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Open Postdoctoral Fellowship Positions at SOM-JHU

Below are current postdoctoral fellowship positions that are open at SOM-JHU. For additional details on an open position, contact the primary faculty on the listing.

  • Co-Primary investigators: Chloe Thio, MD and Ashwin Balagopal, MD

    Description of position:
    We are seeking a highly motivated postdoctoral researcher who is interested in applying high resolution molecular techniques to liver tissue samples. The overall goal of this project is to gain insight into hepatitis B transcription at the level of the single hepatocyte before and after anti-HBV therapy. Since HBV transcription is central to HBV replication, such data are needed to advance the HBV cure field. This is a translational project that will apply high-resolution molecular techniques to tissues from HBV-infected people.

    The laboratory is based in the Department of Medicine, Division of Infectious Diseases in the Johns Hopkins University School of Medicine. One of the major goals of the group is to advance knowledge of HBV virology and immunology through translational projects that utilize clinical samples to ask critical questions. Specific projects include 1) utilizing droplet digital PCR (ddPCR) to amplify HBV DNA and RNA from single hepatocytes in people with various stages of hepatitis B and with and without treatment, 2) using RNA seq to probe biological differences between hepatocytes with and without transcriptionally silent cccDNA, 3) role of epigenetics in transcriptional silencing of cccDNA.

    Job Qualifications
    PhD in molecular biology or related field
    Experience/skills in the following areas is desired:

    • Background in hepatitis B or virology
    • Experience with standard molecular techniques, sequencing, and ideally with ddPCR
    • Strong communication and interpersonal skills
    • Fluency in written and spoken English


    Instructions for applying

    To apply please email the following to Dr. Thio (cthio@jhmi.edu) and Dr. Balagopal (abalago1@jhmi.edu)

    • Cover letter describing research interests, career goals, prior experience
    • Curriculum vitae
    • Writing sample (published paper or manuscript draft)
    • Names and contact information of 2-3 references


    Applications will be reviewed on a rolling basis starting March 29th 2021 until the position is filled

  • Primary Faculty: Luigi Adamo, MD Ph.D.

    The Adamo Lab in The Johns Hopkins University Division of Cardiology is seeking a post-doctoral fellow to lead cutting edge research in cardiac-immunology.

    We are looking for a highly motivated and independent researcher with a Ph.D. in immunology, biology, or a related field.

    Candidates must have first-author publications and proven research ability in at least one of the following areas: immunology, models of cardiac injury, cardiac physiology, lymphocyte biology, or aging. Hands-on experience in translational animal models is also required.

    Experience in the following techniques is helpful but not required: flow cytometry, immunohistochemistry, and immunofluorescence.

    A successful candidate will have a strong work ethic, strong organizational skills, excellent critical thinking abilities, excellent ability to work as part of a team and a desire to push the boundaries of existing knowledge. The postdoctoral researcher will work under supervision but will be expected to lead methods development, lead manuscript and grant writing efforts, conduct independent research and supervise junior researchers.

    We offer multifaceted scientific projects, strong scientific collaborations, and attentive mentoring in the context of the vibrant, word class research environment of Johns Hopkins University. We are passionate about discovery and drug development. If you share our passion and fit the above description, we would love to hear from you.

    Adamo Cardiac-Imunology Lab
    ladamo2@jhmi.edu
    http://hopkinsmedicine.org/adamo-lab

  • Job Title: Research Fellow
    Working Title: Research Fellow
    Job Family: Research
    FLSA: Exempt

    Department: Oncology (Cancer Epigenetics and Therapeutic Resistance)

    Reports to: Principal Investigators: Drs. Eneda Toska and Elana Fertig

    The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University is recruiting an individual to lead analyses on epigenomics analyses such as (ChIP-seq, ATAC-seq and RNA-seq) and single cell analyses in cancer models. This person will be active in the data pre-processing stages as well as analysis and interpretation of results.

    The Toska lab integrates biochemistry, cell signaling, genomics and epigenomics at bulk and single cell level to study the fundamental processes by which epigenetic regulators regulate transcription, have the ability to drive tumorigenesis and dictate therapeutic response in breast cancer. The Fertig lab develops time course models of therapeutic resistance and performs single cell technology development. Her computational methods are used to determine the molecular mechanisms of therapeutic resistance from multi-platform genomics and epigenomics data. The successful candidate will become a fundamental component of this multidisciplinary team with mentorship in both computational and biological processes affecting therapeutic response in cancer.

    Eligible candidate will be involved in designing and developing analysis plans to address biological hypotheses in our ChIP-seq/ATAC-seq/RNA-seq and RNA-seq and ATAC-seq at the single level acquired from breast cancer models such as cell lines, organoids, and patients treated with targeted therapies. The candidate will interact daily with other data analysts within the Institute, as well as Genomics experts, and clinicians. This position requires collaboration with clinical and scientific investigators in research/study design, data analysis plans, algorithm development, grant applications, and preparation of presentations and publications. The candidate should work independently and in collaboration with faculty to solve problems posed by the clinical and laboratory investigators along the study design, data generation, collection and management process; interaction with bioinformatic experts, biostatistician program developers, computational scientists, health informatic experts as well as postdoc fellows from the Sidney Kimmel Comprehensive Cancer Center and the Bloomberg School of Public Health on our epigenomic data mining initiatives with the goal of translating these findings into therapeutic modalities for cancer patients. The applicant may share efforts between 1-3 labs.

    DUTIES AND RESPONSIBILITIES

    • Plan data management including determining type, format of data and types of documentation, considering privacy, confidentiality and other ethical issues
    • Facilitate acquisition of single cell sequencing data from core facilities
    • Clean data by coding missing data, fixing or deleting miscoded data, transforming variables into more useful formats, and annotating the data in proper way, use descriptive statistics to help characterize and summarize the data
    • Collaborate with clinical and scientific investigators in the breast cancer and biostat teams to propose ideas for new projects, design research, develop data plan, and prepare analyses with general direction from investigators
    • Apply different technical approaches to visualize the data and prepare publication-quality tables and graphs based on valid analysis
    • Lead or participate actively in the team responsible for designing and validating analysis data sets, programs, and statistical output products
    • Identify potential data problems from analytic queries and bring them to the attention of the team.
    • Demonstrate understanding of high dimensional data collection processes and data sets and share knowledge with collaborators.
    • Collaborate closely with investigators, and other team leadership to ensure that research study or project results and conclusions are presented accurately and without bias.
    • Demonstrate progress in ability to multi-task and manage time spent working with individual faculty members and on specific projects.
    • Participates in regularly schedule meetings with study investigators and team. Prepares progress reports as needed. Maintain appropriate systems for data organization.
    • Assure data quality for documentation and dissemination of data. Conduct and track specific activities to accomplish project goals, including evaluating and reporting data and documenting analytic procedures.
    • Able to work collaboratively in a team environment with a high degree of initiative and self-motivation.


    Supervision of Others:

    NA


    Equipment, Machine, or Tool Requirements:

    • Experience with computers and servers and knowledge of Linux/UNIX as well as other common operating systems such as Mac OS and Windows is necessary.
    • Experience with server configuration and troubleshooting preferred.
    • Ability to use the internet and web-based scholarly search engines.


    REQUIREMENTS

    Minimum Qualifications:

    Education:

    Required: Bachelor’s Degree in Statistics, Computer Science Bioinformatics and PhD in Statistics, Computer Science Bioinformatics or related field

    Experience:

    • Minimum of 3-4 years related experience in analyzing genomic data
    • Experience with code development, optimization, and testing


    Licensure, Certification, Registration:

    NA


    Special Knowledge, Skills, or Abilities / Competencies:

    • Proficiency with bioinformatics concepts, methods, and tools, with experience working in languages such as R or Python, leveraging Bioconductor and bioconda.
    • Coursework or work experience covering topics in statistics, molecular biology, genetics, and script-level programming.
    • Proficiency with genomic data, tools, and databases.
    • Familiarity with common computational biology tools.
    • Experience with experimental design principles, reproducible research principles,
    • and data storage, security, and safety.
    • Excellent interpersonal skills in consulting with researchers and understanding
    • their problems.
    • Excellent writing and verbal skills in the preparation and presentation of reports.
    • Excellent organizational skills and attention to details are required.
    • Must be detail-oriented, focused, creative, and independent
    • Proficiency in both written and spoken English with excellent communication


    Skills

    • Familiarity with common computational biology tools and software packages, such as Bioconductor
    • Familiarity with cancer epigenetics is preferred


    Contact Information:
    Dr. Eneda Toska

    etoska1@jhmi.edu

     

  • The Department of Anesthesiology and Critical Care Medicine (ACCM) and the Armstrong Institute Center for Health Care Human Factors (www.hopkinsmedicine.org/armstrong/humanfactors) at the Johns Hopkins University School of Medicine is recruiting a postdoc research fellow and/or a research coordinator.

    The ideal applicant will have experience in human factors engineering, cognitive systems engineering, human computer interaction, human factors psychology, or a related field. Experience in health care related work is highly desired, though not required. Experience or interest in both qualitative and quantitative analysis methods is also desired.

    The fellow will primarily be working with James H Abernathy, III, MD, MPH along with Ayse Gurses, PhD and other research team members on one or more funded research projects in the areas of human factors in patient safety and/ or health informatics. The individual will also have the opportunity to collaborate with other interdisciplinary research members of ACCM and the Armstrong Institute for Patient Safety and Quality.

    Primary Responsibilities:

    • Work collaboratively with study team on federally funded patient safety and human factors engineering-based research projects
    • Manage and perform data collection activities
    • Assist in the analysis and management of data (both qualitative and quantitative data analysis)
    • Assist in the preparation of study protocols and materials (e.g., IRB) and other essential functions
    • Conduct literature reviews and summarize findings
    • Author/co-author research manuscripts
    • Help with writing grant proposals, lead writing career grants (if interested and applicable)
       

    Education:

    • PhD or Master’s level degree or equivalent is required. Individuals with clinical backgrounds with interest in research will also be considered.
       

    Experience & Required Skills:

    • An individual with formal training and experience in human factors, cognitive systems engineering, human computer interaction, macroergonomics, sociotechnical systems design, or a related field.
    • An in-depth understanding of human cognition and usability design principles as they pertain to the design of technology to support and facilitate work (individual work and teamwork)
    • Knowledge of sociotechnical system approaches to research and design; an understanding of work system redesign to improve processes and outcomes.
    • Good understanding of related research processes and methodologies including qualitative and quantitative research methods.
    • Experience with knowledge elicitation methods (e.g., interviews, focus groups, and contextual inquiry), data driven design, iterative design processes, user-centered design, prototyping, and usability evaluations
    • Strong interest in conducting field research in health care environments
    • Ability to work independently as well as collaboratively as part of a research team
    • Ability to balance and prioritize tasks, and delivers timely outcomes
    • Excellent problem solving, organizational, writing and communication skills
       

    Nice to Have:

    • Knowledge/experience in ecological interface design and related design philosophies
    • Experience with prototyping methods and prototyping software (Adobe Creative Suite, PowerPoint, Balsamiq etc.)
    • Knowledge/experience with software/coding languages appropriate for the development of interfaces/ health IT
    • Experience with conducting usability evaluations (formative and summative)
    • Experience in research processes and qualitative methodologies for data collection & analysis, with corresponding software experience (e.g. semi-structured interviews, and thematic analysis with NVivo)
    • Familiarity with quantitative analysis methods and corresponding software experience (e.g., statistical analysis with SPSS)
    • Familiarity with the healthcare domain and experience conducting research in healthcare.
    • Experience in IRB protocol preparation
       

    Application deadline:

    • No specific deadline. However, applicants are encouraged to apply for the position as soon as possible. This position has an immediate starting date.
    • Apply now by sending applications to Carol Stokeling at cstokel1@jhmi.edu
    • Please provide a cover letter, CV, names and contact information of three references, and a personal statement (600 words max).
  • The newly established Ruan Lab at The Johns Hopkins All Children's Hospital’s Institute for Fundamental Biomedical Research (IFBR) is recruiting two postdoctoral research fellows to study RNA metabolism in the context of health and diseases begin in July 2021.

    By taking advantage of a unique humanized liver mouse model, the Ruan Lab's research focuses on studying how RNA metabolism in human responses to nutrients and stress at the organism level and how dysregulation of these processes causes diseases and aging. The current research projects include:

    (1) Study the molecular mechanisms controlling the activity of our recently identified human lncRNAs associated with cardiometabolic traits.
    (2) Reveal how RNA degradation machinery, especially the 5' RNA degradation pathway, is regulated by overnutrition and explore its role in fatty liver diseases.
    (3) Identify nuclear-enriched lncRNAs that regulate pre-mRNA splicing in the liver and brain and explore their roles in aging.

    The Ruan lab is devoted to foster the career success of postdoctoral research fellows. By joining IFBR, the fellows' research will benefit from active collaboration with experts from the institute's Center for Metabolic Origins of Disease and Center for RNA Biology and the rich resource of Johns Hopkins school of medicine. Salary will follow the NIH standard. Located in St. Petersburg, Florida, IFBR will provide fellows a great work/life environment that Tampa Bay can offer.

    Successful candidates are expected to hold a Ph.D., M.D., or M.D./Ph.D. degree by July 2021. Previous research experience in RNA biology, animal experiments, and analysis of RNA-seq data is a plus. Please submit your application package, including a cover letter, CV, and contact information of at least three referees to Lorenzo Thomas at lthoma82@jhmi.edu.

  • The Trapecar Lab at the Johns Hopkins All Children’s Hospital and Institute for Fundamental Biomedical Research in St. Petersburg, Florida, is looking to hire two postdoctoral scientists.

    The focus of the group is the exploration of fundamental origins of immunometabolic diseases, such as IBD, metabolic syndrome and neurodegenerative disorders, by using exciting, multiorgan human-on-a-chip technologies and systems biology. To get a sense of the approach please consult www.trapecarlab.org and see two recent papers: Trapecar et al., Cell Systems 2020 and Trapecar et al., Science Advances, 2021.

    An ideal candidate will have strong conceptual and practical experience in two or more of the following areas: immunology, stem cell biology, molecular biology and tissue engineering. Types of tissues and organs that the lab is particularly interested in are mucosal tissue like intestine and lungs, liver, neuronal and adipose tissue as well as a wide range of circulating and tissue-resident immune cells. Common techniques used in the lab are cell culturing (primary cells, organoids, iPS cells), flow cytometry and cell sorting, generation and analysis of transcriptomic as well as metabolomic data (Chipseq, scRNAseq…), confocal microscopy, multiplexed cytokine/chemokine analysis (ELISAs, Luminex) and use of bioengineered tools like human-on-a-chip platforms to study human multiorgan interactions.

    Successful candidates must be capable to work in highly multidisciplinary research teams and have a demonstrated track record of success in independent scientific research. Strong applicants will exhibit significant basic science understanding, scientific rigor, motivation, and an ability to originate, carry out, and publish significant original research in collaboration with their JHU mentors. Strong written and verbal English language skills are required.

    The rapidly growing new Institute for Fundamental Biomedical Research is part of the Johns Hopkins All Children’s Hospital in St. Petersburg, Florida, and the Johns Hopkins University (JHU) School of Medicine ecosystem. It represents a superbly equipped research environment that aims to connect basic and clinical researchers to solve some of the biggest medical challenges. Trainees and postdoctoral scientists have also full access to resources available at the main JHU Baltimore campus and are strongly encouraged to participate in JHU-wide activities and collaborations. The lab and institute are fully committed to the candidate’s career development and path to independence.

    St. Petersburg offers a great quality of life in terms of affordability, pristine nature, close proximity to Tampa bay’s international airport, and vibrant cultural life.

    If interested in the position, please submit a CV and brief description of scientific interests to mtrapec1@jhmi.edu.

  • Job Description. The Computational Cardiology Lab (PI: Natalia Trayanova, trayanovalab.org) at the Department of Biomedical Engineering and the Alliance for Cardiovascular Diagnostic Innovation (heartadvance.jhu.edu), Johns Hopkins University, seeks computational cardiac electrophysiology postdoctoral fellows or research scientists. Multiple positions are available. The Lab is developing and translating to the clinic personalized computational digital-twin technologies and machine learning approaches for the prognosis and treatment of heart rhythm disorders. Our work focuses on using computational heart modeling to predict risk of sudden cardiac death or other adverse cardiac outcomes. We design personalized treatment interventions for atrial fibrillation and ventricular arrhythmias based on computational modeling with the goal to maximize clinical procedure success and minimize the arrhythmia recurrence and re-hospitalization. We are currently involved in a clinical trial testing the utility of cardiac modeling in ablation targeting for persistent atrial fibrillation. We also conduct research exploring the mechanisms for arrhythmias. The Postdoctoral Scholars/ Research Scientists will perform research on NIH-funded translational projects.

    Job Requirements. Candidates must hold a PhD in biomedical engineering/bioengineering, applied math, physics, biophysics, or closely related fields and must have lead-author publication(s) in computational modeling of the heart. Candidates should also have strong communication skills and the ability to work both independently and as part of a collaborative team. Prior experience in cardiac modeling and programming skills is a must.

    Job Information. To apply, please send a CV, cover letter, and contact information for three references to Melissa Foley-King at mfoleyk1@jhu.edu. Inquiries can be directed at Dr. Natalia Trayanova, ntrayanova@jhu.edu. The positions will remain open until filled. Salary depends on experience.

  • This fellowship will equip a performing arts medicine clinician or performance science professional with a comprehensive skill set in preparation for leadership of a department/division within an academic institution, performing arts company, professional organization, or similar group.

    The Post-Doctoral Fellow in Performing Arts Health, Science and Education reports to and is supported by a team of faculty and staff from the Peabody Institute and Johns Hopkins Medicine’s Department of Physical Medicine and Rehabilitation. The Fellow’s research activity will be mentored by Dr. Preeti Raghavan, while education and administrative responsibilities will be overseen by staff from Peabody’s JHRN clinic, student affairs department, and the office of the Associate Dean for Innovation, Interdisciplinary Partnerships & Community Initiatives. This is a 12-month renewable fellowship.

    Activities within the following Programmatic Pillars will be tailored to the Fellow’s clinical expertise, professional background, and future career interests:

    1. Education (clinical, performing arts pedagogy, community, prevention, health awareness)
    2. Preventative Health Strategies (musculoskeletal, mindset/mental health, nutrition, fitness)
    3. Systems Navigation (academic, healthcare, industry, professional organizations, community)
    4. Administration (leadership and operations management)
    5. Investigation (injury surveillance, population health, clinical practice/outcomes, value-based care, performance physiology, biomechanics)
    6. Advocacy & Policy (industry and professional advocacy, health policy, occupational health, government policy)

    Successful candidates will hold a PhD, terminal degree, or clinical doctorate in PT, OT, SLP, MD, DO, DC, Psychology, Nutrition, Psychology, Applied Physiology, Biomechanics/Kinesiology, Public Health, Education. Preference will be given to candidates with a demonstrated commitment to and/or proficiency/accomplishment in the performing arts, as well as experience with curriculum design and teaching in higher ed and/or community context. Please see further details and submit your application package at apply.interfolio.com/86281 including a cover letter, C.V., and a research or curriculum/teaching sample. For questions regarding the position, please contact sarah.hoover@jhu.edu.

  • Job Description:
    The Johns Hopkins University Department of Dermatology Cutaneous Oncology Fellowship Program offers a unique clinical and research experience across the disciplines of cutaneous oncology including cutaneous lymphoma, melanoma, skin cancer in high risk/ immunocompromised (solid organ transplant patients) and supportive oncodermatology. Fellows will work with our expert clinicians and physician scientists, to gain skills in clinical and translational research. The clinical fellows are expected to productively participate in the clinical and translational research activities of the Department of Dermatology, publish scholarly clinical research articles during their fellowship and make at least one scientific presentation. Fellows will assist in developing protocols for clinical research studies, work with the Institutional Review Board (IRB), recruit study patients, conduct study visits, and learn/ improve data management skills. Fellows will also interact with pathology, oncology and transplant teams in multidisciplinary patient care. They will work with basic scientists on translational research projects. Fellows will have the opportunity for organizational leadership role in organizing local cutaneous oncology meetings.

    Requirements
    Position open to:

    • 3rd to 5th year medical student or
    • MD or MD/PhD degree and completion of at least 1 year PGY1 residency (by June 30) or
    • Fellows may also have already completed dermatology residency

    Updated CV and 3 references
    All available USMLE transcripts (e.g., Steps 1, 2 CK, 2 CS and 3)
    Maryland State Medical License; at the time of the beginning of the fellowship (July 1), if applicable
    Preference will be given to those who have completed a residency in internal medicine or dermatology and have an interest in an academic career.
    Interested applicants should send a brief statement of their interests and career goals with the aforementioned items

    Dates
    This is a one to two-year fellowship upon mutual agreement. Each appointed term runs from July 1st through June 30th, or upon agreement.

    Contact:
    Courtney C. Elcock
    Sr. Administrative and Development Coordinator
    (410)955-8662
    (410)955-8645(fax)
    celcock1@jhmi.edu

  • Primary Faculty: Darrell J. Gaskin, Ph.D.

    This announcement is for a postdoctoral fellowship in the Training in Orthopedic Team Science (TOTS) program at the Bloomberg School of Public Health at Johns Hopkins University. The postdoctoral fellow will work with a multidisciplinary team from the Bloomberg School of Public Health and the Department of Orthopedic Surgery in the School of Medicine. This multidisciplinary team will investigate the economic implications of issues of diversity within the field of orthopedics for patients and providers. This team will consist of the postdoctoral fellow, an orthopedic surgery resident physician trainee, a clinical mentor and research mentor.

    This position is funded by a T32 grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health. This postdoctoral position has a two-year training period. The postdoctoral fellow will work in partnership with an orthopedic surgery resident physician trainee to apply experimental research methods in economics to musculoskeletal healthcare disparities. One of the goals of this program is for the resident and the postdoctoral fellow to develop complementary projects on disparities in musculoskeletal healthcare.

    The postdoctoral fellow will be mentored by Darrell J. Gaskin, PhD, Director of the Johns Hopkins Center for Health Disparities Solutions and the William C. and Nancy F. Richardson Professor in Health Policy. The TOTS team will include an orthopedic surgery resident physician trainee and their clinical mentor from the Department of Orthopedic Surgery. This is an in-person position; however, while COVID pandemic protocols are in place, the postdoctoral fellow will be expected to work from home.

    Only U.S. citizens, non-citizen nationals, or those lawfully admitted for permanent residence are eligible for this position.
    Qualified applicants for the postdoctoral fellowship should have the following:

    1) A Ph.D. in Economics, Health Economics, Epidemiology, or related field. (It is possible to apply for the position if one expects to achieve a doctoral degree by June 30, 2021).
    2) Ability to conduct independent economic research, apply experimental methods to healthcare economics, and assume responsibility for the development and completion of research papers.
    3) Demonstrated ability to work as part of a research team on collaborative projects with successful completion of project aims and deadlines.

    Applications will be considered on a rolling basis until the position is filled. Please submit applications via email to Dr. Darrell J. Gaskin at HCHDS@jhu.edu.

    Completed applications should include:
    1) A 2-page research statement describing one’s research interests and how they relate to disparities in musculoskeletal healthcare.
    2) A current CV.
    3) A job market paper.
    4) A letter of support from one’s dissertation advisor or a member of their dissertation committee.
    5) Two letters of recommendation.

  • A postdoctoral fellow position is currently open in Dr. Rui Zhou’s laboratory in the Departments of Medicine, Biological Chemistry and Oncology, Johns Hopkins University School of Medicine and Center for RNA Biology, Johns Hopkins All Children’s Hospital. The Zhou laboratory is employing a combination of biochemical, genetic, genomic and functional genomic approaches to study the molecular mechanism governing the biogenesis of regulatory non-coding RNAs, and to elucidate their function in innate immunity, neuro-development, metabolism and tumor formation.

    We have identified and characterized key regulators of RNA interference and antiviral defense (Zhou et al, Molecular Cell, 2008; Sabin, Zhou et al, Cell, 2009; Czech & Zhou et al, Molecular Cell, 2009; Ni, Zhou & Czech et al, Nature Methods, 2011; Xiong et al, PNAS, 2013; Lim et al, RNA Biology, 2014; Xiong et al, PLoS Genetics, 2015; Molleston et al, Genes & Development, 2016). In addition, we have established microRNA-34 as a crucial modulator of innate immunity and steroid hormone signaling (Xiong et al, PLoS Pathogens, 2016). Furthermore, we have identified a group of circular RNAs that impact innate immunity and neuro-development (Xiong et al, submitted; Liu et al, in preparation). Moreover, we are investigating the function and regulation of circular RNAs in lipid metabolism and antiviral immunity. Ongoing work focuses on elucidating the underlying molecular mechanism using both animal models and cultured cells. We seek a postdoctoral fellow to drive these exciting projects forward.

    Required skills: The successful candidate must have a strong background in at least one of the following areas: biochemistry, molecular biology, and genetics, and should be highly motivated, and superb at both bench work and critical thinking.

    This position is expected to start immediately, and will be based at the Center for RNA Biology, Johns Hopkins All Children’s Hospital in St. Petersburg, Florida, which is known for its pleasant weather, low cost of living, and beautiful beaches. Salary and fringe benefits will be compliant with guidelines established by the Johns Hopkins University School of Medicine. The Zhou Lab is located in the newly completed 225,000-square-foot state-of-the-art Research & Education Building. We enjoy interactions with a vibrant and collegial group of Departmental colleagues working on RNA Biology, gene regulation, vascular biology, immunology, oncology and metabolism. Interested candidates please send CV and relevant publications to Dr. Rui Zhou: rzhou13@jhmi.edu.

  • General Description
    We are seeking recent Ph.D. graduates to join a postdoctoral fellowship program developing approaches to clinically relevant molecular characterization of patient-derived three dimensional models of pancreatic cancer. The fellowship program is jointly advised by faculty from the Department of Surgery and Oncology as part of the Pancreatic Cancer Multidisciplinary Laboratory and the Pancreatic Cancer Precision Medicine Center of Excellence at Johns Hopkins Hospital and Johns Hopkins Medical Institutions. This unique opportunity will allow postdoctoral fellows to gain academic research experience with direct translational relevance and implementation of patient-centered clinical research projects. Successful candidates will have an interest in improving techniques in rapid tumor modeling and clinically-relevant characterization from patient-derived tissues.

    Our laboratory leverages high patient case volumes and an extensive clinical trials network to establish and maintain a large living biobank of patient-derived organoid cultures. These models are used to understand the key drivers that govern system behavior and to explore potential therapeutic approaches. We are currently using high-throughput technologies to characterize clinically-actionable genotype and pharmacotype in efforts to guide precision medicine initiatives. Additional opportunities for academic scholarship include techniques to study molecular biology of epithelial-cancer associated fibroblast interactions, microRNA gene regulation, and immunotherapeutic applications in pancreatic cancer. The laboratory maintains active collaborations with both intramural and extramural researchers as the lead site in translational research stemming from SU2C/Lustgarten foundation funded clinical trial NCT#03563248.

    The fellowship provides an annual salary commiserate with NIH guidelines for PGY level with full healthcare benefits. Postdoctoral scientists will be employees of Johns Hopkins University. Applicants are not required to be United States citizens

    How to apply:

    • Cover letter including a) description of suitability of this position and b) career goals including and following the postdoctoral position.
    • CV including publications, presentations, and other relevant experience.
    • List of referees, with contact info and description of their relationship to the applicant.

    Email application materials to Dr. Richard Burkhart (rburkha6@jhmi.edu)

  • Are you interested in research that is directly influenced by clinically important questions? Chemotherapy-induced peripheral neuropathy (CIPN) is a common dose-limiting side effect of cancer treatment drugs that often presents as debilitating pain; we want to discover new cancer pain therapies using clinically-informed basic science approaches.

    A postdoctoral position is available from October 1, 2021, in the Sivanesan Neuromodulation Laboratory (SNL) / Translational Pain Research Program in the Department of Anesthesiology and Critical Care Medicine at the Johns Hopkins University School of Medicine.

    Dr. Eellan Sivanesan’s lab is embedded in a rich and dynamic scientific "village" encompassing related groups with expertise in somatosensory neuroscience, neuropharmacology, electrophysiology, cancer biology and the tumor microenvironment, and spinal cord stimulation stimulation. The lab is focused on developing new technology to treat cancer pain, cancer-related pain (e.g. chemotherapy-induced peripheral neuropathy), and other chronic pain disorders, and uncovering the neural mechanisms underlying the somatosensory, affective, and cognitive aspects of pain. The position will provide rigorous exposure and mentorship in interdisciplinary pain neuroscience research between the departments of anesthesiology, oncology, and neurological surgery with guidance towards a future career in academia or industry.

    Job description:
    We are seeking an ambitious and motivated postdoctoral candidate who is interested in research into cellular and molecular aspects of sensory physiology and pain. We investigate cancer-related pain conditions (particularly chemotherapy-induced peripheral neuropathy), cancer biology (particularly tumor environment), neuroimmunology, and electrical neuromodulation, and their functions in sensory transduction, conduction, and transmission under both physiological and pathological conditions. We employ multi-disciplinary approaches including immunohistochemistry, immunocytochemistry, molecular biology, light and confocal microscopy, electrophysiology, neuropharmacology, histology, calcium imaging, RNA sequencing, and animal behavioral assessment to conduct pain research. To translate our rodent discoveries, we partner with neurological surgeons, pain medicine physicians / anesthesiologists (invasive neuromodulation experts), and prominent basic scientists to study human neural tissue and human approved neuromodulation devices from patients living with chronic pain.

    We bring together investigators from Departments across Johns Hopkins to collaboratively tackle basic science, translational, and clinical research problems relevant to pain, and operate within a broader multidisciplinary pain research community that includes weekly pain-focused journal clubs, weekly pain seminars, and funding programs to foster the career development of trainees and junior faculty in the pain field. We also benefit greatly from a strong scientific, translational, and clinical research environment at Johns Hopkins that spans numerous biomedical disciplines. Ample opportunities for career development, mentorship and clinical exposure based on candidate interest.

    Key requirements:
    We are looking for a creative and highly motivated postdoctoral researcher with strong enthusiasm for science. A successful candidate should have a PhD degree within the last three years in the biomedical field and a strong academic background in neuroscience, molecular biology, electrophysiology, neurophysiology, pharmacology, cell biology, chronobiology, neuroimmunology, cancer biology (tumor microenvironment), or another related discipline. Applicants should have experience working with animals in a research environment.

    At least one first author publication (peer reviewed original research) and previous experience with pain research are considered strong merits. The ideal candidate should be able to work independently and will take part in experimental planning, applying for grants, drafting of manuscripts and co-supervision of research staff and students. There will be opportunities to develop experimental tasks, analyze large datasets and to present and publish high impact science. Excellent communication skills in English, good interpersonal skills, and ability to work in team environments, and technical and organizational abilities are expected.

    Employment at Johns Hopkins University:
    The employment is a 2-year position with a possibility of prolongation. A 6-month trial period will be applied. Postdoctoral fellow salary will be based on NIH guideline, individual health insurance [through the School of Medicine Student Health Program (SHP)] and dental insurance will be provided. Salary is commensurate with skills and experience and benefits will be provided.

    Apply:
    Interested candidates should submit a single document containing: 1) an updated CV (including date of the thesis defense, title of the thesis, previous academic/work positions, academic title, current position, academic distinctions and list of peer-reviewed publications), 2) a brief personal statement describing research interests and career goals, and 3) contact information for three references. Select applicants will be invited to interview. Please directly email the document to:

    Dr. Eellan Sivanesan, M.D. esivane1@jhmi.edu
    Assistant Professor, Department of Anesthesiology
    Director of Neuromodulation
    Department of Anesthesiology and Critical Care Medicine
    Johns Hopkins University-School of Medicine
    Baltimore, Maryland 21218

    Deadline: January 1, 2022.

    Sivanesan Neuromodulation Laboratory (SNL) Website

    Twitter: @DoctorSivaMD

    LinkedIn: https://www.linkedin.com/in/eellan-sivanesan/

    Johns Hopkins University is an equal opportunity employer M/F/D/V.

  • A postdoctoral position is available for a highly motivated individual to join the Alaish laboratory in the Division of Pediatric Surgery at the Johns Hopkins School of Medicine.

    The Alaish laboratory focuses on the molecular mechanisms underlying short bowel syndrome. The complications of short bowel syndrome including Intestinal barrier loss, cholestasis and intestinal dysbiosis are investigated with the goal to design novel therapies directed at specific sites in the molecular pathways. A major component of this translational research is the use of genetically engineered mice as a model for short bowel syndrome.

    Requirements:

    Candidates should hold a doctorate degree with a background in molecular biology, cell biology, genetics, biochemistry or a related field.

    Candidates with experience in performing surgery on mice are preferred.

    Candidates with a record of research excellence demonstrated by publication will be favored.

    Applicants who are motivated to develop careers as independent investigators are especially encouraged to apply.

    Proficiency in creating tables and figures appropriate for journal publication is required.

    Proficiency in verbal and written English is required.

    Interested candidates should send their CV, a brief letter outlining their future research goals, and names and contact information for at least two references to:

    Samuel M. Alaish, M.D.
    Associate Professor of Surgery
    Surgical Director, THRIVE Pediatric Intestinal Rehabilitation Program
    Division of Pediatric Surgery
    Johns Hopkins School of Medicine
    salaish1@jhmi.edu

  • The Department of Surgery at the Johns Hopkins University School of Medicine is seeking a highly motivated postdoctoral research fellow to join our NIH-funded research group directed by Dr. Hongpeng Jia.

    The research projects of the lab utilize cutting-edge interdisciplinary research approaches and aim to understand how the host response to viral and bacterial lung infection. In particular, The Jia lab will dissect the critical role of, and therapeutic potential for Angiotensin Converting Enzyme 2 (ACE2) in COVID-19 and Influenza viral infection and associated secondary bacterial/viral superinfection. Multiple novel inducible transgenic and gene targeting murine models, genome sequencing analysis, CRISPR gene editing, 3D lung organoid models, and single-cell RNA-seq techniques will be involved in the ongoing research projects

    Candidates should have a PhD and/or MD or equivalent degree, with a strong background in Virology, Immunology, especially Innate immunity and is eligible of working in the united states. The candidates must be enthusiastic toward research projects, and have excellent critical thinking skills, a track-record of productivity as demonstrated by first-author peer-reviewed publications, an ability to work well both independently and as part of a team, and proficiency in written and oral English communication.

    A successful candidate will have the opportunity to lead independent and cutting-edge research projects with a world-class research facility. We will also provide a customizable curriculum, individual career development/support, and Interdisciplinary and collaborative research community.

    Salary will be commensurate with research experience.

    To apply, please send 1) a cover letter with a brief statement of research experience and future proposed interests, 2) contact information of at least 3 references (at least one from former direct mentor) , and 3) a detailed curriculum vitae to: Dr. Hongpeng Jia by email: hjia4@jhmi.edu

    Hongpeng Jia
    Assistant Professor
    Division of Pediatric Surgery
    Department of Surgery
    Johns Hopkins University School of Medicine
    Office: 735A Ross Building
    Tel: 410-955-3429
    Lab: 733 Ross Building
    Tel: 410-614-0568
    1721 E Madison Street
    Baltimore, MD 21205
    Email: hjia4@jhmi.edu

  • The Hopkins Eye & Brain Tumor Laboratory led by investigators Charles Eberhart, Eric Raabe, and Jeffrey Rubens is seeking a highly motivated Post-Doctoral Scholar to lead translational pediatric neuro-oncology research, advancing novel therapies to improve the lives of children suffering from brain tumors. Research will focus on identifying metabolic vulnerabilities in the infantile brain tumor, atypical teratoid/rhabdoid tumor and determining the efficacy and epigenetic consequences of precise metabolic inhibitors of these pathways. This research will help the post-doctoral scholar develop a unique niche in cancer research at the cross-section of drug development, cancer metabolomics, and epigenetics. The post-doc will process and analyze metabolomics data, plan and analyze DNA methylation studies, and test the in vitro and in vivo efficacy of novel therapeutics in patient-derived cell models and mouse xenografts of pediatric brain tumors. Funding is established for this position with an associated research budget. Post-docs will be encouraged to attend and present at national and international scientific meetings each year and funds exist for training courses such as “Hands on Metabolomics Workshop” at UC Davis or Columbia’s Epigenetic Boot Camp. Position is for 2 years with opportunities for further extensions.

    Essential Qualifications:

    • Ph.D. in biology, chemistry or related fields


    Preferred Qualifications:

    • Proficiency in epigenomics and bioinformatics
    • Proficiency in metabolomics
    • Experience working with RNA, DNA, proteins and/or other biomolecules


    Application process: Applicants should submit an application packet that includes a cover letter, CV, (including contact information for three references) and 1-3 relevant publications - emailed to Jeffrey Rubens at jrubens6@jhmi.edu

  • Two postdoctoral fellow positions are open in the laboratory of Dr. Jianhua Xiong at the Johns Hopkins University School of Medicine/Johns Hopkins All Children’s Hospital in St. Petersburg, Florida. The long-term goal of Dr. Xiong’s laboratory is to identify novel molecular and cellular targets that can be harnessed for cell therapy, immunotherapy and drug discovery against metabolic, cardiovascular and inflammatory diseases. Dr. Xiong is an awardee of the National Institutes of Health (NIH)/National Heart, Lung, and Blood Institute (NHLBI) R00 equivalent grant. He completed his NIH postdoc training in the laboratories led by Dr. Finkel (U.S. National Academy of Medicine member) and Dr. Leonard (Director, Immunology Center; U.S. National Academy of Sciences member) at NHLBI.

    Located in the beautiful Tampa Bay area, Dr. Xiong’s laboratory utilizes systems cell biology and immunology approaches to study the metabolic and cytokine-mediated regulation of cell fate and function in the vascular and immune systems, ranging from basic molecular mechanisms to human disease. Relevant publications include: Xiong J et al. T-cell related manuscript for submission; Xiong J et al. Molecular Cell 2018 PMID: 29429925 (Editorially highlighted in Nat. Rev. Mol. Cell Biol., Trends. Mol. Med. and Trends Endocrinol. Metab.); Xiong J. Trends Endocrinol. Metab. 2018 PMID: 30314937; Xiong J. Trends Biochem. Sci. 2018 PMID: 29735398; Xiong J et al. J. Cell Biol. 2015 PMID: 25733712 (Editorially highlighted in Nat. Rev. Mol. Cell Biol. and J. Cell Biol.); Xiong J et al. Oncogene 2010 PMID: 20562918.

    Requirements: One position is focused on metabolic regulation of T cell differentiation and function; the other position is focused on endothelial cell function, metabolism and vascular-immune crosstalk. We are fully committed to the postdoc career development. Postdocs have full access to research resources from JHU Baltimore and Florida campuses.

    • Possess or be on track to complete a Ph.D., M.D., or equivalent doctoral degree in immunology, cell biology, biochemistry, molecular biology, genetics, or a related field.
    • Comfortable working with mice and/or patient samples.
    • Experience with T cell or endothelial cell culture and analyses is preferred.
    • Experience with histopathology, super-resolution confocal microscopy, next-generation sequencing, or mass spectrometry-based proteomic and metabolomic approaches is a plus but not required.
       

    Qualified candidates, particularly with prior training in immunology or cell biology, are welcome to send their CV, cover letter or research statement, and contact information of three referees in a single PDF file, to Dr. Jianhua Xiong, by email at jxiong10@jhmi.edu with subject “Postdoc application + Your name”.

  • A postdoctoral position is available in the Braunstein laboratory in the Division of Hematology at the Johns Hopkins School of Medicine in Baltimore, MD. We are seeking a creative and highly motivated postdoctoral researcher to join our team and lead the efforts to uncover and characterize the genetic mechanisms driving pathogenesis of complement mediated hematologic diseases.

    Prior research in the Braunstein Lab has identified a role for complement in the pathogenesis of multiple disorders including catastrophic antiphospholipid antibody syndrome (CAPS) and hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome of pregnancy. Available research projects focus on the study of complement gene variants in these and related thrombotic microangiopathies. This research will characterize new disease genes and pathways, develop molecular techniques to study disease mechanisms, and perform clinical assessment of disease phenotypes. All research projects involve next-generation sequencing of patient samples, analysis of sequencing data, and functional validation of candidate gene variants with correlation to clinical outcomes.

    The selected candidate will benefit from an excellent academic community, a thriving and multidisciplinary research environment, and a close interaction with the clinical teams. Postdocs will have many opportunities to attend major conferences, have a competitive salary, career development training and the ability to develop independent collaborations. Applicants should have a PhD or MD and be capable of managing their own projects as well as collaborating with other groups. A background in molecular biology is preferred.

    This is a temporary, full-time position of two years, with potential of extension, and is available immediately. Interested applicants should send a current CV to Evan Braunstein (ebrauns3@jhmi.edu)

    For more information, please visit: https://www.braunstein.team/

  • Job Description:
    This NIH-funded position is for a highly motivated, goal-oriented, and organized postdoctoral research fellow to work on exciting projects in women health research at Johns Hopkins University. The lab of the PI, Dr. Mostafa Borahay, MD, PhD; is expanding with recent additional NIH funding.

    The fellow will work to understand the pathogenesis and examine novel therapeutics for uterine leiomyomas, the most common tumor of the female reproductive system. The lab is also studying the regulation of menstruation including immune regulation. For more information about the lab, including recent publications, please visit https://borahay.wixsite.com/borahaylab.

    Johns Hopkins University, the top US university in research funding, provides an outstanding environment for state-of-the-art research and an opportunity for cross-disciplinary collaboration.

    Responsibilities:

    • Critically reviewing available literature and design research work accordingly.
    • Planning, conducting, and troubleshooting and completing experiments in several projects.
    • Performing data analysis, preparing manuscripts, presenting at national conferences.
    • Preparing applications for funding.
    • Participating on collaborations both within and outside the institution as discussed with the PI.
    • Adopting techniques currently used in the lab and learning new ones as necessary.
    • Working as a team member with other lab members.
    • Accurately documenting experiments and results in a detailed laboratory notebook.
       

    Knowledge, Skills, and Abilities

    • Fundamental molecular and cellular biology including biochemistry, cell culture, proliferation, cell death, flow cytometry, protein science, Western Blotting, RNA, DNA …
    • Data analysis and graphical representation, manuscript and grant preparation
    • Candidate is expected to learn new skills as necessary.

    Candidate is expected to demonstrate successful publication in reputable journals.

    Additional Opportunity
    Those interested can participate in ongoing clinical trials which includes interaction with patients, handling Institutional Review Board (IRB) communications and other relevant clinical research activities.

    Education
    M.D and/or PhD Degree

    Work Environment
    Clinical and laboratory environment; requires working with human and animal cells/cell lines, blood, and or bodily fluids; effective communication and interpersonal skills.

    Work is at Johns Hopkins School of Medicine, Department of Ob/Gyn, Baltimore, MD, USA. Hired fellows get the standard salary and benefits of postdocs at Johns Hopkins University.

    Women and Minorities are highly encouraged to apply. Johns Hopkins University is an equal opportunity employer.

    To apply: Send CV, cover letter/personal statement, 2-3 references to Dr. Borahay mboraha1@jhmi.edu

  • PI: Ronadip Banerjee, MD, PhD 

     Job Description:
    The Banerjee Lab in the Division of Endocrinology, Diabetes & Metabolism, at the Johns Hopkins School of Medicine is seeking to hire a postdoctoral fellow to lead and develop new research project(s).

    The focus of the lab is pancreatic islet biology and elucidating novel molecular mechanisms underlying diabetes. We are currently focused on understanding how islets within pregnant mothers adapt to the changing metabolic requirements during pregnancy and the postpartum.  We hope to identify how dysregulation of these processes leads to gestational diabetes, and the future risk of type 2 diabetes in mothers postpartum. To address these questions, we use a variety of techniques in molecular biology, cell biology, and genetics, including single-cell RNA sequencing, mouse genetic models, in vivo metabolism studies, immunohistochemistry, etc. The lab also has expertise and tools to study prolactin receptor (PRLR) biology and is examining its role both in islets and other tissues. Additional information can be found at the lab website:  https://www.rrbanerjeelab.org/

    The lab recently relocated to the Johns Hopkins School of Medicine and is supported by both NIH (R01) and startup funds, permitting highly motivated candidates the resources and freedom to pursue any of several projects. 

    Requirements:
    An MD and/or PhD in a science-related field, excellent written and verbal communication skills, strong work ethic and the ability to work interactively are required. Willingness to work with animal models and human islets is required; prior experience with mouse models is highly desirable. Experience in islet biology or diabetes is desirable but not essential. Postdocs who are strong candidates for postdoctoral fellowships are strongly preferred.  

    How to apply:
    We are actively searching for a postdoctoral fellow to begin as soon as possible in Fall 2021. To apply, please send a CV, cover letter, and contact information for at least 3 references to Dr. Banerjee at rrbanerjee@jhmi.edu. The positions will remain open until filled. Salary and fringe benefits will be compliant with guidelines established by the Johns Hopkins University School of Medicine.

  • The Maynard Lab is seeking a highly motivated postdoctoral candidate to collaborate on current funded projects. Our research involves the investigation of immunobiological factors that contribute to cancer health disparities in racial/ethnic minorities and underserved populations. We also investigate the role of inflammation-associated P2 purinergic receptors in cancer initiation and aggressiveness . Specifically, projects are aimed at therapeutically targeting P2 purinergic receptors for the treatment of aggressive prostate cancer and characterizing P2 purinergic receptors in pancreatic cancer.

    To apply: please send a statement of research interests and career goals, CV, and three references to Maynard@jhmi.edu

  • Description:
    The Johns Hopkins University is looking for two Postdoctoral Fellows (2 years each) to assist with development of critical research and infrastructure of the recently launched University of California-Johns Hopkins University (UCSF-JHU) Opioid Industry Documents Archive. Fellows will take up their positions on January 1, 2022.

    The UCSF-JHU Opioid Industry Documents Archive, established in Spring 2021, is a digital collection of publicly disclosed opioid litigation materials. The Archive contains emails, memos, presentations, sales reports, training materials, budgets, audit reports, meeting agendas and minutes, expert witness reports, and depositions of pharmaceutical industry executives. The Archive provides a freely accessible digital resource for use by researchers, journalists, policymakers, and the public. The Archive provides an unparalleled opportunity to investigate scientific, legal, regulatory, and marketing questions, and apply computational as well as other diverse analytic methods, to generate fundamental new knowledge about the origins of the epidemic, and to inform changes to policies and practice to prevent future harms.

    The Postdoctoral Fellows will pursue original, publishable research using materials housed in the Archive and work closely with the Archive research team to enhance the accessibility and usability of archival materials. The fellows will take a leadership role in developing an effective organizational structure of the large volume of diverse materials housed in the Archive to facilitate a wide range of multi-disciplinary research endeavors. As part of their responsibilities, fellows will oversee research assistants charged with specific organizational and research tasks. Fellows will be mentored by and work closely with researchers and information specialists leading this work at JHU.  Fellows will be housed at the Johns Hopkins School of Nursing or the Johns Hopkins School of Medicine and will be affiliated with the Center for Medical Humanities and Social Medicine and the Institute of the History of Medicine.

    Position Start Date: January 1, 2022
    Position End Date: December 31, 2023

    Qualifications:
    Fellows should be well-versed in the history and social context of the ongoing harms associated with opioid overuse—which has become known as the “opioid epidemic” in the US, and/or be knowledgeable about research in related areas, such as the history, regulation, and impact of the pharmaceutical, tobacco, or food industries; agnotology; and the commercial determinants of health. We especially welcome applicants with training in social inequities, racism, intersectional perspectives, and political economy. Scholars with relevant prior publications and/or dissertation research are encouraged to apply. Fellows should be innovative scholars with excellent research, communication, and organizational skills; be comfortable managing multiple tasks in a high-paced research setting; and have experience with leadership and/or supervisory roles.

    Applicants with doctoral degrees in anthropology, sociology, history, history of medicine, public health, health policy, nursing, American studies, and related fields with experience or interest in the digital humanities are eligible to apply. Dual degree trained scholars and health care providers, and interdisciplinary scholars are welcome.

    Application Instructions:
    Applicants should submit a cover letter, C.V., and contact information for three references via Interfolio submission. Applications and related materials are due by November 1, 2021. Review of applications will begin November 1, 2021, and will continue until a suitable candidate is found.

    Application link: https://apply.interfolio.com/95907

    Johns Hopkins University is an equal opportunity employer and does not discriminate on the basis of gender, marital status, pregnancy, race, color, ethnicity, national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, other legally protected characteristics or any other occupationally irrelevant criteria. The University promotes Affirmative Action for minorities, women, individuals who are disabled, and veterans. Johns Hopkins University is a drug-free, smoke-free workplace.

    Salary and benefits details are available here: https://www.hopkinsmedicine.org/som/offices/pda/policies.html

    Questions can be addressed to Cecilia Tomori at ctomori1@jh.edu

 
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