Clinical Trials

Current Studies

The Pituitary Center is actively recruiting participants for the following studies:

Glucocorticoid Receptor Antagonism in the Treatment of Cushing Syndrome (GRACE): A Phase 3 Study of the Efficacy and Safety of Relacorilant (IRB00188375)

Principle Investigator: Roberto Salvatori, MD (salvator@jhmi.edu or 410-955-3921)
Objective: This is a study to determine if the research drug, relacorilant, is safe and effective for people with Cushing's syndrome.
Eligibility Criteria: People with Cushing's Syndrome (Cushing's Disease).
More information on clinicaltrials.gov: NCT03697109

PATHFNDR: Paltusotine Acromegaly Therapy Featuring a Non-Invasive Daily Regimen (IRB00274205)

Principle Investigator: Roberto Salvatori, MD (salvator@jhmi.edu or 410-955-3921)
Objective: This is a study to determine if the research drug, paltusotine, is safe and effective in controlling growth hormone (GH) levels in people with acromegaly.
Eligibility Criteria: People 18 years or older with acromegaly who are currently receiving and have responded to injections of octreotide or lanreotide as treatment.
More information on clinicaltrials.gov: NCT04837040

The Management of Acromegaly (MACRO) Registry (IRB00248200)

Principle Investigator: Roberto Salvatori, MD (salvator@jhmi.edu or 410-955-3921)
Objective: This is a study to survey the treatment of acromegaly through electronic data collection.
Eligibility Criteria: Patients with acromegaly.

Learn more

To learn more about this clinical trial please visit: http://clinicaltrials.gov/.
If interested, contact the Study Coordinator at 410-502-0033 or Roberto Salvatori, MD, Principal Investigator at 410-955-3921.

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