Single Monoclonal Antibodies Should Not Be Used for COVID-19 Therapy: A Call for Antiviral Stewardship
Date:
12/17/2024
Citation:
Casadevall A, Focosi D, Pirofski LA, Shoham S. Single Monoclonal Antibodies Should Not Be Used for COVID-19 Therapy: A Call for Antiviral Stewardship. Clin Infect Dis. 2024 Dec 17;79(6):1404-1407. doi: 10.1093/cid/ciae408. PMID: 39115342.
Abstract
The COVID-19 pandemic witnessed the greatest deployment of monoclonal antibody (mAb) therapies for an infectious disease, but all were defeated by SARS-CoV-2 evolution. As new mAbs are developed, the infectious disease community needs stewardship practices to reduce emergence of resistance.