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Open Postdoctoral Fellowship Positions at SOM-JHU

Below are current postdoctoral fellowship positions that are open at SOM-JHU. For additional details on an open position, contact the primary faculty on the listing.

  • Primary faculty: Dr. Amanda Lauer, Dr. Elisabeth Glowatski

    The Glowatzki and Lauer labs have open positions for postdoctoral fellows to investigate the mechanisms of afferent synaptic transmission in the mammalian cochlea and the role of the olivocochlear efferent system on auditory nerve fiber activity. Secondly, effects of abnormal acoustic experience on afferent and efferent activity are investigated, to gain insights into possible approaches to prevent hearing loss. Projects are ongoing in the areas of environmental sound experience and aging. 

    The Glowatzki and Lauer labs collaborate closely to implement an array of techniques to investigate peripheral and central components of the olivocochlear circuit, including electrophysiology in mouse models (evoked potentials, cellular physiology/patch clamp, optogenetic stimulation, calcium imaging), anatomy (immunohistochemistry, confocal and electron microscopy), and behavior (acoustic startle, operant conditioning, noise avoidance, etc.). We also integrate optogenetic and chemogenetic manipulations into functional studies of the olivocochlear system. The ideal candidates will have experience in one or more of these techniques and a working knowledge of the auditory system. 

    In addition to experimental techniques, postdocs will receive training in dissemination of research, grant writing, research integrity, managing collaborations, and other aspects relevant to professional development. Postdoctoral fellows receive a stipend and benefits consistent with current NIH guidelines and university policies. Applicants should have a Ph.D. or equivalent degree in neuroscience, biology, biopsychology, or related field. Initial appointment will be for one year with possible extension based on performance and availability of funding. Postdocs are part of our large and highly collaborative Center for Hearing and Balance, comprised of members from Otolaryngology-HNS, Neuroscience, Biomedical Engineering, and Psychological and Brain Science departments.

    Interested candidates should submit a CV and cover letter to Amanda Lauer alauer2@jhmi.edu and Elisabeth Glowatzki eglowat1@jhmi.edu. For more information about the labs, the center, and postdoctoral affairs at Johns Hopkins, please visit:

    www.lauerlab.com
    https://glowatzkilab.com/
    https://neuroscience.jhu.edu/research/faculty/32
    http://jhu-chb.org/ 

  • Primary faculty: Dr. Valasamo Anagnostou

    We are seeking applicants for a post-doctoral fellow position with particular focus on integrative genomics, multi-omics and liquid biopsy analyses to model tumor clonal evolution in the context of therapy. The candidate will independently carry out complex established protocols related to whole genome, exome, transcriptome, T cell receptor sequencing and circulating cell-free tumor DNA analyses, optimize bench techniques and will be involved in the analysis and interpretation of cutting-edge, high-dimensional genomic data sets generated by next generation sequencing in conjunction with transcriptomic, single-cell and liquid biopsy sequence data. Together with Dr. Anagnostou, the principal investigator, the candidate will manage, analyze, and communicate data produced in collaborative projects focused on basic and translational research in cancer biology, and is expected to lead publication efforts. Ongoing studies include, but are not limited to, mechanisms of response and resistance to immunotherapy and identification of tissue and blood-derived genomic biomarkers of response to therapies, including immunotherapy and targeted therapies.

    Duties and Responsibilities:

    • Manage their own and collaborative research projects in agreement and collaboration with the Principal Investigator
    • Identify and select best options for scientific strategies and research development based on literature reviews and collaboration with colleagues
    • Incorporate new technologies into the laboratory
    • Develop and validation of assays
    • Evaluate options regarding the purchase of new laboratory equipment
    • Contribute to writing of scientific publications and grant applications
    • Act as a resource for laboratory techniques for post-doctoral fellows, students and junior technicians
    • Identify problems and propose and implement plan for solutions


    Equipment, Machine, or Tool Requirements:
    General computer skills, with experience with Microsoft Office, independent operation of laboratory equipment such as the flow cytometer, gel electrophoresis apparatus, PCR cycler, microscopes, and laminar flow hood, data analyses skills preferred, cell culture skills preferred.

    Required Education and Experience:

    • PhD. in Science, Biotechnology or equivalent
    • Minimum of three years in a comparable laboratory performing relevant techniques preferred (can be achieved through an educational program)
    • In-depth scientific knowledge and demonstrated competency in required assays and techniques
    • Demonstrated performance to provide leadership, training, and problem-solving for junior members of the laboratory team
    • Experience in analyzing results and contributing to scientific presentations
    • Demonstrated experience in experimental design, conduct, and analysis


    Special Knowledge, Skills, or Abilities/Competencies:
    Knowledge:

    • Extracts scientific information from literature/lectures/seminars and translates into productive contributions to lab interests.


    Problem Solving Skills:

    • Identifies problem areas and proposes and implements plans for solutions.
    • Draws upon extensive experience and collaborative resources to make decisions.
    • Make decisions regarding research projects that may require assessment, revision of objectives, or altering scientific direction; considers resources and lab priorities when making decisions.
    • Exercises authority and intervenes to resolve scientific issues.


    Interpersonal Skills:

    • Provides constructive guidance to entry-level and peer lab members in a collegial manner.
    • Performs constructive self-assessment and solicits feedback from faculty and/or other lab members as appropriate.
    • Requires advanced professional and scientific communication skills.
    • Ensures PI is informed of laboratory activities as required.


    Teaming Skills:

    • Defines clear expectations for technicians and students on the project team.
    • Develops the laboratory team by interacting with, guiding, and mentoring team members.
    • Encourages and inspires goals and achievements from junior members of the scientific team.


    Innovation and Change Skills:

    • Incorporates scientific innovations regarding protocol development and research goals.
    • Proposes ideas for new projects to PI.
    • Makes changes in laboratory consistent with increasing productivity and decreasing cost.


    Contact information
    Dr. Valasamo Anagnostou
    Email:
    vanagno1@jhmi.edu

  • Primary Faculty: Dr. John Nicholas

    A postdoctoral position is available in the Viral Oncology Program of the Johns Hopkins School of Medicine Department of Oncology to undertake research on physical and functional interactions of Kaposi’s sarcoma-and primary effusion lymphoma-associated human herpesvirus 8 (HHV-8) viral interferon regulatory factors (vIRFs) with USP7 deubiquitinase and STAT transcription factors. The project will involve a variety of molecular biology, cell biology, and biophysical approaches to determine the nature and roles of the vIRF-related complexes in virus biology. A high degree of experimental independence and participation in project development are expected. Applications are invited via email to John Nicholas (nichojo@jhmi.edu)

  • Primary faculty: Dr. Jiou Wang

    Description of position
    Highly motivated postdoctoral candidates are invited to lead several new projects to address fundamental questions on protein homeostasis (Lu et al. Nature Neuroscience 2019; Liu et al. Genes & Development 2018; Periz et al. PLoS Biology 2015) and RNA homeostasis (Zhang et al. Molecular Cell 2018; Haeusler et al. Nature 2014) related to neurodegenerative diseases in the laboratory of Jiou Wang. The position is open to candidates with a wide range of backgrounds including biochemistry, molecular biology, cell biology, and structural biology on all topics of biology. Those with experience in biochemistry, molecular and cellular biology, RNA biology, and bioinformatics are particularly encouraged to apply.

    The Johns Hopkins Medical Institutions provide a stimulating and collaborative environment for biomedical research. Our lab is affiliated with Department of Biochemistry and Molecular Biology at The Bloomberg School of Public Health and Department of Neuroscience at School of Medicine. The Baltimore/Washington D.C. area also offers rich professional and living opportunities.

    A complete listing of PubMed-accessible publications can be accessed at the following URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=Jiou+Wang.

    More information available at: http://www.jhu-bmb-phd.org/faculty/jiou-wang.

    The Johns Hopkins University is an Equal Opportunity Employer.

    Instructions for applying:
    Please send a statement of research experience and career goals, a copy of Curriculum Vitae, and contact information of at least one reference to Dr. Jiou Wang at jiouw@jhmi.edu. Applications will be considered on a rolling basis until the position is filled.

  • Primary faculty: Dr. Valeria Culotta

    Description of position:
    A postdoctoral or more senior research position is available in the Culotta laboratory to study the cellular physiology of fungal pathogens. Our laboratory focuses on the role of metal nutrients and reactive oxygen species in basic fungal biology and at the host-pathogen interface during fungal infection. Successful postdoctoral candidates will be trained in bioinorganic chemistry and spectroscopy, and in the molecular and cellular biology of fungal pathogens. The Culotta lab has a strong track record for preparing postdoctoral fellows for diverse careers in academics, industry and government. The ideal postdoctoral candidate should have research experience in biochemistry with preference given for candidates with backgrounds in molecular biology and microbiology.

    Sample publications:
    Culbertson EM, Khan AA, Muchenditsi A, Lutsenko S, Sullivan DJ, Petris MJ, Cormack BP, Culotta VC. Changes in mammalian Cu homeostasis during microbial infection. Metallomics, 2020, Jan 24 DOI: 10.1039/C9MT00294D

    Robinett NG, Culbertson EM, Peterson RL, Sanchez H, Andes DR, Nett JE, Culotta VC. Exploiting the vulnerable active site of a Cu-only superoxide dismutase to disrupt fungal pathogenesis. J Biol Chem. Feb 22;294(8):2700-2713. doi: 10.1074/ 2019

    Rossi DCP, Gleason JE, Sanchez H, Schatzman SS, Culbertson EM, Johnson CJ, McNees CA, Coelho C, Nett JE, Andes DR, Cormack BP, Culotta VC. Candida albicans FRE8 encodes a member of the NADPH oxidase family that produces a burst of ROS during fungal morphogenesis PLoS Pathog. Dec 1;13(12):e1006763. doi: 10.1371/journal.ppat.1006763. 2017

    Li CX, Gleason JE, Zhang SX, Bruno VM, Cormack BP, Culotta VC. Candida albicans responds to host copper during infection by swapping metal cofactors for superoxide dismutase. Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):E5336-42.

    1. A and Culotta, VC. SOD1 integrates signals from glucose and oxygen to repress respiration. Cell. 152(1-2):224-3. 2013.

     

    Instructions for applying:
    To apply, please submit by email to vculott1@jhu.edu, a cover letter, CV, and names of three references that may be contacted. Applications will be reviewed promptly on a rolling basis until the position is filled. Johns Hopkins University is an equal opportunity employer.

  • Primary faculty: Heather Volk, PhD and Peter Zandi, PhD

    Description
    The Psychiatric Epidemiology Training (PET) program at the Johns Hopkins Bloomberg School of Public Health (JHBSPH) is housed in the Department of Mental Health. The PET is a longstanding institutional training grant currently in its 45th year of funding from the National Institute of Mental Health. As part of PET we seek to train outstanding pre-doctoral and postdoctoral candidates to lead the next generation of research studies in psychiatric epidemiology. Students and post-docs are trained to conduct leading-edge research that can inform knowledge of etiology of mental illness and associated comorbidities as well as the implementation and evaluation of mental health promotion and intervention programs across the lifespan. All supported trainees engage in regular journal clubs, seminars on psychiatric epidemiology, and work with core faculty on existing or newly developed research projects addressing the broad areas of etiology and/or intervention. The PET program is based in the Departments of Mental Health, Psychiatry, and Epidemiology, and has 4 pre-doctoral slots and 2 postdoctoral slots.

    Postdoctoral fellows participate in on-going population-based research across multiple institutions at Johns Hopkins. We particularly seek trainees with interests in the study of etiology and prevention / intervention of psychiatric disorders and related conditions. The training grant funding provides a stipend for postdoctoral fellows as well health insurance coverage and a small professional development annual allowance. Suitable postdoctoral applicants will hold a Ph.D. in Epidemiology, Biostatistics, or other quantitatively oriented population health field; or a clinical or academic doctoral degree with dedication to pursuit of psychology or psychiatry and development of methodological skills. This program is funded by the National Institute on Mental Health. Candidates must have US citizenship or permanent residence status to be eligible. Minority and women applicants are encouraged to apply.

    Postdoctoral fellows can be appointed for up to 3 years total on NIH T32 grants. The typical duration for postdocs on the PET training program is 1-2 years.

    Please contact hvolk1@jhu.edu and pzandi1@jhu.edu with any questions. Please visit the Psychiatric Epidemiology Training Program’s website:

    https://www.jhsph.edu/departments/mental-health/prospective-students-and-fellows/funding-opportunities/psychiatric-epidemiology/

    Instructions for applying:
    The PET Program is currently seeking a postdoctoral fellow for forthcoming support. We have one available postdoctoral opening beginning in the 2021-2022 academic year.  The deadline for applications for the 2021-2022 slot is March 1, 2021, and will continue on a rolling basis as needed.

    Eligible candidates should submit the following application materials via email by the deadline:

    • Curriculum Vitae (CV)
    • Statement of career objectives/research goals
    • Two (2) letters of recommendation


    To Heather Volk, PhD (hvolk1@jhu.edu) and Peter Zandi, PhD (pzandi1@jhu.edu) Psychiatric Epidemiology Training Program

  • Primary Faculty: Gene Fridman, Ph.D.

    Overall Purpose
    Miniaturize the Safe Direct Current Neural Stimulation (SDCS) system to an implantable size device and develop the electrodes for this implantable system. This is a considerable engineering challenge that requires developing a small-scale reliable microfluidic circuit that includes self-actuated microfluidic valves to control ionic current flow, function for millions of cycles, and maintain low power operation.

    Key Responsibilities:

    • Lead continuing R&D efforts of the SDCS miniaturization, reliability, and multi-channel capability.
    • Investigate the literature to apply relevant technologies to the microfluidic design.
    • Work collaboratively with others on the team focusing on electronic design and neurophysiology experiments.
    • Author manuscripts and patents associated with the innovations toward these technological developments.


    Skills and Qualifications:
    Required:

    • PhD or 5+ years experience in a relevant engineering discipline
    • Laboratory hands-on experience in designing microfluidics
    • Laboratory hands-on experience with electronic circuits


    Preferred:

    • Good chemistry background
    • Understanding of biocompatibility issues
    • Firmware programming experience


    Position Duration: Initial contract will be for 1 year, extensible for up to 4 years supported by R01 NIH grants.

    Background
    Safe Direct Current Stimulator (SDCS) technology that we are developing in our laboratory will enable creation of a new class of bioelectronic prostheses that excite, inhibit, and modulate the sensitivity of neurons. Vestibular implants, cochlear implants, and essentially all other chronically implantable neuroelectronic prostheses rely on charge-balanced, biphasic pulses or other forms of alternating current (AC) to excite neural or muscular activity without driving electrochemical reactions that would otherwise liberate toxic substances at the electrode-saline interface. All of these devices are constrained to excite the neural tissue in which they are implanted. Inhibition is difficult to achieve with these devices, because the need to avoid a net charge flow above a small threshold mandates the use of brief, charge-balanced pulses.

    Safe Direct Current Stimulation (SDCS) technology can inhibit, excite, or sensitize neurons. Conceptually, the SDCS converts alternating charge balanced-pulses delivered to two metal electrodes submerged in an electrolyte within a device to direct ionic current delivered to the tissue at the output of the device via electrolyte-gel-filled tubes positioned near the target neurons.

    Wide range of neuroengineering applications could be revolutionized with this technology: some examples are the vestibular prosthesis for balance disorders, pain suppression to control chronic neuropathic pain, asthma attack suppression, and tinnitus suppression.

    Apply by email with cv or resume to: Gene Fridman (gfridma1@jhmi.edu)
  • Primary faculty: Dr. Jennifer Kavran

    Description of position:
    A postdoctoral position is available immediately in the laboratory of Jennifer Kavran at Johns Hopkins University, Bloomberg School of Public Health, Department of Biochemistry and Molecular Biology. The laboratory is broadly interested in understanding the molecular mechanism of signal transduction. We are currently studying the mechanisms regulating the Hippo pathway and employ a combination of structural biology, biochemistry, biophysics and cell-biology approaches to understand key regulatory events in signal transduction.

    Candidates must have a PhD in biophysics, biochemistry or related discipline. We are looking for candidates who are interested in molecular mechanism, protein:protein interactions, structural biology, cell biology,and/or enzymology. Experience with in vitro biochemistry or and/or tissue culture is a plus, but not required. Candidates are expected to assist in the design, execution, and analysis of experiments, help write manuscripts for publication, and mentor junior members of the lab. Candidates are expected to work as part of a collaborative team.

    Instructions for applying:
    Interested candidates should send an email Jennifer Kavran, jkavran@jhu.edu, a (1) a cover letter including research interests, long term career goals, and accomplishments, (2) CV, and (3) contact information for three references.

  • A postdoctoral or more senior research position is available in the Culotta laboratory at the Bloomberg School of Public Health to study the cellular physiology of fungal pathogens. Our laboratory focuses on the role of metal nutrients and reactive oxygen species in basic fungal biology and at the host-pathogen interface. Successful postdoctoral candidates will be trained in the molecular and cellular biology of fungal pathogens, metalloprotein biochemistry and spectroscopy. To apply, please submit by email to vculott1@jhu.edu, a cover letter, CV, and names of references. Applications will be reviewed promptly on a rolling basis until the position is filled.

  • Co-Primary investigators: Chloe Thio, MD and Ashwin Balagopal, MD

    Description of position:
    We are seeking a highly motivated postdoctoral researcher who is interested in applying high resolution molecular techniques to liver tissue samples. The overall goal of this project is to gain insight into hepatitis B transcription at the level of the single hepatocyte before and after anti-HBV therapy. Since HBV transcription is central to HBV replication, such data are needed to advance the HBV cure field. This is a translational project that will apply high-resolution molecular techniques to tissues from HBV-infected people.

    The laboratory is based in the Department of Medicine, Division of Infectious Diseases in the Johns Hopkins University School of Medicine. One of the major goals of the group is to advance knowledge of HBV virology and immunology through translational projects that utilize clinical samples to ask critical questions. Specific projects include 1) utilizing droplet digital PCR (ddPCR) to amplify HBV DNA and RNA from single hepatocytes in people with various stages of hepatitis B and with and without treatment, 2) using RNA seq to probe biological differences between hepatocytes with and without transcriptionally silent cccDNA, 3) role of epigenetics in transcriptional silencing of cccDNA.

    Job Qualifications
    PhD in molecular biology or related field
    Experience/skills in the following areas is desired:

    • Background in hepatitis B or virology
    • Experience with standard molecular techniques, sequencing, and ideally with ddPCR
    • Strong communication and interpersonal skills
    • Fluency in written and spoken English


    Instructions for applying

    To apply please email the following to Dr. Thio (cthio@jhmi.edu) and Dr. Balagopal (abalago1@jhmi.edu)

    • Cover letter describing research interests, career goals, prior experience
    • Curriculum vitae
    • Writing sample (published paper or manuscript draft)
    • Names and contact information of 2-3 references


    Applications will be reviewed on a rolling basis starting March 29th 2021 until the position is filled

  • Primary Faculty: Luigi Adamo, MD Ph.D.

    The Adamo Lab in The Johns Hopkins University Division of Cardiology is seeking a post-doctoral fellow to lead cutting edge research in cardiac-immunology.

    We are looking for a highly motivated and independent researcher with a Ph.D. in immunology, biology, or a related field.

    Candidates must have first-author publications and proven research ability in at least one of the following areas: immunology, models of cardiac injury, cardiac physiology, lymphocyte biology, or aging. Hands-on experience in translational animal models is also required.

    Experience in the following techniques is helpful but not required: flow cytometry, immunohistochemistry, and immunofluorescence.

    A successful candidate will have a strong work ethic, strong organizational skills, excellent critical thinking abilities, excellent ability to work as part of a team and a desire to push the boundaries of existing knowledge. The postdoctoral researcher will work under supervision but will be expected to lead methods development, lead manuscript and grant writing efforts, conduct independent research and supervise junior researchers.

    We offer multifaceted scientific projects, strong scientific collaborations, and attentive mentoring in the context of the vibrant, word class research environment of Johns Hopkins University. We are passionate about discovery and drug development. If you share our passion and fit the above description, we would love to hear from you.

    Adamo Cardiac-Imunology Lab
    ladamo2@jhmi.edu
    http://hopkinsmedicine.org/adamo-lab

  • Job Title: Research Fellow
    Working Title: Research Fellow
    Job Family: Research
    FLSA: Exempt

    Department: Oncology (Cancer Epigenetics and Therapeutic Resistance)

    Reports to: Principal Investigators: Drs. Eneda Toska and Elana Fertig

    The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University is recruiting an individual to lead analyses on epigenomics analyses such as (ChIP-seq, ATAC-seq and RNA-seq) and single cell analyses in cancer models. This person will be active in the data pre-processing stages as well as analysis and interpretation of results.

    The Toska lab integrates biochemistry, cell signaling, genomics and epigenomics at bulk and single cell level to study the fundamental processes by which epigenetic regulators regulate transcription, have the ability to drive tumorigenesis and dictate therapeutic response in breast cancer. The Fertig lab develops time course models of therapeutic resistance and performs single cell technology development. Her computational methods are used to determine the molecular mechanisms of therapeutic resistance from multi-platform genomics and epigenomics data. The successful candidate will become a fundamental component of this multidisciplinary team with mentorship in both computational and biological processes affecting therapeutic response in cancer.

    Eligible candidate will be involved in designing and developing analysis plans to address biological hypotheses in our ChIP-seq/ATAC-seq/RNA-seq and RNA-seq and ATAC-seq at the single level acquired from breast cancer models such as cell lines, organoids, and patients treated with targeted therapies. The candidate will interact daily with other data analysts within the Institute, as well as Genomics experts, and clinicians. This position requires collaboration with clinical and scientific investigators in research/study design, data analysis plans, algorithm development, grant applications, and preparation of presentations and publications. The candidate should work independently and in collaboration with faculty to solve problems posed by the clinical and laboratory investigators along the study design, data generation, collection and management process; interaction with bioinformatic experts, biostatistician program developers, computational scientists, health informatic experts as well as postdoc fellows from the Sidney Kimmel Comprehensive Cancer Center and the Bloomberg School of Public Health on our epigenomic data mining initiatives with the goal of translating these findings into therapeutic modalities for cancer patients. The applicant may share efforts between 1-3 labs.

    DUTIES AND RESPONSIBILITIES

    • Plan data management including determining type, format of data and types of documentation, considering privacy, confidentiality and other ethical issues
    • Facilitate acquisition of single cell sequencing data from core facilities
    • Clean data by coding missing data, fixing or deleting miscoded data, transforming variables into more useful formats, and annotating the data in proper way, use descriptive statistics to help characterize and summarize the data
    • Collaborate with clinical and scientific investigators in the breast cancer and biostat teams to propose ideas for new projects, design research, develop data plan, and prepare analyses with general direction from investigators
    • Apply different technical approaches to visualize the data and prepare publication-quality tables and graphs based on valid analysis
    • Lead or participate actively in the team responsible for designing and validating analysis data sets, programs, and statistical output products
    • Identify potential data problems from analytic queries and bring them to the attention of the team.
    • Demonstrate understanding of high dimensional data collection processes and data sets and share knowledge with collaborators.
    • Collaborate closely with investigators, and other team leadership to ensure that research study or project results and conclusions are presented accurately and without bias.
    • Demonstrate progress in ability to multi-task and manage time spent working with individual faculty members and on specific projects.
    • Participates in regularly schedule meetings with study investigators and team. Prepares progress reports as needed. Maintain appropriate systems for data organization.
    • Assure data quality for documentation and dissemination of data. Conduct and track specific activities to accomplish project goals, including evaluating and reporting data and documenting analytic procedures.
    • Able to work collaboratively in a team environment with a high degree of initiative and self-motivation.


    Supervision of Others:

    NA


    Equipment, Machine, or Tool Requirements:

    • Experience with computers and servers and knowledge of Linux/UNIX as well as other common operating systems such as Mac OS and Windows is necessary.
    • Experience with server configuration and troubleshooting preferred.
    • Ability to use the internet and web-based scholarly search engines.


    REQUIREMENTS

    Minimum Qualifications:

    Education:

    Required: Bachelor’s Degree in Statistics, Computer Science Bioinformatics and PhD in Statistics, Computer Science Bioinformatics or related field

    Experience:

    • Minimum of 3-4 years related experience in analyzing genomic data
    • Experience with code development, optimization, and testing


    Licensure, Certification, Registration:

    NA


    Special Knowledge, Skills, or Abilities / Competencies:

    • Proficiency with bioinformatics concepts, methods, and tools, with experience working in languages such as R or Python, leveraging Bioconductor and bioconda.
    • Coursework or work experience covering topics in statistics, molecular biology, genetics, and script-level programming.
    • Proficiency with genomic data, tools, and databases.
    • Familiarity with common computational biology tools.
    • Experience with experimental design principles, reproducible research principles,
    • and data storage, security, and safety.
    • Excellent interpersonal skills in consulting with researchers and understanding
    • their problems.
    • Excellent writing and verbal skills in the preparation and presentation of reports.
    • Excellent organizational skills and attention to details are required.
    • Must be detail-oriented, focused, creative, and independent
    • Proficiency in both written and spoken English with excellent communication


    Skills

    • Familiarity with common computational biology tools and software packages, such as Bioconductor
    • Familiarity with cancer epigenetics is preferred


    Contact Information:
    Dr. Eneda Toska

    etoska1@jhmi.edu

     

  • The Department of Anesthesiology and Critical Care Medicine (ACCM) and the Armstrong Institute Center for Health Care Human Factors (www.hopkinsmedicine.org/armstrong/humanfactors) at the Johns Hopkins University School of Medicine is recruiting a postdoc research fellow and/or a research coordinator.

    The ideal applicant will have experience in human factors engineering, cognitive systems engineering, human computer interaction, human factors psychology, or a related field. Experience in health care related work is highly desired, though not required. Experience or interest in both qualitative and quantitative analysis methods is also desired.

    The fellow will primarily be working with James H Abernathy, III, MD, MPH along with Ayse Gurses, PhD and other research team members on one or more funded research projects in the areas of human factors in patient safety and/ or health informatics. The individual will also have the opportunity to collaborate with other interdisciplinary research members of ACCM and the Armstrong Institute for Patient Safety and Quality.

    Primary Responsibilities:

    • Work collaboratively with study team on federally funded patient safety and human factors engineering-based research projects
    • Manage and perform data collection activities
    • Assist in the analysis and management of data (both qualitative and quantitative data analysis)
    • Assist in the preparation of study protocols and materials (e.g., IRB) and other essential functions
    • Conduct literature reviews and summarize findings
    • Author/co-author research manuscripts
    • Help with writing grant proposals, lead writing career grants (if interested and applicable)
       

    Education:

    • PhD or Master’s level degree or equivalent is required. Individuals with clinical backgrounds with interest in research will also be considered.
       

    Experience & Required Skills:

    • An individual with formal training and experience in human factors, cognitive systems engineering, human computer interaction, macroergonomics, sociotechnical systems design, or a related field.
    • An in-depth understanding of human cognition and usability design principles as they pertain to the design of technology to support and facilitate work (individual work and teamwork)
    • Knowledge of sociotechnical system approaches to research and design; an understanding of work system redesign to improve processes and outcomes.
    • Good understanding of related research processes and methodologies including qualitative and quantitative research methods.
    • Experience with knowledge elicitation methods (e.g., interviews, focus groups, and contextual inquiry), data driven design, iterative design processes, user-centered design, prototyping, and usability evaluations
    • Strong interest in conducting field research in health care environments
    • Ability to work independently as well as collaboratively as part of a research team
    • Ability to balance and prioritize tasks, and delivers timely outcomes
    • Excellent problem solving, organizational, writing and communication skills
       

    Nice to Have:

    • Knowledge/experience in ecological interface design and related design philosophies
    • Experience with prototyping methods and prototyping software (Adobe Creative Suite, PowerPoint, Balsamiq etc.)
    • Knowledge/experience with software/coding languages appropriate for the development of interfaces/ health IT
    • Experience with conducting usability evaluations (formative and summative)
    • Experience in research processes and qualitative methodologies for data collection & analysis, with corresponding software experience (e.g. semi-structured interviews, and thematic analysis with NVivo)
    • Familiarity with quantitative analysis methods and corresponding software experience (e.g., statistical analysis with SPSS)
    • Familiarity with the healthcare domain and experience conducting research in healthcare.
    • Experience in IRB protocol preparation
       

    Application deadline:

    • No specific deadline. However, applicants are encouraged to apply for the position as soon as possible. This position has an immediate starting date.
    • Apply now by sending applications to Megen Frierson at mfriers1@jhmi.edu   
    • Please provide a cover letter, CV, names and contact information of three references, and a personal statement (600 words max).
  • A postdoctoral position is available in the laboratory of Masanobu Komatsu, Ph.D. at the Cancer and Blood Disorders Institute/Johns Hopkins All Children’s Hospital to study the tumor immune microenvironment. High endothelial venules (HEV) are blood vessels specialized for recruiting naïve T cells and B cells. They serve a role as the gateways for lymphocyte entry into tumors and facilitate anti-tumor immune response. This project focuses on investigating how intratumoral HEVs shape the tumor immune landscape, promoting the formation of tertiary lymphoid structures (TLS), thereby enhancing immune checkpoint inhibition therapies. Candidates with a relevant training background in immunology or vascular biology should apply. Interested applicants should submit a single PDF file containing CV and a brief description of research interests and accomplishments to Dr. Komatsu.

    Masanobu Komatsu, Ph.D.
    Associate Professor
    Johns Hopkins School of Medicine
    Johns Hopkins All Children’s Hospital
    mkomats1@jhmi.edu

  • The Schreck-Pratilas laboratory is looking for a highly motivated Ph.D. graduate to become a postdoctoral fellow in our research laboratory in the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. Our group is focused on understanding and exploiting targetable vulnerabilities in RAF-dependent cancers, and aims to define mechanisms of resistance to targeted therapy and develop new treatments. We are specifically seeking a candidate interested in working on targeted therapy in glioma.

    Applicants must be highly independent, motivated, and a team player, with demonstrated success in experimental design and analysis, manuscript writing, and project management. Successful candidates must have a PhD in a related discipline and have excellent written and verbal communication skills.

    Duties and responsibilities:

    • Use in vitro and in vivo techniques to discover mechanism of effect and drug resistance in small molecule inhibitors
    • Manage their own and collaborative research projects in agreement and collaboration with the Principal Investigator
    • Identify and select best options for scientific strategies and research development based on literature reviews and collaboration with colleagues
    • Incorporate new technologies into the laboratory
    • Contribute to writing of scientific publications and grant applications


    Qualifications:

    • PhD. in Science, Biotechnology or equivalent
    • In-depth scientific knowledge and demonstrated competency in required assays and techniques used in the laboratory
    • Experience in analyzing results and contributing to scientific presentations
    • Demonstrated experience in experimental design, conduct, and analysis
    • Demonstrated scientific writing skills
    • Skill identifying problem areas and proposing and implementing solutions.


    Please respond by e-mail to Karisa Schreck (ksolt1@jhmi.edu) with a statement of interest, CV, and contact information for two references. 

  • The newly established Ruan Lab at The Johns Hopkins All Children's Hospital’s Institute for Fundamental Biomedical Research (IFBR) is recruiting two postdoctoral research fellows to study RNA metabolism in the context of health and diseases begin in July 2021.

    By taking advantage of a unique humanized liver mouse model, the Ruan Lab's research focuses on studying how RNA metabolism in human responses to nutrients and stress at the organism level and how dysregulation of these processes causes diseases and aging. The current research projects include:

    (1) Study the molecular mechanisms controlling the activity of our recently identified human lncRNAs associated with cardiometabolic traits.
    (2) Reveal how RNA degradation machinery, especially the 5' RNA degradation pathway, is regulated by overnutrition and explore its role in fatty liver diseases.
    (3) Identify nuclear-enriched lncRNAs that regulate pre-mRNA splicing in the liver and brain and explore their roles in aging.

    The Ruan lab is devoted to foster the career success of postdoctoral research fellows. By joining IFBR, the fellows' research will benefit from active collaboration with experts from the institute's Center for Metabolic Origins of Disease and Center for RNA Biology and the rich resource of Johns Hopkins school of medicine. Salary will follow the NIH standard. Located in St. Petersburg, Florida, IFBR will provide fellows a great work/life environment that Tampa Bay can offer.

    Successful candidates are expected to hold a Ph.D., M.D., or M.D./Ph.D. degree by July 2021. Previous research experience in RNA biology, animal experiments, and analysis of RNA-seq data is a plus. Please submit your application package, including a cover letter, CV, and contact information of at least three referees to Lorenzo Thomas at lthoma82@jhmi.edu.

  • The Trapecar Lab at the Johns Hopkins All Children’s Hospital and Institute for Fundamental Biomedical Research in St. Petersburg, Florida, is looking to hire two postdoctoral scientists.

    The focus of the group is the exploration of fundamental origins of immunometabolic diseases, such as IBD, metabolic syndrome and neurodegenerative disorders, by using exciting, multiorgan human-on-a-chip technologies and systems biology. To get a sense of the approach please consult www.trapecarlab.org and see two recent papers: Trapecar et al., Cell Systems 2020 and Trapecar et al., Science Advances, 2021.

    An ideal candidate will have strong conceptual and practical experience in two or more of the following areas: immunology, stem cell biology, molecular biology and tissue engineering. Types of tissues and organs that the lab is particularly interested in are mucosal tissue like intestine and lungs, liver, neuronal and adipose tissue as well as a wide range of circulating and tissue-resident immune cells. Common techniques used in the lab are cell culturing (primary cells, organoids, iPS cells), flow cytometry and cell sorting, generation and analysis of transcriptomic as well as metabolomic data (Chipseq, scRNAseq…), confocal microscopy, multiplexed cytokine/chemokine analysis (ELISAs, Luminex) and use of bioengineered tools like human-on-a-chip platforms to study human multiorgan interactions.

    Successful candidates must be capable to work in highly multidisciplinary research teams and have a demonstrated track record of success in independent scientific research. Strong applicants will exhibit significant basic science understanding, scientific rigor, motivation, and an ability to originate, carry out, and publish significant original research in collaboration with their JHU mentors. Strong written and verbal English language skills are required.

    The rapidly growing new Institute for Fundamental Biomedical Research is part of the Johns Hopkins All Children’s Hospital in St. Petersburg, Florida, and the Johns Hopkins University (JHU) School of Medicine ecosystem. It represents a superbly equipped research environment that aims to connect basic and clinical researchers to solve some of the biggest medical challenges. Trainees and postdoctoral scientists have also full access to resources available at the main JHU Baltimore campus and are strongly encouraged to participate in JHU-wide activities and collaborations. The lab and institute are fully committed to the candidate’s career development and path to independence.

    St. Petersburg offers a great quality of life in terms of affordability, pristine nature, close proximity to Tampa bay’s international airport, and vibrant cultural life.

    If interested in the position, please submit a CV and brief description of scientific interests to mtrapec1@jhmi.edu.

  • Job Description. The Computational Cardiology Lab (PI: Natalia Trayanova, trayanovalab.org) at the Department of Biomedical Engineering and the Alliance for Cardiovascular Diagnostic Innovation (heartadvance.jhu.edu), Johns Hopkins University, seeks computational cardiac electrophysiology postdoctoral fellows or research scientists. Multiple positions are available. The Lab is developing and translating to the clinic personalized computational digital-twin technologies and machine learning approaches for the prognosis and treatment of heart rhythm disorders. Our work focuses on using computational heart modeling to predict risk of sudden cardiac death or other adverse cardiac outcomes. We design personalized treatment interventions for atrial fibrillation and ventricular arrhythmias based on computational modeling with the goal to maximize clinical procedure success and minimize the arrhythmia recurrence and re-hospitalization. We are currently involved in a clinical trial testing the utility of cardiac modeling in ablation targeting for persistent atrial fibrillation. We also conduct research exploring the mechanisms for arrhythmias. The Postdoctoral Scholars/ Research Scientists will perform research on NIH-funded translational projects.

    Job Requirements. Candidates must hold a PhD in biomedical engineering/bioengineering, applied math, physics, biophysics, or closely related fields and must have lead-author publication(s) in computational modeling of the heart. Candidates should also have strong communication skills and the ability to work both independently and as part of a collaborative team. Prior experience in cardiac modeling and programming skills is a must.

    Job Information. To apply, please send a CV, cover letter, and contact information for three references to Leslie Thompson, lthomp10@jhu.edu. Inquiries can be directed at Dr. Natalia Trayanova, ntrayanova@jhu.edu. The positions will remain open until filled. Salary depends on experience.

  • Description
    Aim: To equip a performing arts medicine clinician or performance science professional with a comprehensive skill set in preparation for leadership of a department/division within an academic institution, performing arts company, professional organization, or similar group.

    The Post-Doctoral Fellow in Performing Arts Health, Science, and Education reports to and is supported by a team of faculty and staff from the Peabody Institute and Johns Hopkins Medicine’s Department of Physical Medicine and Rehabilitation. The Fellow’s research activity will be mentored by a faculty mentor from PM&R, while education and administrative responsibilities will be overseen by staff from the Peabody Clinic, student affairs, and the office of the Associate Dean for Innovation, Interdisciplinary Partnerships, & Community Initiatives.

    Activities within the following Programmatic Pillars will be tailored to the Fellow’s clinical expertise, professional background, and future career interests:

    1. Education (clinical, performing arts pedagogy, community, prevention, health awareness)
    2. Preventative Health Strategies (musculoskeletal, mindset/mental health, nutrition, fitness)
    3. Systems Navigation (academic, healthcare, industry, professional organizations, community)
    4. Administration (leadership and operations management)
    5. Investigation (injury surveillance, population health, clinical practice/outcomes, value-based care, performance physiology, biomechanics)
    6. Advocacy & Policy (industry and professional advocacy, health policy, occupational health, government policy)

    The work of this 12-month fellowship (renewable) may include:

    Education (ca. 50% of time)

    • Assist with coordination and program delivery for Peak Performance Fundamentals orientation program for incoming students
    • Debrief screenings with students
    • Provide weekly advisement sessions and coordinate advisement session team calendar
    • Liaise with Conservatory and Preparatory performance faculty as appropriate
    • Liaise with Student Affairs office as appropriate
    • Develop and deliver wellness/fitness/injury prevention programming and non-credit classes as appropriate
    • Teach wellness/injury prevention curriculum as needed and as appropriate
    • Coordinate backstage care


    Research (ca. 25%)

    • Coordinate yearly data collection from student screenings, clinic usage, educational programs to assist with program evaluation
    • Serve as PI or Co-PI in clinical and educational research studies emanating from Peabody Clinic and the department of Physical Medicine and Rehabilitation
    • Coordinate research studies and assist with grant applications as appropriate
    • Prepare and present research at Performing Arts conferences


    Administrative Support (ca. 25%)

    • Provide administrative support for yearly screenings
    • Assist with clinic marketing/communication/outreach to faculty and students
    • Oversee on-campus programming for fitness and wellness
    • If appropriate, provide direct clinical services


    Salary: $54,000

    Preferred start date: July 1, 2021

    Qualifications

    • Doctorate or clinical doctorate in the fields of Medicine, Osteopathy, Occupational Therapy, Physical Therapy, Speech Language Pathology, Athletic Training, Chiropractic, Psychology, Nutrition, Psychology, Applied Physiology, Biomechanics/Kinesiology, Exercise Science, Public Health, or Education
    • Preference given to candidates with a demonstrated commitment to and/or proficiency/accomplishment in the performing arts
    • Curriculum design/teaching experience in higher ed and/or community context


    Application Instructions
    Please submit a cover letter regarding your interest in the position, a C.V., and a research or curriculum/teaching sample in one of the following formats:

    • Dissertation abstract
    • Presentation
    • Publication
    • Syllabus
    • Video
 
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