Incidence and Severity of COVID-19 Among Vaccinated Solid Organ Transplant Recipients During the Omicron Wave
Date:
09/01/2022
Citation:
Alejo JL, Chiang TPY, Bowles Zeiser L, Kim JD, Mitchell J, Avery RK, Tobian AAR, Abedon RR, Levan ML, Warren DS, Garonzik-Wang JM, Massie AB, Segev DL, Werbel WA. Incidence and Severity of COVID-19 Among Vaccinated Solid Organ Transplant Recipients During the Omicron Wave. Transplantation. 2022 Sep 1;106(9):e413-e415. doi: 10.1097/TP.0000000000004226. Epub 2022 Jun 3. PMID: 35655363.
Abstract
The Omicron variant has caused an unprecedented surge in SARS-CoV-2 infections among vaccinated people in the United States, owing to high transmissibility, immune evasion, and higher circulating antibodies required to achieve neutralization. Vaccine-derived protection is suboptimal among solid organ transplant recipients (SOTRs).1-5 We studied frequency and severity of COVID-19 breakthrough during the US Omicron wave (December 25, 2021–March 1, 2022) in vaccinated SOTRs, focusing on the effect of preceding antispike antibody level.