Impact of a prescriber-driven antibiotic time-out on antibiotic use in hospitalized patients
Date:
04/24/2019
Citation:
Thom KA, Tamma PD, Harris AD, Dzintars K, Morgan DJ, Li S, Pineles L, Srinivasan A, Avdic E, Cosgrove SE. Impact of a Prescriber-driven Antibiotic Time-out on Antibiotic Use in Hospitalized Patients. Clin Infect Dis. 2019 Apr 24;68(9):1581-1584. doi: 10.1093/cid/ciy852. PMID: 30517592.
Abstract
A multicenter quasi-experimental study of a provider-driven antibiotic "time-out" in 3470 antibiotic courses showed no difference in antibiotic use before and after implementation, but did show a decrease in inappropriate therapy (45% vs 31%, P < .05). Single time-outs without input from antibiotic stewardship teams are insufficient to optimize prescribing.