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Neurosurgical Spine Research and Education Programs

Neurosurgical Spine Education Programs

Neurosurgical Spine Center trainees have the opportunity to work alongside Johns Hopkins’ renowned team of neurosurgeons, participate in complex procedures and learn advanced surgical techniques.

 

Neurosurgical Spine Research Labs

Our researchers leverage the vast resources of Johns Hopkins Medical Institutions’ basic science and clinical research centers to identify new therapeutic options for a variety of spinal diseases.

  • Neurosurgery Spine Research Lab

    The Spinal Research Laboratory is the leading research laboratory in the world dedicated to animal models of spinal conditions. Using novel models and techniques, Dr Sciubba and his collaborators have been able to create new ways to study tumors of the spinal cord and spinal column, spinal paralysis, and spinal fusion physiology. In addition, they consistently test certain spinal devices for effectiveness in the spine. Led by Dr Daniel Sciubba, this laboratory has received annual funding from the National Institute of Health (NIH) and various foundations including: American Association of neurological Surgeons (AANS), Congress of neurological Surgeons (CNS), North American Spine Society (NASS), AOSpine, neurosurgery Research and Education Foundation (NREF), and the AANS/CNS Section on Disorders of the Spine and Peripheral Nerves. Recently, the laboratory has also begun relationships with industry, including K2M and Depuy Spine. In addition, private donations are accepted regularly to h...elp fund various projects. view more

    Research Areas: spine

    Lab Website

    Principal Investigator

    Dan Sciubba, M.D.

    Department

    Neurosurgery

  • Spinal Column Biomechanics Lab

    The Spinal Column Biomechanics Laboratory focuses on the study of various spinal pathologies. The Biomechanics Laboratory studies a wide array of tools and techniques in order to advance spinal surgery for the benefit of patients. With a team of researchers, engineers, and neurosurgeons, the Biomechanics Laboratory participates in the newest developments in applied and translational research. Our facility alongside the International Center for Orthopaedic Advancement at the Johns Hopkins Bayview Medical Center serves as a premiere learning institute. The laboratory not only conducts novel biomechanical studies but also functions as a teaching facility for neurosurgical trainees interested in mastering highly specialized or technical procedures.The Spinal Column Biomechanics Laboratory specializes in applied mechanics, force vector analysis, spinal instrumentation testing and development of novel spinal reconstructions.

    Research Areas: spine

    Lab Website

    Principal Investigator

    Ali Bydon, M.D.

    Department

    Neurosurgery

  • Spinal Column Surgical Outcomes Lab

    The Spinal Column Surgical Outcomes Laboratory aims to improve the neurological outcomes and functional capacity of patients undergoing spinal surgery. We collect large-scale retrospective patient databases and prospective patient registries to report high-quality data relating to the outcomes of neurosurgical operations. The laboratory participates in the National neurosurgical Quality and Outcomes Database (N2QOD). This multi-institutional collaboration has set forth a 3-year prospective study to benchmark quality and surgical outcome measures across several academic institutions. The Spinal Column Surgical Outcomes Laboratory specializes in biostatistical analysis of large-scale clinical databases, studying the outcomes of traditional and novel spinal procedures, quality control and cost-effectiveness research and clinical trials relating to spinal surgery outcomes.

    Research Areas: spine

    Lab Website

    Principal Investigator

    Ali Bydon, M.D.

    Department

    Neurosurgery

  • Spinal Oncology Lab

    The bony skeleton is one of the most common sites of metastatic spread of cancer and a significant source of morbidity in cancer patients, causing pain and pathological fracture, impaired ambulatory ability and poorer quality of life.

    In our continuous investigation of the mechanism of metastasis in spine tumors and of developing animal models and treatments, our team seeks to understand how cancer cells metastasize to the bony spine.

    Our laboratory develops novel techniques to evaluate our animal models of metastatic spine disease.

    Research Areas: spine cancer, spine, cancer

    Lab Website

    Principal Investigator

    Dan Sciubba, M.D.

    Department

    Neurosurgery

  • The Spinal Fusion Laboratory

    Five to 35 percent of spine fusionprocedures fail, even when using the gold standard treatment of grafting bone from the patient's own iliac crest. Fusion failure, otherwise known as pseudoarthrosis, is a major cause of failed back surgery syndrome (FBSS) and results in significant pain and disability, increasing the need for additional procedures and driving up health care costs. The ultimate goal of the Spinal Fusion Laboratory is to eliminate pseudoarthrosis by using animal models to study various strategies for improving spinal fusion outcomes, including delivery of various growth factors and biological agents; stem cell therapies and tissue engineering approaches.

    Research Areas: failed spine surgery, pseudoarthrosis, spine fusion

    Lab Website

    Principal Investigator

    Timothy Witham, M.D.

    Department

    Neurosurgery

 
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