Principal Investigator:
Wenzhen Duan, M.D., Ph.D., M.S.
Department:
Psychiatry and Behavioral Sciences
The goals of the Translational neurobiology Laboratory are to understand the pathogenesis and cell death pathways in neurodegenerative disorders to reveal potential therapeutic targets for pharmaceutical intervention; to investigate endogenous survival pathways and try to induce these pathways to restore full function or replace lost neurons; and to identify biomarkers to mark disease function or replace lost neurons; and to identify biomarkers to mark disease progression and evaluate therapeutics. Our research projects focus on models of Huntington's disease and Parkinson's disease. We use a combination of cell biology and transgenic animal models of these diseases.
Research Areas: Huntington's disease, neurodegenerative disorders, neurobiology, cell biology, Parkinson's disease