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Chiadi Ndumele, MD, MHS

Ciccarone Center Research

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Chiadi Ndumele, MD, MHS

Chiadi Ndumele, MD, MHS
Ndumele, Chiadi, MD, MHS

Chiadi Ndumele, MD, MHS is an Assistant Professor of Medicine.

View my Johns Hopkins Medicine profile for more information and to request an appointment

Landmark Articles

Hepatic steatosis, obesity, and the metabolic syndrome are independently and additively associated with increased systemic inflammation.

By: Ndumele CE, Nasir K, Conceiçao RD, Carvalho JA, Blumenthal RS, Santos RD.
The goal of this study was to assess the independent and collective associations of hepatic steatosis, obesity, and the metabolic syndrome with elevated hsCRP levels. We evaluated 2,388 individuals without clinical cardiovascular disease between December 2004 and December 2006. Hepatic steatosis was diagnosed by ultrasound, and the metabolic syndrome was defined using National Heart, Lung, and Blood Institute criteria. We concluded that hepatic steatosis, obesity, and the metabolic syndrome are independently and additively associated with increased odds of high hsCRP levels.

Usefulness of baseline obesity to predict development of a high ankle brachial index (from the Multi-Ethnic Study of Atherosclerosis).

By: Tison GH, Ndumele CE, Gerstenblith G, Allison MA, Polak JF, Szklo M.
An abnormally high ABI is associated with increased all-cause and cardiovascular mortality. The relation of obesity to incident high ABI has not been characterized. The aim of this study was to investigate the hypothesis that increased obesity — quantified by body weight, body mass index, waist circumference, and waist-to-hip-ratio — is positively associated with a high ABI (?1.3) and with mean ABI increases over a 4-year follow-up. Independent, positive, and graded associations of increasing obesity with prevalent and incident high ABI and with mean increases in ABI values over time were found. Weight and body mass index seemed to be at least as strongly, if not more strongly, associated with a high ABI than were measures of abdominal obesity.

Prevention strategies for coronary heart disease.

By: Blaha MJ, Ketlogetswe KS, Ndumele CE, Gluckman TJ, Blumenthal RS.
This state-of-the-art examination of comprehensive primary and secondary prevention strategies is a superb discussion of the impact of clinical trials and epidemiologic studies on our current national guidelines.

Preventive strategies for coronary heart disease.

By: Blaha MJ, Ketlogetswe KS, Ndumele CE, Gluckman TJ, Blumenthal RS.