Obstructive Lung Disease Research Program

The Johns Hopkins Obstructive Lung Disease Section has a diverse portfolio of research activities. These include engagement in team science at the national level through multicenter studies and locally through transdisciplinary work across the University and through community-based research. Johns Hopkins has been a part of American Lung Association Airways Clinical Research Centers for many years and currently serves a as the data coordinating center. JHU is a site for the Genetic Epidemiology of COPD Program (COPD Gene) and the SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS) program, as well as the NHLBI's Precision Interventions for Severe and/or Exacerbation Prone Asthma (PrecISE) Network. The Division participates in industry-sponsored multicenter clinical trials that are available to eligible patients. There is a strong history of investigation of environmental influences on obstructive lung disease and this work is based in the BREATHE Center (Bridging Research, Lung Health, and the Environment). The Breathe Center serves as a home for a multidisciplinary group of investigators that include adult and pediatric pulmonologists, as well as biostatisticians, environmental scientists, and behavioral scientists. The BREATHE Center has been supported by NIH and EPA funding and includes the Center for Childhood Asthma in the Urban Environment and the CURE COPD Programs. The clinical research programs are synergistic with the basic science and translational work and provide a platform for training the next generation of scientists. Examples of recent and ongoing research programs are listed below.

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