In This Section      

Barrett’s Esophagus & Esophageal Cancer: What You Need to Know

Barrett’s esophagus is a condition that can arise from acid reflux and increase your risk of developing esophageal cancer. Esophageal cancer occurs inside the esophagus, which is the tube in the throat that moves food from the mouth to the stomach.

Barrett’s esophagus occurs when the cells in the lining of your esophagus are damaged from acid reflux. If those cells develop abnormally, this can result in dysplasia, a pre-cancerous condition that can lead to esophageal cancer if left untreated. 

Johns Hopkins Sidney Kimmel Comprehensive Cancer Center has one of the leading esophageal cancer treatment programs in the nation, including a special focus on monitoring and treating Barrett’s esophagus to prevent cancer.

Barrett’s Esophagus & Esophageal Cancer: What You Need to Know

father and son using a laptop
  • Barrett’s esophagus is a complication of gastrointestinal reflux disease (GERD). An estimated 10-15 percent of patients with GERD will develop Barrett’s esophagus.
  • Approximately one in 860 Barrett’s esophagus patients will develop esophageal cancer, meaning the risk is statistically low.
  • Barrett’s esophagus is twice as common in men than in women, and usually targets Caucasian men over the age of 50 who have had heartburn for many years.
  • Barrett’s esophagus, while not reversible, is treatable and should be monitored closely by a trained specialist to minimize your risk of developing cancer.

Patient Resources

Request an Appointment


Why Choose Johns Hopkins for Monitoring Barrett’s Esophagus?

female physician smiling

Our Physicians

At Johns Hopkins, our gastroenterologists and esophageal cancer specialists work together to monitor patients with Barrett’s Esophagus. We provide the full range of diagnostic tests and evaluation, ensuring early detection and proactive treatment of esophageal cancer.


researcher using lab equipment

Our Treatments

Our doctors are the world leaders in effective treatments and procedures for Barrett’s esophagus, including cryoablative therapy. This treatment uses freezing technology for elimination of Barrett’s esophagus and less pain compared to other technologies. Learn more about our pioneering research on endoscopic cryotherapy.

Our doctors also offer standard endoscopic treatments for Barrett’s esophagus such as radiofrequency ablation (RFA) and argon plasma coagulation (APC).

Early esophageal cancer can be removed and cured using a minimally invasive non-surgical outpatient endoscopic technique called endoscopic mucosal resection (EMR).

doctor talking to a patient

Our Patient Care

Our team is dedicated to treating patients with Barrett’s Esophagus and educating them about the risk of esophageal cancer and prevention strategies. We provide expert care and compassionate support during your entire course of treatment at Hopkins. Learn more about our patient support services.

Request an Appointment

Maryland Patients



Traveling for Care?

Whether you're crossing the country or the globe, we make it easy to access world-class care at Johns Hopkins.

Outside of Maryland (toll free)

Request an Appointment
Medical Concierge Services

International Patients

Request an Appointment
Medical Concierge Services

blue suitcase