Chronic hepatitis B (CHB) affects over 300 million people worldwide and increases liver-related mortality 14- fold in the 10% of people with HIV who also have CHB (PWHHB). The goal of the synergistic Cores and Projects in the Hepatitis B HIV Cure Consortium (BICC) is to build a multinational, collaborative cohort of PWHHB to reveal mechanisms of HBV control in people receiving hepatitis B therapy. These data will be integrated into a model of hepatitis B control that will provide a roadmap to developing therapeutics for a hepatitis B functional cure.