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Mesial Temporal Sclerosis

What is mesial temporal sclerosis?

Mesial temporal sclerosis (scarring in the inner portions of the temporal lobe) may be caused by oxygen starvation to the brain, head trauma, or brain infection, but can also occur without an apparent cause.

Over time, neurons die and scar tissue tends to form within the hippocampus and amygdala (areas in the temporal lobe responsible for emotions and short-term memory).

Mesial temporal sclerosis (also known as hippocampal sclerosis) can cause a form of temporal lobe epilepsy with partial (focus) seizures that can spread or secondarily generalize and affect other areas of the brain.

Treatments for temporal lobe epilepsy caused by mesial temporal sclerosis can include anticonvulsant medications and surgery.

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For more information about mesial temporal sclerosis or to meet with our doctors, request an appointment at the Epilepsy Center.

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