Dashboards are commonly used in healthcare to monitor and respond to safety and quality data, but few data describe how to best implement dashboards in home infusion therapy. We developed a dashboard for a collaborative of home infusion agencies to monitor an important safety outcome, central line-associated bloodstream infections (CLABSI). We used the Technology Acceptance Model (TAM) to understand key components of implementing a CLABSI surveillance dashboard in a home infusion therapy environment. We interviewed seven primary users of the dashboard to understand how the dashboard was implemented, including barriers and facilitators to its implementation. In this qualitative analysis, we used elements of the TAM to develop a new framework that describes how a dashboard can be implemented and used in a healthcare setting to support others who are developing and implementing quality or safety dashboards in home infusion therapy settings.