Our lab is focused on determining the role of hypoxia in breast cancer metastasis. We are particularly interested in the changes in the extracellular matrix that occur under hypoxic conditions and promote cancer cell migration.

Lauren Jantzie, Ph.D. and colleagues across Johns Hopkins are identifying new biomarkers — measurable, physical signs — to help identify pediatric heart disease and brain injury. Along with Allen Everett, M.D., a leader in pediatric biomarker discovery, initially in sickle cell disease and subsequently in birth injury, congenital heart disease repair, ECMO, prematurity and pulmonary hypertension, Dr. Jantzie directs the Pediatric Proteome Center and integrates cutting edge molecular medicine with clinical innovation.