Pediatric Lipid Research and Atherosclerosis

Our Division of Lipid Research and Atherosclerosis focuses on the whole family

Among the oldest of its kind, the Division of Lipid Research and Atherosclerosis at the Children’s Center is also the first in the country to focus on the whole family. Clinician scholars and researchers at the Johns Hopkins Lipid Clinic develop new and better ways to diagnose and treat lipid disorders in children, adolescents and adults.

Early identification and management of risk factors in children for lipid disorders is the focus in the Division of Lipid Research and Atherosclerosis.

Lipid Center of Excellence

The Division of Lipid Research and Atherosclerosis is working to fund a center of excellence in lipid disorders in families, which will focus on the diagnosis, research and treatment of families with lipid disorders — in particular those patients and families with histories of cardiovascular disease, hypertension, stroke, obesity and diabetes. It will integrate research, patient care and training in this specialty, with the goal of finding better ways to treat patients and of training a cohort of future researcher/physicians to advance this important work.

Funding and establishing an endowed center of excellence at Johns Hopkins requires a philanthropic gift or gifts totaling $5 million. Annual allowable income from the endowment will allow the new Lipid Center to expand the mission of the current Lipid Clinic by seeing patients and families suffering from a variety of lipid-related disorders, delving into new areas of scientific inquiry and increasing faculty and staff. Specifically the center director would be able to:

  • Recruit and retain bright, young M.D., Ph.D. faculty — specifically, a molecular biologist and a protein biochemist to elucidate the fundamental basis of elevated HDL disorders and other lipid disorders
  • Support highly original, innovative research on inherited lipid disorders that would not otherwise be funded through traditional sources like National Institutes of Health
  • Provide support for researchers from other disciplines to work on projects within the Lipid Center
  • Purchase technical support and equipment, such as a machine that removes bad cholesterol from patients with sky-high cholesterol levels and early cardiovascular disease
  • Increase the number of patients and the scope of the program to include all diseases associated with elevated lipids, especially adolescents with obesity and metabolic syndrome

In the past, researchers focused on finding treatments and cures for diseases after onset or diagnosis. Building on the legacy of discovery at Johns Hopkins, we want to decipher genetic information in order to prevent cardiovascular disease from even occurring by “turning off” bad risk genes or “turning on” good genes. Establishing a new endowed center of excellence in lipid disorders in families can bring this vision within the realm of possibility.

Our Team

Subroto B. Chatterjee PhD

  • Director, Sphingolipid Signaling and Vascular Biology Laboratory
  • Professor of Pediatrics

Research Interests: Drug discovery and biotechnology, Lipid and vascular biology translational research

Kathleen H. Byrne, M.S.N., C.R.N.P., C.C.R.N.
Clinical manager/Study coordinator

Johns Hopkins University Lipid Clinic
550 N Broadway, Suite 312
Baltimore, MD  21205

Lipid and Atherosclerosis Research

The Division of Lipid Research and Atherosclerosis includes a team of researchers expanding what we know about lipid disorders.

Patient Stories

Managing Lipid Disorders

Megan Gwozdecke has a hard time remembering her first visit to pediatrician Peter Kwiterovich. After all, that visit occurred two decades ago when she was barely 2 years old.

megan gwozdecke

Contact Us

Phone: 410-955-5034

David M. Rubenstein Child Health Building 
200 N Wolfe St, Room 3093
Baltimore, MD 21287