Principal Investigator: Jose Suarez, M.D.

The PMCOE in neurocritical care provides a platform for cutting-edge AI/ML research in neurocritical care. Led by Jose Suarez, the center houses a team of data scientists and researchers who leverage a large Big Data analytics platform with high-frequency physiological waveform signals recorded from over 2,000 patients in the neurocritical care unit. This resource provides an excellent foundation for fellows to engage in AI/ML research and explore novel approaches to patient management using large-scale data.

Principal Investigator: Daniel Hanley, M.D.

Housed at the intersection of neurology and neurocritical care, BiOS provides a platform for fellows to engage in clinical trials such as BEACH and ReASSESS, and work with large datasets of clinical trial patients with longitudinal outcomes This includes CLEAR-III and MISTIE-III trials. Led by Professor Daniel Hanley, founding director of the NCCU at Hopkins, BiOS offers fellows an opportunity to collaborate on significant clinical research initiatives.

Principal Investigator: Susanne Muehlschlegel, M.D., M.P.H.

Led by Dr. Muehlschlegel, this research focuses on improving communication in critical care settings and advancing the science of neuroprognostication. 

Principal Investigator: Sung-Min Cho, D.O., M.H.S.

Clinical and translational research investigating approaches to mitigate acute brain injury in patients using the ECMO device and devising novel ECMO devices, a unique area of expertise at Johns Hopkins. 

Principal Investigators: Vishank Shah, M.B.B.S., Austen Lefebvre, M.D., Kate Rosenblatt, M.D., M.H.S.

This research team explores innovative applications of invasive and non-invasive multimodality monitoring in patients with subarachnoid hemorrhage, sepsis and other complex neurological conditions. 

Principal Investigator: Austen Lefebvre, M.D.

Translational research in collaboration with the Applied Physics lab aimed at developing novel optical methods for real-time neurological monitoring, offering non-invasive alternatives for critically ill patients. 

Investigating plasma biomarkers in intracerebral hemorrhage (ICH), ECMO, and acute brain injury, with potential for early detection and better patient outcomes. 

Exploring novel MRI techniques for early detection and prognostication of neurological injury, white matter disease.

Investigating the role of simulation-based education and virtual reality for procedural training, helping to shape the next generation of ICU leaders.