A nanopore biosensor for leveling Mtb antigens in blood
Date:
06/15/2022
Locations:
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Lead Investigators:
Summary
In this work, we propose to employ protein-based nanopore technology, which can recognize single peptide detection events to quantify two tuberculosis-specific biomarkers (CFP-10 and ESAT-6), to develop a portable diagnostic and treatment monitoring system for resource-limited areas. Based on our preliminary studies, we are confident that this diagnostic system will benefit the global tuberculosis control effort by improving early diagnosis and treatment monitoring of tuberculosis.