Child and Adolescent Research Volunteers Needed

ADHD | Anxiety | Autism Eating DisordersMood Disorders | ObesityPsychosis | Schizophrenia | Substance Use DisordersHealthy Volunteers

Notice to researchers» 

Attention Deficit Hyperactivity Disorder (ADHD)

Defining the Sluggish Cognitive Tempo Phenotype in Children
We are recruiting participants for a research study to understand how children described by their parents as moving or working much more slowly than others their age concentrate and pay attention. We hope to learn about the work style of these children, including whether this slower performance is associated with other differences in their thinking or attention skills. Online screening is at bit.ly/SlowMovingKids If eligible, there will be a telephone interview and one visit to Kennedy Krieger Institute in Baltimore, Maryland (lasting about 2 hours) to complete attention, language, and behavioral tests. There are no medical benefits or significant risks, but you will receive a brief report of your child’s testing results. Compensation is $25.00 at completion of testing. (IRB Protocol#: IRB00130421) Principal Investigator: Lisa A. Jacobson, Ph.D., ABPP-CN. IRB Contact information: Research Coordinator Lisa Ferenc, MA. For questions, call number: 443-923-4469. Download flyer

Be a Part of Brain Research! (ages 8-12)
Dr. Keri Rosch and colleagues at the Center for Neurodevelopmental and Imaging Research at Kennedy Krieger Institute are recruiting children between the ages of 8 and 12 years to participate in a research study of cognitive control and delay discounting. This study is examining the brain basis of ADHD in children. We are looking for boys and girls with ADHD as well as children who do not have ADHD to participate as “comparison subjects”. The study involves paper and pencil tasks, computer activities and a Magnetic Resonance Imaging (MRI) of the brain. None of these tests are harmful or painful. There are no direct medical benefits from taking part in the study. The study involves one to two days of testing and MRI. Participants will receive $50.00 per day of study participation and a picture of their brain. Parents will receive a report of the IQ test administered to their child. All testing is done free of charge. This study, Delay Discounting in Children with ADHD: Neuroimaging and Behavioral Correlates, has been reviewed and approved by the Johns Hopkins Institutional Review Board (IRB00032351) and is sponsored by the National Institute of Mental Health. For more information about this study, please contact Mary Martinelli at (443) 923-9258 or by email (CNIR@kennedykrieger.org).

Be a Part of Brain Research! (ages 8-12)
Dr. Karen E. Seymour of the Kennedy Krieger Institute and Johns Hopkins School of Medicine is recruiting children with and without Attention Deficit Hyperactivity Disorder (ADHD) as well as children with ADHD and other co-occurring diagnoses (e.g., anxiety, depression) between 8 and 12 years of age to participate in a research study of emotion regulation and frustration tolerance in children with ADHD. The study involves paper and pencil tasks, computer activities, and a MRI scan of the brain. None of the tests are harmful or painful and are done free of charge. There are no direct medical benefits for participating in the study. The duration of the study is one to two days. Participants will receive a $50 check for each day of study participation and a picture of their brain. Parents will receive a report summarizing the IQ testing administered to their child. This study, Neurobehavioral Correlates of Frustration in ADHD, is sponsored by the National Institute of Mental Health. For more information about this study, please contact Mary Martinelli at (443) 923-9258 or CNIR@kennedykrieger.org. Principal Investigator: Karen E. Seymour, Ph.D. Study Number: IRB00063119.

Be a Part of a Brain Research Study! (ages 8-12)
Dr. Stewart H. Mostofsky of the Kennedy Krieger Institute and Johns Hopkins School of Medicine is recruiting children with Attention Deficit Hyperactivity Disorder (ADHD) between 8 and 12 years of age to participate in a study of behavior and brain function before and after movement-based Tai Chi training. This study, Movement-Based Mindfulness Training for Children with ADHD, involves paper and pencil tasks, computer activities, transcranial magnetic stimulation (TMS, a painless, noninvasive brain stimulation technique), an EEG, MRI, and Tai Chi sessions. None of the tests are harmful or painful and are done free of charge. There are no direct medical benefits for participating in the study. The duration of the study is two days, with 8 weeks of Tai Chi classes in between. Participants will receive a $100 check and free Tai Chi classes. Parents will receive a report summarizing the IQ testing administered to their child. For more information about this study, please contact Heather Thompson at (443) 923-9268 or CNIR@kennedykrieger.org. Stewart H. Mostofsky, M.D.: Principal Investigator Protocol Number: IRB00040084.

Assess Effectiveness and Safety of a Medication for ADHD (ages 6-12)
The purpose of this research study is to assess the effectiveness and safety of Molindone Hydrochloride Extended-Release Tablets also known as Moban (SPN-810) in reducing the frequency of impulsive aggression behaviors in pediatric patients with ADHD when taken along with standard ADHD treatment. This is a research study that is being conducted by Dr. Robert Findling at Kennedy Krieger Institute. The purpose of this research study is to assess the effectiveness and safety of Molindone Hydrochloride Extended-Release Tablets also known as Moban (SPN-810) in reducing the frequency of impulsive aggression behaviors in pediatric patients (ages 6 to 12 years) with ADHD when taken along with standard ADHD treatment. Participants will receive psychological, behavioral, and medical testing, including behavioral assessments, physical examinations, blood draws, vital signs, ECGs, urine drug screen, and pregnancy testing for females. There will be a reimbursement of $82.00 for each outpatient visit to compensate individuals for time and travel during participation in the research study. For more information about this research study, please contact the Study Coordinator (443) 923-2637 or by email at ResearchTrials@kennedykrieger.org Research study Sponsor: Forest Research Institute, Inc. PI: Robert Findling, M.D., M.B.A. Johns Hopkins Medicine-IRB No. – IRB00088933. Download flyer


Anxiety

Breathing Biofeedback for Panic and Anxiety Disorders in Children and Adolescents (ages 9-17)
This study is testing the efficacy of the Free-spira Breathing System, a pharmaceutical-free, FDA-cleared, at home device, for use in children and adolescents with anxiety and panic disorder. By instructing how to adjust breathing rate and depth via audio and visual cues, it aims to normalize your respiratory pattern. Previous clinical studies have shown that using the Free-spira Breathing treatment for four weeks can normalize respiratory patterns in adults. This breathing system includes a small hand-held sensor to measure breathing rate and the level of exhaled carbon dioxide in each breath, as well as a hand-held tablet computer with the Free-spira application. The application provides easy-to-follow audio and visual instructions that guide you through prescribed breathing sessions. While it has been shown to be safe and effective for adults suffering from anxiety, it has not yet been tested in children and adolescents. To participate in this study, individuals must be between 9 - 17 years of age and have a current diagnosis of an anxiety disorder and OCD, panic disorder, or a prior diagnosis of two of the following three disorders: social phobia, separation anxiety, and generalized anxiety disorder. The research study entails four office visits to Hopkins over the span of 2 months, with each visit lasting approximately two hours, as well as four follow-up phone calls over a one-year period. Individuals will be compensated $60 for their participation in this study. For more information about this research study, please contact the Study Coordinator at (443) 287-2292 or by email at hopkinsfreespirastudy@gmail.com Research Study Sponsor: Pediatric Anxiety Fund, Department of Psychiatry & Behavioral Sciences; PI: Marco A Grados, M.D., M.P.H  (IRB No. - IRB00097094)


Autism

Motor Skill Learning in Autism: Assessment and Treatment of Altered Patterns of Learning (ages 8-12)
Dr. Stewart H. Mostofsky of the Kennedy Krieger Institute and Johns Hopkins School of Medicine is recruiting children with and without high-functioning autism between 8 and 12 years of age to participate in a study of attention, learning, memory, and motor skills. The study involves paper and pencil tasks, computer activities, and MRI scan of the brain. None of the tests are harmful or painful and are done free of charge. There are no direct medical benefits for participating in the study. The duration of the study is two to three days. Participants will receive a $100 check and a picture of their brain. Parents will receive a report summarizing the IQ testing administered to their child. For more information about this study, please contact Alyssa Tiedemann at (443) 923-9263 or CNIR@kennedykrieger.org (IRB Protocol # NA_00027073)


Eating Disorders

Brain and Appetite Research Study: Neurobehavioral Influences on Body Weight in Adolescents (ages 3-13 and biological mother)
Johns Hopkins Hospital is conducting a research study in children (3-13 y old) and their biological mothers. The study involves two visits for 4-4.5 hours each. Study includes fMRI scan (child only), body composition measurements (height, weight, waist), questionnaires, computer tasks, buffet meals, and saliva collection. Compensation is up to $125, plus $10 travel costs for each visit. Children candidates must be 8-13 y old, must not be claustrophobic or have any metal implants. All candidates must speak English fluently and not have any major medical or psychiatric conditions. Candidates must not have any food or nut allergies or be on any medications affecting weight or appetite. Contact information: Call 410-955-5099 or email apapant1@jhu.edu. PI: Susan Carnell, PhD (IRB #: NA_00092328) DOWNLOAD FLYER

Brain and Appetite Research Study: Neurobehavioral Influences on Body Weight in Adolescents (ages 14-18 and biological mother)
Johns Hopkins Hospital is conducting a research study in adolescents (14-18 y old) and their biological mothers. The study involves three visits for 3-3.5 hours each. Study includes fMRI scan (adolescent only), body composition measurements (height, weight, waist), questionnaires, computer tasks, liquid and buffet meals, and saliva collection. Compensation is up to $245, plus $10 travel costs for each visit. Adolescent candidates must be 14-18 y old, must not be pregnant, claustrophobic or have any metal implants. All candidates must speak English fluently and not have any major medical or psychiatric conditions. Candidates must not have any food or nut allergies or be on any medications affecting weight or appetite. Contact information: Call 410-955-5099 or emailapapant1@jhu.edu. PI: Susan Carnell, PhD (IRB #: NA_00092328) DOWNLOAD FLYER


Mood Disorders

Assess Effectiveness and Safety of a Medication for Major Depressive Disorder (ages 7-17)
A Research Study to determine whether an investigational drug called vilazodone is safe and effective to treat symptoms of major depressive disorder in children and adolescents. This is a research study that is being conducted by Dr. Robert Findling at Kennedy Krieger Institute to determine whether vilazodone, an SSRI antidepressant for the treatment of major depressive disorder (MDD), is safe and effective for children and adolescents (ages 7 to 17 years). Eligible children and adolescents, with symptoms of MDD, will visit the Kennedy Krieger Institute for nine outpatient visits over a 10-week period; each outpatient visit will last about 3 hours. Participants will receive psychological, behavioral, and medical testing, including behavioral assessments, physical examinations, blood draws, vital signs, ECGs, urine drug screen, and pregnancy testing for females. There will be a reimbursement of $50.00 for each outpatient visit to compensate individuals for time and travel during participation in the research study. For more information about this research study, please contact the Study Coordinator at (443) 923-2637 or by email at ResearchTrials@kennedykrieger.org Research study Sponsor: Forest Research Institute, Inc. PI: Robert Findling, M.D., M.B.A. Johns Hopkins Medicine-IRB No. – IRB00054798. Download flyer

A Phase 3, Multicenter, Four-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Efficacy And Safety Trial Of Flexible Doses Of Oral Ziprasidone In Children And Adolescents With Bipolar I Disorder (Current Or Most Recent Episode Manic) (ages 10-17)
This research study is being conducted by centers across the United States to help determine if ziprasidone is a safe and effective treatment for symptoms associated with bipolar I disorder (with a current or most recent episode being manic). Kennedy Krieger Institute is looking for children with bipolar I disorder (with a current or most recent episode being manic), ages 10 through 17 years, to participate in this research study. The research study involves up to seven visits to Kennedy Krieger Institute over seven weeks, each lasting about four hours. There are no direct medical benefits for participating in this research study. For each completed visit, participants will receive reimbursement of $45.50 for their time and travel expenses.   Please ask a study team member for spe cifics. All testing is done free of charge. For more information about this research study, please contact the Study Coordinator at (443) 923-3850 or by email at ResearchTrials@kennedykrieger.org Research study Sponsor: Pfizer, Inc. PI: Robert Findling, M.D., M.B.A. IRB No. – NA_00093875 www.clinicaltrials.gov (NCT02075047)

A Research Study to assess the efficacy of Vortioxetine at improving depressive symptoms in children with Major Depressive Disorder (ages 7-17)
This is a research study that is being conducted by Dr. Robert Findling at Kennedy Krieger Institute. The purpose of this research study is to assess the efficacy of Vortioxetine at improving depressive symptoms in children with Major Depressive Disorder, for children and adolescents (ages 7 to 17 years). Participants will receive psychological, behavioral, and medical testing, including behavioral assessments, physical examinations, blood draws, vital signs, ECGs, urine drug screen, and pregnancy testing for females. There will be a reimbursement of $50.00 for each outpatient visit to compensate individuals for time and travel during participation in the research study. For more information about this research study, please contact the Study Coordinator (443) 923-2637 or by email at ResearchTrials@kennedykrieger.org  Research study Sponsor: Forest Research Institute, Inc. PI: Robert Findling, M.D., M.B.A. Johns Hopkins Medicine-IRB No. – IRB00108928 and IRB00103718. Download flyer 

Assess Effectiveness and Safety of a Medication for Bipolar I Disorder (ages 10-17)
This study is being conducted to see how safe and how effective an investigational drug called Equetro® (carbamazepine) Extended Release Capsules compared to a Placebo will work in children and adolescent diagnosed with Bipolar I Disorder. This is a research study that is being conducted by Dr. Robert Findling at Kennedy Krieger Institute. This study is being conducted to see how safe and how effective an investigational drug called Equetro® (carbamazepine) Extended Release Capsules compared to a Placebo will work in children and adolescent (ages 10-17 years) diagnosed with Bipolar I Disorder. Participants will receive psychological, behavioral, and medical testing, including behavioral assessments, physical examinations, blood draws, vital signs, ECGs, urine drug screen, and pregnancy testing for females. There will be a reimbursement of $75.00 for each outpatient visit to compensate individuals for time and travel during participation in the research study. For more information about this research study, please contact the Study Coordinator (443) 923-2637 or by email at ResearchTrials@kennedykrieger.org Research study Sponsor: Forest Research Institute, Inc. PI: Robert Findling, M.D., M.B.A. Johns Hopkins Medicine-IRB No. – IRB00070823. Download flyer

Related studies:


Obesity

Brain and Appetite Research Study: Neurobehavioral Influences on Body Weight in Adolescents (ages 3-13 and biological mother)
Johns Hopkins Hospital is conducting a research study in children (3-13 y old) and their biological mothers. The study involves two visits for 4-4.5 hours each. Study includes fMRI scan (child only), body composition measurements (height, weight, waist), questionnaires, computer tasks, buffet meals, and saliva collection. Compensation is up to $125, plus $10 travel costs for each visit. Children candidates must be 8-13 y old, must not be claustrophobic or have any metal implants. All candidates must speak English fluently and not have any major medical or psychiatric conditions. Candidates must not have any food or nut allergies or be on any medications affecting weight or appetite. Contact information: Call 410-955-5099 or email apapant1@jhu.edu. PI: Susan Carnell, PhD (IRB #: NA_00092328) DOWNLOAD FLYER

Brain and Appetite Research Study: Neurobehavioral Influences on Body Weight in Adolescents (ages 14-18 and biological mother)
Johns Hopkins Hospital is conducting a research study in adolescents (14-18 y old) and their biological mothers. The study involves three visits for 3-3.5 hours each. Study includes fMRI scan (adolescent only), body composition measurements (height, weight, waist), questionnaires, computer tasks, liquid and buffet meals, and saliva collection. Compensation is up to $245, plus $10 travel costs for each visit. Adolescent candidates must be 14-18 y old, must not be pregnant, claustrophobic or have any metal implants. All candidates must speak English fluently and not have any major medical or psychiatric conditions. Candidates must not have any food or nut allergies or be on any medications affecting weight or appetite. Contact information: Call 410-955-5099 or emailapapant1@jhu.edu. PI: Susan Carnell, PhD (IRB #: NA_00092328) DOWNLOAD FLYER


Psychosis

First Episode Psychosis: Longitudinal Characterization of Molecular Biomarker Changes Over the Early Course of Psychotic Disease (ages 13-35)
Researchers are seeking individuals diagnosed with a psychotic disorder to participate in a research study being done to study the cells of patients with psychotic disorders. Your participation may help improve the treatment of psychotic disorders for patients like you. This study is a longitudinal study over the course of three years (only a few visits required per year): you can earn up to $1740. To be eligible for this study, you must be between 13-35 years of age with a psychotic disorder diagnosis – this may include schizophrenia, bipolar disorder, and mood disorders. Qualified participants have the option of undergoing: blood draw, skin biopsy, nasal biopsy, lumbar puncture, and two sessions of brain scanning with MRI technology. To learn more, please call Candice at 443-287-4986 or email at cford15@jhmi.edu. (NA_00082086, Principal Investigator: Akira Sawa, MD, PhD)


Schizophrenia

An Adaptive, Phase IIb/III, Double-Blind, Randomized, Placebo- Controlled, Multi-Center Study of the Safety and Efficacy of NaBen® (Sodium Benzoate), a D-Amino Acid Oxidase Inhibitor, as an Add-on Treatment for Schizophrenia in Adolescents (ages 12-17)
This research study is being conducted by centers across the United States to evaluate the safety and effectiveness of NaBen® (sodium benzoate), compared with placebo, in male and female adolescents, ages 12 to 17 years, with schizophrenia. The research study involves up to seven visits to Kennedy Krieger Institute over ten weeks, each lasting about 2-3 hours. There are no direct medical benefits for participating in this research study. For each completed visit, participants will receive reimbursement of $65.00 for their time and travel expenses. Please ask a study team member for specifics. All testing is done free of charge. For more information about this research study, please contact the Study Coordinator at (443) 923-3850 or by email at ResearchTrials@kennedykrieger.org Research study Sponsor: SyneuRx International Corp. PI: Robert Findling, M.D., M.B.A.IRB No. – IRB00030540 www.clinicaltrials.gov (NCT01908192)

Related studies:


Substance Use Disorders

Adolescent Reward Study (ages 13-18)
Adolescent Subjects Needed! Study of Reward-related Behavior. Researchers at the Johns Hopkins University are seeking adolescents, ages 13-18, to participate in a new study. Participants perform cognitive tests/games and answer questions about their life, emotions, behaviors, and stressful events. The study involves no medications, no blood draws etc. Qualified people will be compensated at no cost to them. Participants under the age of 18 years will only be enrolled with consent provided by a parent or guardian. You may be eligible if you Are 13-18 years old. The study involves one two-to-three hour session. You will be paid $30 for your participation. If you are interested in participating or would like further information please email: chammo20@jhmi.edu  All emails/calls are confidential. Study #: IRB00093540, PI: Christopher Hammond, M.D.  Download flyer

Adolescent Brain Imaging (MRI) Study (ages 13-18)
Adolescent Subjects Needed! Brain Imaging (MRI) Study Researchers at the Johns Hopkins University are seeking adolescents, ages 13-18, to participate in a new study that uses a brain imaging technique called magnetic resonance imaging, or MRI, and involves cognitive tests/games and answering questions about your life, behaviors, and stressful events. The study involves no medications, no blood draws etc. Qualified people will be compensated and participate at no cost to them. Participants under the age of 18 years will only be enrolled with the consent provided by a parent or guardian. You may be eligible if you are 13-18 years old and have no medical contraindications to completing an MRI scan. The study involves one three hour session, part of which will include the MRI scan. You will be paid $50 for your participation. If you are interested in participating or would like further information please email: chammo20@jhmi.edu. All emails/calls are confidential. Study #: IRB00093540, PI: Christopher Hammond, M.D. . Download flyer

Notice to Researchers: If you are faculty in the Department of Psychiatry and Behavioral Sciences and you wish to post a recruitment ad on this page, please contact Benedicta Kim at bkim@jhmi.edu. You will need to send the IRB-approved recruitment language in paragraph form with a title of the study, the PI, contact information and the IRB Protocol Number. You are responsible for IRB approval of the ad. Please be sure to contact us to remove the ad from this page when recruitment is complete. Thank you.