Research in the Medical Intensive Care Unit

We are committed to improving the health of today's patients and of our patients in the future. One of the ways we do this is by advancing the state of medical knowledge with cutting edge research.

Our Physicians

We were members of the National Institutes of Health Acute Respiratory Distress Syndrome Network (ARDSNet) since its inception in 1994. This organization conducted large, multicenter clinical trials of promising new treatment strategies for patients with ARDS and related disorders. We contributed to all 11 of the ARDSNet trials. Johns Hopkins investigators led two of the previous trials. We are now actively involved with the National Institutes of Health Prevention and Early Treatment of Acute Lung Injury Network (PETAL Network).

Areas of Active Investigation

  • Acute Respiratory Distress Syndrome, Acute Lung Injury
  • Mechanical ventilation
  • Lung-protective ventilation in Acute Respiratory Distress Syndrome
  • Predictive models in Acute Respiratory Distress Syndrome
  • Epidemiology of critical care and critical illness
  • Prevention and Early Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome
  • Physical Medicine and Rehabilitation in the Intensive Care Environment
  • Long-term physical, cognitive and mental health outcomes after critical illness
  • Mechanisms of resolution of acute lung injury and ARDS
  • Oxidant injury in acute lung injury and ARDS
  • Pulmonary endothelial antioxidant regulation

  • Endothelial barrier function
  • Regulational determinants of acute lung inflammation and repair
  • Regulatory T cells in Lung Injury and its Repair
  • Modulation of Alveolar Macrophage Innate Immune function during ARDS
  • Age-dependent lung immune responses in acute lung injury and ARDS
  • Chronic obstructive lung disease (COPD)
  • Large airway physiology
  • Pleural physiology
  • Critical Care Triage
  • Sleep and respiratory monitoring in the ICU
  • Extracorporeal Membrane Oxygenation (ECMO) for Acute Respiratory Failure


Johns Hopkins Bayview Medical Center
Asthma and Allergy Building
Second Floor
5501 Hopkins Bayview Circle
Baltimore, MD 21224


Faculty at the Division of Pulmonary & Critical Care Medicine research diseases in pulmonology, critical care and sleep medicine, as well as societal aspects of medicine. Lean more about our areas of research.

research scientist