Web notes  

October 2018

Medicine Archives

1. Aronis AN, Berger RD, Calkins H, Chrispin J, Marine JE, Spragg DD, Tao S, Tandri T, Ashikaga H. Is human atrial fibrillation stochastic or deterministic? Insights from missing ordinal patterns and causal entropy-complexity plane analysis. Chaos. 2018 June; 28(6):063130.
Key words: information theory, stochastic processes, cardiac electrophysiology
PMID: 29960392

2. Ashikaga H, James RG. Inter-scale information flow as a surrogate for downward causation that maintains spiral waves. Chaos. 2018 July;28(7):075306.
Key words: information theory, pattern formation, statistical physics, cardiac electrophysiology
PMID: 30070515

3. Evans NS, Ratchford EV. Catheter-related venous thrombosis. Vasc Med. 2018;Aug 23(4):411-413.
Key words: catheter-related thrombosis; deep vein thrombosis (DVT); line-related thrombosis; superficial vein thrombosis (SVT); thrombosis; upper extremity DVT
PMID: 29952254

4. Inoue YY, Ipek EG, Khurram IM, Ciuffo L, Chrispin J, Zimmerman SL, Marine JE, Rickard J, MD; Spragg DD, Nazarian S, Kusano K, Lima JA, Berger RD, Calkins H, Ashikaga H. Relation of electrocardiographic left atrial abnormalities to risk of stroke in patients with atrial fibrillation. Am J Cardiol. 2018 July;122(2):242-247.
Key words: electrocardiogram, cardiac magnetic resonance, stroke
PMID: 29933926

5. Khoury SR, Ratchford EV. Hypertension. Vasc Med. 2018;Jun 23(3):293-297. doi: 10.1177/1358863X18764836. Epub 2018 Apr 13.
Key words: high blood pressure; hypertension
PMID: 29651931

6. Vaught AJ, Kovell LC, Szymanski L, Mayer SA, Seifert SM, Vaidya D, Murphy JD, Argani C, O'Kelly A, York S, Ouyang P, Mukherjee M, Zakaria S. The acute effects of preeclampsia with severe features on the heart. J Am Coll Cardiol. 2018 July 3;72(1):1-11.
Key words: diastolic dysfunction; echocardiography; pre-eclampsia; pulmonary edema; right ventricular systolic pressure; speckle tracking echocardiography

PMID: 29957219

1.Amoakwa K, Fashanu OE, Tibuakuu M, Zhao D, Guallar E, Whelton SP, O'Neal WT, Post WS, Budoff MJ, Michos ED. Resting heart rate and the incidence and progression of valvular calcium: The Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis. 2018 Jun;273:45-52. doi: 10.1016/j.atherosclerosis.2018.04.004.
Key words: heart rate, mitral annular calcium, aortic valve calcium, risk factors

2.Cardoso R, Kaul S, Okada DR, Blumenthal RS, Michos ED. A deeper dive into the CANTOS "Responders" Substudy. Mayo Clin Proc. 2018 May 22. pii: S0025-6196(18)30262-3. doi: 10.1016/j.mayocp.2018.04.003. [Epub ahead of print]
Key words: inflammation, cardiovascular disease, prevention, canakinumab

3.Subramanya V, Ambale-Venkatesh B, Ohyama Y, Zhao D, Nwabuo CC, Post WS, Guallar E, Ouyang P, Shah SJ, Allison MA, Ndumele CE, Vaidya D, Bluemke DA, Lima JA, Michos ED. Relation of sex hormone levels with prevalent and 10-year change in aortic distensibility assessed by MRI: The Multi-Ethnic Study of Atherosclerosis. Am J Hypertens. 2018 Jun 11; 31(7):774-783.
Key words: testosterone, sex hormones, aortic stiffness
No PMID available

4.Zhao D, Guallar E, Ballantyne CM, Hoogeveen RC, Blaha MJ, Michos ED. Usefulness of lipoprotein-associated phospholipase A2 Activity and C-Reactive Protein in identifying high risk smokers for atherosclerotic cardiovascular disease (From the ARIC Study). Am J Cardiol. 2018 May 1; 121(9):1056-1064. doi: 10.1016/j.amjcard.2018.01.020.
Key words: Smoking, inflammation, risk prediction

5.Zhao D, Guallar E, Ouyang P, Subramanya V, Vaidya D, Ndumele CE, Lima JA, Allison MA, Shah SJ, Bertoni AG, Budoff MJ, Post WS, Michos ED. Endogenous sex hormones and incident cardiovascular disease in post-menopausal women. J Am Coll Cardiol. 2018 Jun 5; 71(22):2555-2566. doi: 10.1016/j.jacc.2018.01.083.
Key words: testosterone, estradiol, cardiovascular events, heart failure, menopause

1. Hsu S, Kokkonen-Simon KM, Kirk JA, Kolb TM, Damico RL, Mathai SC, Mukherjee M, Shah AA, Wigley FM, Margulies KB, Hassoun PM, Halushka MK, Tedford RJ, Kass DA. Right ventricular myofilament functional differences in humans with systemic sclerosis-associated versus idiopathic pulmonary arterial hypertension. Circulation. 2018 May 29;137(22):2360-2370.
Key words: PKA; RV; myofilament; pulmonary arterial hypertension; scleroderma; tension

2. Nimkar S, Valvi C, Kadam D, Rewari BB, Kinikar A, Gupte N, Suryavanshi N, Deluca A, Shankar A, Golub J, Bollinger R, Gupta A, Marbaniang I, Mave V. Loss to follow-up and mortality among HIV-infected adolescents receiving antiretroviral therapy in Pune, India. HIV Medicine. 2018; 2018 Jul;19(6):395-402.
Key words: HIV/AIDS; India; adolescents; loss to follow-up; mortality
PMID: 29573312

3. Subramanya V, Ambale-Venkatesh B, Ohyama Y, Zhao D, Nwabuo CC, Post WS, Guallar E, Ouyang P, Shah SJ, Allison MA, Ndumele CE, Vaidya D, Bluemke DA, Lima JA, Michos ED. Relation of sex hormone levels with prevalent and 10-year change in aortic distensibility assessed by MRI: The Multi-Ethnic Study of Atherosclerosis. Am J Hypertens. 2018 Jun 11;31(7):774-783.
Key words: testosterone, sex hormones, aortic stiffness

4. Tibuakuu M, Kianoush S, DeFilippis AP, McEvoy JW, Zhao D, Guallar E, Ballantyne CM, Hoogeveen RC, Blaha MJ, Michos ED. Usefulness of lipoprotein-associated phospholipase A2 activity and C-reactive protein in identifying high risk smokers for atherosclerotic cardiovascular disease (From the ARIC Study). Am J Cardiol. 2018 May 1;121(9):1056-1064.
Key words: smoking, inflammation, risk prediction

5. Wang S, Venkatraman V, Crowgey EL, Liu T, Fu Z, Holewinski RJ, Ranek MJJ, Kass DA, O'Rourke B, Van Eyk JE. Protein S-Nitrosylation Controls Glycogen Synthase Kinase 3ß Function Independent of its Phosphorylation State. Circ Res. 2018 May 25;122(11):1517-1531.
Key words: glycogen synthase kinase 3 beta; S-nitrosylation; animal model cardiovascular disease; cell signaling; kinase-substrates interactome; nuclear translocation; proteomics; redox regulation

1. Ajbani K, Kazi M, Tornheim J, Naik S, Soman R, Shetty A, Rodrigues A. Pyrosequencing to resolve discrepant Xpert MTB/RIF and Mycobacterial Growth Indicator Tube 960. Lung India. 2018 Mar-Apr; 35(2): 168–170.
Key words: Culture; Xpert; discrepancy; pyrosequencing


2. Evans NS, Ratchford EV. Superficial vein thrombosis. Vasc Med. 2018 Apr;23(2):187-189. doi: 10.1177/1358863X18755928.
Key words: phlebitis; superficial thrombophlebitis; superficial vein thrombosis (SVT); superficial venous thrombosis; venous thromboembolism (VTE)

3. Hauspurg A, Ying W, Hubel CA, Michos ED, Ouyang P. Adverse pregnancy outcomes and future maternal cardiovascular disease. Clin Cardiol. 2018 Feb;41(2):239-246.
Key words: pregnancy, gestational diabetes, pre-eclampsia, cardiovascular risk, women

4. Nakamura T, Zhu G, Ranek MJ, Kokkonen-Simon K, Zhang M, Kim GE, Tsujita K, Kass DA. Prevention of PKG-1a oxidation suppresses antihypertrophic/antifibrotic effects from PDE5 inhibition but not sGC stimulation. Circ Heart Fail. 2018 Mar;11(3):e004740. doi: 10.1161/CIRCHEARTFAILURE.117.004740.
Key words: cyclic GMP; cyclic GMP-dependent protein kinases; heart failure; hypertrophy; pharmacology

5. Philogene MC, Zhou S, Lonze BE, Bagnasco S, Alasfar S, Montgomery RA, Kraus E, Jackson AM, Leffell MS, Zachary AA. Pre-transplant screening for non-HLA antibodies: who should be tested? Hum Immunol. 2018 Apr;79(4):195-202.
Key words: Angiotensin II type 1 receptor antibody; Anti-endothelial cell antibodies; High immunologic risk patients; Kidney allograft dysfunction; Non-HLA antibodies

6. Seth R, Akinboyo I, Chhabra A, Qaiyum Y, Shet A, Gupte N, Jain AK, Jain SK. Mobile phone incentives for childhood immunizations in rural India. Pediatrics. 2018 Apr;141(4).
Key words: Pediatrics; children; vaccines; immunization; resource-poor settings; LMIC; low and middle income countries; India; technology; mobile phones; cellphones; incentives
PMID: 29540571

1. Aronis KN, Ashikaga H. Impact of number of co-existing rotors and inter-electrode distance on accuracy of rotor localization. J Electrocardiol. 2018; 51: 82-91.
Key words: atrial fibrillation, catheter ablation, spiral waves, rotors

2. Ashikaga H, Asgari-Targhi A. Locating order-disorder phase transition in a cardiac system. Sci Rep. 2018; 8: 1967.
Key words: fibrillation, complex systems, information theory, phase transition

3. Atre S. How feasible is pharmaceutical regulation in India? The Lancet Global Health. 2018 Feb;6(2);e143.
Key words: antimicrobial resistance, antibiotic resistance, antibiotic stewardship, antibiotic use, antibiotic misuse, global health
PMID: 29389535

4. Mathews L, Ogunmoroti O, Nasir K, Blumenthal RS, Utuama OA, Rouseff M, Das S, Veledar E, Feldman T, Agatston A, Zhao D, Michos ED. Psychological Factors and Their Association with Ideal Cardiovascular Health Among Women and Men. J Womens Health (Larchmt). 2018 Jan 29. doi: 10.1089/jwh.2017.6563. [Epub ahead of print]
Key words: stress, depression, cardiovascular health, sex differences

5. Suryavanshi N, Naik S, Waghmare S, Gupte N, Khan S, Mave V, Deluca A, Gupta A, Golub J, Bollinger RC, Shankar A. Gender-based violence screening methods preferred by women visiting a public hospital in Pune, India. BMC Womens Health. 2018;18(1): e19.
Key words: Domestic violence, gender-based violence, domestic violence screening, counseling, HIV

6. Tibuakuu M, Zhao D, Saxena A, Brown TT, Jacobson LP, Palella FJ Jr., Witt MD, Koletar SL, Margolick JB, Guallar E, Korada SKC, Budoff MJ, Post WS, Michos ED. Low thigh muscle mass is associated with coronary artery stenosis among HIV-infected and HIV-uninfected men: The Multicenter AIDS Cohort Study (MACS). J Cardiovasc Comput Tomogr. 2018 Jan 30. pii: S1934-5925(18)30019-4. doi: 10.1016/j.jcct.2018.01.007. [Epub ahead of print]
Key words: sarcopenia, coronary artery disease, HIV-infection

1. Aronis KN, Zhao D, Hoogeveen RC, Alonso A, Ballantyne CM, Guallar E, Jones SR, Martin SS, Nazarian S, Steffen BT, Virani SS, Michos ED. Associations of lipoprotein(a) levels with incident atrial fibrillation and ischemic stroke: The ARIC (Atherosclerosis Risk in Communities) Study. J Am Heart Assoc. 2017 Dec 15;6(12).
Key words: lipoprotein(a), atrial fibrillation, stroke

2. Elf JL, Kinikar A, Khadse S, Mave V, Gupte N, Kulkarni V, Patekar S, Raichur P, Cohen J, Breysse PN, Gupta A, Golub JE. Secondhand smoke exposure and validity of self-report in low-income women and children in India. Pediatrics. 2018 Jan;141(Suppl 1):S118-S129. doi: 10.1542/peds.2017-1026O.
Key words: secondhand smoke, air quality, environmental health, smoking, cigarettes, nicotine, tobacco, LMIC, India, children, women

3. Gilotra NA, Princewill O, Marino B, Okwuosa IS, Chasler J, Almansa J, Cummings A, Rhodes P, Chambers J, Cuomo K, Russell SD. Efficacy of intravenous furosemide versus a novel, ph-neutral furosemide formulation administered subcutaneously in outpatients with worsening heart failure. JACC Heart Fail. 2018 Jan;6(1):65-70. PMID: 29226816
Key words: congestion; disease management; diuretic; drug delivery; subcutaneous

4. Grabowski MK, Serwadda DM, Gray RH, Nakigozi G, Kigozi G, Kagaayi J, Ssekubugu R, Nalugoda F, Lessler J, Lutalo T, Galiwango RM, Makumbi F, Kong X, Kabatesi D, Alamo ST, Wiersma S, Sewankambo NK, Tobian AAR, Laeyendecker O, Quinn TC, Reynolds SJ, Wawer MJ, Chang LW, for the Rakai Health Sciences Program. HIV prevention efforts and incidence of HIV in Uganda. N Engl J Med. 2017 Nov 30;377:2154-2166.
Key words: HIV, HIV incidence, Combination HIV prevention, CHP, antiretroviral therapy, ART, Uganda, prevention

5. McDonald TJW, Ratchford EV, Henry-Barron BJ, Kossoff EH, Cervenka MC. Impact of the modified Atkins diet on cardiovascular health in adults with epilepsy. Epilepsy Behav. 2017 Dec 15;79:82-86. doi: 10.1016/j.yebeh.2017.10.035. [Epub ahead of print]
Key words: carotid intima-media thickness, epilepsy, ketogenic diet, low-density-lipoprotein, modified Atkins diet

6. Michos ED, Blumenthal RS. Treatment concentration of high-sensitivity C-reactive protein. Lancet. 2017 Nov 13. pii: S0140-6736(17)32865-9. doi: 10.1016/S0140-6736(17)32865-9. [Epub ahead of print]
Key words: C-reactive protein, canakinumab, clinical trial, cardiovascular outcomes, editorial

7. Michos ED, Blaha MJ, Blumenthal RS. Use of the Coronary Artery Calcium Score in discussion of initiation of statin therapy in primary prevention. Mayo Clin Proc. 2017 Dec;92(12):1831-1841.
Key words: coronary artery calcium, cardiovascular risk assessment, statins, review

8. Moliterno A, Ratchford EV. Shedding new light on the magnitude of thrombosis risk in patients with myeloproliferative neoplasms. Ann Intern Med 2018, published online 1/16/2018. DOI: 10.7326/M17-3153.
Key words: thrombosis, myeloproliferative neoplasm

9. Mukherjee M, Mercurio V, Tedford RJ, Shah AA, Hsu S, Mullin CJ, Sato T, Damico R, Kolb TM, Mathai SC, Hassoun PM. Right ventricular longitudinal strain is diminished in systemic sclerosis compared to idiopathic pulmonary arterial hypertension. Eur Respir J. 2017 Nov 22;50(5).
Key words: pulmonary hypertension, right ventricle, systemic sclerosis
PMID: 29167303

10. Robinson M, Kadam D, Kagal A, Khadse S, Kinikar A, Valvi C, Basavaraj A, Bharadwaj R, Marbaniang I, Kanade S, Raichur P, Sachs J, Klein E, Cosgrove S, Gupta A, Mave V. Antibiotic utilization and the role of suspected and diagnosed mosquito borne illness among adults and children with acute febrile illness in Pune, India. Clin Infect Dis. 2017 Dec 4. doi: 10.1093/cid/cix1059. PMID 29211830. [Epub ahead of print]
Key words: Antibiotic usage; India; acute febrile illness; diagnosis; vector-borne

11. Subramanya V, Zhao D, Ouyang P, Lima JA, Vaidya D, Ndumele CE, Bluemke DA, Shah SJ, Guallar E, Nwabuo CC, Allison MA, Heckbert SR, Post WS, Michos ED. Sex hormone levels and change in left ventricular structure among men and post-menopausal women: The Multi-Ethnic Study of Atherosclerosis (MESA). Maturitas. 2018 Feb;108:37-44.
Key words: sex hormones, left ventricular mass, cardiac remodeling, cardiac MRI

12. Tibuakuu M, Jones MR, Navas-Acien A, Zhao D, Guallar E, Gassett AJ, Sheppard L, Budoff MJ, Kaufman JD, Michos ED. Exposure to ambient air pollution and calcification of the mitral annulus and aortic valve: the multi-ethnic study of atherosclerosis (MESA). Environ Health. 2017 Dec 21;16(1):133.
Key words: air pollution, mitral annular calcium, aortic valve calcium, computed tomography

1. Ahmed HM, Al-Mallah MH, Keteyian SJ, Brawner CA, Ehrman JK, Zhao D, Guallar E, Blaha MJ, Michos ED. Sex-specific maximum predicted heart rate and its prognosis for mortality and MI. Med Sci Sports Exerc. 2017 Aug; 49(8):1704-1710.
Key words: Exercise stress testing, women, peak heart rate, cardiovascular disease

2. Ding X, Hao Q, Yang M, Chen T, Chen S, Yue J, Leng SX, Dong B. Polymorphism rs189037C > T in the promoter region of the ATM gene may associate with reduced risk of T2DM in older adults in China: a case control study. BMC Med Genet. 2017 Aug 14;18(1):84. doi: 10.1186/s12881-017-0446-z.
Key words: Ataxia telangiectasia mutated; Coronary artery disease; Single nucleoside polymorphism; Type 2 diabetes mellitus

3. Gilotra NA, Bhonsale A, James CA, Te Riele ASJ, Murray B, Tichnell C, Sawant A, Ong CS, Judge DP, Russell SD, Calkins H, Tedford RJ. Heart failure is common and under-recognized in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia. Circ Heart Fail. 2017 Sep;10(9).
Key words: arrhythmias, cardiomyopathies, dyspnea, fatigue, heart failure
PMID: 28874384

4. Gilotra NA, Tedford RJ, Wittstein IS, Yenokyan G, Sharma K, Russell SD, Silber HA. Usefulness of pulse amplitude changes during the Valsalva maneuver measured using finger photoplethysmography to identify elevated pulmonary capillary wedge pressure in patients with heart failure. Am J Cardiol. 2017 Sep 15;120(6):966-972.
Key words: filling pressure, noninvasive, readmission, device
PMID: 28754567

5. Jan de Boer IH, Bangalore S, Benetos A, Davis AM, Michos ED, Muntner P, Rossing P, Zoungas S, Bakris G. Diabetes and hypertension: a position statement by the American Diabetes Association. Diabetes Care. 2017 Sep;40(9):1273-1284. doi: 10.2337/dci17-0026.
Key words: Hypertension, Diabetes, Guidelines, American Diabetes Association

6. Kim SM, Zhao D, Schneider ALC, Korada SK, Lutsey PL, Guallar E, Alonso A, Windham BG, Gottesman RF, Michos ED. Association of parathyroid hormone with 20-year cognitive decline: The ARIC study. Neurology. 2017 Aug 29;89(9):918-926.
Key words: Parathyroid hormone, cognitive decline, risk factors

7. Korada SKC, Zhao D, Tibuakuu M, Brown TT, Jacobson LP, Guallar E, Bolan RK, Palella FJ, Margolick JB, Martinson JJ, Budoff MJ, Post WS, Michos ED. Frailty and subclinical coronary atherosclerosis: The Multicenter AIDS Cohort Study (MACS). Atherosclerosis. 2017 Aug 26. pii: S0021-9150(17)31248-0.
Key words: Frailty, HIV disease, coronary artery atherosclerosis

8. Leng SX, Kamil J, Purdy JG, Lemmermann NA, Reddehase MJ, Goodrum FD. Recent advances in CMV tropism, latency, and diagnosis during aging. Geroscience. 2017 Jun;39(3):251-259. doi: 10.1007/s11357-017-9985-7. Epub 2017 Jul 5.
Key words: Aging; CMV tropism; Diagnosis; Latency

9. Levine GN, Lange RA, Bairey-Merz CN, Davidson RJ, Jamerson K, Mehta PK, Michos ED, Norris K, Ray IB, Saban KL, Shah T, Stein R, Smith SC Jr; American Heart Association Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nursing; and Council on Hypertension. Meditation and Cardiovascular Risk Reduction: A Scientific Statement from the American Heart Association. J Am Heart Assoc. 2017 Sep 28;6(10). pii: e002218. doi: 10.1161/JAHA.117.002218.
Key words: Meditation, Cardiovascular Risk, Position Statement, American Heart Association

10. Lonze BE, Dagher NN, Alachkar N, Jackson AM, Montgomery RA. Non-traditional sites for vascular Anastomoses to Enable Kidney Transplantation in Patients with Major Systemic Venous Thromboses. Clin Transplant. 2017 Sep 28. doi: 10.1111/ctr.13127. [Epub ahead of print]
Key words: kidney transplantation; living donor; surgical technique; vasculopathy

11. Love CL. Lead reliability: How can we do better? Heart Rhythm 2017; 14(10):1547.
Key words: cardiac pacing, lead failure, lead reliability
No PMID available

12. Ratchford EV, Martin SS. Statins. Vasc Med. 2017 Aug 1:1358863X17722212. doi: 10.1177/1358863X17722212. [Epub ahead of print]
Key words: statins
PMID: 28803537

13. Wilkoff BL, Kennergren C, Love CJ, Kutalek SP, Epstein LM, Carrillo R. Bridge to surgery: Best practice protocol derived from early clinical experience with the Bridge Occlusion balloon. Federated Agreement from the Eleventh Annual Lead Management Symposium. Heart Rhythm 2017; October 14(10):1574-1578.
Key words: lead extraction, SVC tear, cardiac pacing
PMID: 28716703

1. Sinha SK, Chrispin J, Barth A, Rickard JJ, Spragg DD, Berger R, Calkins H, Tomaselli G, Marine JE.
Clinical recognition of pacemaker battery depletion and automatic reprogramming.
Pacing Clin Electrophysiol. 2017 Jun 15. doi: 10.1111/pace.13135. [Epub ahead of print] Review.
Key words: Atrioventricular nodal re-entrant tachycardia; Catheter ablation; Complications ; Dual AV nodal physiology; Long-term success


1. Atre S. Modelling approaches for tuberculosis: are they realistic? Lancet Global Health. 2017 Mar;5(3):e268. doi: 10.1016/S2214-109X(17)30048-7.
Key words: tuberculosis, disease modeling

2. Blumenthal RS, Gluckman TJ, Martin SS. Trends in the use of moderate-intensity to high-intensity statin and nonstatin lipid-lowering therapy: Turning off the faucet is much more valuable than mopping up the floor. JAMA Cardiol. 2017 Mar 1. doi: 10.1001/jamacardio.2016.6007. [Epub ahead of print]
Key words: statins, lipids, prevention
PMID: 28249079

3. Houp JA, Schillinger KP, Eckstein AJ, Vega RM, Desai NM, Lonze BE, Jackson AM. Casting a smaller net into a bigger donor pool: A single center's experience with the new kidney allocation system.
Key words: Calculated Panel Reactive Antibody (CPRA); HLA sensitization; Kidney allocation system (KAS); Kidney transplantation; Unacceptable antigens
Hum Immunol. 2017 Jan;78(1):49-53.

4. McCurdy SR, Kasamon YL, Kanakry CG, Bolaños-Meade J, Tsai HL, Showel MM, Kanakry JA, Symons HJ, Gojo I, Smith BD, Bettinotti MP, Matsui WH, Dezern AE, Huff CA, Borrello I, Pratz KW, Gladstone DE, Swinnen LJ, Brodsky RA, Levis MJ, Ambinder RF, Fuchs EJ, Rosner GL, Jones RJ, Luznik L.
Comparable composite endpoints after HLA-matched and HLA-haploidentical transplantation with post-transplantation cyclophosphamide. Haematologica. 2017 Feb;102(2):391-400

5. McDonald OG, Li X, Saunders T, Tryggvadottir R, Mentch SJ, Warmoes MO, Word AE, Carrer A, Salz TH, Natsume S, Stauffer KM, Makohon-Moore A, Zhong Y, Wu H, Wellen KE, Locasale JW, Iacobuzio-Donahue CA, Feinberg AP. Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis. Nat Genet. 2017 Mar;49(3):367-376. doi: 10.1038/ng.3753.

6. Page KR, Polk S. Chilling effect? Post-election health care use by undocumented and mixed-status families. NEJM. 2017 Mar 8. doi: 10.1056/NEJMp1700829.
Key words: Affordable Care Act, immigrant Latinos, immigration, undocumented immigrants, health care access

7. Philogene MC, Bagnasco S, Kraus ES, Montgomery RA, Dragun D, Leffell MS, Zachary AA, Jackson AM.
Anti-angiotensin II type 1 receptor and anti-endothelial cell antibodies: a cross-sectional analysis of pathological findings in allograft biopsies. Transplantation. 2017 Mar;101(3):608-615.

8. Plante TB, Martin SS. Wearable technology and long-term weight loss. JAMA. Jan 17;317(3):318-319.
Key words: digital health, mobile health, obesity
PMID: 28114543

9. Sathiyakumar V, Blumenthal RS, Nasir K, Martin SS. Addressing knowledge gaps in the 2013 ACC/AHA guideline on the assessment of cardiovascular risk: A review of recent coronary artery calcium literature.
Curr Atheroscler Rep. 2017 Feb;19(2):7. doi: 10.1007/s11883-017-0643-4.
Key words: cardiovascular disease, coronary artery calcium, cost-effectiveness
PMID: 28130653

1. Ashikaga H, James RG. Hidden structures of information transport underlying spiral wave dynamics. Chaos. 2017 Jan;27(1):013106.
Key words: Spiral waves; Information theory; Lagrangian mechanics; Pattern formation; Time series analysis
PMID: 28147497

2. Downs JA, Mathad JS, Reif LK, McNairy ML, Celum C, Boutin-Foster C, Deschamps MM, Gupta A, Hokororo A, Katz IT, Konopasek L, Nelson R, Riviere C, Glimcher LH, Fitzgerald DW. The ripple effect: why promoting female leadership in global health matters. Public Health Action. 21 Dec 2016;6(4):210-211(2).
Key words: academic faculty; female; global health; leadership; research
PMID: 28123954

3. Evans NS, Ratchford EV. The swollen leg. Vasc Med. 2016 Dec;21(6):562-564.
Key words: deep vein thrombosis; edema; lymphedema; venous insufficiency
PMID: 27738281

4. Metkus TS, Albaeni A, Chandra-Strobos N, Eid SM. Incidence and prognostic impact of respiratory support in patients with ST-segment elevation myocardial infarction. Am J Cardiol. 2017;119(2):171-177.
Key words: STEMI, mechanical ventilation, respiratory failure, acute coronary syndrome

5. Metkus TS, Tampakakis E, Mullin CJ, Houston BA, Kolb TM, Mathai SC, Damico R, Maron BA, Hassoun PM, Brower RG, Tedford RJ. Pulmonary arterial compliance in acute respiratory distress syndrome: clinical determinants and association with outcome from the fluid and catheter treatment trial cohort. Crit Care Med. 2017 Mar;45(3):422-429.
Key words: acute respiratory distress syndrome, pulmonary vascular, pulmonary hypertension

6. Zhao D, Ouyang P, de Boer IH, Lutsey PL, Farag YM, Guallar E, Siscovick DS, Post WS, Kalyani RR, Billups KL, Michos ED. Serum vitamin D and sex hormones levels in men and women: The Multi-Ethnic Study of Atherosclerosis (MESA). Maturitas. 2017 Feb;96:95-102. doi: 10.1016/j.maturitas.2016.11.017.
Key words: Vitamin D, sex hormones, testosterone, estradiol, sex hormone binding globulin

1. Berkowitz S, Brown P, Brotman D, Deutschendorf A, Dunbar L, Everett A, Hickman D, Howell E, Purnell L, Sylvester C, Zollinger R, Bellantoni M, Durso S, Lyketsos C, Rothman P on behalf of the J-CHiP program. Johns Hopkins Community Health Partnership: A Model for Transformation. Healthcare: The Journal of Delivery Science and Innovation. 2016 Sep 29. pii: S2213-0764(16)30024-0.
Key words: Health Care Transformation, Quality of Care, Cost of Care, Accountable Care,
Care Coordination, Population Health

PMID: 27693204

2. Collins R, Reith C, Emberson J, Armitage J, Baigent C, Blackwell L, Blumenthal R, Danesh J, Smith GD, DeMets D, Evans S, Law M, MacMahon S, Martin S, Neal B, Poulter N, Preiss D, Ridker P, Roberts I, Rodgers A, Sandercock P, Schulz K, Sever P, Simes J, Smeeth L, Wald N, Yusuf S, Peto R. Interpretation of the evidence for the efficacy and safety of statin therapy. Lancet. 2016 Sep 8. pii: S0140-6736(16)31357-5. doi: 10.1016/S0140-6736(16)31357-5. [Epub ahead of print]
Key words: Statins; Cardiovascular Disease; Evidence

3. Evans NS, Ratchford EV. The swollen leg. Vasc Med. 2016 Dec;21(6):562-564.
Key words: deep vein thrombosis; edema; lymphedema; venous insufficiency
PMID: 27738281

4. Gilotra NA, Shpigel A, Okwuosa IS, Tamrat R, Flowers D, Russell SD. Patients commonly believe their heart failure hospitalizations are preventable and identify worsening heart failure, nonadherence, and a knowledge gap as reasons for admission. J Card Fail. 2016 Oct 11. pii: S1071-9164(16)31163-0. [Epub ahead of print]
Key words: heart failure, readmissions

5. Gilotra NA, Bennett MK, Shpigel A, Ahmed HM, Rao S, Dunn JM, Harrington C, Freitag TB, Halushka MK, Russell SD. Outcomes and predictors of recovery in acute-onset cardiomyopathy: A single-center experience of patients undergoing endomyocardial biopsy for new heart failure. Am Heart J. 2016 Sep;179:116-26.
Key words: myocarditis, recent onset cardiomyopathy, heart biopsy

6. Gulick RM, Wilkin TJ, Chen YQ, Landovitz RJ, Amico KR, Young AM, Richardson P, Marzinke MA, Hendrix CW, Eshleman SH, McGowan I, Cottle LM, Andrade A, Marcus C, Klingman KL, Chege W, Rinehart AR, Rooney JF, Andrew P, Salata RA, Magnus M, Farley JE, Liu A, Frank I, Ho K, Santana J, Stekler JD, McCauley M, Mayer KH. Phase 2 study of the safety and tolerability of maraviroc-containing regimes to prevent HIV infection in men who have sex with men (MSM) (HPTN 069/ACTG A5305). J Infect Dis. 2016 Nov 2. pii: jiw525. [Epub ahead of print]
Key words: maraviroc, HIV infection

7. Marsteller JA, Young JH, Fakeye OA, Hsu Y, McGuire M, Poffenroth MG, Berkowitz SA. Early provider perspectives within an accountable care organization. The American Journal of Accountable Care. 2016 Sept 14. 27-37.
Key words: Accountable Care Organization, Academic Medical Center, Provider Engagement, Population Health, Care Coordination
No PMID available

8. Miller PE, Zhao D, Frazier-Wood AC, Michos ED, Averill M, Sandfort V, Burke GL, Polak JF, Lima JA, Post WS, Blumenthal RS, Guallar E, Martin SS. Associations between coffee, tea, and caffeine intake with coronary artery calcification and cardiovascular events. Am J Med. 2016 Sep 15. pii: S0002-9343(16)30925-1. doi: 10.1016/j.amjmed.2016.08.038. [Epub ahead of print]
Key words: Caffeine; Cardiovascular events; Coffee; Coronary artery calcium; Tea

9. Sinha SK, Crain B, Flickinger K, Calkins H, Rickard J, Cheng A, Berger R, Tomaselli G, Marine JE. Cardiovascular implantable electronic device function and longevity at autopsy: an underestimated resource. Heart Rhythm. 2016 Oct; 13(10): 1971 - 1976.
PMID: 27634115

10. Sinha SK, Crain B, Flickinger K, Calkins H, Rickard J, Cheng A, Berger R, Tomaselli G, Marine JE. Clinical inferences of cardiovascular implantable electronic device analysis at autopsy. Journal of the American College of Cardiology. 2016 Sept 20; 68(12): 1255-1264.
PMID: 27241351

1. Anderson JJB, Kruszka B, Delaney JAC, He K, Burke GL, Alonso A, Bild DE, Budoff MJ, Michos ED. Calcium intake and the risk of coronary arterial calcification and its progression among older adults: 10-year follow-up of the Multi-Ethnic Study of Atherosclerosis (MESA). J Am Heart Assoc. 2016 Oct 11;5(10). pii: e003815.
Key words: Calcium, supplements, diet, coronary calcium scores, cardiovascular risk
PMID: 27729333

2. Gupte N, Kinikar A, McIntire KN, Bhosale R, Patil S, Suryavanshi N, et al. Efficacy of six-week extended-dose nevirapine varies by infant birth weight with greatest relative efficacy in low birth weight infants. PLoS ONE. 11(9):e0162979. doi:10.1371/journal.pone.0162979.
Key words: SWEN, HIV, LBW infants, ART, HIV
PMID: 27689883

3. Lutsey PL, Parrinello CM, Misialek JR, Hoofnagle AN, Henderson CM, Laha TJ, Michos ED, Eckfeldt JH, Selvin E. Short-term variability of vitamin D-related biomarkers. Clin Chem. 2016 Sep 30. pii: clinchem.2016.261461. [Epub ahead of print]
Key words: Vitamin D, parathyroid hormone, calcium, phosphate, laboratory variability

4. Orbai AM, de Wit M, Mease P, et al. International patient and physician consensus on a psoriatic arthritis core outcome set for clinical trials. Ann Rheum Dis. 2016 Sep 9. pii: annrheumdis-2016-210242. doi: 10.1136/annrheumdis-2016-210242. [Epub ahead of print]
Key words: Outcomes research, Psoriatic Arthritis, Qualitative research, Spondyloarthritis

5. Yalcin H, Valenta I, Yalcin F, Ra J, Vasquez N, Kucukler N, Tahari A, Corona-Villalobos C, Pozios I, Zhou Y, Pomper M, Abraham TP, Schindler TH, Abraham MR. Diffuse subendocardial hypoperfusion leads to transient left ventricular cavity dilation by 13N-ammonia perfusion PET in hypertrophic cardiomyopathy patients. Am J Cardiol. 2016 Sep 15. pii: S0002-9149(16)31501-6. doi: 10.1016/j.amjcard.2016.08.085. [Epub ahead of print]
Key words: subendocardial hypoperfusion, left ventricular cavity dilation, 13N-ammonia, PET, hypertrophic cardiomyopathy

1. Bettinotti MP, Zachary AA, Leffell MS. Clinically relevant interpretation of solid phase assays for HLA antibody. Curr Opin Organ Transplant. 2016 Aug;21(4):453-8.
Key words: antibody-mediated rejection, HLA epitopes, HLA-specific antibodies, solid phase immunoassays

2. Florido R, Zhao D, Ndumele CE, Lutsey PL, McEvoy JW, Windham BG, Pankow JS, Guallar E, Michos ED. Physical Activity, Parental History of Premature Coronary Heart Disease, and Incident Atherosclerotic Cardiovascular Disease in the Atherosclerosis Risk in Communities (ARIC) Study. J Am Heart Assoc. 2016 Aug 30;5(9). pii: e003505. doi: 10.1161/JAHA.116.003505.
Key words: Physical activity, family history, atherosclerotic cardiovascular disease

1. Alonso A, Misialek JR, Michos ED, Eckfeldt J, Selvin E, Soliman EZ, Chen LY, Gross MD, Lutsey PL. Serum 25-hydroxyvitamin D and the incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study. Europace. 2016 Aug;18(8):1143-9. doi: 10.1093/europace/euv395.
Key words: vitamin D, atrial fibrillation, cohort study

2. Chida NM, Ghanem KG, Auwaerter PG, Wright SM, Melia MT. Defining clinical excellence in adult infectious disease practice. Open Forum Infect Dis. 2016 Jun 16;3(3):ofw122. doi: 10.1093/ofid/ofw122. eCollection 2016. PMID: 27419186; PMCID: PMC4942759.
Key words: clinical excellence; clinician; infectious disease

3. Farag YM, Guallar E, Zhao D, Kalyani RR, Blaha MJ, Feldman DI, Martin SS, Lutsey PL, Billups KL, Michos ED. Vitamin D deficiency is independently associated with greater prevalence of erectile dysfunction: The National Health and Nutrition Examination Survey (NHANES) 2001-2004. Atherosclerosis. 2016 Jul 29;252:61-67. doi: 10.1016/j.atherosclerosis.2016.07.921. [Epub ahead of print]
Key words: Vitamin D, erectile dysfunction, cardiovascular risk, race/ethnicity

4. Gilotra NA, Minkove N, Bennett M, Tedford RJ, Steenbergen C, Judge DP, Halushka MK, Russell SD. Lack of relationship between serum cardiac troponin i level and giant cell myocarditis diagnosis and outcomes. J Card Fail. 2016 Jul;22(7):583-5.
Key words: cardiac biomarkers, cardiomyopathy, endomyocardial biopsy, myocarditis

5. Grimm JC, Sciortino CM, Magruder JT, Dungan SP, Valero V III, Sharma K, Tedford RJ, Russell SD, Whitman GJ, Silvestry SC, Shah AS. Outcomes in patients bridged with univentricular and biventricular devices in the modern era of heart transplantation. Ann Thorac Surg. 2016 Jul;102(1):102-8.
Key words: LVAD, mechanical circulatory support, heart transplantation, outcomes, BiVADs

6. Houston BA, Kalathiya RJ, Hsu S, Loungani R, Davis ME, Coffin ST, Haglund N, Maltais S, Keebler ME, Leary PJ, Judge DP, Stevens GR, Rickard J, Sciortino CM, Whitman GJ, Shah AS, Russell SD, Tedford RJ. Right ventricular afterload sensitivity dramatically increases after left ventricular assist device implantation: a multi-center hemodynamic analysis. J Heart Lung Transpl. 2016 Jul;35(7):868-76.
Key words: right ventricle, LVAD, mechanical circulatory support, afterload

7. Hsu S, Houston BA, Tampakakis E, Bacher AC, Rhodes PS, Mathai SC, Damico RK, Kolb TM, Hummers LK, Shah AA, McMahan Z, Corona-Villalobos CP, Zimmerman SL, Wigley FM, Hassoun PM, Kass DA, Tedford RJ. Right ventricular functional reserve in pulmonary arterial hypertension. Circulation. 2016 Jun 14;133(24):2413-22.
Key words: right ventricle, reserve, pulmonary arterial hypertension, systemic sclerosis

8. Mave V, Chandanwale A, Kinikar A, Khadse S, Kagal A, Gupte N, Suryavanshi N, Nimkar S, Koli H, Khwaja S, Bharadwaj R, Joshi S, Horng H, Benet LZ, Ramachandran G, Dooley KE, Gupta A, Gandhi M. Isoniazid hair concentrations in children with tuberculosis: a proof of concept study. International Journal of Tuberculosis and Lung Disease. 2016 Jun;20(6):844-7. PMCID: PMC4889729.
Key words: hair assays; isoniazid drug concentrations; paediatric TB; therapeutic drug monitoring; tuberculosis
PMID: 27155191

9. Michos ED, Blaha MJ. Encouraging young women to move more: linking physical activity in young adulthood to coronary risk in women. Circulation. 2016 Jul 26;134(4):300-3. doi: 10.1161/CIRCULATIONAHA.116.023400.
Key words: Physical activity, women, coronary heart disease, editorial

10. Mukherjee M, Chung SE, Ton VK, Tedford RJ, Hummers LK, Wigley FM, Abraham TP, Shah AA. unique abnormalities in right ventricular longitudinal strain in systemic sclerosis patients. Circulation: Cardiovascular Imaging. 2016 Jun;9(6).
Key words: right ventricle, systemic sclerosis, strain, echocardiography, pulmonary hypertension

11. Rizzardi LF, Kunz H, Rubins K, Chouker A, Quiriarte H, Sams C, Crucian BE, Feinberg AP. Evaluation of techniques for performing cellular isolation and preservation during microgravity conditions. NPJ Microgravity. 2016; 2, 16025. doi:10.1038/npjmgrav.2016.25
Key words: space travel, microgravity, molecular methods

12. Rooney MR, Pankow JS, Sibley SD, Selvin E, Reis JP, Michos ED, Lutsey PL. Serum calcium and incident type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) study. Am J Clin Nutr. 2016 Aug 10. pii: ajcn130021. [Epub ahead of print]
Key words: serum calcium, diabetes, race/ethnicity, cohort study

13. Williams MS, Ngongang CK, Ouyang P, Betoudji F, Harrer C, Wang NY, Ziegelstein RC. Gender differences in platelet brain derived neurotrophic factor in patients with cardiovascular disease and depression. J Psychiatr Res. 2016 Jul;78:72-7.
Key words: BDNF; Platelets; Gender; CAD; Depression

1. Bennet CS, Dahagam CR, Virani SS, Martin SS, Blumenthal RS, Michos ED, McEvoy JW. Lipid management guidelines from the Departments of Veteran Affairs and Defense: a critique. Am J Med. 2016 May 3. pii: S0002-9343(16)30450-8. doi: 10.1016/j.amjmed.2016.04.012. [Epub ahead of print]
Key words: atherosclerotic cardiovascular disease; coronary artery calcium; dyslipidemia; guidelines; veterans affairs

2. Bettinotti MP, Zachary AA, Leffell MS. Clinically relevant interpretation of solid phase assays for HLA antibody. Curr Opin Organ Transplant. 2016 May 19. [Epub ahead of print]
Key words: antibody-mediated rejection, HLA epitopes, HLA-specific antibodies, solid phase immunoassays

3. Kambhampati S, Ashvetiya T, Stone NJ, Blumenthal RS, Martin SS. Shared decision-making and patient empowerment in preventive cardiology. Curr Cardiol Rep. 2016 May;18(5):49.
Key words: atherosclerotic cardiovascular disease; cardiovascular prevention; patient empowerment; preventive cardiology; shared decision-making

4. Lupton JR, Quispe R, Kulkarni K, Martin SS, Jones SR. Serum homocysteine is not independently associated with an atherogenic lipid profile: The Very Large Database of Lipids (VLDL-21) study. Atherosclerosis. 2016 Jun;249:59-64.
Key words: atherosclerosis; glycemic status; homocysteine; kidney function; lipid; lipoprotein

5. Martin SS, Hasan RK. Bioresorbable vascular scaffolds in coronary artery disease: weighing the evidence and next steps. Ann Intern Med. 2016 Jun 7;164(11):775-6.
Key words: stents; bioresorbable; coronary artery disease

6. Mave V, Chandanwale A, Kinikar A, Khadse S, Kagal A, Gupte N, Suryavanshi N, Nimkar S, Koli H, Khwaja S, Bharadwaj R, Joshi S, Horng H, Benet LZ, Ramachandran G, Dooley KE, Gupta A, Gandhi M. Isoniazid hair concentrations in children with tuberculosis: a proof of concept study. Int J Tuberc Lung Dis. 2016 Jun;20(6):844-7. doi: 10.5588/ijtld.15.0882
Key words: tuberculosis, pediatric TB, TB therapy, INH

7. Mukherjee M, Chung SE, Ton VK, Tedford RJ, Hummers LK, Wigley FM, Abraham TP, Shah AA. Unique abnormalities in right ventricular longitudinal strain in systemic sclerosis patients. Circ Cardiovasc Imaging. 2016 Jun;9(6). pii: e003792.
Key words: cardiomyopathies; heart ventricles; hypertension, pulmonary; scleroderma, systemic; ventricular function, right

8. Patel J, Martin SS, Banach M. Expert opinion: the therapeutic challenges faced by statin intolerance. Expert Opin Pharmacother. 2016 Jun 2. [Epub ahead of print]
Key words: cardiovascular; intolerance; myopathy; prevention; statin

9. Philogene MC, Bagnasco S, Kraus ES, Montgomery RA, Dragun D, Leffell MS, Zachary AA, Jackson AM. Anti-angiotensin II type 1 receptor and anti-endothelial cell antibodies: a cross-sectional analysis of pathological findings in allograft biopsies. Transplantation. 2016 May 24. [Epub ahead of print]
Key words: anti-angiotensin II type 1, anti-endothelial cell, antibodies, allograft biopsy

10. Philogene MC, Jackson AM, Non-HLA antibodies in transplantation: when do they matter? Curr Opin Organ Transplant. 2016 Jun 1. [Epub ahead of print]
Key words: allograft rejection, antibody-mediated rejection, non-HLA antibody, transplantation

11. Shah M, Hanrahan C, Wang Z, Dendukuri N, Lawn SD, Denkinger CM, Steingart KR. Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in HIV-positive adults. Cochrane Database Syst Rev. 2016 May 10;5:CD011420. doi: 10.1002/14651858.CD011420.pub2.
Key words: tuberculosis, HIV, HIV-associated TB, TB testing, TB diagnosis, LF-LAM

1. Cooper M, Hicks C, Ratchford EV, Salameh MJ, Malas M. Diagnosis and treatment of uncomplicated type B aortic dissection. Vasc Med. 2016 Apr 28.
Key words: TEVAR; aorta; aortic diseases; best medical therapy; type B aortic dissection

2. DeMazumder D, Limpitikul WB, Dorante M, Dey S, Mukhopadhyay B, Zhang Y, Moorman JR, Cheng A, Berger RD, Guallar E, Jones SR, Tomaselli GF. Entropy of cardiac repolarization predicts ventricular arrhythmias and mortality in patients receiving an implantable cardioverter-defibrillator for primary prevention of sudden death. Europace. 2016 Apr 4. pii: euv399.
Key words: Chaos theory; Heart failure; Heart rate variability; Non-linear dynamics; QT variability; Risk prediction; Sudden cardiac death

3. Handy CE, Desai CS, Dardari ZA, Al-Mallah MH, Miedema MD, Ouyang P, Budoff MJ, Blumenthal RS, Nasir K, Blaha MJ. The association of coronary artery calcium with noncardiovascular disease: The Multi-Ethnic Study of Atherosclerosis. JACC Cardiovasc Imaging. 2016 Mar 3. pii: S1936-878X(16)00043-7. doi: 10.1016/j.jcmg.2015.09.020. [Epub ahead of print]
Key words: aging, cancer, coronary artery calcium, coronary artery disease

4. Khazai B, Golden SH, Colangelo LA, Swerdloff R, Wang C, Honoris L, Gapstur SM, Ouyang P, Cushman M, Li D, Kopp P, Vaidya D, Liu K, Dobs A, Budoff M. Association of endogenous testosterone with subclinical atherosclerosis in men: the multi-ethnic study of atherosclerosis. Clin Endocrinol (Oxf). 2016 May;84(5):700-707. doi: 10.1111/cen.12997. Epub 2016 Feb 2.
Key words: testosterone, sex hormones, coronary artery calcium, carotid intimal-medial thickness, atherosclerosis

5. Limpitikul WB, Limphong P, Dick IE, Hyun Choi M, Yang W, Babich J, Tester DJ, Ackerman MJ, Tomaselli GF, Yue DT. Functional rescue of calmodulinopathy IPSC-derived cardiomyocytes -- a foray into personalized medicine. Biophysical J. 2016; 110 (3):439a 02.
Key words: cardiac arrhythmia, cardiomyocytes, biophysical

6. Ouyang P, Wenger NK, Taylor D, Rich-Edwards JW, Steiner M, Shaw LJ, Berga SL, Miller VM, Merz NB. Strategies and methods to study female-specific cardiovascular health and disease: a guide for clinical scientists. Biol Sex Differ. 2016 Mar 31;7:19. doi: 10.1186/s13293-016-0073-y. eCollection 2016.
Key words: cardiovascular disease, sex specific, women

7. Salameh MJ, Ratchford EV. Aortic dissection. Vasc Med. 2016 Mar 17. pii: 1358863X16632898.
Key words: aortic dissection

8. Santa-Maria CA, Blackford A, Nguyen AT, Skaar TC, Philips S, Oesterreich S,Rae JM, Desta Z, Robarge J, Henry NL, Storniolo AM, Hayes DF, Blumenthal RS, Ouyang P, Post WS, Flockhart DA, Stearns V; Consortium on Breast Cancer Pharmacogenomics (COBRA). Association of variants in candidate genes with lipid profiles in women with early breast cancer on adjuvant aromatase inhibitor therapy. Clin Cancer Res. 2016 Mar 15;22(6):1395-402. doi: 10.1158/1078-0432.CCR-15-1213.
Key words: Lipid profile, genotype, breast cancer, women, aromatase inhibitor therapy

9. Shah RV, Murthy VL, Allison MA, Ding J, Budoff M, Frazier-Wood AC, Lima JA, Steffen L, Siscovick D, Tucker KL, Ouyang P, Abbasi SA, Danielson K, Jerosch-Herold M, Mozaffarian D. Diet and adipose tissue distributions: The Multi-Ethnic Study of Atherosclerosis. Nutr Metab Cardiovasc Dis. 2016 Mar;26(3):185-93. doi: 10.1016/j.numecd.2015.12.012.
Key words: adiposity, body mass index, diet, inflammation, obesity

1. Basavaraj A, Chandanwale A, Patil A, Kadam D, Joshi S, Gupte N, McIntire K, Jain D, Dalal H, Badave R, DeLuca A, Gupta A, Bollinger R, Mave V. High tuberculosis risk among medical trainees, Pune, India. Emerg Infect Dis. 2016 Mar;22(3). doi: 10.3201/eid2203.151673.PMID: 26889712.
Key words: India; TB; healthcare workers; medical trainees; occupational diseases; respiratory infections; tuberculosis and other mycobacteria

2. Gupta A, Chandrasekaran P, Mave V, Kadam D, Suryavanshi N, Shivakumar SV, Kohli R, Gupte N, Thiruvengadam K, Kagal A, Meshram S, Bharadwaj R, Khadse S, Ramachandran G, Hanna L, Pradhan N, Gomathy NS, DeLuca A, Gupta A, Swaminathan S. Cohort for tuberculosis research by the Indo-US medical partnership (CTRIUMPH): a multi-centric prospective observational study. BMJ Open. 2016 Feb 25;6(2):e010542. doi: 10.1136/bmjopen-2015-010542.
Key words: Epidemiology, tuberculosis

3. Gupta A, Mathad JS, Abdel-Rahman SM, Albano JD, Botgros R, Brown V, Browning RS, Dawson L, Dooley KE, Gnanashanmugam D, Grinsztejn B, Hernandez-Diaz S, Jean-Philippe P, Kim P, Drapkin Lyerly A, Mirochnick M , Mofenson LM4, Montepiedra G, Piper G, Sahin L, Savic R, Smith B, Spiegel H, Swaminathan S, Watts DH, White A. Towards earlier inclusion of pregnant and postpartum women in TB drug trials: Consensus statements from an International Expert Panel. Clin Infect Dis. 2016 Mar 15;62(6):761-9. doi: 10.1093/cid/civ991. Epub 2015 Dec 9.
Key words: MDR tuberculosis; clinical trials; latent tuberculosis infection; pregnancy; tuberculosis

4. Gupta A, Montepiedra G, Gupte A, Jubulis J, Zeldow B, Detrick B, Violari A, Madhi SA, Bobat R, Cotton MF, Mitchell C, Spector SA, for the IMPAACT NWCS113 and P1041 Study Team. Low vitamin-D levels combined with PKP3-SIGIRR-TMEM16J host variants is strongly associated with tuberculosis and death in HIV-infected and -exposed infants. PLOS ONE. 2016 Feb 12;11(2):e0148649. doi: 10.1371/journal.pone.0148649. eCollection 2016.

5. Hosseinipour MC, Bisson GP, Miyahara S, Sun X, Moses A. Riviere C, Kirui FK, Badal-Faesen S, Lagat D, Nyirenda M, Naidoo K, Hakim11 J, Mugyenyi P, Henostroza G, Leger PD, Lama JR, Mohapi L, Alave J, Mave V, Veloso VG, Pillay S, Kumarasamy N, Bao J, Hogg E, Jones L, Zolopa A, Kumwenda J, Gupta A, Adult AIDS Clinical Trials Group A5274 (REMEMBER) Study Team. Empiric tuberculosis therapy versus isoniazid in advanced HIV-infected adult outpatients initiating antiretroviral therapy. Lancet. 2016 Mar 19;387(10024):1198-209.
Key words: HIV, tuberculosis, isoniazid, antiretroviral

6. Mathad J, Bhosale R, Balasubramanian U, Kanade S, Mave V, Suryavanshi N, Gupte N, Joshi S, Chandanwale A, Dupnik K, Kulkarni V, Deshpande P, Fitzgerald D, Gupta A. Quantitative IFN-?,IL-2 response and latent tuberculosis test discordance in HIV-infected pregnant women. Am J Respir Crit Care Med. 2016 Jan 14. [Epub ahead of print].
Key words: HIV; interferon gamma release assay; pregnancy; tuberculin skin test; tuberculosis

7. Mave V, Erlandson KM, Gupte N, Balgopal A, Asmuth DM, Campbell TB, Smeaton L, Kumarasamy N, Hakim J, Santos B, Riviere C, Hosseinipour MC, Sugandhavesa P, Infante R, Pillay S, Cardoso SW, Tripathy S, Mwelase N, Berendes S, Andrade BB, Thomas DL, Bollinger RC, Gupta A, and the ACTG PEARLS and NWCS 319 Study Team. Inflammation and change in body weight with antiretroviral therapy initiation in a multinational cohort of HIV-infected adults. J Infect Dis. 2016 Apr 1;213(7). doi: 10.1093/infdis/jiw096


1. Baker AM, Riekert KA, Sawicki G, Eakin MN. CF RISE: Implementing a clinic based transition program. Pediatr Allergy Immunol Pulmonol. 2015;28:250-254.
Key words: Cystic fibrosis, transition, implementation

2. Greenough WB 3rd,Ahmed M, Finucane T, Galiatsatos P, Weiss C, Bellantoni M. Where do we go from here? A small scale observation of transfer results from chronic to skilled ventilator facilities. Jrnl Crit Care. 2015 Dec;30(6):1400-2.
Key words: chronic; death; geriatrics; mortality; skilled; ventilator

3. Gupta A, Mathad JS, Abdel-Rahman SM, Albano JD, Botgros R, Brown V, Browning RS, Dawson L, Dooley KE, Gnanashanmugam D, Grinsztejn B, Hernandez-Diaz S, Jean-Philippe P, Kim P, Drapkin Lyerly A, Mirochnick M , Mofenson LM4, Montepiedra G, Piper G, Sahin L, Savic R, Smith B, Spiegel H, Swaminathan S, Watts DH, White A. Towards earlier inclusion of pregnant and postpartum women in TB drug trials: Consensus statements from an International Expert Panel. Clin Infect Dis. 2015 Dec 9. pii: civ991. [Epub ahead of print]
Key words: MDR tuberculosis; clinical trials; latent tuberculosis infection; pregnancy; tuberculosis

4. Jassal MS, Riekert KA, Borrelli B, Rand CS, Eakin MN. Cost analysis of motivational interviewing and preschool education for secondhand smoke exposure. Nicotine Tob Res. 2016: Jan 22, epub.
Key words: secondhand smoke exposure, cost analysis, motivational interviewing, children

5. Kapoor S, Gupta A, Shah M. Cost effectiveness of isoniazid preventive therapy for HIV-infected pregnant women in India. Int J Tuberc Lung Dis. 2016 Jan;20(1):85-92. doi: 10.5588/ijtld.15.0391.
Key words: IPT; economic evaluation; pregnancy; tuberculosis
PMID: 26688533

6. Mathad J, Bhosale R, Balasubramanian U, Kanade S, Mave V, Suryavanshi N, Gupte N, Joshi S, Chandanwale A, Dupnik K, Kulkarni V, Deshpande P, Fitzgerald D, Gupta A. Quantitative IFN-?,IL-2 response and latent tuberculosis test discordance in HIV-infected pregnant women. Am J Respir Crit Care Med. 2016 Jan 14. [Epub ahead of print].
Key words: HIV; interferon gamma release assay; pregnancy; tuberculin skin test; tuberculosis

7. Orandi BJ, Chow EH, Hsu A, Gupta N, Van Arendonk KJ, Garonzik-Wang JM, Montgomery JR, Wickliffe C, Lonze BE, Bagnasco SM, Alachkar N, Kraus ES, Jackson AM, Montgomery RA, Segev DL. Quantifying renal allograft loss following early antibody-mediated rejection. Am J Transplant. 2015 Feb;15(2):489-98.
Key words: clinical research; epidemiology; graft survival; health services; nephrology

8. Wright SM, Noon MJ, Greenough WB 3rd. Oral Rehydration Therapy and Feeding Replaces Total parenteral Nutrition: A Clinical Vignette. J Gen Intern Med. 2016;31(2):255-7
Key words: Ileostomy; Oral rehydration therapy; Total parenteral nutrition

1. Adesiyun T, Zhao D, Blaha MJ, Brawner CA, Keteyian SJ, Ehrman JK, Al-Mallah MH, Michos ED. Exercise parameters and risk of coronary artery disease and mortality among patients who use pulmonary medications: The FIT Project. Am J Med. 2015 Nov 30. pii: S0002-9343(15)01111-0. doi: 10.1016/j.amjmed.2015.11.013. [Epub ahead of print]
Key words: Fitness, stress testing, lung disease, mortality, coronary artery disease; heart rate; pulmonary medications

2. Bose S, Rivera-Mariani F, Chen R, Williams D, Belli A, Aloe C, McCormack MC, Breysse PN, Hansel NN. Domestic exposure to endotoxin and respiratory morbidity in former smokers with COPD. Indoor Air. 2015 Nov 7. doi: 10.1111/ina.12264. [Epub ahead of print]
Key words: COPD; Endotoxin; IL-1 ?; Indoor air; Particulate Matter; Pollution
PMID: 26547489

3. Checkley W, Foreman MG, Bhatt SP, Dransfield MT, Han M, Hanania NA, Hansel NN, Regan EA, Wise RA; COPDGene Study Investigators. Differences between absolute and predicted values of forced expiratory volumes to classify ventilatory impairment in chronic obstructive pulmonary disease. Respir Med. 2015 Nov 11. pii: S0954-6111(15)30085-8. doi: 10.1016/j.rmed.2015.11.004. [Epub ahead of print]
Key words: COPD; Reference equations; Severity criteria
PMID: 26712569

4. DeFilippis AP, Blaha MJ. Predicted vs observed clinical event risk for cardiovascular disease. JAMA. 2015;314(19):2082.
Key words: cardiovascular disease, risk

5. Gaviola C, Miele CH, Wise RA, Gilman RH, Jaganath D, Miranda JJ, Bernabe-Ortiz A, Hansel NN, Checkley W; CRONICAS Cohort Study Group. Urbanisation but not biomass fuel smoke exposure is associated with asthma prevalence in four resource-limited settings. Thorax. 2015 Dec 23. pii: thoraxjnl-2015-207584. doi: 10.1136/thoraxjnl-2015-207584. [Epub ahead of print]
Key words: Asthma; Asthma Epidemiology
PMID: 26699762

6. Hansel NN, McCormack MC, Kim V. The effects of air pollution and temperature on COPD. COPD. 2015 Dec 18:1-8. [Epub ahead of print]
Key words: COPD; heat; nitrogen dioxide; ozone; particulate matter
PMID: 26683097

7. Juraschek SP, Blaha MJ, Al-Mallah MH. Response to comment on Juraschek et al. Cardiorespiratory fitness and incident diabetes: The FIT (Henry Ford ExercIse Testing) Project. Diabetes Care 2015;38:1075-1081. Diabetes Care. 2015;38(11):e194-5.
Key words: fitness, diabetes, cardiorespiratory health

8. Kirk JA, Chakir K, Lee KH, Karst E, Holewinski RJ, Pironti G, Tunin RS, Pozios I, Abraham TP, de Tombe P, Rockman HA, Van Eyk JE, Craig R, Farazi TG, Kass DA. Pacemaker-induced transient asynchrony suppresses heart failure progression. Sci Transl Med. 2015 Dec 23;7(319):319ra207. doi: 10.1126/scitranslmed.aad2899.
Key words: Heart Failure, pacemaker, resynchronization, dyssynchrony, adrenergic, sarcomere

9. Kirk JA, Kass DA. Cellular and molecular aspects of dyssynchrony and resynchronization. Card Electrophysiol Clin. 2015 Dec;7(4):585-97. doi: 10.1016/j.ccep.2015.08.011. Review.
Key words: dyssynchrony, resynchronization

10. Martin SS, Feldman DI, Blumenthal RS, Jones SR, Post WS, McKibben RA, Michos ED, Ndumele CE, Ratchford EV, Coresh J, Blaha MJ. mActive: A randomized clinical trial of an automated mHealth intervention for physical activity promotion. J Am Heart Assoc. 2015 Nov 9;4(11). pii: e002239.
Key words: accelerometer; activity tracker; automation; cardiovascular disease; digital health; eHealth; health technology; mHealth; mobile phone; pedometer; physical activity; prevention; smartphone; text messages; texting; wearable device; wearable sensor

11. Modolo R, Figueiredo VN, Moura FA, Almeida B, Quinaglia e Silva JC, Nadruz W Jr, Lemos PA, Coelho OR, Blaha MJ, Sposito AC; Brasilia Heart Study Group. Coronary artery calcification score is an independent predictor of the no-reflow phenomenon after reperfusion therapy in acute myocardial infarction. Coron Artery Dis. 2015 November;26(7):562-6.
Key words: coronary artery calcification, reflow, reperfusion therapy, acute myocardial infarction

12. O'Neal WT, Qureshi WT, Blaha MJ, Ehrman JK, Brawner CA, Nasir K, Al-Mallah MH. Relation of risk of atrial fibrillation with systolic blood pressure response during exercise stress testing (from the Henry Ford ExercIse Testing Project). Am J Cardiol. 2015 December;116(12):1858-62.
Key words: atrial fibrillation, systolic blood pressure, exercise stress testing

13. Rice JL, Romero KM, Galvez Davila RM, Meza CT, Bilderback A, Williams DL, Breysse PN, Bose S, Checkley W, Hansel NN; GASP Study Investigators. Association between adherence to the Mediterranean diet and asthma in Peruvian children. Lung. 2015 Dec;193(6):893-9. doi: 10.1007/s00408-015-9792-9. Epub 2015 Sep 3. PubMed PMID: 26335393;
Key words: Allergic rhinitis; atopic; control; diet pattern; food frequency questionnaire; Peru

1. Berkowitz SA, Ishii L, Schulz J, Poffenroth M. Academic medical centers forming accountable care organizations and partnering with community providers: the experience of the Johns Hopkins Medicine Alliance for Patients. Acad Med. 2015 Oct 29.
Key words: Accountable care organization, Health reform, Quality of care

2. Durand D, Lewin J, Berkowitz SA. Medical imaging stewardship in the accountable care era. New Engl J Med. 2015 Oct 29;373:1691-3.
Key words: Health reform, Accountable care, Imaging, Managed care

3. Greenough WB III, Maaz A, Finucane T, Galiatsatos P, Weiss C, Bellantoni M. Where do we go from here? A small scale observation of transfer results from chronic to skilled ventilator facilities. Jrnl of Crit Care;2015 (3) 1400-02.
Key words: Ventilator, Geriatrics, Mortality, Chronic, Death

4. Martin SS, Feldman DI, Blumenthal RS, Jones SR, Post WS, McKibben RA, Michos ED, Ndumele CE, Ratchford EV, Coresh J, Blaha MJ. mActive: A randomized clinical trial of an automated mHealth intervention for physical activity promotion. J Am Heart Assoc. 2015 Nov 9;4(11). pii: e002239. doi: 10.1161/JAHA.115.002239.
Key words: Activity tracker; Cardiovascular disease; Digital health; mHealth; Physical activity; Wearable device

5. McKibben RA, Zhao D, Lutsey PL, Schneider AL, Guallar E, Mosley TH, Michos ED. Factors associated with change in 25-hydroxyvitamin D levels over longitudinal followup in the ARIC study. J Clin Endocrinol Metab. 2015 Oct 28:jc20151711. [Epub ahead of print]
Key words: Vitamin D, Longitudinal change, Factors associated with deficiency, Race

6. Urrea B, Misra S, Plante TB, Kelli HM, Misra S, Blaha MJ, Martin SS. Mobile health initiatives to improve outcomes in primary prevention of cardiovascular disease. Curr Treat Options Cardiovasc Med. 2015 Dec;17(12):59. doi: 10.1007/s11936-015-0417-7.
Key words: Cardiovascular disease; Mobile health technology; Prevention; Risk factors

1. Chan AT, Karakas MF, Vakrou S, Afzal J, Rittenbach A, Lin X, Wahl RL, Pomper MG, Steenbergen CJ, Tsui BM, Elisseeff JH, Abraham MR. Hyaluronic acid-serum hydrogels rapidly restore metabolism of encapsulated stem cells and promote engraftment. Biomaterials. 2015 Dec;73:1-11.
Key words: hyaluronic acid, hydrogels, stem cells

2. Liu K, Colangelo LA, Daviglus ML, Goff DC, Pletcher M, Schreiner PJ, Sibley CT, Burke GL, Post WS, Michos ED, Lloyd-Jones DM. Can antihypertensive treatment restore the risk of cardiovascular disease to ideal levels?: The Coronary Artery Risk Development in Young Adults (CARDIA) Study and the Multi-Ethnic Study of Atherosclerosis (MESA). J Am Heart Assoc. 2015 Sep 21;4(9).
Key words: hypertension, prevention, treatment, cardiovascular risk

3. Lupton JR, Faridi KF, Martin SS, Sharma S, Kulkarni K, Jones SR, Michos ED. Deficient serum 25-hydroxy vitamin D is associated with an atherogenic lipid profile: The Very Large Database of Lipids (VLDL-3) Study. J Clin Lipidol. 2015. In Press Accepted Manuscript. Published online: September 23 2015
Key words: Vitamin D deficiency, extended lipid panel, atherogenic lipid profile
DOI: http://dx.doi.org/10.1016/j.jacl.2015.09.006

4. Michos ED, Martin SS, Blumenthal RS. Bringing back targets to "IMPROVE" atherosclerotic cardiovascular disease outcomes: the duel for dual goals, are two targets better than one? Circulation. 2015 Sep 29;132(13):1218-20.
Key words: Cardiovascular disease, treatment goals

5. Misra S, Conte J, Resar J. Left atrial thrombus associated with interatrial septal occluder 5 years after implantation. Circ Cardiovasc Interv. 2015 Oct;8(10):e002856.
Key words: left atrial thrombus, interarterial septal occluder

6. Orandi BJ, Alachkar N, Kraus ES, Naqvi F, Lonze BE, Lees L, Van Arendonk KJ, Wickliffe C, Bagnasco SM, Zachary AA, Segev DL, Montgomery RA. Presentation and outcomes of C4d-negative antibody-mediated rejection after kidney transplantation. Am J Transplant. 2015 Aug 28. [Epub ahead of print]
Key words: C4d-negative antibody, kidney transplantation

7. Schulz J, DeCamp M, Berkowitz SA. Medicare Shared Savings Program: public reporting and shared savings distributions. Am J Manag Care. 2015 Aug;21(8):546-53.
Key words: Medicare, accountable care organization, cost savings

Return to top of Publications - Medicine Archives

Search Publications
October 2018 articles:
Trends in Clinical Research Program
Clinical Research Annual Reports
Change in JHM IRB Review Fees for Commercially-Funded Studies
Data and Safety Monitoring Board Training Manual Now Available
Good Clinical Practice (GCP) Fundamentals: Understanding and Applying GCP to Human Subject Research
Fee Schedule Adjustment for Hospital Services Charged to Clinical Trial Budgets
Change in Federalwide Assurance [FWA] Numbers
Changes to NIH-funded Human Subjects Research
Free Resources for Longitudinal Clinical Research Studies
NIH requirement for Single IRB (sIRB)
JHM IRB Reliance Requests
Sharing Partnership for Innovative Research in Translation
Johns Hopkins Institute for Clinical and Translational Research
Johns Hopkins Research Network
Visit Animal Care and Use Committee Website
Current Classes
"Interinstitutional Assurance" Agreement
Health, Safety, and Environment (HSE) presents: Safety in Research Updates
Blavatnik Awards for Young Scientists
Request for Proposals for Collaborative Research Projects - Diana Helis Henry Medical Research Foundation and Adrienne Helis Malvin Medical Research Foundation
Michael J. Fox Foundation (MJFF) Challenge
Why Project Outcomes Matter in your Interim and Final Research Performance Progress Report (RPPR)
NIH Matchmaker, A Tool For Finding Similar NIH Projects
NIH Video Tutorials on How to Apply for Grants
NIH Policy: Foreign Components Added to a Grant to a Domestic or Foreign Organization

This Month's Departmental Listings

Upcoming Deadlines for October, November and December

October Events at the Genetic Resources Core Facility


JHM AppointmentsEmployment @ JHM | Finding a Doctor | Disclaimer | Maps & Directions | Contact JHM 


                                                                                                                                                           The Web Center