The role of statins in diabetes treatment.
By: Subedi BH, Tota-Maharaj R, Silverman MG, Minder CM, Martin SS, Ashen MD, Blumenthal RS, Blaha MJ.
Diabetes is considered a risk equivalent for coronary heart disease (CHD). The use of statins for primary and secondary prevention in patients with diabetes is well established and supported by robust data from randomized, controlled trials and national guidelines. It is reasonable to match the intensity of statin therapy with patients’ baseline CVD risk.
- Year: 2015
- Topic:
Cholesterol / Lipids / Statins,
Diabetes & Metabolic Syndrome
- Read more articles by:
Roger S. Blumenthal, MD,
Michael Blaha, MD, MPH,
Marie (Dominique) Ashen, CRNP, PhD,
Seth Martin, MD, MHS
Response to letter by Dr. Lin regarding article, “HDL cholesterol subclasses, myocardial infarction, and mortality in secondary prevention: the lipoprotein investigators collaborative.
By: Martin SS, Li Y, Spertus JA, Jones SR.
The wait is over: The new cholesterol treatment guidelines are here.
By: Martin SS, Blumenthal RS.
Well-intentioned CV specialists often disagree, but we wholeheartedly support at least 90% of the new guidelines, which declare that primary prevention is here to stay. While many more adults will now qualify for statin therapy, heart-healthy dietary and exercise habits remain the foundation of primary prevention efforts. Following these new guidelines will allow clinicians to markedly reduce CVD events in their patients.
Association between lipoprotein associated phospholipase A2 mass and subclinical coronary and carotid atherosclerosis in retired national football league players.
By: Pokharel Y, Nambi V, Martin SS, Hoogeveen RC, Nasir K, Khera A, Wong ND, Jones PH, Boone J, Roberts AJ, Ballantyne CM, Virani SS.
Retired National Football League (NFL) players were reported to have high prevalence of cardiovascular risk factors. Lipoprotein Associated Phospholipase A2 (LpPLA2) has shown to be associated with cardiovascular disease in the general population, but it is unknown whether such an association exists in retired NFL players. Our objective was to assess whether LpPLA2 mass was associated with coronary artery calcium (CAC) and carotid artery plaque (CAP) in retired NFL players. LpPLA2 mass was not associated with coronary or carotid subclinical atherosclerosis in retired NFL players.
Novel biomarkers and risk factors.
By: Cheng HG, Martin SS, Jones SR.
A clinician’s guide to the updated ABCs of cardiovascular disease prevention.
By: Kohli P, Whelton SP, Hsu S, Yancy CW, Stone NJ, Chrispin J, Gilotra NA, Houston B, Ashen MD, Martin SS, Joshi PH, McEvoy JW, Gluckman TJ, Michos ED, Blaha MJ, Blumenthal RS.
To facilitate the guideline-based implementation of treatment recommendations in the ambulatory setting and to encourage participation in the multiple preventive health efforts that exist, we have organized several recent guideline updates into a simple ABCDEF approach. We would remind clinicians that evidence-based medicine is meant to inform recommendations but that synthesis of patient-specific data and use of appropriate clinical judgment in each individual situation is ultimately preferred.
- Journal:
Journal of the American Heart Association
- Year: 2014
- Topic:
Antiplatelet Therapy,
ASCVD (Atherosclerotic Cardiovascular Disease),
Blood Pressure,
Cholesterol / Lipids / Statins,
Cigarette Smoking,
Diabetes & Metabolic Syndrome,
Diet & Weight,
Exercise and Physical Fitness,
Quality of Care
- Read more articles by:
Roger S. Blumenthal, MD,
Michael Blaha, MD, MPH,
Erin Michos, MD, MHS,
Marie (Dominique) Ashen, CRNP, PhD,
Seth Martin, MD, MHS,
J. Bill McEvoy, MB BCh, MHS
Read on Pubmed
Improving lipid control following myocardial infarction.
By: Ankam J, Feldman DI, Blaha MJ, Martin SS.
Following a myocardial infarction, lipid-lowering therapy is an established intervention to reduce the risk of recurrent cardiovascular events. Prior studies show a need to improve clinical practice in this area. Here, we review the latest research and perspectives on improving postmyocardial infarction lipid control. Optimizing lipid control could further enhance clinical outcomes after myocardial infarction.
Association of high-density lipoprotein subclasses and incident coronary heart disease: The Jackson Heart and Framingham Offspring cohort studies.
By: Joshi PH, Toth PP, Lirette ST, Griswold ME, Massaro JM, Martin SS, Blaha MJ, Kulkarni KR, Khokhar AA, Correa A, D’Agostino Sr RB, Jones SR, on behalf of the Lipoprotein Investigators Collaborative (LIC) Study Group.
This study found that smaller, denser HDL3-C levels are primarily responsible for the inverse association between HDL-C and incident CHD in this diverse group of primary prevention subjects.
High-density lipoprotein subfractions: current views and clinical practice applications.
By: Martin SS, Jones SR, Toth PP.
This report prioritizes higher-resolution HDL measurement techniques that capture better the biologically and clinically important characteristics of HDL.
Non-cardiovascular effects associated with statins.
By: Desai CS, Martin SS, Blumenthal RS.
This is a state-of-art review on the possible effects of statin therapy on organs not in the cardiovascular system.
