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Open Postdoctoral Fellowship Positions at SOM-JHU

Below are current postdoctoral fellowship positions that are open at SOM-JHU. For additional details on an open position, contact the primary faculty on the listing.

  • Primary Faculty: Gene Fridman, Ph.D.

    Overall Purpose
    Miniaturize the Safe Direct Current Neural Stimulation (SDCS) system to an implantable size device and develop the electrodes for this implantable system. This is a considerable engineering challenge that requires developing a small-scale reliable microfluidic circuit that includes self-actuated microfluidic valves to control ionic current flow, function for millions of cycles, and maintain low power operation.

    Key Responsibilities:

    • Lead continuing R&D efforts of the SDCS miniaturization, reliability, and multi-channel capability.
    • Investigate the literature to apply relevant technologies to the microfluidic design.
    • Work collaboratively with others on the team focusing on electronic design and neurophysiology experiments.
    • Author manuscripts and patents associated with the innovations toward these technological developments.


    Skills and Qualifications:
    Required:

    • PhD or 5+ years experience in a relevant engineering discipline
    • Laboratory hands-on experience in designing microfluidics
    • Laboratory hands-on experience with electronic circuits


    Preferred:

    • Good chemistry background
    • Understanding of biocompatibility issues
    • Firmware programming experience


    Position Duration: Initial contract will be for 1 year, extensible for up to 4 years supported by R01 NIH grants.

    Background
    Safe Direct Current Stimulator (SDCS) technology that we are developing in our laboratory will enable creation of a new class of bioelectronic prostheses that excite, inhibit, and modulate the sensitivity of neurons. Vestibular implants, cochlear implants, and essentially all other chronically implantable neuroelectronic prostheses rely on charge-balanced, biphasic pulses or other forms of alternating current (AC) to excite neural or muscular activity without driving electrochemical reactions that would otherwise liberate toxic substances at the electrode-saline interface. All of these devices are constrained to excite the neural tissue in which they are implanted. Inhibition is difficult to achieve with these devices, because the need to avoid a net charge flow above a small threshold mandates the use of brief, charge-balanced pulses.

    Safe Direct Current Stimulation (SDCS) technology can inhibit, excite, or sensitize neurons. Conceptually, the SDCS converts alternating charge balanced-pulses delivered to two metal electrodes submerged in an electrolyte within a device to direct ionic current delivered to the tissue at the output of the device via electrolyte-gel-filled tubes positioned near the target neurons.

    Wide range of neuroengineering applications could be revolutionized with this technology: some examples are the vestibular prosthesis for balance disorders, pain suppression to control chronic neuropathic pain, asthma attack suppression, and tinnitus suppression.

    Apply by email with cv or resume to: Gene Fridman (gfridma1@jhmi.edu)
  • Co-Primary investigators: Chloe Thio, MD and Ashwin Balagopal, MD

    Description of position:
    We are seeking a highly motivated postdoctoral researcher who is interested in applying high resolution molecular techniques to liver tissue samples. The overall goal of this project is to gain insight into hepatitis B transcription at the level of the single hepatocyte before and after anti-HBV therapy. Since HBV transcription is central to HBV replication, such data are needed to advance the HBV cure field. This is a translational project that will apply high-resolution molecular techniques to tissues from HBV-infected people.

    The laboratory is based in the Department of Medicine, Division of Infectious Diseases in the Johns Hopkins University School of Medicine. One of the major goals of the group is to advance knowledge of HBV virology and immunology through translational projects that utilize clinical samples to ask critical questions. Specific projects include 1) utilizing droplet digital PCR (ddPCR) to amplify HBV DNA and RNA from single hepatocytes in people with various stages of hepatitis B and with and without treatment, 2) using RNA seq to probe biological differences between hepatocytes with and without transcriptionally silent cccDNA, 3) role of epigenetics in transcriptional silencing of cccDNA.

    Job Qualifications
    PhD in molecular biology or related field
    Experience/skills in the following areas is desired:

    • Background in hepatitis B or virology
    • Experience with standard molecular techniques, sequencing, and ideally with ddPCR
    • Strong communication and interpersonal skills
    • Fluency in written and spoken English


    Instructions for applying

    To apply please email the following to Dr. Thio (cthio@jhmi.edu) and Dr. Balagopal (abalago1@jhmi.edu)

    • Cover letter describing research interests, career goals, prior experience
    • Curriculum vitae
    • Writing sample (published paper or manuscript draft)
    • Names and contact information of 2-3 references


    Applications will be reviewed on a rolling basis starting March 29th 2021 until the position is filled

  • Primary Faculty: Luigi Adamo, MD Ph.D.

    The Adamo Lab in The Johns Hopkins University Division of Cardiology is seeking a post-doctoral fellow to lead cutting edge research in cardiac-immunology.

    We are looking for a highly motivated and independent researcher with a Ph.D. in immunology, biology, or a related field.

    Candidates must have first-author publications and proven research ability in at least one of the following areas: immunology, models of cardiac injury, cardiac physiology, lymphocyte biology, or aging. Hands-on experience in translational animal models is also required.

    Experience in the following techniques is helpful but not required: flow cytometry, immunohistochemistry, and immunofluorescence.

    A successful candidate will have a strong work ethic, strong organizational skills, excellent critical thinking abilities, excellent ability to work as part of a team and a desire to push the boundaries of existing knowledge. The postdoctoral researcher will work under supervision but will be expected to lead methods development, lead manuscript and grant writing efforts, conduct independent research and supervise junior researchers.

    We offer multifaceted scientific projects, strong scientific collaborations, and attentive mentoring in the context of the vibrant, word class research environment of Johns Hopkins University. We are passionate about discovery and drug development. If you share our passion and fit the above description, we would love to hear from you.

    Adamo Cardiac-Imunology Lab
    ladamo2@jhmi.edu
    http://hopkinsmedicine.org/adamo-lab

  • Job Title: Research Fellow
    Working Title: Research Fellow
    Job Family: Research
    FLSA: Exempt

    Department: Oncology (Cancer Epigenetics and Therapeutic Resistance)

    Reports to: Principal Investigators: Drs. Eneda Toska and Elana Fertig

    The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University is recruiting an individual to lead analyses on epigenomics analyses such as (ChIP-seq, ATAC-seq and RNA-seq) and single cell analyses in cancer models. This person will be active in the data pre-processing stages as well as analysis and interpretation of results.

    The Toska lab integrates biochemistry, cell signaling, genomics and epigenomics at bulk and single cell level to study the fundamental processes by which epigenetic regulators regulate transcription, have the ability to drive tumorigenesis and dictate therapeutic response in breast cancer. The Fertig lab develops time course models of therapeutic resistance and performs single cell technology development. Her computational methods are used to determine the molecular mechanisms of therapeutic resistance from multi-platform genomics and epigenomics data. The successful candidate will become a fundamental component of this multidisciplinary team with mentorship in both computational and biological processes affecting therapeutic response in cancer.

    Eligible candidate will be involved in designing and developing analysis plans to address biological hypotheses in our ChIP-seq/ATAC-seq/RNA-seq and RNA-seq and ATAC-seq at the single level acquired from breast cancer models such as cell lines, organoids, and patients treated with targeted therapies. The candidate will interact daily with other data analysts within the Institute, as well as Genomics experts, and clinicians. This position requires collaboration with clinical and scientific investigators in research/study design, data analysis plans, algorithm development, grant applications, and preparation of presentations and publications. The candidate should work independently and in collaboration with faculty to solve problems posed by the clinical and laboratory investigators along the study design, data generation, collection and management process; interaction with bioinformatic experts, biostatistician program developers, computational scientists, health informatic experts as well as postdoc fellows from the Sidney Kimmel Comprehensive Cancer Center and the Bloomberg School of Public Health on our epigenomic data mining initiatives with the goal of translating these findings into therapeutic modalities for cancer patients. The applicant may share efforts between 1-3 labs.

    DUTIES AND RESPONSIBILITIES

    • Plan data management including determining type, format of data and types of documentation, considering privacy, confidentiality and other ethical issues
    • Facilitate acquisition of single cell sequencing data from core facilities
    • Clean data by coding missing data, fixing or deleting miscoded data, transforming variables into more useful formats, and annotating the data in proper way, use descriptive statistics to help characterize and summarize the data
    • Collaborate with clinical and scientific investigators in the breast cancer and biostat teams to propose ideas for new projects, design research, develop data plan, and prepare analyses with general direction from investigators
    • Apply different technical approaches to visualize the data and prepare publication-quality tables and graphs based on valid analysis
    • Lead or participate actively in the team responsible for designing and validating analysis data sets, programs, and statistical output products
    • Identify potential data problems from analytic queries and bring them to the attention of the team.
    • Demonstrate understanding of high dimensional data collection processes and data sets and share knowledge with collaborators.
    • Collaborate closely with investigators, and other team leadership to ensure that research study or project results and conclusions are presented accurately and without bias.
    • Demonstrate progress in ability to multi-task and manage time spent working with individual faculty members and on specific projects.
    • Participates in regularly schedule meetings with study investigators and team. Prepares progress reports as needed. Maintain appropriate systems for data organization.
    • Assure data quality for documentation and dissemination of data. Conduct and track specific activities to accomplish project goals, including evaluating and reporting data and documenting analytic procedures.
    • Able to work collaboratively in a team environment with a high degree of initiative and self-motivation.


    Supervision of Others:

    NA


    Equipment, Machine, or Tool Requirements:

    • Experience with computers and servers and knowledge of Linux/UNIX as well as other common operating systems such as Mac OS and Windows is necessary.
    • Experience with server configuration and troubleshooting preferred.
    • Ability to use the internet and web-based scholarly search engines.


    REQUIREMENTS

    Minimum Qualifications:

    Education:

    Required: Bachelor’s Degree in Statistics, Computer Science Bioinformatics and PhD in Statistics, Computer Science Bioinformatics or related field

    Experience:

    • Minimum of 3-4 years related experience in analyzing genomic data
    • Experience with code development, optimization, and testing


    Licensure, Certification, Registration:

    NA


    Special Knowledge, Skills, or Abilities / Competencies:

    • Proficiency with bioinformatics concepts, methods, and tools, with experience working in languages such as R or Python, leveraging Bioconductor and bioconda.
    • Coursework or work experience covering topics in statistics, molecular biology, genetics, and script-level programming.
    • Proficiency with genomic data, tools, and databases.
    • Familiarity with common computational biology tools.
    • Experience with experimental design principles, reproducible research principles,
    • and data storage, security, and safety.
    • Excellent interpersonal skills in consulting with researchers and understanding
    • their problems.
    • Excellent writing and verbal skills in the preparation and presentation of reports.
    • Excellent organizational skills and attention to details are required.
    • Must be detail-oriented, focused, creative, and independent
    • Proficiency in both written and spoken English with excellent communication


    Skills

    • Familiarity with common computational biology tools and software packages, such as Bioconductor
    • Familiarity with cancer epigenetics is preferred


    Contact Information:
    Dr. Eneda Toska

    etoska1@jhmi.edu

     

  • The Department of Anesthesiology and Critical Care Medicine (ACCM) and the Armstrong Institute Center for Health Care Human Factors (www.hopkinsmedicine.org/armstrong/humanfactors) at the Johns Hopkins University School of Medicine is recruiting a postdoc research fellow and/or a research coordinator.

    The ideal applicant will have experience in human factors engineering, cognitive systems engineering, human computer interaction, human factors psychology, or a related field. Experience in health care related work is highly desired, though not required. Experience or interest in both qualitative and quantitative analysis methods is also desired.

    The fellow will primarily be working with James H Abernathy, III, MD, MPH along with Ayse Gurses, PhD and other research team members on one or more funded research projects in the areas of human factors in patient safety and/ or health informatics. The individual will also have the opportunity to collaborate with other interdisciplinary research members of ACCM and the Armstrong Institute for Patient Safety and Quality.

    Primary Responsibilities:

    • Work collaboratively with study team on federally funded patient safety and human factors engineering-based research projects
    • Manage and perform data collection activities
    • Assist in the analysis and management of data (both qualitative and quantitative data analysis)
    • Assist in the preparation of study protocols and materials (e.g., IRB) and other essential functions
    • Conduct literature reviews and summarize findings
    • Author/co-author research manuscripts
    • Help with writing grant proposals, lead writing career grants (if interested and applicable)
       

    Education:

    • PhD or Master’s level degree or equivalent is required. Individuals with clinical backgrounds with interest in research will also be considered.
       

    Experience & Required Skills:

    • An individual with formal training and experience in human factors, cognitive systems engineering, human computer interaction, macroergonomics, sociotechnical systems design, or a related field.
    • An in-depth understanding of human cognition and usability design principles as they pertain to the design of technology to support and facilitate work (individual work and teamwork)
    • Knowledge of sociotechnical system approaches to research and design; an understanding of work system redesign to improve processes and outcomes.
    • Good understanding of related research processes and methodologies including qualitative and quantitative research methods.
    • Experience with knowledge elicitation methods (e.g., interviews, focus groups, and contextual inquiry), data driven design, iterative design processes, user-centered design, prototyping, and usability evaluations
    • Strong interest in conducting field research in health care environments
    • Ability to work independently as well as collaboratively as part of a research team
    • Ability to balance and prioritize tasks, and delivers timely outcomes
    • Excellent problem solving, organizational, writing and communication skills
       

    Nice to Have:

    • Knowledge/experience in ecological interface design and related design philosophies
    • Experience with prototyping methods and prototyping software (Adobe Creative Suite, PowerPoint, Balsamiq etc.)
    • Knowledge/experience with software/coding languages appropriate for the development of interfaces/ health IT
    • Experience with conducting usability evaluations (formative and summative)
    • Experience in research processes and qualitative methodologies for data collection & analysis, with corresponding software experience (e.g. semi-structured interviews, and thematic analysis with NVivo)
    • Familiarity with quantitative analysis methods and corresponding software experience (e.g., statistical analysis with SPSS)
    • Familiarity with the healthcare domain and experience conducting research in healthcare.
    • Experience in IRB protocol preparation
       

    Application deadline:

    • No specific deadline. However, applicants are encouraged to apply for the position as soon as possible. This position has an immediate starting date.
    • Apply now by sending applications to Carol Stokeling at cstokel1@jhmi.edu
    • Please provide a cover letter, CV, names and contact information of three references, and a personal statement (600 words max).
  • A postdoctoral position is available in the laboratory of Masanobu Komatsu, Ph.D. at the Cancer and Blood Disorders Institute/Johns Hopkins All Children’s Hospital to study the tumor immune microenvironment. High endothelial venules (HEV) are blood vessels specialized for recruiting naïve T cells and B cells. They serve a role as the gateways for lymphocyte entry into tumors and facilitate anti-tumor immune response. This project focuses on investigating how intratumoral HEVs shape the tumor immune landscape, promoting the formation of tertiary lymphoid structures (TLS), thereby enhancing immune checkpoint inhibition therapies. Candidates with a relevant training background in immunology or vascular biology should apply. Interested applicants should submit a single PDF file containing CV and a brief description of research interests and accomplishments to Dr. Komatsu.

    Masanobu Komatsu, Ph.D.
    Associate Professor
    Johns Hopkins School of Medicine
    Johns Hopkins All Children’s Hospital
    mkomats1@jhmi.edu

  • The newly established Ruan Lab at The Johns Hopkins All Children's Hospital’s Institute for Fundamental Biomedical Research (IFBR) is recruiting two postdoctoral research fellows to study RNA metabolism in the context of health and diseases begin in July 2021.

    By taking advantage of a unique humanized liver mouse model, the Ruan Lab's research focuses on studying how RNA metabolism in human responses to nutrients and stress at the organism level and how dysregulation of these processes causes diseases and aging. The current research projects include:

    (1) Study the molecular mechanisms controlling the activity of our recently identified human lncRNAs associated with cardiometabolic traits.
    (2) Reveal how RNA degradation machinery, especially the 5' RNA degradation pathway, is regulated by overnutrition and explore its role in fatty liver diseases.
    (3) Identify nuclear-enriched lncRNAs that regulate pre-mRNA splicing in the liver and brain and explore their roles in aging.

    The Ruan lab is devoted to foster the career success of postdoctoral research fellows. By joining IFBR, the fellows' research will benefit from active collaboration with experts from the institute's Center for Metabolic Origins of Disease and Center for RNA Biology and the rich resource of Johns Hopkins school of medicine. Salary will follow the NIH standard. Located in St. Petersburg, Florida, IFBR will provide fellows a great work/life environment that Tampa Bay can offer.

    Successful candidates are expected to hold a Ph.D., M.D., or M.D./Ph.D. degree by July 2021. Previous research experience in RNA biology, animal experiments, and analysis of RNA-seq data is a plus. Please submit your application package, including a cover letter, CV, and contact information of at least three referees to Lorenzo Thomas at lthoma82@jhmi.edu.

  • The Trapecar Lab at the Johns Hopkins All Children’s Hospital and Institute for Fundamental Biomedical Research in St. Petersburg, Florida, is looking to hire two postdoctoral scientists.

    The focus of the group is the exploration of fundamental origins of immunometabolic diseases, such as IBD, metabolic syndrome and neurodegenerative disorders, by using exciting, multiorgan human-on-a-chip technologies and systems biology. To get a sense of the approach please consult www.trapecarlab.org and see two recent papers: Trapecar et al., Cell Systems 2020 and Trapecar et al., Science Advances, 2021.

    An ideal candidate will have strong conceptual and practical experience in two or more of the following areas: immunology, stem cell biology, molecular biology and tissue engineering. Types of tissues and organs that the lab is particularly interested in are mucosal tissue like intestine and lungs, liver, neuronal and adipose tissue as well as a wide range of circulating and tissue-resident immune cells. Common techniques used in the lab are cell culturing (primary cells, organoids, iPS cells), flow cytometry and cell sorting, generation and analysis of transcriptomic as well as metabolomic data (Chipseq, scRNAseq…), confocal microscopy, multiplexed cytokine/chemokine analysis (ELISAs, Luminex) and use of bioengineered tools like human-on-a-chip platforms to study human multiorgan interactions.

    Successful candidates must be capable to work in highly multidisciplinary research teams and have a demonstrated track record of success in independent scientific research. Strong applicants will exhibit significant basic science understanding, scientific rigor, motivation, and an ability to originate, carry out, and publish significant original research in collaboration with their JHU mentors. Strong written and verbal English language skills are required.

    The rapidly growing new Institute for Fundamental Biomedical Research is part of the Johns Hopkins All Children’s Hospital in St. Petersburg, Florida, and the Johns Hopkins University (JHU) School of Medicine ecosystem. It represents a superbly equipped research environment that aims to connect basic and clinical researchers to solve some of the biggest medical challenges. Trainees and postdoctoral scientists have also full access to resources available at the main JHU Baltimore campus and are strongly encouraged to participate in JHU-wide activities and collaborations. The lab and institute are fully committed to the candidate’s career development and path to independence.

    St. Petersburg offers a great quality of life in terms of affordability, pristine nature, close proximity to Tampa bay’s international airport, and vibrant cultural life.

    If interested in the position, please submit a CV and brief description of scientific interests to mtrapec1@jhmi.edu.

  • Job Description. The Computational Cardiology Lab (PI: Natalia Trayanova, trayanovalab.org) at the Department of Biomedical Engineering and the Alliance for Cardiovascular Diagnostic Innovation (heartadvance.jhu.edu), Johns Hopkins University, seeks computational cardiac electrophysiology postdoctoral fellows or research scientists. Multiple positions are available. The Lab is developing and translating to the clinic personalized computational digital-twin technologies and machine learning approaches for the prognosis and treatment of heart rhythm disorders. Our work focuses on using computational heart modeling to predict risk of sudden cardiac death or other adverse cardiac outcomes. We design personalized treatment interventions for atrial fibrillation and ventricular arrhythmias based on computational modeling with the goal to maximize clinical procedure success and minimize the arrhythmia recurrence and re-hospitalization. We are currently involved in a clinical trial testing the utility of cardiac modeling in ablation targeting for persistent atrial fibrillation. We also conduct research exploring the mechanisms for arrhythmias. The Postdoctoral Scholars/ Research Scientists will perform research on NIH-funded translational projects.

    Job Requirements. Candidates must hold a PhD in biomedical engineering/bioengineering, applied math, physics, biophysics, or closely related fields and must have lead-author publication(s) in computational modeling of the heart. Candidates should also have strong communication skills and the ability to work both independently and as part of a collaborative team. Prior experience in cardiac modeling and programming skills is a must.

    Job Information. To apply, please send a CV, cover letter, and contact information for three references to Melissa Foley-King at mfoleyk1@jhu.edu. Inquiries can be directed at Dr. Natalia Trayanova, ntrayanova@jhu.edu. The positions will remain open until filled. Salary depends on experience.

  • This fellowship will equip a performing arts medicine clinician or performance science professional with a comprehensive skill set in preparation for leadership of a department/division within an academic institution, performing arts company, professional organization, or similar group.

    The Post-Doctoral Fellow in Performing Arts Health, Science and Education reports to and is supported by a team of faculty and staff from the Peabody Institute and Johns Hopkins Medicine’s Department of Physical Medicine and Rehabilitation. The Fellow’s research activity will be mentored by Dr. Preeti Raghavan, while education and administrative responsibilities will be overseen by staff from Peabody’s JHRN clinic, student affairs department, and the office of the Associate Dean for Innovation, Interdisciplinary Partnerships & Community Initiatives. This is a 12-month renewable fellowship.

    Activities within the following Programmatic Pillars will be tailored to the Fellow’s clinical expertise, professional background, and future career interests:

    1. Education (clinical, performing arts pedagogy, community, prevention, health awareness)
    2. Preventative Health Strategies (musculoskeletal, mindset/mental health, nutrition, fitness)
    3. Systems Navigation (academic, healthcare, industry, professional organizations, community)
    4. Administration (leadership and operations management)
    5. Investigation (injury surveillance, population health, clinical practice/outcomes, value-based care, performance physiology, biomechanics)
    6. Advocacy & Policy (industry and professional advocacy, health policy, occupational health, government policy)

    Successful candidates will hold a PhD, terminal degree, or clinical doctorate in PT, OT, SLP, MD, DO, DC, Psychology, Nutrition, Psychology, Applied Physiology, Biomechanics/Kinesiology, Public Health, Education. Preference will be given to candidates with a demonstrated commitment to and/or proficiency/accomplishment in the performing arts, as well as experience with curriculum design and teaching in higher ed and/or community context. Please see further details and submit your application package at apply.interfolio.com/86281 including a cover letter, C.V., and a research or curriculum/teaching sample. For questions regarding the position, please contact sarah.hoover@jhu.edu.

  • Job Description:
    The Johns Hopkins University Department of Dermatology Cutaneous Oncology Fellowship Program offers a unique clinical and research experience across the disciplines of cutaneous oncology including cutaneous lymphoma, melanoma, skin cancer in high risk/ immunocompromised (solid organ transplant patients) and supportive oncodermatology. Fellows will work with our expert clinicians and physician scientists, to gain skills in clinical and translational research. The clinical fellows are expected to productively participate in the clinical and translational research activities of the Department of Dermatology, publish scholarly clinical research articles during their fellowship and make at least one scientific presentation. Fellows will assist in developing protocols for clinical research studies, work with the Institutional Review Board (IRB), recruit study patients, conduct study visits, and learn/ improve data management skills. Fellows will also interact with pathology, oncology and transplant teams in multidisciplinary patient care. They will work with basic scientists on translational research projects. Fellows will have the opportunity for organizational leadership role in organizing local cutaneous oncology meetings.

    Requirements
    Position open to:

    • 3rd to 5th year medical student or
    • MD or MD/PhD degree and completion of at least 1 year PGY1 residency (by June 30) or
    • Fellows may also have already completed dermatology residency

    Updated CV and 3 references
    All available USMLE transcripts (e.g., Steps 1, 2 CK, 2 CS and 3)
    Maryland State Medical License; at the time of the beginning of the fellowship (July 1), if applicable
    Preference will be given to those who have completed a residency in internal medicine or dermatology and have an interest in an academic career.
    Interested applicants should send a brief statement of their interests and career goals with the aforementioned items

    Dates
    This is a one to two-year fellowship upon mutual agreement. Each appointed term runs from July 1st through June 30th, or upon agreement.

    Contact:
    Courtney C. Elcock
    Sr. Administrative and Development Coordinator
    (410)955-8662
    (410)955-8645(fax)
    celcock1@jhmi.edu

  • Primary Faculty: Darrell J. Gaskin, Ph.D.

    This announcement is for a postdoctoral fellowship in the Training in Orthopedic Team Science (TOTS) program at the Bloomberg School of Public Health at Johns Hopkins University. The postdoctoral fellow will work with a multidisciplinary team from the Bloomberg School of Public Health and the Department of Orthopedic Surgery in the School of Medicine. This multidisciplinary team will investigate the economic implications of issues of diversity within the field of orthopedics for patients and providers. This team will consist of the postdoctoral fellow, an orthopedic surgery resident physician trainee, a clinical mentor and research mentor.

    This position is funded by a T32 grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health. This postdoctoral position has a two-year training period. The postdoctoral fellow will work in partnership with an orthopedic surgery resident physician trainee to apply experimental research methods in economics to musculoskeletal healthcare disparities. One of the goals of this program is for the resident and the postdoctoral fellow to develop complementary projects on disparities in musculoskeletal healthcare.

    The postdoctoral fellow will be mentored by Darrell J. Gaskin, PhD, Director of the Johns Hopkins Center for Health Disparities Solutions and the William C. and Nancy F. Richardson Professor in Health Policy. The TOTS team will include an orthopedic surgery resident physician trainee and their clinical mentor from the Department of Orthopedic Surgery. This is an in-person position; however, while COVID pandemic protocols are in place, the postdoctoral fellow will be expected to work from home.

    Only U.S. citizens, non-citizen nationals, or those lawfully admitted for permanent residence are eligible for this position.
    Qualified applicants for the postdoctoral fellowship should have the following:

    1) A Ph.D. in Economics, Health Economics, Epidemiology, or related field. (It is possible to apply for the position if one expects to achieve a doctoral degree by June 30, 2021).
    2) Ability to conduct independent economic research, apply experimental methods to healthcare economics, and assume responsibility for the development and completion of research papers.
    3) Demonstrated ability to work as part of a research team on collaborative projects with successful completion of project aims and deadlines.

    Applications will be considered on a rolling basis until the position is filled. Please submit applications via email to Dr. Darrell J. Gaskin at HCHDS@jhu.edu.

    Completed applications should include:
    1) A 2-page research statement describing one’s research interests and how they relate to disparities in musculoskeletal healthcare.
    2) A current CV.
    3) A job market paper.
    4) A letter of support from one’s dissertation advisor or a member of their dissertation committee.
    5) Two letters of recommendation.

  • Applications are invited for a full-time, NIH-funded post-doctoral position available in the Romerio Lab at the Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine in Baltimore, MD. The position is open to a highly motivated postdoctoral fellow to join our efforts to investigate the mechanisms of HIV-1 persistence with the aim of developing a functional cure.

    The selected candidate will investigate the HIV-1 antisense gene ASP, and will contribute to elucidate their role in viral replication and persistence, using cellular and molecular approaches in the context of in vitro and in vivo models. Moreover, the candidate will contribute to develop a gene therapy-based approach to achieve a functional cure for HIV-1.

    Experience with the following techniques is highly preferred: mammalian cell culture (primary cells and cell lines); flow cytometry; transfection; transduction; DNA, RNA and protein extraction; RT-qPCR; western blotting; mouse models.

    Writing manuscripts, delivering oral presentations, and attending national and international scientific conferences related to the lab's research focus will be strongly encouraged.

    To apply, send cover letter, curriculum vitae, and name and contact information of three references to Dr. Fabio Romerio at fromeri2@jhmi.edu.

  • A postdoctoral fellow position is currently open in Dr. Rui Zhou’s laboratory in the Departments of Medicine, Biological Chemistry and Oncology, Johns Hopkins University School of Medicine and Center for RNA Biology, Johns Hopkins All Children’s Hospital. The Zhou laboratory is employing a combination of biochemical, genetic, genomic and functional genomic approaches to study the molecular mechanism governing the biogenesis of regulatory non-coding RNAs, and to elucidate their function in innate immunity, neuro-development, metabolism and tumor formation.

    We have identified and characterized key regulators of RNA interference and antiviral defense (Zhou et al, Molecular Cell, 2008; Sabin, Zhou et al, Cell, 2009; Czech & Zhou et al, Molecular Cell, 2009; Ni, Zhou & Czech et al, Nature Methods, 2011; Xiong et al, PNAS, 2013; Lim et al, RNA Biology, 2014; Xiong et al, PLoS Genetics, 2015; Molleston et al, Genes & Development, 2016). In addition, we have established microRNA-34 as a crucial modulator of innate immunity and steroid hormone signaling (Xiong et al, PLoS Pathogens, 2016). Furthermore, we have identified a group of circular RNAs that impact innate immunity and neuro-development (Xiong et al, submitted; Liu et al, in preparation). Moreover, we are investigating the function and regulation of circular RNAs in lipid metabolism and antiviral immunity. Ongoing work focuses on elucidating the underlying molecular mechanism using both animal models and cultured cells. We seek a postdoctoral fellow to drive these exciting projects forward.

    Required skills: The successful candidate must have a strong background in at least one of the following areas: biochemistry, molecular biology, and genetics, and should be highly motivated, and superb at both bench work and critical thinking.

    This position is expected to start immediately, and will be based at the Center for RNA Biology, Johns Hopkins All Children’s Hospital in St. Petersburg, Florida, which is known for its pleasant weather, low cost of living, and beautiful beaches. Salary and fringe benefits will be compliant with guidelines established by the Johns Hopkins University School of Medicine. The Zhou Lab is located in the newly completed 225,000-square-foot state-of-the-art Research & Education Building. We enjoy interactions with a vibrant and collegial group of Departmental colleagues working on RNA Biology, gene regulation, vascular biology, immunology, oncology and metabolism. Interested candidates please send CV and relevant publications to Dr. Rui Zhou: rzhou13@jhmi.edu.

  • General Description
    We are seeking recent Ph.D. graduates to join a postdoctoral fellowship program developing approaches to clinically relevant molecular characterization of patient-derived three dimensional models of pancreatic cancer. The fellowship program is jointly advised by faculty from the Department of Surgery and Oncology as part of the Pancreatic Cancer Multidisciplinary Laboratory and the Pancreatic Cancer Precision Medicine Center of Excellence at Johns Hopkins Hospital and Johns Hopkins Medical Institutions. This unique opportunity will allow postdoctoral fellows to gain academic research experience with direct translational relevance and implementation of patient-centered clinical research projects. Successful candidates will have an interest in improving techniques in rapid tumor modeling and clinically-relevant characterization from patient-derived tissues.

    Our laboratory leverages high patient case volumes and an extensive clinical trials network to establish and maintain a large living biobank of patient-derived organoid cultures. These models are used to understand the key drivers that govern system behavior and to explore potential therapeutic approaches. We are currently using high-throughput technologies to characterize clinically-actionable genotype and pharmacotype in efforts to guide precision medicine initiatives. Additional opportunities for academic scholarship include techniques to study molecular biology of epithelial-cancer associated fibroblast interactions, microRNA gene regulation, and immunotherapeutic applications in pancreatic cancer. The laboratory maintains active collaborations with both intramural and extramural researchers as the lead site in translational research stemming from SU2C/Lustgarten foundation funded clinical trial NCT#03563248.

    The fellowship provides an annual salary commiserate with NIH guidelines for PGY level with full healthcare benefits. Postdoctoral scientists will be employees of Johns Hopkins University. Applicants are not required to be United States citizens

    How to apply:

    • Cover letter including a) description of suitability of this position and b) career goals including and following the postdoctoral position.
    • CV including publications, presentations, and other relevant experience.
    • List of referees, with contact info and description of their relationship to the applicant.

    Email application materials to Dr. Richard Burkhart (rburkha6@jhmi.edu)

  • Are you interested in research that is directly influenced by clinically important questions? Chemotherapy-induced peripheral neuropathy (CIPN) is a common dose-limiting side effect of cancer treatment drugs that often presents as debilitating pain; we want to discover new cancer pain therapies using clinically-informed basic science approaches.

    A postdoctoral position is available from August 1, 2021, in the Sivanesan Neuromodulation Laboratory (SNL) / Translational Pain Research Program in the Department of Anesthesiology and Critical Care Medicine at the Johns Hopkins University School of Medicine.

    Dr. Eellan Sivanesan’s lab is embedded in a rich and dynamic scientific "village" encompassing related groups with expertise in somatosensory neuroscience, neuropharmacology, electrophysiology, cancer biology and the tumor microenvironment, and spinal cord stimulation stimulation. The lab is focused on developing new technology to treat cancer pain, cancer-related pain (e.g. chemotherapy-induced peripheral neuropathy), and other chronic pain disorders, and uncovering the neural mechanisms underlying the somatosensory, affective, and cognitive aspects of pain. The position will provide rigorous exposure and mentorship in interdisciplinary pain neuroscience research between the departments of anesthesiology, oncology, and neurological surgery with guidance towards a future career in academia or industry.

    Job description:
    We are seeking an ambitious and motivated postdoctoral candidate who is interested in research into cellular and molecular aspects of sensory physiology and pain. We investigate cancer-related pain conditions (particularly chemotherapy-induced peripheral neuropathy), cancer biology (particularly tumor environment), neuroimmunology, and electrical neuromodulation, and their functions in sensory transduction, conduction, and transmission under both physiological and pathological conditions. We employ multi-disciplinary approaches including immunohistochemistry, immunocytochemistry, molecular biology, light and confocal microscopy, electrophysiology, neuropharmacology, histology, calcium imaging, RNA sequencing, and animal behavioral assessment to conduct pain research. To translate our rodent discoveries, we partner with neurological surgeons, pain medicine physicians / anesthesiologists (invasive neuromodulation experts), and prominent basic scientists to study human neural tissue and human approved neuromodulation devices from patients living with chronic pain.

    We bring together investigators from Departments across Johns Hopkins to collaboratively tackle basic science, translational, and clinical research problems relevant to pain, and operate within a broader multidisciplinary pain research community that includes weekly pain-focused journal clubs, weekly pain seminars, and funding programs to foster the career development of trainees and junior faculty in the pain field. We also benefit greatly from a strong scientific, translational, and clinical research environment at Johns Hopkins that spans numerous biomedical disciplines. Ample opportunities for career development, mentorship and clinical exposure based on candidate interest.

    Key requirements:
    We are looking for a creative and highly motivated postdoctoral researcher with strong enthusiasm for science. A successful candidate should have a PhD degree within the last three years in the biomedical field and a strong academic background in neuroscience, molecular biology, electrophysiology, neurophysiology, pharmacology, cell biology, chronobiology, neuroimmunology, cancer biology (tumor microenvironment), or another related discipline. Applicants should have experience working with animals in a research environment.

    At least one first author publication (peer reviewed original research) and previous experience with pain research are considered strong merits. The ideal candidate should be able to work independently and will take part in experimental planning, applying for grants, drafting of manuscripts and co-supervision of research staff and students. There will be opportunities to develop experimental tasks, analyze large datasets and to present and publish high impact science. Excellent communication skills in English, good interpersonal skills, and ability to work in team environments, and technical and organizational abilities are expected.

    Employment at Johns Hopkins University:
    The employment is a 2-year position with a possibility of prolongation. A 6-month trial period will be applied. Postdoctoral fellow salary will be based on NIH guideline, individual health insurance [through the School of Medicine Student Health Program (SHP)] and dental insurance will be provided. Salary is commensurate with skills and experience and benefits will be provided.

    Apply:
    Interested candidates should submit a single document containing: 1) an updated CV (including date of the thesis defense, title of the thesis, previous academic/work positions, academic title, current position, academic distinctions and list of peer-reviewed publications), 2) a brief personal statement describing research interests and career goals, and 3) contact information for three references. Select applicants will be invited to interview. Please directly email the document to:

    Dr. Eellan Sivanesan, M.D. esivane1@jhmi.edu
    Assistant Professor, Department of Anesthesiology
    Director of Neuromodulation
    Department of Anesthesiology and Critical Care Medicine
    Johns Hopkins University-School of Medicine
    Baltimore, Maryland 21218

    Deadline: January 1, 2022.

    Sivanesan Neuromodulation Laboratory (SNL) Website

    Twitter: @DoctorSivaMD

    LinkedIn: https://www.linkedin.com/in/eellan-sivanesan/

    Johns Hopkins University is an equal opportunity employer M/F/D/V.

  • A postdoctoral position is available for a highly motivated individual to join the Alaish laboratory in the Division of Pediatric Surgery at the Johns Hopkins School of Medicine.

    The Alaish laboratory focuses on the molecular mechanisms underlying short bowel syndrome. The complications of short bowel syndrome including Intestinal barrier loss, cholestasis and intestinal dysbiosis are investigated with the goal to design novel therapies directed at specific sites in the molecular pathways. A major component of this translational research is the use of genetically engineered mice as a model for short bowel syndrome.

    Requirements:

    Candidates should hold a doctorate degree with a background in molecular biology, cell biology, genetics, biochemistry or a related field.

    Candidates with experience in performing surgery on mice are preferred.

    Candidates with a record of research excellence demonstrated by publication will be favored.

    Applicants who are motivated to develop careers as independent investigators are especially encouraged to apply.

    Proficiency in creating tables and figures appropriate for journal publication is required.

    Proficiency in verbal and written English is required.

    Interested candidates should send their CV, a brief letter outlining their future research goals, and names and contact information for at least two references to:

    Samuel M. Alaish, M.D.
    Associate Professor of Surgery
    Surgical Director, THRIVE Pediatric Intestinal Rehabilitation Program
    Division of Pediatric Surgery
    Johns Hopkins School of Medicine
    salaish1@jhmi.edu

  • The Department of Surgery at the Johns Hopkins University School of Medicine is seeking a highly motivated postdoctoral research fellow to join our NIH-funded research group directed by Dr. Hongpeng Jia.

    The research projects of the lab utilize cutting-edge interdisciplinary research approaches and aim to understand how the host response to viral and bacterial lung infection. In particular, The Jia lab will dissect the critical role of, and therapeutic potential for Angiotensin Converting Enzyme 2 (ACE2) in COVID-19 and Influenza viral infection and associated secondary bacterial/viral superinfection. Multiple novel inducible transgenic and gene targeting murine models, genome sequencing analysis, CRISPR gene editing, 3D lung organoid models, and single-cell RNA-seq techniques will be involved in the ongoing research projects

    Candidates should have a PhD and/or MD or equivalent degree, with a strong background in Virology, Immunology, especially Innate immunity and is eligible of working in the united states. The candidates must be enthusiastic toward research projects, and have excellent critical thinking skills, a track-record of productivity as demonstrated by first-author peer-reviewed publications, an ability to work well both independently and as part of a team, and proficiency in written and oral English communication.

    A successful candidate will have the opportunity to lead independent and cutting-edge research projects with a world-class research facility. We will also provide a customizable curriculum, individual career development/support, and Interdisciplinary and collaborative research community.

    Salary will be commensurate with research experience.

    To apply, please send 1) a cover letter with a brief statement of research experience and future proposed interests, 2) contact information of at least 3 references (at least one from former direct mentor) , and 3) a detailed curriculum vitae to: Dr. Hongpeng Jia by email: hjia4@jhmi.edu

    Hongpeng Jia
    Assistant Professor
    Division of Pediatric Surgery
    Department of Surgery
    Johns Hopkins University School of Medicine
    Office: 735A Ross Building
    Tel: 410-955-3429
    Lab: 733 Ross Building
    Tel: 410-614-0568
    1721 E Madison Street
    Baltimore, MD 21205
    Email: hjia4@jhmi.edu

 
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