Durability of Respiratory Syncytial Virus Antibodies After Vaccination in Immunosuppressed Persons
Date:
07/23/2026
Citation:
Nauroz Z, Balasubramanian P, Rodrigues M, Arondekar S, Sengsouk I, Hage C, Chahoud M, Green X, Gallo W, Eby Y, Tobian AAR, Werbel WA, Karaba AH. Durability of Respiratory Syncytial Virus Antibodies After Vaccination in Immunosuppressed Persons. Open Forum Infect Dis. 2026 Jul 23;13(8):ofag453. doi: 10.1093/ofid/ofag453. PMID: 42597566; PMCID: PMC13469694.
Abstract
Respiratory syncytial virus (RSV) antibody durability in immunosuppressed persons following RSV vaccination is unknown. In this observational cohort of immunosuppressed persons, peak responses occurred 1 month after vaccination, without significant waning by 6 months; adjuvanted vaccine recipients had higher responses. This suggests RSV antibody durability of at least 6 months and potential augmentation by adjuvanted vaccine.