Web notes  

October 2019


1. Al Ammary F, Bowring MG, Massie AB, Yu S, Waldram MM, Garonzik-Wang J, Thomas AG, Holscher CM, Qadi MA, Henderson ML, Wiseman AC, Gralla J, Brennan DC, Segev DL, Muzaale AD. The changing landscape of live kidney donation in the United States from 2005 to 2017. Am J Transplant. 2019 Sep;19(9):2614-2621. doi: 10.1111/ajt.15368.
Key words: clinical research/practice; donor nephrectomy; donors and donation: living; kidney transplantation/nephrology; kidney transplantation: living donor; registry/registry analysis

2. Alloway RR, Woodle ES, Abramowicz D, Segev DL, Castan R, Ilsley JN, Jeschke K, Somerville KT, Brennan DC. Rabbit anti-thymocyte globulin for the prevention of acute rejection in kidney transplantation. Am J Transplant. 2019 Aug;19(8):2252-2261. doi: 10.1111/ajt.15342.
Key words: autoimmunity; clinical research/practice; clinical trial; immunosuppressant - polyclonal preparations: rabbit antithymocyte globulin; immunosuppression/immune modulation; immunosuppressive regimens - induction; kidney (allograft) function/dysfunction; kidney transplantation/nephrology

3. Bowring MG, Shaffer AA, Massie AB, Cameron A, Desai N, Sulkowski M, Garonzik-Wang J, Segev DL. Center-level trends in utilization of HCV-exposed donors for HCV-uninfected kidney and liver transplant recipients in the United States. Am J Transplant. 2019 Aug;19(8):2329-2341. doi: 10.1111/ajt.15355.
Key words: Organ Procurement and Transplantation Network (OPTN); Scientific Registry for Transplant Recipients (SRTR); clinical research/practice; hepatitis C; infection and infectious agents - viral; infectious disease; kidney transplantation/nephrology; liver transplantation/hepatology

4. Chen J, Douglass J, Prasath V, Neace M, Atrchian S, Manjili MH, Shokouhi S, Habibi, M. The microbiome and breast cancer: a review. Breast Cancer Research and Treatment. 2019 Aug 27. doi: 10.1007/s10549-019-05407-5. [Epub ahead of print]
Key words: Breast cancer, Flora, Gut, Immune response, Microbiome

5. Downs B, Mercado-Rodriguez C, Cimino-Mathews A, Chen C, Yuan J, Van Den Berg EJ, Cope L, Schmitt F, Tse GM, Ali SZ, Meir-Levi D, Sood R, Li J, Richardson AL, Mosunjac M, Rizzo M, Tulac S, Kocmond K, de Guzman TN, Lai EW, Rhees B, Bates M, Wolff AC, Gabrielson E, Harvey S, Umbricht CB, Visvanathan K, Fackler MJ, Sukumar S. DNA methylation markers for breast cancer detection in the developing world. Clin Cancer Res. 2019 Jul 2. pii: clincanres.3277.2018. doi: 10.1158/1078-0432.CCR-18-3277. [Epub ahead of print]
Key words: breast cancer, early detection, methylation, markers, automation

6. Harhay MN, Ranganna K, Boyle SM, Brown AM, Bajakian T, Levin Mizrahi LB, Xiao G, Guy S, Malat G, Segev DL, Reich D, McAdams-DeMarco M. Association between weight loss before deceased donor kidney transplantation and posttransplantation outcomes. Am J Kidney Dis. 2019 Sep;74(3):361-372. doi: 10.1053/j.ajkd.2019.03.418.
Key words: Renal transplantation; deceased donor kidney transplantation (DDKT); end-stage kidney disease (ESKD); frailty; graft failure; mortality; obesity; outcomes; protein-wasting malnutrition; sarcopenia; wasting; weight loss

7. Hicks CW, Bae S, Pozo ME, DiBrito SR, Abularrage CJ, Segev DL, Garonzik-Wang J, Reifsnyder T. Practice patterns in arteriovenous fistula ligation among kidney transplant recipients in the United States Renal Data Systems. J Vasc Surg. 2019 Sep;70(3):842-852.e1. doi: 10.1016/j.jvs.2018.11.048.
Key words: AV access; Arteriovenous fistula; Ateriovenous graft; Kidney transplant; Ligation; Renal transplant

8. Jia H, Sodhi CP, Yamaguchi Y, Lu P, Ladd MR, Werts A, Fulton WB, Wang S, Prindle T Jr, Hackam DJ. Toll Like Receptor 4 Mediated Lymphocyte Imbalance Induces Nec-Induced Lung Injury. Shock. 2019 Aug;52(2):215-223. doi: 10.1097/SHK.0000000000001255.
Key words: Necrotizing Enterocolitis (NEC) , Inflammatory lung disease, Th17/Treg balance

9. Lentine KL, Koraishy FM, Sarabu N, Naik AS, Lam NN, Garg AX, Axelrod D, Zhang Z, Hess GP, Kasiske BL, Segev DL, Henderson ML, Massie AB, Holscher CM, Schnitzler MA. Associations of obesity with antidiabetic medication use after living kidney donation: An analysis of linked national registry and pharmacy fill records. Clin Transplant. 2019 Aug 17;:e13696. doi: 10.1111/ctr.13696. [Epub ahead of print]
Key words: antidiabetic medications; diabetes mellitus; health outcome; living donation; pharmacy claims; registries

10. Mogul DB, Lee J, Purnell TS, Massie AB, Ishaque T, Segev DL, Bridges JFP. Barriers to access in pediatric living-donor liver transplantation. Pediatr Transplant. 2019 Sep;23(6):e13513. doi: 10.1111/petr.13513.
Key words: access; barriers; liver; living donor; pediatric

11. Suarez-Pierre A, Crawford TC, Zhou X, Lui C, Fraser CD 3rd, Etchill E, Sharma K, Higgins RS, Whitman GJ, Kilic A, Choi CW. Impact of traumatically brain-injured donors on outcomes after heart transplantation. J Surg Res. 2019 Aug;240:40-47. doi: 10.1016/j.jss.2019.02.049.
Key words: Cardiac allograft vasculopathy; Heart transplantation; Organ allocation; Organ donation; Propensity matching; Traumatic brain injury

12. Wu AW, Weston CM, Ibe CA, Ruberman CF, Bone L, Boonyasai RT, Hwang S, Gentry J, Purnell L, Lu Y, Liang S, Rosenblum M. The Baltimore Community-Based Organizations Neighborhood Network: Enhancing Capacity Together (CONNECT) Cluster RCT. Am J Prev Med. 2019 Aug;57(2):e31-e41. doi: 10.1016/j.amepre.2019.03.013.
Key words: Community based participatory research; randomized clinical trial; hospital care; equity

13. Zuhaili B, Al-Talib K. Successful treatment of single infected calciphylaxis lesion with intralesional injection of sodium thiosulfate at high concentration. Wounds. Aug 2019; 31(8):E54-7.
Key words: calciphylaxis, end-stage renal disease, ESRD, sodium thiosulfate, infection, lesion



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October 2019 articles:
Henrietta Lacks Memorial Lecture - 10th Anniversary!
Training Opportunity: Single IRB Requirement for Cooperative Research
Research Billing Buzz eNewsletter - August 2019
Update on Insurance and Research Participant Financial Responsibility Information Sheet: Signature No Longer Required
Change in JHM IRB Review Fees for Commercially-Funded Studies
Data and Safety Monitoring Board Training Manual Now Available
Good Clinical Practice (GCP) Fundamentals: Understanding and Applying GCP to Human Subject Research
Fee Schedule Adjustment for Hospital Services Charged to Clinical Trial Budgets
Changes to NIH-funded Human Subjects Research
Free Resources for Longitudinal Clinical Research Studies
JHM IRB Reliance Requests
Sharing Partnership for Innovative Research in Translation
Johns Hopkins Institute for Clinical and Translational Research
Johns Hopkins Clinical Research Network
Visit Animal Care and Use Committee Website
Current Classes
"Interinstitutional Assurance" Agreement
Health, Safety, and Environment (HSE) presents: Safety in Research Updates
Point of Contact for NIH Loan Repayment Program
Johns Hopkins University President's Frontier Award
Michael J. Fox Foundation (MJFF) Challenge
The Gordon and Betty Moore Foundation Inventor Fellows Program
JHU SOM Update on NIH Policy on Foreign Involvement
Disclosure of Payments from Foreign Educational Institutions and Government Agencies
Institutional Letter of Support Required for Institutional Training Grant Applications
Notice to the Johns Hopkins Community Regarding the National Science Foundation Grant Reporting Requirement for Harassment Findings and Actions
Prohibited Mention of Prior Review for New Replacement Applications
NIH Policy on Foreign Component Involvement
Why Project Outcomes Matter in your Interim and Final Research Performance Progress Report (RPPR)
NIH Matchmaker, A Tool For Finding Similar NIH Projects
NIH Video Tutorials on How to Apply for Grants

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