Major Depressive Disorder and Bipolar Disorder Research for the Better

Better Measurements

Using a combination of easily deployed surveys, smartphones, and wearable technology, we hope to intervene earlier, prevent undue suffering, and promote better outcomes.

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Better Biomarkers

We will test whether genetic markers known as polygenic risk scores can help identify individuals who may require more intensive treatment options earlier in their care or may have a higher risk of developing bipolar disorder.

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Individualized Treatments

As part of our precision medicine center, we are also working to identify the types of treatment that work best for an individual patient, including newer treatments such as Ketamine, esketamine, and various brain stimulation techniques.

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Better Delivery of Care

Individuals suffering from mood disorders can be treated in a number of settings, ranging from their homes, to outpatient clinics and, if needed, inpatient units. As part of our precision medicine center, we are working with services delivery experts and the Johns Hopkins office of Telemedicine to determine which types of health care delivery work best for individual patients depending on “where” they are on their illness trajectory.

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Clinical Trials

The Stanley and Elizabeth Star Precision Medicine Center of Excellence in Mood Disorders collaborates with multiple organizations to conduct clinical trials for novel treatments ranging from bench to bedside and vise versa.

Expediting Effective Treatments for Severe Mood Disorders

A $7.5 million gift from philanthropists Stanley and Elizabeth Star is helping Johns Hopkins scientists and clinicians better understand and treat major depression and bipolar disorders.

Charitable Giving

Support diagnosis and treatment advancements and discoveries by Johns Hopkins scientists.