition but not sGC stimulation. Circ Heart Fail. 2018 Mar;11(3):e004740. doi: 10.1161/CIRCHEARTFAILURE.117.004740.
Key words: cyclic GMP; cyclic GMP-dependent protein kinases; heart failure; hypertrophy; pharmacology

5. Philogene MC, Zhou S, Lonze BE, Bagnasco S, Alasfar S, Montgomery RA, Kraus E, Jackson AM, Leffell MS, Zachary AA. Pre-transplant screening for non-HLA antibodies: who should be tested? Hum Immunol. 2018 Apr;79(4):195-202.
Key words: Angiotensin II type 1 receptor antibody; Anti-endothelial cell antibodies; High immunologic risk patients; Kidney allograft dysfunction; Non-HLA antibodies

6. Seth R, Akinboyo I, Chhabra A, Qaiyum Y, Shet A, Gupte N, Jain AK, Jain SK. Mobile phone incentives for childhood immunizations in rural India. Pediatrics. 2018 Apr;141(4).
Key words: Pediatrics; children; vaccines; immunization; resource-poor settings; LMIC; low and middle income countries; India; technology; mobile phones; cellphones; incentives
PMID: 29540571

1. Aronis KN, Ashikaga H. Impact of number of co-existing rotors and inter-electrode distance on accuracy of rotor localization. J Electrocardiol. 2018; 51: 82-91.
Key words: atrial fibrillation, catheter ablation, spiral waves, rotors

2. Ashikaga H, Asgari-Targhi A. Locating order-disorder phase transition in a cardiac system. Sci Rep. 2018; 8: 1967.
Key words: fibrillation, complex systems, information theory, phase transition

3. Atre S. How feasible is pharmaceutical regulation in India? The Lancet Global Health. 2018 Feb;6(2);e143.
Key words: antimicrobial resistance, antibiotic resistance, antibiotic stewardship, antibiotic use, antibiotic misuse, global health
PMID: 29389535

4. Mathews L, Ogunmoroti O, Nasir K, Blumenthal RS, Utuama OA, Rouseff M, Das S, Veledar E, Feldman T, Agatston A, Zhao D, Michos ED. Psychological Factors and Their Association with Ideal Cardiovascular Health Among Women and Men. J Womens Health (Larchmt). 2018 Jan 29. doi: 10.1089/jwh.2017.6563. [Epub ahead of print]
Key words: stress, depression, cardiovascular health, sex differences

5. Suryavanshi N, Naik S, Waghmare S, Gupte N, Khan S, Mave V, Deluca A, Gupta A, Golub J, Bollinger RC, Shankar A. Gender-based violence screening methods preferred by women visiting a public hospital in Pune, India. BMC Womens Health. 2018;18(1): e19.
Key words: Domestic violence, gender-based violence, domestic violence screening, counseling, HIV

6. Tibuakuu M, Zhao D, Saxena A, Brown TT, Jacobson LP, Palella FJ Jr., Witt MD, Koletar SL, Margolick JB, Guallar E, Korada SKC, Budoff MJ, Post WS, Michos ED. Low thigh muscle mass is associated with coronary artery stenosis among HIV-infected and HIV-uninfected men: The Multicenter AIDS Cohort Study (MACS). J Cardiovasc Comput Tomogr. 2018 Jan 30. pii: S1934-5925(18)30019-4. doi: 10.1016/j.jcct.2018.01.007. [Epub ahead of print]
Key words: sarcopenia, coronary artery disease, HIV-infection

1. Aronis KN, Zhao D, Hoogeveen RC, Alonso A, Ballantyne CM, Guallar E, Jones SR, Martin SS, Nazarian S, Steffen BT, Virani SS, Michos ED. Associations of lipoprotein(a) levels with incident atrial fibrillation and ischemic stroke: The ARIC (Atherosclerosis Risk in Communities) Study. J Am Heart Assoc. 2017 Dec 15;6(12).
Key words: lipoprotein(a), atrial fibrillation, stroke

2. Elf JL, Kinikar A, Khadse S, Mave V, Gupte N, Kulkarni V, Patekar S, Raichur P, Cohen J, Breysse PN, Gupta A, Golub JE. Secondhand smoke exposure and validity of self-report in low-income women and children in India. Pediatrics. 2018 Jan;141(Suppl 1):S118-S129. doi: 10.1542/peds.2017-1026O.
Key words: secondhand smoke, air quality, environmental health, smoking, cigarettes, nicotine, tobacco, LMIC, India, children, women

3. Gilotra NA, Princewill O, Marino B, Okwuosa IS, Chasler J, Almansa J, Cummings A, Rhodes P, Chambers J, Cuomo K, Russell SD. Efficacy of intravenous furosemide versus a novel, ph-neutral furosemide formulation administered subcutaneously in outpatients with worsening heart failure. JACC Heart Fail. 2018 Jan;6(1):65-70. PMID: 29226816
Key words: congestion; disease management; diuretic; drug delivery; subcutaneous

4. Grabowski MK, Serwadda DM, Gray RH, Nakigozi G, Kigozi G, Kagaayi J, Ssekubugu R, Nalugoda F, Lessler J, Lutalo T, Galiwango RM, Makumbi F, Kong X, Kabatesi D, Alamo ST, Wiersma S, Sewankambo NK, Tobian AAR, Laeyendecker O, Quinn TC, Reynolds SJ, Wawer MJ, Chang LW, for the Rakai Health Sciences Program. HIV prevention efforts and incidence of HIV in Uganda. N Engl J Med. 2017 Nov 30;377:2154-2166.
Key words: HIV, HIV incidence, Combination HIV prevention, CHP, antiretroviral therapy, ART, Uganda, prevention

5. McDonald TJW, Ratchford EV, Henry-Barron BJ, Kossoff EH, Cervenka MC. Impact of the modified Atkins diet on cardiovascular health in adults with epilepsy. Epilepsy Behav. 2017 Dec 15;79:82-86. doi: 10.1016/j.yebeh.2017.10.035. [Epub ahead of print]
Key words: carotid intima-media thickness, epilepsy, ketogenic diet, low-density-lipoprotein, modified Atkins diet

6. Michos ED, Blumenthal RS. Treatment concentration of high-sensitivity C-reactive protein. Lancet. 2017 Nov 13. pii: S0140-6736(17)32865-9. doi: 10.1016/S0140-6736(17)32865-9. [Epub ahead of print]
Key words: C-reactive protein, canakinumab, clinical trial, cardiovascular outcomes, editorial

7. Michos ED, Blaha MJ, Blumenthal RS. Use of the Coronary Artery Calcium Score in discussion of initiation of statin therapy in primary prevention. Mayo Clin Proc. 2017 Dec;92(12):1831-1841.
Key words: coronary artery calcium, cardiovascular risk assessment, statins, review

8. Moliterno A, Ratchford EV. Shedding new light on the magnitude of thrombosis risk in patients with myeloproliferative neoplasms. Ann Intern Med 2018, published online 1/16/2018. DOI: 10.7326/M17-3153.
Key words: thrombosis, myeloproliferative neoplasm

9. Mukherjee M, Mercurio V, Tedford RJ, Shah AA, Hsu S, Mullin CJ, Sato T, Damico R, Kolb TM, Mathai SC, Hassoun PM. Right ventricular longitudinal strain is diminished in systemic sclerosis compared to idiopathic pulmonary arterial hypertension. Eur Respir J. 2017 Nov 22;50(5).
Key words: pulmonary hypertension, right ventricle, systemic sclerosis
PMID: 29167303

10. Robinson M, Kadam D, Kagal A, Khadse S, Kinikar A, Valvi C, Basavaraj A, Bharadwaj R, Marbaniang I, Kanade S, Raichur P, Sachs J, Klein E, Cosgrove S, Gupta A, Mave V. Antibiotic utilization and the role of suspected and diagnosed mosquito borne illness among adults and children with acute febrile illness in Pune, India. Clin Infect Dis. 2017 Dec 4. doi: 10.1093/cid/cix1059. PMID 29211830. [Epub ahead of print]
Key words: Antibiotic usage; India; acute febrile illness; diagnosis; vector-borne

11. Subramanya V, Zhao D, Ouyang P, Lima JA, Vaidya D, Ndumele CE, Bluemke DA, Shah SJ, Guallar E, Nwabuo CC, Allison MA, Heckbert SR, Post WS, Michos ED. Sex hormone levels and change in left ventricular structure among men and post-menopausal women: The Multi-Ethnic Study of Atherosclerosis (MESA). Maturitas. 2018 Feb;108:37-44.
Key words: sex hormones, left ventricular mass, cardiac remodeling, cardiac MRI

12. Tibuakuu M, Jones MR, Navas-Acien A, Zhao D, Guallar E, Gassett AJ, Sheppard L, Budoff MJ, Kaufman JD, Michos ED. Exposure to ambient air pollution and calcification of the mitral annulus and aortic valve: the multi-ethnic study of atherosclerosis (MESA). Environ Health. 2017 Dec 21;16(1):133.
Key words: air pollution, mitral annular calcium, aortic valve calcium, computed tomography

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November 2020 articles:
Essential Information for Human Subjects Research Teams Related to COVID-19
Coronavirus Research Billing Notices and FAQ
Storytelling Series: Dissemination of Research Through Storytelling
Research Billing Buzz eNewsletter
Managing Investigational Product Returns from Research Participants
Update to Organization Policy on Registration of Clinical Trials
Changes in HSR Recertification
Update on Insurance and Research Participant Financial Responsibility Information Sheet: Signature No Longer Required
Change in JHM IRB Review Fees for Commercially-Funded Studies
Data and Safety Monitoring Board Training Manual Now Available
Good Clinical Practice (GCP) Fundamentals: Understanding and Applying GCP to Human Subject Research
Fee Schedule Adjustment for Hospital Services Charged to Clinical Trial Budgets
Changes to NIH-funded Human Subjects Research
Free Resources for Longitudinal Clinical Research Studies
JHM IRB Reliance Requests
Sharing Partnership for Innovative Research in Translation
Johns Hopkins Institute for Clinical and Translational Research
Johns Hopkins Clinical Research Network
Visit Animal Care and Use Committee Website
Current Classes
"Interinstitutional Assurance" Agreement
Health, Safety, and Environment (HSE) presents: Safety in Research Updates
COVID-19 Funding Opportunities
The Fisher Center Discovery Program 2021 - Request for Applications
Michael J. Fox Foundation (MJFF) Challenge
Updated Guidance from NIH on COVID-19 Flexibilities for Applicants and Recipients
COVID-19 and Research Updates
New System to Request Outgoing Subawards
Point of Contact for NIH Loan Repayment Program
JHU SOM Update on NIH Policy on Foreign Involvement
Disclosure of Payments from Foreign Educational Institutions and Government Agencies
Institutional Letter of Support Required for Institutional Training Grant Applications
Notice to the Johns Hopkins Community Regarding the National Science Foundation Grant Reporting Requirement for Harassment Findings and Actions
Prohibited Mention of Prior Review for New Replacement Applications
NIH Policy on Foreign Component Involvement
NIH Policy: Foreign Components Added to a Grant to a Domestic or Foreign Organization
Why Project Outcomes Matter in your Interim and Final Research Performance Progress Report (RPPR)
NIH Matchmaker, A Tool For Finding Similar NIH Projects
NIH Video Tutorials on How to Apply for Grants

This Month's Departmental Listings

Upcoming Deadlines for November, December and January

Updates and November Events at the Genetics Research Core Facilities


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